2,5-dihydroxybenzoic acid has been researched along with 2,3-dihydroxybenzoic acid in 109 studies
*2,3-dihydroxybenzoic acid: RN given refers to parent cpd [MeSH]
*2,3-dihydroxybenzoic acid: RN given refers to parent cpd [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (3.67) | 18.7374 |
| 1990's | 69 (63.30) | 18.2507 |
| 2000's | 21 (19.27) | 29.6817 |
| 2010's | 13 (11.93) | 24.3611 |
| 2020's | 2 (1.83) | 2.80 |
| Authors | Studies |
|---|---|
| Günzler, V; Hanauske-Abel, HM; Kivirikko, KI; Majamaa, K; Myllylä, R | 1 |
| Fan, X; Lundell, D; Narula, S; Niu, X; Sun, J; Ting, P | 1 |
| Chesson, A; Duthie, GG; Russell, WR; Scobbie, L | 1 |
| Cohen, SM; Fullagar, JL; Jacobsen, JA; Miller, MT | 1 |
| Ban, HS; Ishihara, K; Nabeyama, W; Nakamura, H; Wada, H | 1 |
| Bredl, CR; Foerder, CA; Gmur, DJ; Schimpf, BA; Zager, RA | 1 |
| Cavallo, G; Chessa, MA; Milazzotto, F; Natale, E; Pensa, V; Ricci, R; Tubaro, E; Tubaro, M | 1 |
| De Mattia, G; Ferro-Luzzi, A; Ghiselli, A; Laurenti, O; Maiani, G | 1 |
| Kahn, V; Schved, F | 1 |
| Ariel, I; Chevion, M; Haskel, Y; Kitrossky, N; Udassin, R | 1 |
| Ashraf, M; Onodera, T | 1 |
| Birnbaum, LS; Blair, PC; Clark, AM; McMahon, TF; Stefanski, SA; Wilson, RE | 1 |
| Halliwell, B; Ingelman-Sundberg, M; Kaur, H; Persson, JO; Terelius, Y | 1 |
| Koppenol, WH; Maskos, Z; Rush, JD | 1 |
| Davis, WB; Husney, RM; Mays, DC; Mohammed, BS; Mohammed, JR; Sagone, AL; She, ZW | 1 |
| Floyd, RA; Henderson, R; Watson, JJ; Wong, PK | 1 |
| Grootveld, M; Halliwell, B | 1 |
| Alonso, O; Busto, R; Dietrich, WD; Ginsberg, MD; Globus, MY | 1 |
| Bttner, T; Gerlach, M; Kuhn, W; Müller, T | 1 |
| Kuo, JS; Lin, NN; Liu, L; Tsai, PJ; Yang, CS | 1 |
| Busto, R; Ginsberg, MD; Globus, MY; Lin, B; Schnippering, H | 1 |
| Coudray, C; Fatôme, M; Favier, A; Martin, S; Talla, M | 1 |
| Ashraf, M; Cai, Q; Takemura, G | 1 |
| Naoi, M; Ohkuwa, T; Sato, Y | 1 |
| Király, I; Patthy, M; Sziráki, I | 1 |
| Ito, T; Kondo, T; Sugita, Y | 1 |
| Laxdal, VA; Prasad, K | 2 |
| Hosokawa, H; Karashima, K; Obata, T; Soeda, T; Uchida, Y; Yamanaka, Y | 1 |
| Almagro, UA; Dawson, CA; Effros, RM; Ghio, AJ; Hacker, AD; Morrisey, J; Schapira, RM | 1 |
| Cross, M; Endre, ZH; Kadkhodaee, M; Towner, RA | 1 |
| Giovanni, A; Hastings, TG; Liang, LP; Zigmond, MJ | 1 |
| Hosokawa, H; Obata, T; Yamanaka, Y | 3 |
| Okuyama, T; Tomita, M; Watanabe, H; Watanabe, S | 1 |
| Berenshtein, E; Berman, ER; Chevion, M; Kitrossky, N; Ophir, A; Photiou, S; Rothman, Z | 1 |
| Andrus, PK; Hall, ED; Zhang, JR | 1 |
| Floyd, RA; Grammas, P; Liu, GJ; Wood, K | 1 |
| Busto, R; Ginsberg, MD; Globus, MY; Martinez, E; Morimoto, T | 1 |
| Gramsbergen, JB; Sloot, WN | 1 |
| Boulu, RG; Callebert, J; Lancelot, E; Plotkine, M; Revaud, ML | 1 |
| Kim, PM; Wells, PG | 1 |
| Laxdal, VA; Prasad, K; Raney, BL; Yu, M | 2 |
| Beal, MF; Matthews, RT | 2 |
| Chevion, M; Drenger, B; Elami, A; Ginosar, Y; Glantz, L; Gozal, Y; Kitrossky, N; Navot, N | 1 |
| Prasad, K | 1 |
| Chevion, M; Grinberg, LN; Kitrossky, N; Rachmilewitz, EA | 1 |
| Acworth, IN; Maher, TJ; McCabe, DR | 1 |
| Obata, T; Tamura, M; Yamanaka, Y | 2 |
| Aghabeigi, B; Haque, M; Harris, M; Henderson, B; Hodges, SJ; Wasil, M | 1 |
| Obata, T; Yamanaka, Y | 2 |
| Obata, T | 1 |
| Chevion, M; Kitrossky, N; Nagler, RM | 1 |
| Huang, NC; Quast, MJ; Wei, J | 1 |
| Ferger, B; Kuschinsky, K; Seyfried, C; van Amsterdam, C | 1 |
| Lee, KT; Liu, TZ; Tsai, LY | 1 |
| Bullock, R; Di, X; Doppenberg, EM; Rice, MR; Woodward, JJ; Young, HF | 1 |
| Hatori, K; Kondo, T; Mizuno, Y; Shimada, H; Sugita, Y | 1 |
| Blacklock, C; Campbell, G; Lawrence, JR; Paterson, JR; Wiles, D | 1 |
| Cann-Moisan, C; Caroff, J; Duine, JM; Floch, F; Mialon, P | 1 |
| Hiramatsu, M; Komatsu, M | 1 |
| Acworth, IN; Beal, MF; Bogdanov, MB; McCabe, DR | 1 |
| Bardou, L; Berthou, F; Bodenez, P; Dreano, Y; Dupont, I; Guirriec, C; Lucas, D; Stephan, N | 1 |
| Natoli, S; Violi, F | 1 |
| Colado, MI; Esteban, B; Granados, R; Green, AR; O'Shea, E | 1 |
| Blandini, F; Desideri, S; Godi, L; Mancini, F; Martignoni, E; Nappi, G; Pacchetti, C | 1 |
| Kita, T; Kubo, K; Nakashima, T; Takahashi, M; Wagner, GC | 1 |
| Floyd, RA; He, QP; Li, PA; Liu, GJ; Siesjö, BK | 1 |
| Jantze, H; Rauca, C; Zerbe, R | 1 |
| Bani, M; Brogin, G; Hengstler, JG; Oesch, F; Strolin-Benedetti, M | 1 |
| Bartsch, H; Owen, RW; Spiegelhalder, B | 1 |
| Amiridze, N; Brown, OR; Dang, Y | 1 |
| Gronow, G; Mályusz, M; Moussavian, M | 1 |
| Camp, DM; LeWitt, PA; Loeffler, DA | 1 |
| Exner, M; Gmeiner, BM; Held, I; Hermann, M; Hofbauer, R; Kapiotis, S; Seelos, C; Speiser, W | 1 |
| Hara, A; Kusakari, J; Senarita, M; Serizawa, F; Tabuchi, K | 1 |
| Ferger, B; Teismann, P | 1 |
| Mohanakumar, KP; Muralikrishnan, D; Thomas, B | 1 |
| Brus, R; Kostrzewa, JP; Kostrzewa, RM | 1 |
| Griffiths, RD; Jackson, MJ; McArdle, A; Pattwell, D | 1 |
| Banerjee, R; Mohanakumar, KP; Sairam, K; Saravanan, KS | 1 |
| Horiguchi, T; Inamasu, J; Kawase, T; Ogino, M; Shimizu, K; Suga, S | 1 |
| Alessandri, B; Bullock, MR; Chao, DL; Kwon, TH; Malloy, K; Sun, D | 1 |
| Adibhatla, RM; Dempsey, RJ; Hatcher, JF | 1 |
| Keilhoff, G; Krug, M; Rauca, C; Wiswedel, I; Zerbe, R | 1 |
| Berenshtein, E; Chevion, M; Drenger, B; Gozal, Y; Raphael, J; Rivo, J | 1 |
| Dahchour, A; De Witte, P; Lallemand, F; Ward, RJ | 1 |
| Burger, R; Gruber, M; Lindner, R; Wiesner, G | 1 |
| Arai, M; Bao, N; Chen, XH; Fujiwara, H; Kobayashi, H; Maruyama, R; Minatoguchi, S; Misao, Y; Onogi, H; Takemura, G; Uno, Y; Yamaki, T; Yasuda, S | 1 |
| Endo, T; Hara, S; Kuriiwa, F; Mizukami, H | 1 |
| Bao, N; Fujiwara, H; Fujiwara, T; Iwasa, M; Kawamura, I; Kobayashi, H; Minatoguchi, S; Nishigaki, K; Sumi, S; Takemura, G; Yamada, Y; Yasuda, S; Zhang, Z | 1 |
| Bosco, GM; Camporesi, EM; Chen, C; Xie, Y; Yang, ZJ | 1 |
| Gołembiowska, K; Kuter, K; Nowak, P; Ossowska, K | 1 |
| Lares-Asseff, I; Lazalde-Ramos, BP; Sosa-Macías, M; Villanueva-Fierro, I; Yahuaca-Mendoza, P; Zamora-Perez, A | 1 |
| Gan, SS; Halitschke, R; Liu, CJ; Yin, C; Zhang, K | 1 |
| Aldalati, AM; AlTinawi, BM; Azouz, HJ; Ganguly, P; Juurlink, BH | 1 |
| Atwell, S; Chapple, C; Dilkes, BP; Li, X; Mo, H; Svedin, E | 1 |
| Goyal, RN; Gupta, P; Purushotham, M | 1 |
| Chen, HY; Li, X | 1 |
| Berger, T; Botta, A; Huang, X; Liu, Y; Mak, TW; Perry, CGR; Ramos, SV; Song, E; Sung, HK; Sweeney, G; Turnbull, PC; Wheeler, MB; Wilson, DJ | 1 |
| Chen, L; Hou, BK; Huang, XX; Li, YJ; Liu, Q; Zhu, GQ | 1 |
| Dereziński, P; Muszalska-Kolos, I; Plewa, S; Wróblewska, KB | 1 |
| Bhat, GJ; Kumar, DR; Patel, J; Sankaranarayanan, R | 1 |
| Gupta, P; Rohatgi, A | 1 |
2 review(s) available for 2,5-dihydroxybenzoic acid and 2,3-dihydroxybenzoic acid
| Article | Year |
|---|---|
Hydroxybenzoic acid isomers and the cardiovascular system.
Topics: Aspirin; Benzyl Alcohols; Cardiovascular System; Diet; Gentisates; Glucosides; Humans; Hydroxybenzoates; Isothiocyanates; Oxidative Stress; Phytochemicals; Sulfoxides | 2014 |
Do Aspirin and Flavonoids Prevent Cancer through a Common Mechanism Involving Hydroxybenzoic Acids?-The Metabolite Hypothesis.
Topics: Animals; Aspirin; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Flavonoids; Fruit; Gallic Acid; Gentisates; Humans; Hydroxybenzoates; MAP Kinase Signaling System | 2020 |
2 trial(s) available for 2,5-dihydroxybenzoic acid and 2,3-dihydroxybenzoic acid
| Article | Year |
|---|---|
Peripheral markers of oxidative stress in Parkinson's disease. The role of L-DOPA.
Topics: Antiparkinson Agents; Biomarkers; Blood Platelets; Dopamine; Female; Gentisates; Humans; Hydroxybenzoates; Hydroxyl Radical; In Vitro Techniques; Levodopa; Linear Models; Male; Middle Aged; Oxidative Stress; Parkinson Disease; Sodium Salicylate; Superoxide Dismutase; Tyrosine | 1999 |
Graphene modified glassy carbon sensor for the determination of aspirin metabolites in human biological samples.
Topics: Adult; Aspirin; Carbon; Dielectric Spectroscopy; Electrodes; Female; Gentisates; Humans; Hydroxybenzoates; Limit of Detection; Male; Microscopy, Electron, Scanning; Young Adult | 2015 |
105 other study(ies) available for 2,5-dihydroxybenzoic acid and 2,3-dihydroxybenzoic acid
| Article | Year |
|---|---|
Partial identity of the 2-oxoglutarate and ascorbate binding sites of prolyl 4-hydroxylase.
Topics: Animals; Ascorbic Acid; Binding Sites; Chick Embryo; Ketoglutaric Acids; Kinetics; Phenols; Procollagen-Proline Dioxygenase; Protein Binding; Structure-Activity Relationship; Substrate Specificity | 1986 |
Inhibition of fucosyltransferase VII by gallic acid and its derivatives.
Topics: Catechin; Ellagic Acid; Enzymes; Fucosyltransferases; Gallic Acid; Humans; Manganese | 2004 |
Inhibition of 15-lipoxygenase-catalysed oxygenation of arachidonic acid by substituted benzoic acids.
Topics: Arachidonate 15-Lipoxygenase; Arachidonic Acid; Benzoates; Catalysis; Colon; Enzyme Inhibitors; Humans; Lipoxygenase Inhibitors; Oxidation-Reduction; Oxygen; Structure-Activity Relationship | 2008 |
Identifying chelators for metalloprotein inhibitors using a fragment-based approach.
Topics: Antigens, Bacterial; Bacterial Toxins; Chelating Agents; Copper; Drug Design; Humans; Hydroxyquinolines; Iron; Ligands; Lipoxygenase Inhibitors; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Monophenol Monooxygenase; Nitric Oxide Synthase Type II; Recombinant Proteins; Small Molecule Libraries; Structure-Activity Relationship; Sulfonamides; Zinc | 2011 |
Discovery of (2-aminophenyl)methanol as a new molecular chaperone that rescues the localization of P123S mutant pendrin stably expressed in HEK293 cells.
Topics: Amino Acid Substitution; Benzyl Alcohols; Cell Membrane; Goiter, Nodular; Hearing Loss, Sensorineural; HEK293 Cells; Humans; Membrane Transport Proteins; Microscopy, Fluorescence; Salicylates; Sulfate Transporters | 2017 |
Evidence against increased hydroxyl radical production during oxygen deprivation-reoxygenation proximal tubular injury.
Topics: Acute Kidney Injury; Animals; Free Radicals; Gentisates; Hydroxides; Hydroxybenzoates; Hydroxyl Radical; Hypoxia; In Vitro Techniques; Kidney Tubules, Proximal; L-Lactate Dehydrogenase; Male; Rats; Rats, Inbred Strains; Reperfusion Injury | 1992 |
Demonstration of the formation of hydroxyl radicals in acute myocardial infarction in man using salicylate as probe.
Topics: Aspirin; Chromatography, High Pressure Liquid; Female; Free Radicals; Gentisates; Humans; Hydroxides; Hydroxybenzoates; Hydroxyl Radical; Isosorbide Dinitrate; Male; Middle Aged; Myocardial Infarction; Tissue Plasminogen Activator | 1992 |
Salicylate hydroxylation as an early marker of in vivo oxidative stress in diabetic patients.
Topics: Adult; Aspirin; Diabetes Mellitus, Type 1; Female; Gentisates; Humans; Hydroxybenzoates; Hydroxylation; Male; Oxidation-Reduction; Reactive Oxygen Species; Salicylates; Thiobarbiturates | 1992 |
Effect of different isomers of dihydroxybenzoic acids (DBA) on the rate of DL-dopa oxidation by mushroom tyrosinase.
Topics: Basidiomycota; Dihydroxyphenylalanine; Drug Synergism; Gentisates; Hydroxybenzoates; Isomerism; Kinetics; Levodopa; Models, Chemical; Monophenol Monooxygenase; Oxidation-Reduction; Plant Proteins; Structure-Activity Relationship | 1992 |
Salicylate as an in vivo free radical trap: studies on ischemic insult to the rat intestine.
Topics: Animals; Disease Models, Animal; Free Radicals; Gentisates; Hydroxides; Hydroxybenzoates; Hydroxyl Radical; Intestines; Male; Rats; Reperfusion Injury; Salicylates; Salicylic Acid | 1991 |
Detection of hydroxyl radicals in the post-ischemic reperfused heart using salicylate as a trapping agent.
Topics: Animals; Chromatography, High Pressure Liquid; Gentisates; Hydroxides; Hydroxybenzoates; Hydroxyl Radical; Hydroxylation; In Vitro Techniques; Ischemia; Male; Myocardial Reperfusion; Oxygen; Rats; Rats, Inbred Strains; Salicylates; Salicylic Acid | 1991 |
Comparative acute nephrotoxicity of salicylic acid, 2,3-dihydroxybenzoic acid, and 2,5-dihydroxybenzoic acid in young and middle aged Fischer 344 rats.
Topics: Acetylglucosaminidase; Administration, Oral; Aging; Alanine Transaminase; Alkaline Phosphatase; Animals; Gentisates; Glycosuria; Hydroxybenzoates; Kidney; Male; Rats; Rats, Inbred F344; Salicylates; Salicylic Acid | 1991 |
Hydroxylation of salicylate by microsomal fractions and cytochrome P-450. Lack of production of 2,3-dihydroxybenzoate unless hydroxyl radical formation is permitted.
Topics: Animals; Cytochrome P-450 Enzyme System; Free Radical Scavengers; Gentisates; Hydroxides; Hydroxybenzoates; Hydroxylation; Lipid Bilayers; Microsomes, Liver; Rabbits; Rats; Salicylates; Salicylic Acid; Substrate Specificity | 1991 |
The hydroxylation of the salicylate anion by a Fenton reaction and T-radiolysis: a consideration of the respective mechanisms.
Topics: Azides; Chemical Phenomena; Chemistry; Edetic Acid; Free Radicals; Gamma Rays; Gentisates; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydroxybenzoates; Hydroxylation; Iron; Kinetics; Oxidation-Reduction; Salicylates | 1990 |
Hydroxylation of salicylate by activated neutrophils.
Topics: Amitrole; Azides; Chromatography, High Pressure Liquid; Cyanides; Gentisates; Glutathione; Humans; Hydroxybenzoates; Hydroxylation; Neutrophils; Peroxidase; Salicylates; Salicylic Acid; Superoxide Dismutase; Tetradecanoylphorbol Acetate | 1989 |
Use of salicylate with high pressure liquid chromatography and electrochemical detection (LCED) as a sensitive measure of hydroxyl free radicals in adriamycin treated rats.
Topics: Animals; Chromatography, High Pressure Liquid; Doxorubicin; Electrochemistry; Female; Free Radicals; Gentisates; Heart; Hydroxides; Hydroxybenzoates; Hydroxyl Radical; Rats; Rats, Inbred F344; Salicylates; Salicylic Acid | 1986 |
Aromatic hydroxylation as a potential measure of hydroxyl-radical formation in vivo. Identification of hydroxylated derivatives of salicylate in human body fluids.
Topics: Adult; Chromatography, High Pressure Liquid; Electrochemistry; Free Radicals; Gentisates; Hippurates; Humans; Hydroxides; Hydroxybenzoates; Hydroxyl Radical; Hydroxylation; Male; Salicylates; Salicylic Acid; Synovial Fluid | 1986 |
Glutamate release and free radical production following brain injury: effects of posttraumatic hypothermia.
Topics: Animals; Brain Injuries; Free Radicals; Gentisates; Glutamic Acid; Hydroxybenzoates; Hydroxyl Radical; Hypothermia; Male; Microdialysis; Rats; Rats, Sprague-Dawley | 1995 |
Aspirin as a free radical scavenger: consequences for therapy of cerebrovascular ischemia.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Aspirin; Cerebrovascular Disorders; Cyclooxygenase Inhibitors; Female; Free Radical Scavengers; Gentisates; Humans; Hydroxybenzoates; Male; Neuroprotective Agents; Platelet Aggregation Inhibitors; Salicylates; Salicylic Acid | 1995 |
Elevated extracellular glutamate levels increased the formation of hydroxyl radical in the striatum of anesthetized rat.
Topics: Anesthesia; Animals; Chromatography, High Pressure Liquid; Corpus Striatum; Extracellular Space; Gentisates; Glutamic Acid; Hydroxybenzoates; Hydroxyl Radical; Hydroxylation; Kinetics; Male; Rats; Rats, Sprague-Dawley; Salicylates; Salicylic Acid | 1995 |
Detection of free radical activity during transient global ischemia and recirculation: effects of intraischemic brain temperature modulation.
Topics: Animals; Body Temperature; Corpus Striatum; Dialysis; Free Radicals; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Ischemic Attack, Transient; Kinetics; Male; Rats; Rats, Wistar; Reperfusion; Salicylates; Salicylic Acid | 1995 |
High-performance liquid chromatography-electrochemical determination of salicylate hydroxylation products as an in vivo marker of oxidative stress.
Topics: Adult; Aspirin; Calibration; Chromatography, High Pressure Liquid; Female; Free Radical Scavengers; Gentisates; Humans; Hydroxybenzoates; Hydroxyl Radical; Male; Oxidative Stress; Reproducibility of Results; Salicylates; Salicylic Acid; Thiobarbituric Acid Reactive Substances | 1995 |
Antioxidative properties of histidine and its effect on myocardial injury during ischemia/reperfusion in isolated rat heart.
Topics: Adenosine Triphosphate; Animals; Ascorbic Acid; Chromatography, High Pressure Liquid; Disease Models, Animal; Free Radical Scavengers; Gentisates; Glutaral; Heart Ventricles; Histidine; Hydrogen Peroxide; Hydroxybenzoates; Hydroxyl Radical; L-Lactate Dehydrogenase; Male; Myocardial Reperfusion Injury; Phosphates; Phosphocreatine; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Superoxides; Tissue Embedding; Ventricular Function, Left | 1995 |
Hydroxyl radical formation in diabetic rats induced by streptozotocin.
Topics: Animals; Blood Glucose; Chromatography, High Pressure Liquid; Diabetes Mellitus, Experimental; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Male; Rats; Rats, Wistar; Streptozocin | 1995 |
Separation of dihydroxybenzoates, indicators of in-vivo hydroxyl free radical formation, in the presence of transmitter amines and some metabolites in rodent brain, using high-performance liquid chromatography with electrochemical detection.
Topics: Animals; Biogenic Amines; Chromatography, High Pressure Liquid; Corpus Striatum; Electrochemistry; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Mice; Mice, Inbred C57BL | 1995 |
Bromocriptine scavenges methamphetamine-induced hydroxyl radicals and attenuates dopamine depletion in mouse striatum.
Topics: Animals; Bromocriptine; Corpus Striatum; Dopamine; Free Radical Scavengers; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Iron Chelating Agents; Kinetics; Male; Methamphetamine; Mice; Mice, Inbred C57BL; Salicylates; Salicylic Acid | 1994 |
Evaluation of hydroxyl radical-scavenging property of purpurogallin using high pressure liquid chromatography.
Topics: Antioxidants; Benzocycloheptenes; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Food Preservatives; Free Radical Scavengers; Gentisates; Hydrogen Peroxide; Hydroxybenzoates; Hydroxyl Radical; Hydroxylation; Photolysis; Salicylates; Salicylic Acid; Ultraviolet Rays | 1994 |
Hydroxyl radical-scavenging property of indomethacin.
Topics: Chromatography, High Pressure Liquid; Free Radical Scavengers; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Indomethacin; Photolysis; Sensitivity and Specificity; Ultraviolet Rays | 1994 |
Myocardial microdialysis of salicylic acid to detect hydroxyl radical generation during ischemia.
Topics: Animals; Chromatography, High Pressure Liquid; Dogs; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Microchemistry; Microdialysis; Myocardial Contraction; Myocardial Ischemia; Salicylates; Salicylic Acid | 1995 |
Hydroxyl radical production and lung injury in the rat following silica or titanium dioxide instillation in vivo.
Topics: Animals; Bronchoalveolar Lavage Fluid; Dust; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Hydroxylation; Lung; Lung Injury; Organ Size; Pulmonary Fibrosis; Rats; Rats, Sprague-Dawley; Salicylates; Salicylic Acid; Silicon Dioxide; Silicosis; Titanium | 1995 |
Hydroxyl radical generation following ischaemia-reperfusion in cell-free perfused rat kidney.
Topics: Animals; Chromatography, High Pressure Liquid; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Hypoxia; Ischemia; Kidney; Male; Rats; Rats, Wistar; Reperfusion; Salicylates | 1995 |
Estimating hydroxyl radical content in rat brain using systemic and intraventricular salicylate: impact of methamphetamine.
Topics: Animals; Biogenic Monoamines; Brain; Corpus Striatum; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Hydroxylation; Injections, Intraperitoneal; Injections, Intraventricular; Methamphetamine; Rats; Rats, Sprague-Dawley; Salicylates; Salicylic Acid | 1995 |
Effect of ferrous iron on the generation of hydroxyl free radicals by liver microdialysis perfusion of salicylate.
Topics: Animals; Extracellular Space; Ferrous Compounds; Free Radicals; Gentisates; Hydroxybenzoates; Hydroxylation; Iron Chelating Agents; Liver; Metals; Microdialysis; Perfusion; Rats; Rats, Wistar; Salicylates; Salicylic Acid | 1993 |
In vivo monitoring of norepinephrine and hydroxyl free radical generation by ferrous iron in the myocardium with a microdialysis technique.
Topics: Animals; Chromatography, High Pressure Liquid; Electrochemistry; Ferrous Compounds; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Iron Chelating Agents; Male; Microdialysis; Myocardium; Norepinephrine; Perfusion; Rats; Rats, Wistar | 1993 |
Quantitation of the hydroxyl radical adducts of salicylic acid by micellar electrokinetic capillary chromatography: oxidizing species formed by a Fenton reaction.
Topics: Chromatography; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Iron; Micelles; Salicylates; Salicylic Acid | 1994 |
In vivo monitoring of norepinephrine and .OH generation on myocardial ischemic injury by dialysis technique.
Topics: Animals; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Microdialysis; Myocardial Ischemia; Myocardial Reperfusion; Norepinephrine; Rats; Rats, Wistar | 1994 |
Hydroxyl radical generation in the cat retina during reperfusion following ischemia.
Topics: Animals; Cats; Eye Proteins; Free Radicals; Gentisates; Hydroxybenzoates; Reactive Oxygen Species; Reperfusion Injury; Retina; Sodium Salicylate; Time Factors | 1993 |
Age-related regional changes in hydroxyl radical stress and antioxidants in gerbil brain.
Topics: Aging; Animals; Antioxidants; Ascorbic Acid; Body Water; Brain; Cerebral Cortex; Corpus Striatum; Gentisates; Gerbillinae; Glutathione; Hippocampus; Hydroxybenzoates; Hydroxyl Radical; Male; Neurons; Organ Specificity; Oxidation-Reduction; Pyramidal Tracts; Vitamin E | 1993 |
Anoxia/reoxygenation induces hydroxyl free radical formation in brain microvessels.
Topics: Animals; Brain; Catalase; Chromatography, High Pressure Liquid; Free Radicals; Gentisates; Hydroxides; Hydroxybenzoates; Hydroxyl Radical; Male; Microcirculation; Oxygen; Rats; Rats, Sprague-Dawley; Salicylates; Salicylic Acid; Superoxides | 1993 |
Simultaneous measurement of salicylate hydroxylation and glutamate release in the penumbral cortex following transient middle cerebral artery occlusion in rats.
Topics: Acid-Base Imbalance; Analysis of Variance; Animals; Cerebral Cortex; Cerebrovascular Circulation; Chromatography, High Pressure Liquid; Free Radical Scavengers; Gentisates; Glutamic Acid; Hydroxybenzoates; Hydroxylation; Iron Chelating Agents; Ischemic Attack, Transient; Laser-Doppler Flowmetry; Male; Rats; Rats, Sprague-Dawley; Regression Analysis; Salicylates; Salicylic Acid | 1996 |
Detection of salicylate and its hydroxylated adducts 2,3- and 2,5-dihydroxybenzoic acids as possible indices for in vivo hydroxyl radical formation in combination with catechol- and indoleamines and their metabolites in cerebrospinal fluid and brain tissu
Topics: Animals; Biogenic Amines; Catechols; Chromatography, High Pressure Liquid; Electrochemistry; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Indoles; Magnesium; Male; Manganese Poisoning; Neostriatum; Rats; Rats, Wistar; Reference Standards; Salicylates; Salicylic Acid; Spectrophotometry, Ultraviolet | 1995 |
Detection of hydroxyl radicals in rat striatum during transient focal cerebral ischemia: possible implication in tissue damage.
Topics: Analysis of Variance; Animals; Cerebral Infarction; Corpus Striatum; Disease Models, Animal; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Ischemic Attack, Transient; Male; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 1995 |
Phenytoin-initiated hydroxyl radical formation: characterization by enhanced salicylate hydroxylation.
Topics: Animals; Biotransformation; Female; Gentisates; Glucuronidase; Hydrolysis; Hydroxybenzoates; Hydroxyl Radical; Hydroxylation; Mice; Paraquat; Phenytoin; Salicylates; Salicylic Acid; Teratogens | 1996 |
Antioxidant activity of allicin, an active principle in garlic.
Topics: Animals; Antioxidants; Chromatography, High Pressure Liquid; Disulfides; Free Radical Scavengers; Garlic; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Lipid Peroxidation; Liver; Malondialdehyde; Plants, Medicinal; Rabbits; Reactive Oxygen Species; Salicylates; Salicylic Acid; Sulfinic Acids; Tablets | 1995 |
Evaluation of hydroxyl radical-scavenging property of garlic.
Topics: Animals; Chromatography, High Pressure Liquid; Free Radical Scavengers; Garlic; Gentisates; Hot Temperature; Hydroxybenzoates; Hydroxyl Radical; Lipid Peroxidation; Liver; Malondialdehyde; Photolysis; Plant Extracts; Plants, Medicinal; Rabbits; Salicylates; Salicylic Acid; Sensitivity and Specificity; Superoxides; Ultraviolet Rays | 1996 |
Increased 3-nitrotyrosine in brains of Apo E-deficient mice.
Topics: Animals; Apolipoproteins E; Biomarkers; Brain Chemistry; Free Radical Scavengers; Free Radicals; Gentisates; Hydroxybenzoates; Mice; Mice, Inbred C57BL; Oxidative Stress; Salicylates; Salicylic Acid; Tyrosine | 1996 |
Halothane prevents postischemic production of hydroxyl radicals in the canine heart.
Topics: Anesthetics, Inhalation; Animals; Dogs; Gentisates; Halothane; Hydroxybenzoates; Hydroxyl Radical; Myocardial Ischemia; Myocardium | 1997 |
Hydroxyl radical-scavenging property of secoisolariciresinol diglucoside (SDG) isolated from flax-seed.
Topics: Butylene Glycols; Chromatography, High Pressure Liquid; Free Radical Scavengers; Gentisates; Glucosides; Hydroxybenzoates; Hydroxyl Radical; Lipid Peroxidation; Seeds; Sensitivity and Specificity; Ultraviolet Rays | 1997 |
Hydroxyl radical generation in beta-thalassemic red blood cells.
Topics: beta-Thalassemia; Catechols; Erythrocytes; Gentisates; Humans; Hydroxybenzoates; Hydroxyl Radical; In Vitro Techniques; Iron; Oxidation-Reduction; Salicylates; Salicylic Acid | 1995 |
Improved method for the estimation of hydroxyl free radical levels in vivo based on liquid chromatography with electrochemical detection.
Topics: Animals; Benzoates; Cerebral Cortex; Chromatography, High Pressure Liquid; Corpus Striatum; Dizocilpine Maleate; Drug Stability; Excitatory Amino Acid Antagonists; Free Radicals; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Hydroxylation; Kidney; Liver; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Salicylates; Sensitivity and Specificity | 1997 |
Comparative study of .OH generation in brain, heart and liver using microdialysis.
Topics: Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Liver; Male; Microdialysis; Myocardium; Rats; Rats, Wistar; Salicylates | 1997 |
The role of oxygen free radicals in idiopathic facial pain.
Topics: Administration, Oral; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Case-Control Studies; Chronic Disease; Cytokines; Dinoprostone; Facial Pain; Female; Free Radicals; Gentisates; Humans; Hydroxybenzoates; Hydroxyeicosatetraenoic Acids; Iron Chelating Agents; Leukotriene B4; Male; Mastication; Middle Aged; Reactive Oxygen Species; Synovial Fluid; Temporomandibular Joint; Temporomandibular Joint Dysfunction Syndrome; Thiobarbituric Acid Reactive Substances | 1997 |
Cardiac microdialysis of salicylic acid .OH generation on nonenzymatic oxidation by norepinephrine in rat heart.
Topics: Animals; Dose-Response Relationship, Drug; Gentisates; Hydroxybenzoates; Hydroxyl Radical; In Vitro Techniques; Male; Microdialysis; Monoamine Oxidase Inhibitors; Myocardium; Norepinephrine; Pargyline; Rats; Rats, Wistar; Salicylates; Salicylic Acid | 1997 |
Use of microdialysis for in-vivo monitoring of hydroxyl free-radical generation in the rat.
Topics: Animals; Brain; Chromatography, High Pressure Liquid; Electric Stimulation; Gentisates; Hydrogen Peroxide; Hydroxybenzoates; Hydroxyl Radical; Iron; Ischemia; Jejunum; Liver; Male; Microdialysis; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Myocardium; Norepinephrine; Pargyline; Rats; Rats, Wistar; Reperfusion Injury; Salicylates; Superoxides; Sympathetic Nervous System | 1997 |
Coenzyme Q10 in the central nervous system and its potential usefulness in the treatment of neurodegenerative diseases.
Topics: Administration, Oral; Animals; Antioxidants; Brain; Coenzymes; Corpus Striatum; Electron Transport; Gentisates; Humans; Hydroxybenzoates; Injections; Liver; Male; Malonates; Neurodegenerative Diseases; Neuroprotective Agents; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Sprague-Dawley; Salicylates; Salicylic Acid; Ubiquinone | 1997 |
Antioxidant activity of rat parotid saliva.
Topics: Ancitabine; Animals; Antimetabolites, Antineoplastic; Antioxidants; Ascorbic Acid; Catechols; Copper; Free Radicals; Gentisates; Hydroxybenzoates; Iron; Iron Chelating Agents; Male; Manganese; Metals; Oxidation-Reduction; Parasympathomimetics; Parotid Gland; Pilocarpine; Protein Binding; Rats; Rats, Wistar; Salicylates; Saliva; Salivary Proteins and Peptides; Wound Healing | 1997 |
Hydroxyl radical formation in hyperglycemic rats during middle cerebral artery occlusion/reperfusion.
Topics: Animals; Arterial Occlusive Diseases; Cerebral Arteries; Cerebral Infarction; Enzyme Inhibitors; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Hyperglycemia; In Vitro Techniques; Magnetic Resonance Imaging; Male; Microdialysis; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 1997 |
Evidence of hydroxyl free radical generation by calcium overload in rat myocardium.
Topics: Animals; Calcium; Cardiotonic Agents; Dose-Response Relationship, Drug; Gentisates; Heart; Heart Ventricles; Hydroxybenzoates; Hydroxyl Radical; Hydroxylation; Male; Microdialysis; Mixed Function Oxygenases; Myocardium; Ouabain; Rats; Rats, Wistar; Salicylates; Salicylic Acid | 1997 |
Effects of alpha-phenyl-tert-butylnitrone and selegiline on hydroxyl free radicals in rat striatum produced by local application of glutamate.
Topics: Administration, Topical; Animals; Corpus Striatum; Cyclic N-Oxides; Free Radical Scavengers; Gentisates; Glutamic Acid; Hydroxybenzoates; Hydroxyl Radical; Male; Microdialysis; Monoamine Oxidase Inhibitors; Nitrogen Oxides; Rats; Rats, Wistar; Selegiline | 1998 |
Evidence for accelerated generation of hydroxyl radicals in experimental obstructive jaundice of rats.
Topics: Animals; Cholestasis, Intrahepatic; Common Bile Duct Diseases; Constriction; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Leukocyte Count; Male; Rats; Rats, Wistar | 1998 |
Increased free radical production due to subdural hematoma in the rat: effect of increased inspired oxygen fraction.
Topics: Acute Disease; Animals; Blood Gas Analysis; Free Radicals; Gentisates; Hematoma, Subdural; Hydroxybenzoates; Male; Oxygen; Oxyhemoglobins; Rats; Rats, Sprague-Dawley; Time Factors | 1998 |
Talipexole protects dopaminergic neurons from methamphetamine toxicity in C57BL/6N mouse.
Topics: Animals; Azepines; Central Nervous System Stimulants; Chromatography, High Pressure Liquid; Dopamine; Dopamine Agonists; Enzyme Induction; Free Radical Scavengers; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Male; Methamphetamine; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Parkinson Disease, Secondary; Receptors, Dopamine D2; Salicylates; Salicylic Acid; Tyrosine 3-Monooxygenase | 1998 |
The identification of salicylates as normal constituents of serum: a link between diet and health?
Topics: Chromatography, High Pressure Liquid; Diet; Gas Chromatography-Mass Spectrometry; Gentisates; Humans; Hydroxybenzoates; Salicylates; Salicylic Acid | 1998 |
Simultaneous measurement of monoamines, their metabolites and 2,3- and 2,5-dihydroxybenzoates by high-performance liquid chromatography with electrochemical detection. Application to rat brain dialysates.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Monoamines; Corpus Striatum; Dopamine; Gentisates; Homovanillic Acid; Hydroxybenzoates; Hydroxyindoleacetic Acid; Hydroxyl Radical; Methoxyhydroxyphenylglycol; Norepinephrine; Oxygen; Rats; Restraint, Physical; Serotonin | 1998 |
Glibenclamide, an antagonist of ATP sensitive K+ channels, blocks free radical generation in the rat myocardium.
Topics: Allopurinol; Animals; Enzyme Inhibitors; Free Radicals; Gentisates; Glyburide; Heart; Hydroxybenzoates; Male; Microdialysis; Myocardium; Perfusion; Potassium Channel Blockers; Potassium Channels; Potassium Chloride; Rats; Rats, Wistar; Sodium Salicylate; Sucrose | 1998 |
Measurement of hydroxyl radical by salicylate in striatum of intact brain.
Topics: Animals; Chromatography, High Pressure Liquid; Convulsants; Corpus Striatum; Gentisates; Glutarates; Hydroxybenzoates; Hydroxyl Radical; Male; Methylguanidine; Microdialysis; Rats; Rats, Wistar; Salicylates | 1999 |
Estimation of hydroxyl free radical levels in vivo based on liquid chromatography with electrochemical detection.
Topics: Chromatography, Liquid; Electrochemistry; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Models, Chemical; Oxidative Stress; Parabens; Salicylic Acid; Tyrosine | 1999 |
Involvement of cytochromes P-450 2E1 and 3A4 in the 5-hydroxylation of salicylate in humans.
Topics: Alcoholism; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Gentisates; Humans; Hydroxybenzoates; Hydroxylation; Kinetics; Microsomes, Liver; Mixed Function Oxygenases; Salicylates | 1999 |
[Oxidative stress and hypercholesterolemia: increase of radical hydroxyl in patients with hypercholesterolemia].
Topics: Adult; Aged; Cholesterol; Chromatography, High Pressure Liquid; Chromatography, Liquid; Data Interpretation, Statistical; Female; Gentisates; Humans; Hydroxybenzoates; Hydroxyl Radical; Hypercholesterolemia; Leukocytes; Male; Middle Aged; Oxidative Stress | 1999 |
In vivo evidence against clomethiazole being neuroprotective against MDMA ('ecstasy')-induced degeneration of rat brain 5-HT nerve terminals by a free radical scavenging mechanism.
Topics: Animals; Biotransformation; Body Temperature; Brain; Cerebral Cortex; Chlormethiazole; Corpus Striatum; Free Radical Scavengers; Gentisates; Hippocampus; Hydroxybenzoates; Hydroxyindoleacetic Acid; Kinetics; Male; Microdialysis; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Degeneration; Nerve Endings; Neuroprotective Agents; Paroxetine; Rats; Salicylic Acid; Serotonin | 1999 |
Hydroxyl radical formation following methamphetamine administration to rats.
Topics: Animals; Body Temperature; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Gentisates; Hippocampus; Hydroxybenzoates; Hydroxyl Radical; Injections, Intraventricular; Male; Methamphetamine; Rats; Rats, Wistar; Salicylates; Serotonin | 1999 |
Production of hydroxyl free radical by brain tissues in hyperglycemic rats subjected to transient forebrain ischemia.
Topics: Animals; Brain; Brain Injuries; Brain Ischemia; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Hyperglycemia; Male; Rats; Rats, Wistar; Reactive Oxygen Species; Reperfusion Injury; Salicylic Acid; Tissue Distribution | 1999 |
Formation of free hydroxyl radicals after pentylenetetrazol-induced seizure and kindling.
Topics: Animals; Brain; Convulsants; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Kindling, Neurologic; Male; Pentylenetetrazole; Rats; Rats, Wistar; Seizures | 1999 |
Association of cytochrome P450 induction with oxidative stress in vivo as evidenced by 3-hydroxylation of salicylate.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; beta-Naphthoflavone; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Induction; Enzyme Inhibitors; Gentisates; Hydroxybenzoates; Hydroxylation; Male; Oxidative Stress; Oxidoreductases, N-Demethylating; Phenobarbital; Proadifen; Rats; Rats, Sprague-Dawley; Salicylates | 1999 |
Generation of reactive oxygen species by the faecal matrix.
Topics: Ascorbic Acid; Bacteria; Catechols; Chromatography, High Pressure Liquid; Edetic Acid; Feces; Free Radical Scavengers; Gentisates; Humans; Hydroxybenzoates; Hydroxyl Radical; Hypoxanthine; Phytic Acid; Reactive Oxygen Species; Salicylic Acid; Xanthine Oxidase | 2000 |
Hydroxyl radicals detected via brain microdialysis in rats breathing air and during hyperbaric oxygen convulsions.
Topics: Air; Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Corpus Striatum; Electron Spin Resonance Spectroscopy; Epilepsy, Tonic-Clonic; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Hyperbaric Oxygenation; Male; Microdialysis; Rats; Rats, Sprague-Dawley; Salicylates | 1999 |
Effect of hydroxyl radical scavengers in renal cortical cells.
Topics: Animals; Benzoates; Free Radical Scavengers; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Hydroxylation; Kidney Cortex; Rats; Rats, Wistar | 1999 |
L-DOPA does not enhance hydroxyl radical formation in the nigrostriatal dopamine system of rats with a unilateral 6-hydroxydopamine lesion.
Topics: Animals; Cerebellum; Corpus Striatum; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Injections; Levodopa; Male; Mesencephalon; Methamphetamine; Microdialysis; Osmolar Concentration; Oxidopamine; Rats; Rats, Sprague-Dawley; Salicylates; Substantia Nigra | 2000 |
The salicylate metabolite gentisic acid, but not the parent drug, inhibits glucose autoxidation-mediated atherogenic modification of low density lipoprotein.
Topics: Arteriosclerosis; Aspirin; Cells, Cultured; Diabetic Angiopathies; Endothelium, Vascular; Gentisates; Glucose; Humans; Hydroxybenzoates; Iron Chelating Agents; Lipoproteins, LDL; Male; Oxidation-Reduction; Prodrugs; Reactive Oxygen Species; Salicylic Acid; Thromboplastin | 2000 |
Hydroxyl radical formation in the perilymph of asphyxic guinea pig.
Topics: Animals; Asphyxia; Chromatography, High Pressure Liquid; Electrochemistry; Gentisates; Guinea Pigs; Hydroxybenzoates; Hydroxyl Radical; Perilymph; Salicylates | 2000 |
The salicylate hydroxylation assay to measure hydroxyl free radicals induced by local application of glutamate in vivo or induced by the Fenton reaction in vitro.
Topics: Animals; Dose-Response Relationship, Drug; Gentisates; Glutamic Acid; Hydroxybenzoates; Hydroxyl Radical; Hydroxylation; Male; Methods; Microdialysis; Rats; Rats, Wistar; Salicylates | 2000 |
Neuroprotection by sodium salicylate against 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine-induced neurotoxicity.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Catalepsy; Cyclooxygenase Inhibitors; Dopamine; Dopamine Agents; Dyskinesia, Drug-Induced; Female; Free Radical Scavengers; Gentisates; Glutathione; Homovanillic Acid; Hydroxybenzoates; Hydroxyl Radical; Male; Mice; Mice, Inbred BALB C; Monoamine Oxidase; MPTP Poisoning; Neostriatum; Neuroprotective Agents; Sodium Salicylate; Substantia Nigra | 2000 |
Dopaminergic denervation enhances susceptibility to hydroxyl radicals in rat neostriatum.
Topics: Animals; Carbidopa; Chromatography, High Pressure Liquid; Denervation; Dihydroxyphenylalanine; Dopamine; Female; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Neostriatum; Pregnancy; Rats; Salicylic Acid; Serotonin | 2000 |
Measurement of free radical production by in vivo microdialysis during ischemia/reperfusion injury to skeletal muscle.
Topics: Animals; Cytochrome c Group; Female; Free Radicals; Gentisates; Hydroxybenzoates; Microdialysis; Muscle, Skeletal; Rats; Rats, Wistar; Salicylic Acid; Superoxides | 2001 |
Non-steroidal anti-inflammatory drug sodium salicylate, but not diclofenac or celecoxib, protects against 1-methyl-4-phenyl pyridinium-induced dopaminergic neurotoxicity in rats.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Corpus Striatum; Diclofenac; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Gentisates; Hydroxybenzoates; Hydroxyl Radical; In Vitro Techniques; Male; Mortality; Neurodegenerative Diseases; Neuroprotective Agents; Pyrazoles; Rats; Rats, Inbred Strains; Rats, Sprague-Dawley; Sodium Salicylate; Sulfonamides | 2003 |
Postischemic hypothermia inhibits the generation of hydroxyl radical following transient forebrain ischemia in rats.
Topics: Animals; Brain; Brain Chemistry; Cerebrovascular Circulation; Corpus Striatum; Extracellular Space; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Hypothermia, Induced; Ischemic Attack, Transient; Male; Microdialysis; Rats; Rats, Wistar; Xanthine | 2003 |
Tempol, a novel stable nitroxide, reduces brain damage and free radical production, after acute subdural hematoma in the rat.
Topics: Animals; Antioxidants; Brain Chemistry; Brain Damage, Chronic; Cyclic N-Oxides; Disease Models, Animal; Drug Stability; Free Radicals; Gentisates; Hematoma, Subdural, Acute; Hydroxybenzoates; Male; Rats; Rats, Sprague-Dawley; Time Factors | 2003 |
Phospholipase A2, hydroxyl radicals, and lipid peroxidation in transient cerebral ischemia.
Topics: Animals; Arachidonic Acid; Calcium; Cardiolipins; Cell Membrane; Chromatography, High Pressure Liquid; Cytidine Diphosphate Choline; Gentisates; Gerbillinae; Hippocampus; Hydroxybenzoates; Hydroxyl Radical; Intracellular Membranes; Ischemic Attack, Transient; Lipid Peroxidation; Male; Malondialdehyde; Mitochondria; Models, Biological; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipases A; Phospholipases A2; Salicylic Acid | 2003 |
The role of superoxide dismutase and alpha-tocopherol in the development of seizures and kindling induced by pentylenetetrazol - influence of the radical scavenger alpha-phenyl-N-tert-butyl nitrone.
Topics: alpha-Tocopherol; Analysis of Variance; Animals; Blotting, Western; Chromatography, High Pressure Liquid; Convulsants; Cyclic N-Oxides; Disease Models, Animal; Drug Administration Schedule; Gentisates; Hydroxybenzoates; Kindling, Neurologic; Male; Neuroprotective Agents; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrogen Oxides; Pentylenetetrazole; Rats; Rats, Wistar; Seizures; Superoxide Dismutase; Time Factors | 2004 |
Isoflurane does not mimic ischaemic preconditioning in decreasing hydroxyl radical production in the rabbit.
Topics: Anesthetics, Inhalation; Animals; Gentisates; Hemodynamics; Hydroxybenzoates; Hydroxyl Radical; Ischemic Preconditioning, Myocardial; Isoflurane; Myocardial Infarction; Rabbits | 2005 |
Production of reactive oxygen species following acute ethanol or acetaldehyde and its reduction by acamprosate in chronically alcoholized rats.
Topics: Acamprosate; Acetaldehyde; Alcohol Deterrents; Alcoholism; Animals; Disease Models, Animal; Ethanol; Gentisates; Hippocampus; Hydroxybenzoates; Hydroxyl Radical; Male; Microdialysis; Rats; Rats, Wistar; Salicylic Acid; Substance Withdrawal Syndrome; Taurine; Time Factors | 2005 |
The salicylate trapping method: is oxidation of salicylic acid solution oxygen and time dependent and metal catalysed?
Topics: Aluminum; Catalysis; Catechols; Chromatography, Liquid; Gentisates; Hydroxybenzoates; Metals; Microdialysis; Oxidation-Reduction; Oxygen; Salicylic Acid; Time Factors | 2006 |
Edaravone reduces myocardial infarct size and improves cardiac function and remodelling in rabbits.
Topics: Animals; Antipyrine; Blood Pressure; Edaravone; Enzyme Inhibitors; Free Radical Scavengers; Gentisates; Heart Rate; Hydroxybenzoates; Myocardial Infarction; Myocardial Reperfusion Injury; NG-Nitroarginine Methyl Ester; Rabbits; Superoxides; Ventricular Remodeling | 2006 |
Hydroxyl radical generation dependent on extracellular ascorbate in rat striatum, as determined by microdialysis.
Topics: Animals; Ascorbic Acid; Behavior, Animal; Corpus Striatum; Dehydroascorbic Acid; Extracellular Space; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Male; Microdialysis; Rats; Rats, Sprague-Dawley | 2009 |
Acarbose reduces myocardial infarct size by preventing postprandial hyperglycemia and hydroxyl radical production and opening mitochondrial KATP channels in rabbits.
Topics: Acarbose; Animals; Blood Glucose; Catechols; Enzyme Inhibitors; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Hyperglycemia; Male; Myocardial Infarction; Potassium Channels; Rabbits | 2009 |
Hyperbaric oxygenation alleviates MCAO-induced brain injury and reduces hydroxyl radical formation and glutamate release.
Topics: Animals; Blood Pressure; Brain; Brain Injuries; Gentisates; Glutamates; Hydroxybenzoates; Hydroxyl Radical; Hyperbaric Oxygenation; Infarction, Middle Cerebral Artery; Male; Models, Animal; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 2010 |
Increased reactive oxygen species production in the brain after repeated low-dose pesticide paraquat exposure in rats. A comparison with peripheral tissues.
Topics: Animals; Brain; Catechols; Dopamine; Dose-Response Relationship, Drug; Gentisates; Herbicides; Hydroxybenzoates; Male; Microdialysis; Organ Specificity; Parabens; Paraquat; Rats; Rats, Wistar; Reactive Oxygen Species; Salicylic Acid | 2010 |
HPLC method for quantification of oxidative stress by salicilate hydroxylation in human plasma.
Topics: Biomarkers; Catechols; Chromatography, High Pressure Liquid; Drug Stability; Gentisates; Humans; Hydroxybenzoates; Hydroxylation; Linear Models; Oxidative Stress; Reproducibility of Results; Salicylates; Sensitivity and Specificity | 2010 |
Salicylic acid 3-hydroxylase regulates Arabidopsis leaf longevity by mediating salicylic acid catabolism.
Topics: Amino Acid Sequence; Arabidopsis; Arabidopsis Proteins; Biocatalysis; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Gentisates; Hydroxybenzoates; Kinetics; Mass Spectrometry; Mixed Function Oxygenases; Molecular Sequence Data; Molecular Structure; Mutation; Phylogeny; Plant Leaves; Plants, Genetically Modified; RNA, Messenger; Salicylic Acid; Sequence Homology, Amino Acid | 2013 |
Exploiting natural variation of secondary metabolism identifies a gene controlling the glycosylation diversity of dihydroxybenzoic acids in Arabidopsis thaliana.
Topics: Arabidopsis; Chromatography, High Pressure Liquid; Genes, Plant; Genetic Variation; Gentisates; Glycosides; Glycosylation; Hydrolysis; Hydroxybenzoates; Pentosyltransferases; Plant Leaves; Quantitative Trait Loci; Secondary Metabolism | 2014 |
Identification of a residue responsible for UDP-sugar donor selectivity of a dihydroxybenzoic acid glycosyltransferase from Arabidopsis natural accessions.
Topics: Arabidopsis; Arabidopsis Proteins; Gentisates; Glucuronosyltransferase; Hydroxybenzoates; Mutagenesis, Site-Directed; Polymorphism, Genetic; Structural Homology, Protein; Structure-Activity Relationship; Substrate Specificity | 2017 |
Holo-lipocalin-2-derived siderophores increase mitochondrial ROS and impair oxidative phosphorylation in rat cardiomyocytes.
Topics: Animals; Gentisates; Hydroxybenzoates; Iron; Lipocalin-2; Male; Mice; Mice, Knockout; Mitochondria; Myocytes, Cardiac; Oxidative Phosphorylation; Rats; Rats, Wistar; Reactive Oxygen Species; Reperfusion Injury; Siderophores | 2018 |
Modulation of Plant Salicylic Acid-Associated Immune Responses via Glycosylation of Dihydroxybenzoic Acids.
Topics: Arabidopsis; Disease Resistance; Gene Expression Regulation, Plant; Gentisates; Glycosylation; Glycosyltransferases; Homeostasis; Hydroxybenzoates; Plant Diseases; Plants, Genetically Modified; Pseudomonas syringae; Salicylic Acid | 2018 |
Choline Salicylate Analysis: Chemical Stability and Degradation Product Identification.
Topics: Choline; Chromatography, High Pressure Liquid; Drug Combinations; Drug Stability; Gentisates; Hydrolysis; Hydroxybenzoates; Molecular Structure; Photolysis; Salicylates; Tandem Mass Spectrometry | 2019 |
Benzoic acid derivatives as potent antibiofilm agents against Klebsiella pneumoniae biofilm.
Topics: Adhesins, Bacterial; Benzoic Acid; Biofilms; Humans; Klebsiella pneumoniae | 2023 |