Page last updated: 2024-08-18

2,5-diaminotoluene and 4-phenylenediamine

2,5-diaminotoluene has been researched along with 4-phenylenediamine in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (4.55)18.2507
2000's5 (22.73)29.6817
2010's16 (72.73)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chou, MW; Chung, KT; Huang, TS; Li, YS; Murdock, CA; Stevens, SE; Wei, CI1
Fautz, R; Fuchs, A; Henny, V; Smits, L; van der Walle, H1
Andersen, KE; Johansen, JD; Menné, T; Rastogi, SC; Søsted, H1
Bregnhøj, A; Menné, T1
Blömeke, B; Breuer, S; Coenraads, PJ; Grannemann, S; Merk, HF; Skazik, C; Wilbers, L1
Basketter, DA; English, J1
Biedermann, T; Caroli, U; Eichner, M; Fischer, J; Grimmel, C; Kneilling, M; Maier, FC; Röcken, M; Wieder, T1
Brand, P; Dewes, P; Gube, M; Heinrich, K; Kraus, T; Schettgen, T1
Gube, M; Heinrich, K; Kraus, T; Schettgen, T1
Boman, A; Lidén, C; Yazar, K1
Agner, T; Andersen, KE; Bruze, M; Diepgen, TL; Giménez-Arnau, AM; Gonçalo, M; Goossens, A; Johansen, JD; Le Coz, CJ; Maibach, H; Menné, T; Rustemeyer, T; Søsted, H; White, IR1
Hughes, TM; Ingram, JR; Stone, NM1
Pfuhler, S; Zeller, A1
Aalto-Korte, K; Airaksinen, L; Helaskoski, E; Kuuliala, O; Pesonen, M; Suojalehto, H; Virtanen, H1
Andersen, BL; Andersen, KE; Avnstorp, C; Danielsen, A; Funding, AT; Johansen, JD; Kristensen, B; Kristensen, O; Mortz, CG; Nielsen, NH; Osterballe, M; Paulsen, E; Schwensen, JF; Sommerlund, M; Søsted, H; Thormann, J; Thyssen, JP; Veien, NK; Vissing, S1
Hamann, CR; Hamann, D; Lidén, C; Thyssen, JP; Yazar, K1
Bruze, M; Svedman, C; Young, E; Zimerson, E1
Coenraads, PJ; Heijnen, RW; Schuttelaar, MA; Vogel, TA1
Antelmi, A; Bruze, M; Engfeldt, M; Foti, C; Persson, L; Sörensen, Ö; Svedman, C; Young, E; Zimerson, E1
Coenraads, PJ; Dijkstra, A; Prins, TM; Schuttelaar, MLA; Vogel, TA1
Blömeke, B; Diepgen, TL; Fuchs, A; Gaspari, AA; Goebel, C; Kimber, I; Krasteva, M; Schlotmann, K; Schnuch, A1
Ambrifi, M; Balato, N; Bufano, T; Cristaudo, A; Damiani, G; De Rocco, M; Diani, M; Foti, C; Napolitano, M; Patruno, C; Pigatto, P; Romita, P1

Trials

2 trial(s) available for 2,5-diaminotoluene and 4-phenylenediamine

ArticleYear
Para-phenylenediamine-specific lymphocyte activation test: a sensitive in vitro assay to detect para-phenylenediamine sensitization in patients with severe allergic reactions.
    Experimental dermatology, 2010, Volume: 19, Issue:5

    Topics: Adolescent; Adult; Azo Compounds; Cell Proliferation; Cross Reactions; Dermatitis, Allergic Contact; Female; Hair Dyes; Humans; Immunologic Tests; Interleukin-2; Leukocytes, Mononuclear; Lymphocyte Activation; Male; Patch Tests; Phenylenediamines; Sensitivity and Specificity; T-Lymphocytes; Young Adult

2010
Multicenter clinical trial on a permanent hair dye containing paratoluenediamine.
    Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia, 2018, Volume: 153, Issue:4

    Topics: Adult; Aged; Dermatitis, Allergic Contact; Female; Hair Dyes; Humans; Italy; Middle Aged; Patch Tests; Phenylenediamines; Young Adult

2018

Other Studies

20 other study(ies) available for 2,5-diaminotoluene and 4-phenylenediamine

ArticleYear
Mutagenicity and toxicity studies of p-phenylenediamine and its derivatives.
    Toxicology letters, 1995, Volume: 81, Issue:1

    Topics: Animals; Biotransformation; Carcinogens; CHO Cells; Chromosome Aberrations; Coloring Agents; Cricetinae; Dose-Response Relationship, Drug; Mutagenicity Tests; Phenylenediamines; Salmonella typhimurium; Structure-Activity Relationship

1995
Hair dye-sensitized hairdressers: the cross-reaction pattern with new generation hair dyes.
    Contact dermatitis, 2002, Volume: 46, Issue:6

    Topics: Allergens; Case-Control Studies; Cross Reactions; Dermatitis, Allergic Contact; Dermatitis, Occupational; Hair Dyes; Hand Dermatoses; Humans; Patch Tests; Phenylenediamines

2002
Hair dye contact allergy: quantitative exposure assessment of selected products and clinical cases.
    Contact dermatitis, 2004, Volume: 50, Issue:6

    Topics: Acute Disease; Aminophenols; Dermatitis, Allergic Contact; Hair Dyes; Humans; Phenylenediamines

2004
Primary sensitization to toluene-2,5-diamine giving rise to early positive patch reaction to p-phenylenediamine and late to toluene-2,5-diamine.
    Contact dermatitis, 2008, Volume: 59, Issue:3

    Topics: Administration, Topical; Allergens; Coloring Agents; Dermatitis, Allergic Contact; Facial Dermatoses; Female; Hair Dyes; Humans; Middle Aged; Patch Tests; Phenylenediamines

2008
Reactivity of in vitro activated human T lymphocytes to p-phenylenediamine and related substances.
    Contact dermatitis, 2008, Volume: 59, Issue:4

    Topics: Cell Line; Cell Proliferation; Clone Cells; Dermatitis, Allergic Contact; Drug Hypersensitivity; Drug Interactions; Humans; Hypersensitivity, Delayed; In Vitro Techniques; Lymphocyte Activation; p-Aminoazobenzene; Patch Tests; Phenylenediamines; T-Lymphocytes

2008
Cross-reactions among hair dye allergens.
    Cutaneous and ocular toxicology, 2009, Volume: 28, Issue:3

    Topics: Allergens; Cross Reactions; Hair Dyes; Humans; Hypersensitivity; Patch Tests; Phenylenediamines; Retrospective Studies

2009
Internal exposure of hairdressers to permanent hair dyes: a biomonitoring study using urinary aromatic diamines as biomarkers of exposure.
    International archives of occupational and environmental health, 2011, Volume: 84, Issue:3

    Topics: Adolescent; Adult; Biomarkers; Cohort Studies; Environmental Monitoring; Female; Gas Chromatography-Mass Spectrometry; Hair Dyes; Humans; Male; Middle Aged; Occupational Exposure; Phenylenediamines; Risk Assessment; Young Adult

2011
Determination of 2,5-toluylenediamine (2,5-TDA) and aromatic amines in urine after personal application of hair dyes: kinetics and doses.
    Archives of toxicology, 2011, Volume: 85, Issue:2

    Topics: Adult; Aminobiphenyl Compounds; Carcinogens; Diamines; Female; Gas Chromatography-Mass Spectrometry; Hair Dyes; Half-Life; Humans; Hydrocarbons, Aromatic; Isomerism; Limit of Detection; Phenylenediamines; Risk Assessment; Risk Factors; Skin Absorption; Toluidines; Urinary Bladder Neoplasms

2011
p-Phenylenediamine and other hair dye sensitizers in Spain.
    Contact dermatitis, 2012, Volume: 66, Issue:1

    Topics: Consumer Product Safety; Dermatitis, Allergic Contact; Dermatitis, Occupational; Hair Dyes; Humans; Phenylenediamines; Product Labeling; Spain; Sweden

2012
Contact allergy to common ingredients in hair dyes.
    Contact dermatitis, 2013, Volume: 69, Issue:1

    Topics: Administration, Topical; Adult; Coloring Agents; Denmark; Dermatitis, Allergic Contact; Female; Hair Dyes; Humans; Male; Patch Tests; Phenylenediamines; Prevalence; Risk Factors; Young Adult

2013
Potential danger of hair dyes marketed as free from para-phenylenediamine.
    International journal of dermatology, 2014, Volume: 53, Issue:4

    Topics: Aminophenols; Cross Reactions; Dermatitis, Allergic Contact; Hair Dyes; Humans; Marketing; Phenylenediamines; Product Labeling

2014
N-acetylation of three aromatic amine hair dye precursor molecules eliminates their genotoxic potential.
    Mutagenesis, 2014, Volume: 29, Issue:1

    Topics: Acetylation; Amines; Aniline Compounds; Animals; Cell Line, Transformed; Chromosome Aberrations; Comet Assay; Cresols; Female; Hair Dyes; Humans; Male; Micronucleus Tests; Molecular Structure; Mutagenicity Tests; Phenylenediamines; Rats; Salmonella typhimurium

2014
Occupational asthma, rhinitis, and contact urticaria caused by oxidative hair dyes in hairdressers.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2014, Volume: 112, Issue:1

    Topics: Adult; Anaphylaxis; Asthma, Occupational; Female; Hair Dyes; Humans; Male; Middle Aged; Occupational Exposure; Patch Tests; Phenylenediamines; Respiratory Function Tests; Rhinitis; Urticaria; Young Adult

2014
Occupational contact dermatitis in hairdressers: an analysis of patch test data from the Danish contact dermatitis group, 2002-2011.
    Contact dermatitis, 2014, Volume: 70, Issue:4

    Topics: Acetamides; Adolescent; Adult; Aged; Allergens; Aminophenols; Ammonium Sulfate; Barbering; Benzocaine; Coloring Agents; Cysteamine; Denmark; Dermatitis, Allergic Contact; Dermatitis, Occupational; Female; Hair Dyes; Humans; Male; Middle Aged; Patch Tests; Phenylenediamines; Thiram; Young Adult

2014
p-Phenylenediamine and other allergens in hair dye products in the United States: a consumer exposure study.
    Contact dermatitis, 2014, Volume: 70, Issue:4

    Topics: Allergens; Aminophenols; Barbering; Coloring Agents; Dermatitis, Allergic Contact; Environmental Exposure; Hair Dyes; Humans; Occupational Exposure; Phenylenediamines; Resorcinols; United States

2014
Two sensitizing oxidation products of p-phenylenediamine patch tested in patients allergic to p-phenylenediamine.
    Contact dermatitis, 2016, Volume: 74, Issue:2

    Topics: Dermatitis, Allergic Contact; Hair Dyes; Humans; Patch Tests; Phenylenediamines

2016
Two decades of p-phenylenediamine and toluene-2,5-diamine patch testing - focus on co-sensitizations in the European baseline series and cross-reactions with chemically related substances.
    Contact dermatitis, 2017, Volume: 76, Issue:2

    Topics: Adolescent; Adult; Aged; Child; Coloring Agents; Comorbidity; Cross Reactions; Dermatitis, Allergic Contact; Female; Hair Dyes; Humans; Male; Middle Aged; Patch Tests; Phenylenediamines; Young Adult

2017
Evaluation of concordance between labelling and content of 52 hair dye products: overview of the market of oxidative hair dye.
    European journal of dermatology : EJD, 2017, Apr-01, Volume: 27, Issue:2

    Topics: Chromatography, High Pressure Liquid; Consumer Product Safety; Europe; Hair Dyes; Phenylenediamines; Product Labeling

2017
The attitude of patients with p-phenylenediamine or 2,5-toluenediamine contact allergy to hair dyeing.
    Contact dermatitis, 2017, Volume: 76, Issue:6

    Topics: Beauty; Dermatitis, Allergic Contact; Hair Color; Hair Dyes; Health Knowledge, Attitudes, Practice; Humans; Personal Satisfaction; Phenylenediamines; Self Concept; Severity of Illness Index; Surveys and Questionnaires

2017
Skin sensitization quantitative risk assessment for occupational exposure of hairdressers to hair dye ingredients.
    Regulatory toxicology and pharmacology : RTP, 2018, Volume: 95

    Topics: Beauty Culture; Dermatitis, Allergic Contact; Female; Hair Dyes; Hand; Humans; Male; Occupational Exposure; Phenylenediamines; Risk Assessment; Skin Absorption

2018