2,4-pyridinedicarboxylic acid has been researched along with oxalylglycine in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (12.50) | 29.6817 |
| 2010's | 13 (81.25) | 24.3611 |
| 2020's | 1 (6.25) | 2.80 |
| Authors | Studies |
|---|---|
| Bello, SH; Liénard, BM; McDonough, MA; Mecinović, J; Ng, SS; Oppermann, U; Rose, NR; Schofield, CJ; Sun, Z | 1 |
| Flashman, E; Hindley, N; Liénard, BM; Loenarz, C; Mecinović, J; Schofield, CJ; Sobott, F; Stubbs, CJ; Yeoh, KK | 1 |
| Flamme, I; Hamada, S; Hasegawa, M; Itoh, Y; Kato, A; Komaarashi, H; Koseki, K; Mino, K; Miyata, N; Mizukami, T; Nakagawa, H; Oehme, F; Ogasawara, D; Ozasa, H; Sasaki, R; Suzuki, T; Tsumoto, H | 1 |
| Clifton, IJ; Conejo-Garcia, A; Ge, W; Hewitson, KS; Liénard, BM; Loenarz, C; McDonough, MA; McNeill, LA; Schofield, CJ | 1 |
| Agger, K; Clausen, RP; Gajhede, M; Helin, K; Kristensen, JL; Kristensen, LH; Lohse, B | 1 |
| Claridge, TD; Demetriades, M; Hardy, AP; Kawamura, A; Lejeune, C; Leung, IK; Schofield, CJ; Smart, TJ; Szöllössi, A | 1 |
| Aik, W; Bagg, EA; Demetriades, M; Hamdan, MK; Lejeune, C; McDonough, MA; Schofield, CJ; Yeoh, KK; Zhang, Z | 1 |
| Hasegawa, M; Itoh, Y; Kawamura, A; Mino, K; Miyata, N; Mizukami, T; Nakagawa, H; Ohkubo, R; Ozasa, H; Sasaki, R; Sawada, H; Schofield, CJ; Suzuki, T; Tsukada, Y; Tumber, A; Walport, L; Yonezawa, M; Zhan, P | 1 |
| Raines, RT; Vasta, JD | 1 |
| Brennan, PE; Burgess-Brown, NA; Che, K; Daniel, M; England, KS; Kawamura, A; Krojer, T; Ng, SS; Schofield, CJ; Scozzafava, G; Szykowska, A; Tumber, A; von Delft, F | 1 |
| Athanasou, N; Badock, V; Brennan, PE; Brown, J; Burgess-Brown, N; Egner, U; Gileadi, C; Hookway, ES; Johansson, C; Kopec, J; LaThangue, NB; Munro, S; Nowak, RP; Nuzzi, A; Oppermann, U; Philpott, M; Prinjha, R; Steuber, H; Strain-Damerell, C; Szykowska, A; Tumber, A; Velupillai, S; Westaway, S; Wu, N | 1 |
| Marholz, LJ; Wang, W; Wang, X; Zheng, Y | 1 |
| Abboud, MI; Langley, GW; Lohans, CT; Schofield, CJ | 1 |
| Andrijes, R; Ansari, MSZ; Antonini, L; Ciogli, A; Coleman, ML; Del Bufalo, D; Hendrix, E; Johansson, C; Kawamura, A; Mai, A; Mautone, N; Nowak, RP; Oppermann, U; Passeri, D; Pellegrini, FR; Pellicciari, R; Ragno, R; Rotili, D; Sabatino, M; Salah, E; Schofield, CJ; Simelis, K; Trisciuoglio, D; Tumber, A | 1 |
| Burckhardt, BC; Burckhardt, G; Hagos, Y; Krick, W; Schley, G; Schödel, J; Willam, C | 1 |
| Amann, K; Beyer, A; Burckhardt, BC; Burzlaff, N; Eckardt, KU; Hagos, Y; Klanke, B; Kröning, S; Schley, G; Schödel, J; Türkoglu, G; Willam, C | 1 |
1 review(s) available for 2,4-pyridinedicarboxylic acid and oxalylglycine
| Article | Year |
|---|---|
Inhibitors of histone demethylases.
Topics: Animals; Binding Sites; Enzyme Activation; Enzyme Inhibitors; Histone Demethylases; Humans; Methylation; Models, Molecular; Molecular Structure; Substrate Specificity | 2011 |
15 other study(ies) available for 2,4-pyridinedicarboxylic acid and oxalylglycine
| Article | Year |
|---|---|
Inhibitor scaffolds for 2-oxoglutarate-dependent histone lysine demethylases.
Topics: Crystallography, X-Ray; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Ketoglutaric Acids; Models, Molecular; Molecular Structure; Oxidoreductases, N-Demethylating; Protein Structure, Tertiary; Stereoisomerism; Structure-Activity Relationship | 2008 |
Application of a proteolysis/mass spectrometry method for investigating the effects of inhibitors on hydroxylase structure.
Topics: Animals; Catalytic Domain; Enzyme Inhibitors; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Inhibitory Concentration 50; Mixed Function Oxygenases; Models, Molecular; Peptide Fragments; Protein Stability; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2009 |
Design, synthesis, enzyme-inhibitory activity, and effect on human cancer cells of a novel series of jumonji domain-containing protein 2 histone demethylase inhibitors.
Topics: Amino Acids, Dicarboxylic; Antineoplastic Agents; beta-Alanine; Catalytic Domain; Cell Line, Tumor; Drug Screening Assays, Antitumor; Drug Synergism; Histone Demethylases; Humans; Hydroxamic Acids; Jumonji Domain-Containing Histone Demethylases; Models, Molecular; Molecular Structure; Prodrugs; Structure-Activity Relationship | 2010 |
Structural basis for binding of cyclic 2-oxoglutarate analogues to factor-inhibiting hypoxia-inducible factor.
Topics: Binding Sites; Catalytic Domain; Humans; Ketoglutaric Acids; Mixed Function Oxygenases; Models, Molecular; Protein Binding; Repressor Proteins | 2010 |
Reporter ligand NMR screening method for 2-oxoglutarate oxygenase inhibitors.
Topics: Citric Acid Cycle; Enzyme Inhibitors; Humans; Ketoglutaric Acids; Ligands; Magnetic Resonance Spectroscopy; Oxygenases | 2013 |
Structural basis for inhibition of the fat mass and obesity associated protein (FTO).
Topics: Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Binding Sites; Drug Discovery; Humans; Models, Molecular; Protein Conformation; Proteins; Substrate Specificity | 2013 |
Identification of the KDM2/7 histone lysine demethylase subfamily inhibitor and its antiproliferative activity.
Topics: Antineoplastic Agents; Catalytic Domain; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Histone Demethylases; Humans; Inhibitory Concentration 50; Models, Molecular | 2013 |
Selective inhibition of prolyl 4-hydroxylases by bipyridinedicarboxylates.
Topics: Animals; Binding, Competitive; Carboxylic Acids; Collagen; Dose-Response Relationship, Drug; Enzyme Assays; Humans; Hypoxia-Inducible Factor-Proline Dioxygenases; Iron; Iron Chelating Agents; Isoenzymes; Kinetics; Procollagen-Proline Dioxygenase; Prolyl-Hydroxylase Inhibitors; Pyridines; Recombinant Proteins | 2015 |
Optimisation of a triazolopyridine based histone demethylase inhibitor yields a potent and selective KDM2A (FBXL11) inhibitor.
Topics: | 2014 |
Structural analysis of human KDM5B guides histone demethylase inhibitor development.
Topics: Antineoplastic Agents; Cell Proliferation; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Histone Demethylases; Humans; Jumonji Domain-Containing Histone Demethylases; Models, Molecular; Multiple Myeloma; Nuclear Proteins; Protein Conformation; Repressor Proteins; Structure-Activity Relationship | 2016 |
A Fluorescence Polarization Biophysical Assay for the Naegleria DNA Hydroxylase Tet1.
Topics: | 2016 |
Inhibition of a viral prolyl hydroxylase.
Topics: Enzyme Assays; Hydroxylation; Hypoxia-Inducible Factor-Proline Dioxygenases; Ketoglutaric Acids; Oligopeptides; Phycodnaviridae; Procollagen-Proline Dioxygenase; Prolyl-Hydroxylase Inhibitors; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2019 |
First-in-Class Inhibitors of the Ribosomal Oxygenase MINA53.
Topics: Cell Line, Tumor; Cell Proliferation; Crystallization; Dioxygenases; Enzyme Inhibitors; Histone Demethylases; Humans; Models, Molecular; Nuclear Proteins; Protein Conformation; Ribosomes; Substrate Specificity | 2021 |
α-Ketoglutarate-related inhibitors of HIF prolyl hydroxylases are substrates of renal organic anion transporters 1 (OAT1) and 4 (OAT4).
Topics: Amino Acids, Dicarboxylic; Biological Transport, Active; Dioxygenases; Estrone; HEK293 Cells; Humans; Hypoxia-Inducible Factor 1; Ketoglutaric Acids; Organic Anion Transport Protein 1; Organic Anion Transporters; Organic Anion Transporters, Sodium-Dependent; p-Aminohippuric Acid; Procollagen-Proline Dioxygenase; Pyridines; Succinic Acid; Symporters | 2012 |
Selective stabilization of HIF-1α in renal tubular cells by 2-oxoglutarate analogues.
Topics: Acetic Acid; Acute Kidney Injury; Amino Acids, Dicarboxylic; Animals; Biological Transport; Cell Line; Cell Separation; Gene Expression Regulation; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Ischemia; Ischemic Preconditioning; Ketoglutaric Acids; Kidney Function Tests; Kidney Tubules, Proximal; Mice; Organic Anion Transport Protein 1; Protein Stability; Pyridines | 2012 |