2-4-dinitrophenylhydrazine and methylmalondialdehyde

2-4-dinitrophenylhydrazine has been researched along with methylmalondialdehyde* in 1 studies

Other Studies

1 other study(ies) available for 2-4-dinitrophenylhydrazine and methylmalondialdehyde

ArticleYear
Methyl malondialdehyde is not suitable as an internal standard for malondialdehyde detection in urine after derivatisation with 2,4-dinitrophenylhydrazine.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2004, Jul-05, Volume: 806, Issue:2

    A previously described method of measurement of malondialdehyde (MDA) in human urine after derivatisation with 2,4-dinitrophenylhydrazine (DNPH) was tested for a possibility of using methyl malondialdehyde (MeMDA) as an internal standard. Despite structural similarity, those compounds were found to produce different yields of derivatisation under the same conditions depending on urine matrix. We conclude, that MeMDA is not suitable as an internal standard for the measurement of MDA in urine under previously reported conditions when DNPH is used as a deriviatising agent.

    Topics: Calibration; Chromatography, High Pressure Liquid; Humans; Indicators and Reagents; Malondialdehyde; Phenylhydrazines; Reference Standards; Spectrophotometry, Ultraviolet

2004