2-4-dinitrophenylhydrazine and chloroacetaldehyde

2-4-dinitrophenylhydrazine has been researched along with chloroacetaldehyde* in 1 studies

Other Studies

1 other study(ies) available for 2-4-dinitrophenylhydrazine and chloroacetaldehyde

Article	Year
2-Chloroacetaldehyde, a metabolite of cyclophosphamide in the rat. Xenobiotica; the fate of foreign compounds in biological systems, 1983, Volume: 13, Issue:7 Following simultaneous i.v. administration of a mixture of [4-14C]cyclophosphamide (14C-CP) and [side-chain 3H]CP to rats, a metabolite containing predominantly 3H radioactivity was excreted in the urine. The 3H-labelled urinary metabolite was identified as 2-chloroacetaldehyde. Chloro[3H]acetaldehyde accounted for approx. 3.8% of urinary 3H radioactivity. The importance of chloroacetaldehyde as a toxic metabolite of CP is discussed, particularly in relation to haemorrhagic bladder disease. Topics: Acetaldehyde; Animals; Carbon Radioisotopes; Chromatography, Thin Layer; Cyclophosphamide; Male; Phenylhydrazines; Rats; Rats, Inbred Strains; Spectrophotometry; Tritium	1983

Article

Year

2-Chloroacetaldehyde, a metabolite of cyclophosphamide in the rat.

Xenobiotica; the fate of foreign compounds in biological systems, 1983, Volume: 13, Issue:7

Following simultaneous i.v. administration of a mixture of [4-14C]cyclophosphamide (14C-CP) and [side-chain 3H]CP to rats, a metabolite containing predominantly 3H radioactivity was excreted in the urine. The 3H-labelled urinary metabolite was identified as 2-chloroacetaldehyde. Chloro[3H]acetaldehyde accounted for approx. 3.8% of urinary 3H radioactivity. The importance of chloroacetaldehyde as a toxic metabolite of CP is discussed, particularly in relation to haemorrhagic bladder disease.

Topics: Acetaldehyde; Animals; Carbon Radioisotopes; Chromatography, Thin Layer; Cyclophosphamide; Male; Phenylhydrazines; Rats; Rats, Inbred Strains; Spectrophotometry; Tritium

1983