2,4-dichloro-5-sulfamoylbenzoic acid has been researched along with acetazolamide in 4 studies
*Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337) [MeSH]
*Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337) [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Grüneberg, S; Klebe, G; Stubbs, MT | 1 |
| Bülbül, M; Büyükgüngör, O; Celik, H; Ilkimen, H; Sari, M; Yenikaya, C | 1 |
| Bülbül, M; Büyükgüngör, O; Cinar, B; Ilkimen, H; Sari, M; Yenikaya, C | 1 |
| Čapkauskaitė, E; Dvinskis, E; Gražulis, S; Jezepčikas, L; Kazaks, A; Leitans, J; Linkuvienė, V; Manakova, E; Matulis, D; Paketurytė, V; Smirnov, A; Tars, K; Zakšauskas, A | 1 |
4 other study(ies) available for 2,4-dichloro-5-sulfamoylbenzoic acid and acetazolamide
| Article | Year |
|---|---|
Successful virtual screening for novel inhibitors of human carbonic anhydrase: strategy and experimental confirmation.
Topics: Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Crystallography, X-Ray; Databases, Factual; Humans; Isoenzymes; Ligands; Models, Molecular; Protein Binding; Quantitative Structure-Activity Relationship | 2002 |
Synthesis, characterization and antiglaucoma activity of a novel proton transfer compound and a mixed-ligand Zn(II) complex.
Topics: Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Crystallography, X-Ray; Erythrocytes; Glaucoma; Humans; Ligands; Magnetic Resonance Spectroscopy; Models, Molecular; Organometallic Compounds; Protons; Spectroscopy, Fourier Transform Infrared; Structure-Activity Relationship; Temperature; Zinc | 2010 |
Synthesis and characterisation of two novel proton transfer compounds and their inhibition studies on carbonic anhydrase isoenzymes.
Topics: Acetazolamide; Aminopyridines; Animals; Benzoates; Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Crystallography, X-Ray; Enzyme Assays; Erythrocytes; Ethylenediamines; Glaucoma; Humans; Inhibitory Concentration 50; Isoenzymes; Kinetics; Mice; Picolines; Protons; Spectrum Analysis | 2011 |
Halogenated and di-substituted benzenesulfonamides as selective inhibitors of carbonic anhydrase isoforms.
Topics: Benzenesulfonamides; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Crystallography, X-Ray; Dose-Response Relationship, Drug; Halogenation; Humans; Isoenzymes; Models, Molecular; Molecular Structure; Structure-Activity Relationship; Sulfonamides | 2020 |