2,4-diaminotoluene has been researched along with 2,6-diaminotoluene in 39 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (12.82) | 18.7374 |
| 1990's | 22 (56.41) | 18.2507 |
| 2000's | 8 (20.51) | 29.6817 |
| 2010's | 4 (10.26) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Friedman, MA; Unger, PD | 1 |
| Armstrong, MJ; Bean, CL; Galloway, SM | 2 |
| Brorson, T; Sangö, C; Skarping, G | 2 |
| Alipui, C; Demick, D; McMahon, KK; Ramos, KS | 1 |
| George, E; Westmoreland, C | 1 |
| Siciliano, AA; Szycher, M | 1 |
| Boorman, GA; Dieter, MP; Huff, JE; Jameson, CW; Matthews, HB | 1 |
| Cunningham, ML; Foley, J; Maronpot, RR; Matthews, HB | 1 |
| Fukui, S; Fukunaga, Y; Hirayama, T; Ono, M; Watanabe, T | 1 |
| Stephan, U; Weisbrod, D | 1 |
| Friedman, MA; Greene, EJ; Salerno, AJ | 1 |
| Cunningham, ML; Hayward, JJ; Shane, BS; Tindall, KR | 2 |
| Czech, S; Eckert, P; Henschler, D; Sabbioni, G; Sepai, O | 1 |
| Columbano, A; Ledda-Columbano, GM; Parodi, S; Peluso, M; Taningher, M | 1 |
| Benoit, FM | 1 |
| Amin, P; Kydonieus, A; Shah, K; Wille, J | 1 |
| Cunningham, ML; Matthews, HB | 1 |
| Cheung, YL; Gray, TJ; Ioannides, C; Mohammed, NN; Snelling, J | 1 |
| Dalene, M; Hagmar, L; Lind, P; Skarping, G | 1 |
| Froines, JR; La, DK; Wilson, PM | 1 |
| Dalene, M; Lind, P; Skarping, G; Tinnerberg, H | 1 |
| Günzel, P; Reimann, R | 1 |
| Brennan, RJ; Schiestl, RH | 1 |
| Hirvonen, A; Kääriä, K; Norppa, H; Piirilä, P; Rosenberg, C; Vainio, H | 1 |
| Kim, Y; Morita, Y; Sakai, T; Tao, YX | 1 |
| Nikel, G; Pecka, I; Sitko, E; Wiglusz, R | 1 |
| Kim, H; Kim, Y; Morita, Y; Roh, J; Sakai, T | 1 |
| Beck, BD; Hayes, AW; Lewandowski, TA | 1 |
| Beevers, C; Kirkland, D | 1 |
| Austin, S | 1 |
| Bruce, SW; Leung, C; Pant, K; San, RH; Sly, JE | 1 |
| Hayashi, H; Inoue, T; Kawamura, Y; Kurata, Y; Masumura, K; Nishikawa, A; Nohmi, T; Sanada, H; Takamune, M; Toyoda-Hokaiwado, N; Umemura, T; Yamada, M | 1 |
| Matsumoto, H; Saito, F; Takeyoshi, M | 1 |
| Abe, Y; Akiyama, H; Kawamura, Y; Mutsuga, M; Yamaguchi, M | 1 |
| Jeżewska, A; Kowalska, J | 1 |
1 review(s) available for 2,4-diaminotoluene and 2,6-diaminotoluene
| Article | Year |
|---|---|
Cell proliferation as a determining factor for the carcinogenicity of chemicals: studies with mutagenic carcinogens and mutagenic noncarcinogens.
Topics: Animals; Carcinogens; Cell Division; Humans; Mice; Mutagens; Phenylenediamines | 1995 |
38 other study(ies) available for 2,4-diaminotoluene and 2,6-diaminotoluene
| Article | Year |
|---|---|
High-performance liquid chromatography of 2,6- and 2,4-diaminotoluene, and its application to the determination of 2,4-diaminotoluene in urine and plasma.
Topics: Animals; Chromatography, High Pressure Liquid; Isomerism; Methods; Microchemistry; Phenylenediamines; Rats | 1979 |
Effect of sampling time on chromosome aberration yield for 7 chemicals in Chinese hamster ovary cells.
Topics: Aminobiphenyl Compounds; Animals; Cadmium; Cadmium Compounds; Cell Count; CHO Cells; Chromosome Aberrations; Cricetinae; Cytarabine; Doxorubicin; Eugenol; Mutagenicity Tests; Mutagens; Phenylenediamines; Sulfates; Time Factors | 1992 |
A quantitative assessment of the cytotoxicity associated with chromosomal aberration detection in Chinese hamster ovary cells.
Topics: Aminobiphenyl Compounds; Animals; Cadmium; Cadmium Compounds; CHO Cells; Chromosome Aberrations; Cricetinae; Doxorubicin; Eugenol; Evaluation Studies as Topic; Mitomycin; Mutagenicity Tests; Mutagens; Oxyquinoline; Phenylenediamines; Sulfates; Time Factors | 1992 |
Biological monitoring of isocyanates and related amines. III. Test chamber exposure of humans to toluene diisocyanate.
Topics: Adult; Air Pollutants, Occupational; Chromatography, High Pressure Liquid; Environmental Monitoring; Gas Chromatography-Mass Spectrometry; Humans; Male; Maximum Allowable Concentration; Metabolic Clearance Rate; Middle Aged; Occupational Exposure; Phenylenediamines; Risk Factors; Toluene 2,4-Diisocyanate | 1991 |
Biological monitoring of isocyanates and related amines. IV. 2,4- and 2,6-toluenediamine in hydrolysed plasma and urine after test-chamber exposure of humans to 2,4- and 2,6-toluene diisocyanate.
Topics: Adult; Air Pollutants; Environmental Monitoring; Humans; Male; Phenylenediamines; Toluene 2,4-Diisocyanate | 1991 |
Modulation of DNA synthesis in aortic smooth muscle cells by dinitrotoluenes.
Topics: Animals; Aorta, Thoracic; Arteriosclerosis; Cells, Cultured; Dinitrobenzenes; DNA; Male; Muscle, Smooth, Vascular; Phenylenediamines; Rats; Rats, Inbred Strains; Staining and Labeling; Thymidine | 1991 |
Evaluation of the in vivo genotoxicity of the structural analogues 2,6-diaminotoluene and 2,4-diaminotoluene using the rat micronucleus test and rat liver UDS assay.
Topics: Animals; Bone Marrow; Carcinogenicity Tests; DNA; Female; Liver; Male; Micronucleus Tests; Phenylenediamines; Rats; Rats, Inbred F344; Rats, Inbred Strains | 1991 |
An assessment of 2,4 TDA formation from Surgitek polyurethane foam under simulated physiological conditions.
Topics: Animals; Biocompatible Materials; Biodegradation, Environmental; Female; Humans; Isomerism; Models, Biological; Phenylenediamines; Polyurethanes; Prostheses and Implants | 1991 |
The carcinogenic activity of commercial grade toluene diisocyanate in rats and mice in relation to the metabolism of the 2,4- and 2,6-TDI isomers.
Topics: Animals; Body Weight; Carcinogens; Dose-Response Relationship, Drug; Female; Male; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Phenylenediamines; Rats; Rats, Inbred Strains; Survival Analysis; Toluene 2,4-Diisocyanate | 1990 |
Correlation of hepatocellular proliferation with hepatocarcinogenicity induced by the mutagenic noncarcinogen:carcinogen pair--2,6- and 2,4-diaminotoluene.
Topics: Animals; Carcinogens; Cell Division; Dose-Response Relationship, Drug; Liver; Liver Neoplasms, Experimental; Male; Mutagens; Phenylenediamines; Rats; Rats, Inbred F344 | 1991 |
7-Amino-2,4,6-trimethylquinoline as a mutagenic pyrolysate compound of polyurethane foam.
Topics: Aminoquinolines; Biotransformation; Chemical Phenomena; Chemistry; Chromatography; Construction Materials; Hot Temperature; Mutagenicity Tests; Mutagens; Phenylenediamines; Polyurethanes; Salmonella typhimurium | 1989 |
Toluene diisocyanate.
Topics: Air Pollution; Animals; Chemical Phenomena; Chemistry; Cyanates; Environmental Exposure; Humans; Lethal Dose 50; Mice; Mutagenicity Tests; Phenylenediamines; Polyurethanes; Rats; Rats, Inbred F344; Rubber; Toluene 2,4-Diisocyanate | 1986 |
[Toxic, methemoglobin producing and erythrocyte damaging effects of diaminotoluene following a single application].
Topics: Animals; Erythrocytes; Heinz Bodies; Lethal Dose 50; Male; Methemoglobin; Mice; Mice, Inbred ICR; Phenylenediamines; Rats; Rats, Inbred Strains | 1983 |
Effect of 4 toluene diamine isomers on murine testicular DNA synthesis.
Topics: Animals; DNA; Dose-Response Relationship, Drug; Male; Mice; Mutagenicity Tests; Mutagens; Phenylenediamines; Testis | 1981 |
Differential in vivo mutagenicity of the carcinogen/non-carcinogen pair 2,4- and 2,6-diaminotoluene.
Topics: Animals; Bacterial Proteins; Bacteriophage lambda; Biotransformation; Carcinogens; Dimethylnitrosamine; DNA; Escherichia coli; Escherichia coli Proteins; Genes, Bacterial; Lac Repressors; Male; Mice; Mice, Inbred Strains; Mice, Transgenic; Microsomes, Liver; Mutagenicity Tests; Mutagens; Neoplasms, Experimental; Phenylenediamines; Rats; Repressor Proteins; Salmonella typhimurium; Virus Integration | 1995 |
Exposure to toluenediamines from polyurethane-covered breast implants.
Topics: Breast Implants; Breast Neoplasms; Female; Gas Chromatography-Mass Spectrometry; Humans; Phenylenediamines; Polyurethanes | 1995 |
Genotoxic and non-genotoxic activities of 2,4- and 2,6-diaminotoluene, as evaluated in Fischer-344 rat liver.
Topics: Animals; Body Weight; Carcinogenicity Tests; Carcinogens; DNA Adducts; Liver; Liver Neoplasms, Experimental; Mutagenicity Tests; Mutagens; Organ Size; Phenylenediamines; Precancerous Conditions; Rats; Rats, Inbred F344 | 1995 |
Degradation of polyurethane foams used in the Même breast implant.
Topics: Biocompatible Materials; Drug Contamination; Female; Humans; Mammaplasty; Phenylenediamines; Polyurethanes; Prostheses and Implants; Toluene 2,4-Diisocyanate | 1993 |
Analysis of the extractive and hydrolytic behavior of microthane poly(ester-urethane) foam by high pressure liquid chromatography.
Topics: Biocompatible Materials; Buffers; Chromatography, High Pressure Liquid; Hydrogen-Ion Concentration; Hydrolysis; Indicators and Reagents; Phenylenediamines; Polyesters; Polyurethanes; Spectrophotometry, Ultraviolet | 1993 |
Interaction with the aromatic hydrocarbon receptor, CYP1A induction, and mutagenicity of a series of diaminotoluenes: implications for their carcinogenicity.
Topics: Animals; Aroclors; Binding Sites; Carcinogens; Chlorodiphenyl (54% Chlorine); Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Male; Mutagens; Mutation; Oxidoreductases; Phenylenediamines; Rats; Rats, Wistar; Receptors, Aryl Hydrocarbon; Stereoisomerism | 1996 |
Toxicokinetics of 2,4- and 2,6-toluenediamine in hydrolysed urine and plasma after occupational exposure to 2,4- and 2,6- toluene diisocyanate.
Topics: Air Pollution; Gas Chromatography-Mass Spectrometry; Half-Life; Humans; Hydrolysis; Isomerism; Occupational Exposure; Phenylenediamines; Toluene 2,4-Diisocyanate | 1996 |
Distinction of mutagenic carcinogens from a mutagenic noncarcinogen in the big blue transgenic mouse.
Topics: Animals; Bacterial Proteins; Carcinogens; Diet; Escherichia coli Proteins; Lac Repressors; Liver; Male; Mice; Mice, Transgenic; Mutagenicity Tests; Mutagens; Phenylenediamines; Repressor Proteins; Time Factors | 1996 |
Hemoglobin and DNA adduct formation in Fischer-344 rats exposed to 2,4- and 2,6-toluene diamine.
Topics: Animals; Carcinogens; DNA Adducts; Hemoglobins; Male; Phenylenediamines; Rats; Rats, Inbred F344 | 1996 |
Biomarkers in hydrolysed urine, plasma and erythrocytes among workers exposed to thermal degradation products from toluene diisocyanate foam.
Topics: Biomarkers; Carcinogens; Chemical Industry; Erythrocytes; Gas Chromatography-Mass Spectrometry; Half-Life; Hot Temperature; Humans; Mutagens; Occupational Exposure; Phenylenediamines; Polyurethanes; Toluene 2,4-Diisocyanate | 1997 |
Mutagenic carcinogens and noncarcinogens in transgenic mice.
Topics: Animals; Carcinogens; Male; Mice; Mice, Transgenic; Mutagenicity Tests; Mutagens; Phenylenediamines | 1997 |
Diaminotoluenes induce intrachromosomal recombination and free radicals in Saccharomyces cerevisiae.
Topics: Acetylcysteine; Animals; Biotransformation; Carcinogens; DNA, Fungal; Free Radical Scavengers; Free Radicals; Microsomes, Liver; Mutagenicity Tests; Mutagens; Phenylenediamines; Rats; Recombination, Genetic; Saccharomyces cerevisiae; Sequence Deletion; Structure-Activity Relationship | 1997 |
Exposure to 2,4- and 2,6-toluene diisocyanate (TDI) during production of flexible foam: determination of airborne TDI and urinary 2,4- and 2,6-toluenediamine (TDA).
Topics: Adult; Air Pollutants, Occupational; Chemical Industry; Chromatography, High Pressure Liquid; Environmental Monitoring; Female; Gas Chromatography-Mass Spectrometry; Humans; Male; Middle Aged; Occupational Exposure; Phenylenediamines; Toluene 2,4-Diisocyanate | 2001 |
LC-MS determination of urinary toluenediamine in workers exposed to toluenediisocyanate.
Topics: Chromatography, Liquid; Environmental Monitoring; Humans; Inhalation Exposure; Mass Spectrometry; Occupational Exposure; Phenylenediamines; Toluene 2,4-Diisocyanate | 2002 |
[Assessment of the emission of volatile organic compounds from polyurethane foams].
Topics: Air Pollutants; Air Pollution, Indoor; Carcinogens; Construction Materials; Ethanolamines; Humans; Organic Chemicals; Phenylenediamines; Piperazines; Poland; Polyurethanes; Volatilization | 2004 |
Improvement in the GC-MS method for determining urinary toluene-diamine and its application to the biological monitoring of workers exposed to toluene-diisocyanate.
Topics: Air Pollutants, Occupational; Biomarkers; Creatinine; Gas Chromatography-Mass Spectrometry; Humans; Male; Occupational Exposure; Phenylenediamines; Specific Gravity; Toluene 2,4-Diisocyanate | 2005 |
Risk evaluation of occupational exposure to methylene dianiline and toluene diamine in polyurethane foam.
Topics: Aniline Compounds; Chemical Industry; Environmental Monitoring; Humans; Occupational Exposure; Phenylenediamines; Polyurethanes; Risk Assessment; Skin Absorption | 2005 |
Induction of LacZ mutations in Muta Mouse can distinguish carcinogenic from non-carcinogenic analogues of diaminotoluenes and nitronaphthalenes.
Topics: Animals; Carcinogenicity Tests; Carcinogens; Kidney; Lac Operon; Liver; Male; Mice; Mice, Transgenic; Models, Animal; Mutagens; Mutation; Naphthalenes; Phenylenediamines; Skin; Urinary Bladder | 2006 |
Biological monitoring of TDI-derived amines in polyurethane foam production.
Topics: Adult; Biomarkers; Environmental Monitoring; Female; Humans; Male; Middle Aged; Occupational Exposure; Phenylenediamines; Polyurethanes; Skin Absorption | 2007 |
Syrian hamster embryo (SHE) cell transformation assay with conditioned media (without X-ray irradiated feeder layer) using 2,4-diaminotoluene, 2,6-diaminotoluene and chloral hydrate.
Topics: Animals; Carcinogenicity Tests; Cell Culture Techniques; Cell Transformation, Neoplastic; Chloral Hydrate; Cricetinae; Culture Media, Conditioned; Embryo, Mammalian; Mesocricetus; Phenylenediamines; X-Rays | 2008 |
Integration of in vivo genotoxicity and short-term carcinogenicity assays using F344 gpt delta transgenic rats: in vivo mutagenicity of 2,4-diaminotoluene and 2,6-diaminotoluene structural isomers.
Topics: Animals; Carcinogenicity Tests; Escherichia coli Proteins; Liver; Male; Mutagenicity Tests; Mutagens; Pentosyltransferases; Phenylenediamines; Rats; Rats, Inbred F344; Rats, Transgenic | 2010 |
Applicability of a gene expression based prediction method to SD and Wistar rats: an example of CARCINOscreen®.
Topics: Administration, Oral; Animals; Carcinogenicity Tests; Carcinogens; Gene Expression; Liver; Male; Microarray Analysis; Phenylenediamines; Predictive Value of Tests; Rats, Sprague-Dawley; Rats, Wistar; RNA; Sodium Benzoate; Thioacetamide | 2015 |
Survey of Primary Aromatic Amines and Colorants in Polyurethane, Nylon and Textile Toys.
Topics: Amines; Aniline Compounds; Chromatography, Liquid; Coloring Agents; Nylons; Phenylenediamines; Play and Playthings; Polyurethanes; Tandem Mass Spectrometry; Textiles | 2016 |
[A new method for determination of toluene-2,4-diamine and toluene-2,6-diamine in workplace air].
Topics: Air Pollutants, Occupational; Chromatography, Liquid; Limit of Detection; Phenylenediamines | 2017 |