2,4-diaminoquinazoline has been researched along with methotrexate in 6 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (66.67) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bowden, K; Harris, NV; Smith, C | 1 |
| Crippen, GM; Ghose, AK | 1 |
| Freisheim, JH; Hynes, JB; Kumar, A; Susten, SS | 1 |
| Cheng, CC; Roth, B | 1 |
| McCormack, JJ | 1 |
| Beverley, SM; Hardy, LW; Matthews, W; Nare, B | 1 |
2 review(s) available for 2,4-diaminoquinazoline and methotrexate
| Article | Year |
|---|---|
Recent progress in the medicinal chemistry of 2,4-diaminopyrimidines.
Topics: Amino Acid Sequence; Animals; Folic Acid Antagonists; Glutamates; Glutamic Acid; Malaria; Mathematics; Methotrexate; Microbial Sensitivity Tests; Models, Chemical; Pyrimethamine; Pyrimidines; Quinazolines; Stereoisomerism; Triazines | 1982 |
Dihydrofolate reductase inhibitors as potential drugs.
Topics: Aminopterin; Animals; Antimalarials; Bacterial Infections; Biological Transport; Drug Interactions; Folic Acid; Folic Acid Antagonists; Helminthiasis; Humans; Immunosuppressive Agents; Leukemia, Experimental; Liver; Methotrexate; Mice; Mycoses; Neoplasms; Protozoan Infections; Psoriasis; Quinazolines; Rats; Receptors, Drug; Trypanosoma cruzi | 1981 |
4 other study(ies) available for 2,4-diaminoquinazoline and methotrexate
| Article | Year |
|---|---|
Antifolate and antibacterial activities of 5-substituted 2,4-diaminoquinazolines.
Topics: Animals; Anti-Bacterial Agents; Cattle; Chemical Phenomena; Chemistry; Escherichia coli; Escherichia coli Infections; Folic Acid Antagonists; Liver; Mice; Molecular Structure; Quinazolines; Staphylococcus aureus; Structure-Activity Relationship | 1990 |
Combined distance geometry analysis of dihydrofolate reductase inhibition by quinazolines and triazines.
Topics: Chemical Phenomena; Chemistry; Folic Acid Antagonists; Molecular Conformation; Quinazolines; Streptococcus; Structure-Activity Relationship; Triazines | 1983 |
Inhibition of dihydrofolate reductase, methotrexate transport, and growth of methotrexate-sensitive and -resistant L1210 leukemia cells in vitro by 5-substituted 2,4-diaminoquinazolines.
Topics: Animals; Biological Transport; Cells, Cultured; Drug Resistance; Folic Acid Antagonists; Leukemia L1210; Methotrexate; Mice; Quinazolines; Structure-Activity Relationship | 1985 |
Biochemical and genetic tests for inhibitors of Leishmania pteridine pathways.
Topics: Animals; Cell Division; Drug Resistance; Folic Acid Antagonists; Humans; Leishmania; Methotrexate; Microbial Sensitivity Tests; Multienzyme Complexes; Mutation; Oxidoreductases; Pteridines; Pyrimidines; Quinazolines; Species Specificity; Tetrahydrofolate Dehydrogenase; Thymidylate Synthase | 1997 |