2,4-diaminopyridine has been researched along with 4-aminopyridine in 19 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (52.63) | 18.7374 |
| 1990's | 2 (10.53) | 18.2507 |
| 2000's | 5 (26.32) | 29.6817 |
| 2010's | 2 (10.53) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rauckman, BS; Roth, B | 1 |
| Cook, L; DeNoble, KF; DeNoble, VJ; Johnson, LC; Myers, MJ; Scribner, RM; Spencer, KR | 1 |
| Chang, M; Perry, JA | 1 |
| Biessels, PT; Damsma, G; De Vries, JB; Horn, AS; Westerink, BH | 1 |
| Agoston, S; Biessels, PT; Horn, AS; Houwertjes, MC | 1 |
| Agoston, S; Biessels, PT; Horn, AS; Houwertjes, MC; Scaf, AH | 1 |
| Agoston, S; Biessels, PT; Horn, AS | 1 |
| Freyss-Béguin, M; Griffaton, G; Lechat, P; Millanvoye-Van Brussel, E | 1 |
| Stolc, S; Vlcková, E | 1 |
| Gibson, GE; Peterson, C | 1 |
| Agoston, S; Biessels, P; Den Hertog, A; Pielkenrood, J | 1 |
| Birdsall, B; Burgen, AS; Roberts, GC | 1 |
| Birdsall, B; Feeney, J; Polshakov, VI | 1 |
| Anderson, AC; Joska, TM | 1 |
| Corless, MD; Gaulier, SM; Horne, VA; Kinloch, RA; Maw, GN; Owen, DR; Pearce, DW; Rees, H; Ringer, TJ; Rodriguez-Lens, M; Ryckmans, T; Stammen, BL | 1 |
| Ando, M; Ito, H; Ito, S; Kameda, M; Kanno, T; Kawamoto, H; Kobayashi, K; Miyazoe, H; Nakama, C; Sato, N; Suzuki, T; Tahara, Y; Tanaka, S; Tanaka, T; Tani, T; Tokita, S; Tsujino, T | 1 |
| Ando, M; Ito, S; Kameda, M; Kawamoto, H; Kobayashi, K; Nakama, C; Ozaki, S; Sato, N; Suzuki, T; Tani, T; Tokita, S | 1 |
| Allen, A; Chaturvedi, P; Dubrovskiy, A; Etter, J; Harding, TC; Haringsma, H; Karp, R; Labenski, MT; Lee, K; Martin, TS; Medikonda, A; Nacht, M; Niu, D; Petter, RC; Raponi, M; Ren, Y; Sheets, M; Simmons, AD; Singh, J; Tester, R; Tjin Tham Sjin, R; Walter, AO; Westlin, WF; Zhu, Z | 1 |
| Bursulaya, B; Chen, B; Hood, T; Jiang, T; Jin, Y; Kim, S; Lee, C; Li, N; Liu, B; Lu, W; Marsilje, TH; Michellys, PY; Nguyen, TN; Pei, W; Steffy, A; Sun, F; Tuntland, T; Uno, T; Wu, B; Zhu, X | 1 |
19 other study(ies) available for 2,4-diaminopyridine and 4-aminopyridine
| Article | Year |
|---|---|
2,4-Diamino-5-benzylpyrimidines and analogues as antibacterial agents. 3. C-Benzylation of aminopyridines with phenolic Mannich bases. Synthesis of 1- and 3-deaza analogues of trimethoprim.
Topics: Animals; Anti-Bacterial Agents; Bacteria; Escherichia coli; Folic Acid Antagonists; In Vitro Techniques; Mannich Bases; Phenols; Rats; Structure-Activity Relationship; Trimethoprim | 1980 |
Comparison of DuP 996, with physostigmine, THA and 3,4-DAP on hypoxia-induced amnesia in rats.
Topics: 4-Aminopyridine; Amnesia; Animals; Avoidance Learning; Hypoxia; Indoles; Male; Oxygen Consumption; Parasympathetic Nervous System; Physostigmine; Pyridines; Rats; Rats, Inbred Strains; Tacrine | 1990 |
Sensitive trace-first liquid chromatographic determination of 4-aminopyridine in 3,4-diaminopyridine.
Topics: 4-Aminopyridine; Chromatography, High Pressure Liquid | 1990 |
Differential effects of 4-aminopyridine and 2,4-diaminopyridine on the in vivo release of acetylcholine and dopamine in freely moving rats measured by intrastriatal dialysis.
Topics: 4-Aminopyridine; Acetylcholine; Aminopyridines; Animals; Brain; Corpus Striatum; Dialysis; Dopamine; Injections; Male; Rats; Rats, Inbred Strains; Tetrodotoxin | 1988 |
A comparison of the pharmacological actions of 4-aminopyridine and two of its derivatives in the monkey.
Topics: 4-Aminopyridine; Aminopyridines; Anesthetics; Animals; Diazepam; Female; Heart Rate; Ketamine; Macaca nemestrina; Male; Neuromuscular Depolarizing Agents | 1987 |
Pharmacokinetics and pharmacodynamics of 2,4-diaminopyridine in the cat.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Biotransformation; Blood Pressure; Cats; Heart Rate | 1988 |
High-performance liquid chromatographic determination of 2,4-diaminopyridine in plasma and urine.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Cats; Crystallization; Spectrophotometry, Ultraviolet | 1987 |
3,4-Diaminopyridine partially reverses phospholipid breakdown induced by oxygen deprivation of cultured myocardial cells.
Topics: 4-Aminopyridine; Aminopyridines; Anaerobiosis; Animals; Cells, Cultured; Heart; Kinetics; Myocardium; Phospholipids; Rats; Rats, Inbred Strains | 1986 |
Facilitatory effect of some drugs on transmission in the frog sympathetic ganglion.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Dimethyl Sulfoxide; Evoked Potentials; Ganglia, Sympathetic; In Vitro Techniques; Rana esculenta; Rana temporaria; Stimulation, Chemical; Synaptic Membranes; Synaptic Transmission | 1982 |
Aging and 3,4-diaminopyridine alter synaptosomal calcium uptake.
Topics: 4-Aminopyridine; Aging; Aminopyridines; Animals; Biological Transport, Active; Brain; Calcium; Kinetics; Potassium; Rats; Rats, Inbred F344; Synaptosomes | 1983 |
The effect of some new aminopyridines on mammalian non-myelinated nerve fibres.
Topics: 4-Aminopyridine; Action Potentials; Amifampridine; Aminopyridines; Animals; Biological Transport, Active; Guinea Pigs; In Vitro Techniques; Nerve Fibers; Sodium; Vagus Nerve | 1983 |
Effects of coenzyme analogues on the binding of p-aminobenzoyl-L-glutamate and 2,4-diaminopyrimidine to Lactobacillus casei dihydrofolate reductase.
Topics: 4-Aminobenzoic Acid; 4-Aminopyridine; Aminobenzoates; Aminopyridines; Binding Sites; Glutamates; Kinetics; Lacticaseibacillus casei; Mathematics; NADP; Oxidation-Reduction; para-Aminobenzoates; Protein Binding; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase; Thermodynamics | 1980 |
NMR studies of ligand carboxylate group interactions with arginine residues in complexes of Lactobacillus casei dihydrofolate reductase with substrates and substrate analogues.
Topics: 4-Aminopyridine; Amino Acid Sequence; Arginine; Carboxylic Acids; Conserved Sequence; Folic Acid; Glutamates; Hydrogen Bonding; Lacticaseibacillus casei; Ligands; Methotrexate; NADP; Nuclear Magnetic Resonance, Biomolecular; Static Electricity; Tetrahydrofolate Dehydrogenase | 2000 |
Structure-activity relationships of Bacillus cereus and Bacillus anthracis dihydrofolate reductase: toward the identification of new potent drug leads.
Topics: 4-Aminopyridine; Amino Acid Sequence; Anti-Bacterial Agents; Bacillus anthracis; Bacillus cereus; Binding Sites; Drug Design; Folic Acid Antagonists; Humans; Microbial Sensitivity Tests; Models, Molecular; Sequence Alignment; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase | 2006 |
2,4-Diaminopyridine delta-opioid receptor agonists and their associated hERG pharmacology.
Topics: 4-Aminopyridine; Analgesics, Opioid; Animals; Cell Line; Chemistry, Pharmaceutical; Combinatorial Chemistry Techniques; Drug Design; Electromyography; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Rats; Receptors, Opioid, delta; Structure-Activity Relationship | 2009 |
Optimization of a series of 2,4-diaminopyridines as neuropeptide Y Y1 receptor antagonists with reduced hERG activity.
Topics: 4-Aminopyridine; Animals; Cell Line; Chemistry, Pharmaceutical; CHO Cells; Cricetinae; Cricetulus; Drug Design; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Hydrogen-Ion Concentration; Inhibitory Concentration 50; Models, Chemical; Receptors, Neuropeptide Y; Recombinant Proteins; Structure-Activity Relationship | 2009 |
Synthesis and evaluation of a series of 2,4-diaminopyridine derivatives as potential positron emission tomography tracers for neuropeptide Y Y1 receptors.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Cell Line; CHO Cells; Cricetinae; Cricetulus; Humans; Positron-Emission Tomography; Receptors, Neuropeptide Y; Recombinant Proteins; Structure-Activity Relationship; Thiazoles | 2009 |
In vitro and in vivo characterization of irreversible mutant-selective EGFR inhibitors that are wild-type sparing.
Topics: 4-Aminopyridine; Animals; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Clinical Trials as Topic; Drug Resistance, Neoplasm; ErbB Receptors; Humans; In Vitro Techniques; Mice; Mutation; Neoplasm Recurrence, Local; Xenograft Model Antitumor Assays | 2014 |
Design and synthesis of novel selective anaplastic lymphoma kinase inhibitors.
Topics: 4-Aminopyridine; Anaplastic Lymphoma Kinase; Animals; Antineoplastic Agents; Binding Sites; Cell Line, Tumor; Crystallography, X-Ray; Drug Design; Half-Life; Humans; Lymphoma, Large-Cell, Anaplastic; Mice; Mice, SCID; Microsomes, Liver; Molecular Dynamics Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Rats; Receptor Protein-Tyrosine Kinases; Structure-Activity Relationship; Transplantation, Heterologous | 2016 |