2,4-diamino-5-phenyl-6-methylpyrimidine has been researched along with trimethoprim in 2 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Intaraudom, C; Kamchonwongpaisan, S; Phupong, W; Sirawaraporn, W; Sirichaiwat, C; Tarnchompoo, B; Thebtaranonth, Y; Vanichtanankul, J; Yuthavong, Y | 1 |
| El-Hamamsy, MH; Smith, AW; Thompson, AS; Threadgill, MD | 1 |
2 other study(ies) available for 2,4-diamino-5-phenyl-6-methylpyrimidine and trimethoprim
| Article | Year |
|---|---|
Development of 2,4-diaminopyrimidines as antimalarials based on inhibition of the S108N and C59R+S108N mutants of dihydrofolate reductase from pyrimethamine-resistant Plasmodium falciparum.
Topics: Animals; Antimalarials; Binding, Competitive; Chlorocebus aethiops; Folic Acid Antagonists; Humans; KB Cells; Malaria, Falciparum; Plasmodium falciparum; Point Mutation; Pyrimethamine; Pyrimidines; Tetrahydrofolate Dehydrogenase; Vero Cells | 2002 |
Structure-based design, synthesis and preliminary evaluation of selective inhibitors of dihydrofolate reductase from Mycobacterium tuberculosis.
Topics: Antitubercular Agents; Binding Sites; Folic Acid Antagonists; Glycerol; Humans; Indicators and Reagents; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Models, Molecular; Mycobacterium avium Complex; Mycobacterium tuberculosis; Saccharomyces cerevisiae; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase | 2007 |