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2,4-diamino-5-adamantyl-6-methylpyrimidine and methotrexate

2,4-diamino-5-adamantyl-6-methylpyrimidine has been researched along with methotrexate in 2 studies

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19902 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cody, V; Zakrzewski, SF1
Hamrell, MR1

Other Studies

2 other study(ies) available for 2,4-diamino-5-adamantyl-6-methylpyrimidine and methotrexate

ArticleYear
Molecular structures of 2,4-diaminopyrimidine antifolates with antineoplastic activity.
    Journal of medicinal chemistry, 1982, Volume: 25, Issue:4

    Topics: Antineoplastic Agents; Folic Acid Antagonists; Hydrogen Bonding; Models, Molecular; Molecular Conformation; Pyrimidines; Structure-Activity Relationship

1982
Inhibition of dihydrofolate reductase and cell growth by antifolates in a methotrexate-resistant cell line.
    Oncology, 1984, Volume: 41, Issue:5

    Topics: Adamantane; Animals; Aspartic Acid; Cell Division; Cell Line; Drug Resistance; Folic Acid Antagonists; Methotrexate; Mice; Pyrimethamine; Pyrimidines

1984