2,4,6-triamino-5-chloroquinazoline has been researched along with wr 158122 in 3 studies
| Studies (2,4,6-triamino-5-chloroquinazoline) | Trials (2,4,6-triamino-5-chloroquinazoline) | Recent Studies (post-2010) (2,4,6-triamino-5-chloroquinazoline) | Studies (wr 158122) | Trials (wr 158122) | Recent Studies (post-2010) (wr 158122) |
|---|---|---|---|---|---|
| 5 | 0 | 0 | 21 | 0 | 2 |
| Protein | Taxonomy | 2,4,6-triamino-5-chloroquinazoline (IC50) | wr 158122 (IC50) |
|---|---|---|---|
| Dihydrofolate reductase | Rattus norvegicus (Norway rat) | 0.004 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fukunaga, JY; Hansch, C; Steller, EE | 1 |
| Crippen, GM; Ghose, AK | 1 |
| Battershell, C; Hopfinger, AJ; Malhotra, D | 1 |
3 other study(ies) available for 2,4,6-triamino-5-chloroquinazoline and wr 158122
| Article | Year |
|---|---|
Inhibition of dihydrofolate reductase. Structure-activity correlations of quinazolines.
Topics: Binding Sites; Folic Acid Antagonists; Liver; Molecular Conformation; Quinazolines; Structure-Activity Relationship | 1976 |
Combined distance geometry analysis of dihydrofolate reductase inhibition by quinazolines and triazines.
Topics: Chemical Phenomena; Chemistry; Folic Acid Antagonists; Molecular Conformation; Quinazolines; Streptococcus; Structure-Activity Relationship; Triazines | 1983 |
Inhibition of dihydrofolate reductase: structure-activity correlations of quinazolines based upon molecular shape analysis.
Topics: Chemical Phenomena; Chemistry, Physical; Folic Acid Antagonists; Models, Molecular; Molecular Conformation; Quinazolines; Structure-Activity Relationship | 1981 |