2,4,5,2',4',5'-hexachlorobiphenyl has been researched along with phenobarbital in 12 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (58.33) | 18.7374 |
| 1990's | 5 (41.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ariyoshi, N; Koga, N; Oguri, K; Yoshimura, H | 1 |
| Bourque, DP; Ciaccio, PJ; Elhag, GA; Graves, PE; Halpert, JR | 1 |
| Buchmann, A; Kunz, W; Oesch, F; Robertson, LW; Wolf, CR | 1 |
| de Vries, J; Groot, GS; Scholte, BJ; te Velde, B | 1 |
| Lech, JJ; Rau, LA; Vodicnik, MJ | 1 |
| Ahotupa, M; Mäntylä, E | 1 |
| Nagata, K; Yoshihara, S; Yoshimura, H | 1 |
| Cameron, RC; Farber, E; Hayes, MA; Jago, MV; Roberts, E; Safe, SH | 1 |
| Albro, PW; Gupta, BN; Kohli, KK; McKinney, JD | 1 |
| Ganem, LG; Ikegwuonu, FI; Jefcoate, CR; Larson, MC; Shen, X | 1 |
| Birnbaum, LS; DeVito, MJ; Riddle, MM; Smialowicz, RJ; Williams, WC | 1 |
| Anderson, A; Ganem, LG; Jefcoate, CR; Trottier, E | 1 |
12 other study(ies) available for 2,4,5,2',4',5'-hexachlorobiphenyl and phenobarbital
| Article | Year |
|---|---|
Metabolism of 2,4,5,2',4',5'-hexachlorobiphenyl with liver microsomes of phenobarbital-treated dog; the possible formation of PCB 2,3-arene oxide intermediate.
Topics: Animals; Biotransformation; Chromatography, Gas; Chromatography, Thin Layer; Dogs; Epoxy Compounds; Gas Chromatography-Mass Spectrometry; Glutathione; In Vitro Techniques; Magnetic Resonance Spectroscopy; Male; Microsomes, Liver; Phenobarbital; Polychlorinated Biphenyls | 1992 |
cDNA and deduced amino acid sequences of a dog hepatic cytochrome P450IIB responsible for the metabolism of 2,2',4,4',5,5'-hexachlorobiphenyl.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cloning, Molecular; Cytochrome P-450 Enzyme System; DNA; Dogs; Enzyme Induction; Liver; Male; Molecular Sequence Data; Phenobarbital; Polychlorinated Biphenyls; Species Specificity | 1990 |
Polychlorinated biphenyls, classified as either phenobarbital- or 3-methylcholanthrene-type inducers of cytochrome P-450, are both hepatic tumor promoters in diethylnitrosamine-initiated rats.
Topics: Animals; Cocarcinogenesis; Cytochrome P-450 Enzyme System; Diethylnitrosamine; Enzyme Induction; Female; Isoenzymes; Liver; Liver Neoplasms, Experimental; Methylcholanthrene; Phenobarbital; Polychlorinated Biphenyls; Rats | 1986 |
Induction of cytochrome P-450b,e-type isozymes by polychlorinated biphenyls in rat liver. Molecular cloning of induced mRNAs.
Topics: Animals; Base Sequence; Cloning, Molecular; Cytochrome P-450 Enzyme System; DNA; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Immunochemistry; Isoelectric Focusing; Isoenzymes; Liver; Male; Phenobarbital; Polychlorinated Biphenyls; Protein Biosynthesis; Rabbits; Rats; Rats, Inbred Strains; RNA, Messenger | 1985 |
The effect of monooxygenase inducing agents on the incorporation of [35S]methionine into hepatic microsomal protein of rainbow trout (Salmo gairdneri).
Topics: Animals; Autoradiography; Benzoflavones; beta-Naphthoflavone; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Methionine; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Polychlorinated Biphenyls; Rosaniline Dyes; Salmonidae; Time Factors; Trout | 1984 |
Adipose tissue content as a modifier of the tissue distribution, biological effects, and excretion of a hexachlorobiphenyl in C57BL/6J and DBA/JBOMf mice.
Topics: Adipose Tissue; Animals; Cytosol; Enzyme Induction; Male; Methylcholanthrene; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Polychlorinated Biphenyls; Species Specificity; Tissue Distribution | 1983 |
Different responsiveness of hepatic and pulmonary microsomal mixed function oxidases to phenobarbital-type and 3-methylcholanthrene-type polychlorinated biphenyls in rats.
Topics: Animals; Benzoflavones; Cytochrome P-450 Enzyme System; Enzyme Induction; Lung; Male; Methylcholanthrene; Microsomes; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Polychlorinated Biphenyls; Proadifen; Rats; Rats, Inbred Strains | 1983 |
Influences of various xenobiotic inducers on cytocidal toxicity of lasiocarpine and senecionine in primary cultures of rat hepatocytes.
Topics: Animals; Carcinogens; Cells, Cultured; Cytochrome P-450 Enzyme System; Enzyme Induction; Liver; Male; Methylcholanthrene; Phenobarbital; Polychlorinated Biphenyls; Proadifen; Pyrrolizidine Alkaloids; Rats; Rats, Inbred F344 | 1984 |
Effects of inducers of drug metabolism enzymes on triglyceride and phospholipid biosynthesis.
Topics: Animals; Enzyme Induction; Male; Methylcholanthrene; Mice; Microsomes, Liver; Phenobarbital; Phospholipids; Polychlorinated Biphenyls; Rats; Triglycerides | 1981 |
The regulation by gender, strain, dose, and feeding status of the induction of multiple forms of cytochrome P450 isozymes in rat hepatic microsomes by 2,4,5,2',4',5'-hexachlorobiphenyl.
Topics: Animal Feed; Animals; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Female; GABA Modulators; Growth Hormone; Immunoblotting; Isoenzymes; Male; Microsomes, Liver; Phenobarbital; Polychlorinated Biphenyls; Rats; Rats, Inbred F344; Sex Characteristics; Species Specificity; Structure-Activity Relationship; Testosterone; Triiodothyronine | 1996 |
Opposite effects of 2,2',4,4',5,5'-hexachlorobiphenyl and 2,3,7,8-tetrachlorodibenzo-p-dioxin on the antibody response to sheep erythrocytes in mice.
Topics: Animals; Antibody Formation; Body Weight; Cytochrome P-450 CYP2B1; Drug Interactions; Erythrocytes; Female; In Vitro Techniques; Liver; Mice; Organ Size; Phenobarbital; Polychlorinated Biphenyls; Polychlorinated Dibenzodioxins; Sheep; Spleen; Thymus Gland | 1997 |
Phenobarbital induction of CYP2B1/2 in primary hepatocytes: endocrine regulation and evidence for a single pathway for multiple inducers.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Cells, Cultured; Cytochrome P-450 CYP2B1; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Hormones; Liver; Methimazole; Mitotane; Phenobarbital; Polychlorinated Biphenyls; Rats; Rats, Inbred F344; Rats, Inbred WF; Species Specificity; Steroid Hydroxylases; Thyroid Hormones | 1999 |