Compounds > 2,4,5,2',4',5'-hexachlorobiphenyl
Page last updated: 2024-08-23

2,4,5,2',4',5'-hexachlorobiphenyl and 3,4,5,3',4'-pentachlorobiphenyl

2,4,5,2',4',5'-hexachlorobiphenyl has been researched along with 3,4,5,3',4'-pentachlorobiphenyl in 64 studies

Research

Studies (64)

TimeframeStudies, this research(%)All Research%
pre-19903 (4.69)18.7374
1990's9 (14.06)18.2507
2000's31 (48.44)29.6817
2010's19 (29.69)24.3611
2020's2 (3.13)2.80

Authors

AuthorsStudies
Karplus, M; So, SS1
Hokama, Y; Koga, N; Nagano, I; Yoshimura, H1
Handa, S; Kiyohara, C; Kuratsune, M; Masuda, Y; Nagayama, J1
Nagata, K; Yoshihara, S; Yoshimura, H1
Ahlborg, UG; Bergman, A; Flodström, S; Hemming, H; Kronevi, T; Nordgren, I; Wärngård, L1
Ahlborg, UG; Bager, Y; Flodström, S; Hemming, H; Wärngård, L1
Aoki, Y; Tanno, K1
Edwards, JF; Kocurek, N; Kubena, LF; Mayura, K; Phillips, TD; Safe, SH; Zhao, F1
Bager, Y; Kato, Y; Kenne, K; Wärngård, L1
Elliott, JE; Kennedy, SW; Lorenzen, A1
Fransson-Steen, R; Haag-Grönlund, M; Hâkansson, H; Johansson, N; Scheu, G; Wärngård, L1
Desaulniers, D; Fintelman, E; Foster, WG; Leingartner, K; Wade, M; Yagminas, A1
Englander, EW; Greeley, GH; He, Q; Lee, HM1
Catron, TF; Walker, MK1
Gregoraszczuk, EL; Lyche, JL; Ropstad, E; Wójtowicz, AK1
Augustowska, K; Gregoraszczuk, EL; Kajta, M; Ropstad, E; Wójtowicz, A1
Lee, SK; Ou, YC; Yang, RS1
Benjamin, SA; Chubb, LS; Dean, CE; Keefe, TJ; Tessari, JD1
Craft, ES; Crofton, KM; DeVito, MJ1
Chrzaszcz, R; Gregoraszczuk, EL; Grochowalski, A; Wegiel, M1
Bláha, L; Machala, M; Scott, J; Trosko, JE; Upham, BL; Vondrácek, J1
Dahl, E; Johansen, G; Larsen, H; Lyche, J; Ropstad, E; Skaare, JU; Tverdal, A1
Dahl, E; Farstad, W; Lyche, JL; Oskam, IC; Reksen, O; Ropstad, E; Skaare, JU; Sweeney, T1
Olson, JR; Vezina, CM; Walker, NJ1
Goch, M; Gregoraszczuk, EL; Wójtowicz, AK1
Dahl, E; Krogenaes, A; Lyche, JL; Oskam, IC; Ropstad, E; Skaare, JU; Stien, A; Sweeney, T; Thomassen, R; Wiger, R1
Hagemann, S; Hanf, V; Köhn, FM; Körner, W; Müller, C; Pflieger-Bruss, S; Schill, WB1
Johansen, GM; Larsen, HJ; Lyche, JL; Ropstad, E; Skaare, JU; Tverdal, A1
Fischer, B; Nestler, D; Pocar, P; Risch, M1
Augustowska, K; Gregoraszczuk, EL; Tomanek, M; Wojtowicz, A1
Andersen, ME; Lee, SK; Ou, YC; Yang, RS1
Lin, CH; Lin, PH1
Aleksandersen, M; Larsson, S; Lind, PM; Lundberg, R; Lyche, JL; Orberg, J; Rönn, M; Ropstad, E; Skaare, JU1
Ceccatelli, S; Goldoni, M; Johansson, C; Mutti, A; Tamm, C; Tofighi, R1
Matsuyama, K; Mitsuhara, Y; Noma, Y; Sakai, S1
Costa, LG; Fattori, V; Giordano, G; Vitalone, A1
Bernocchi, G; Castoldi, AF; Coccini, T; Goldoni, M; Manzo, L; Poli, D; Roda, E1
Cauli, O; Erceg, S; Felipo, V; Monfort, P; Piedrafita, B1
Andrysík, Z; Hofmanová, J; Kozubík, A; Machala, M; Neca, J; Trosko, JE; Umannová, L; Upham, BL; Vondrácek, J1
Dahl, E; Gutleb, AC; Krogenaes, A; Lyche, JL; Oskam, IC; Ropstad, E; Skaare, JU; Zimmer, KE1
Felipo, V; Llansola, M; Montoliu, C; Piedrafita, B; Rodrigo, R1
Brix, AE; Jokinen, MP; Kissling, GE; Nyska, A; Orzech, DP; Sells, DM; Walker, NJ; Wyde, M; Yoshizawa, K1
Chen, L; Chen, X; Chen, Y; Shen, C; Shen, K1
Ellison, CA; Olson, JR; Ovando, BJ; Vezina, CM1
Anschutz, P; Budzinski, H; Cachot, J; Deflandre, B; Etcheber, H; LeMenach, K; Leray-Forget, J; Morin, B; Peluhet, L; Vicquelin, L1
Carletti, M; Girolami, F; Nebbia, C; Perona, G; Rasero, R; Sacchi, P; Spalenza, V1
Barouki, R; Benelli, C; Bui, LC; Chevallier, A; Clément, K; Forest, C; Guyot, E; Kim, MJ; Pelloux, V; Tordjman, J1
Caglieri, A; Costa, LG; Giordano, G; Goldoni, M; Mutti, A; Pellacani, C; Tagliaferri, S1
Barrett, JR1
Alberghina, D; Calò, M; Casella, S; Lo Cascio, P; Panzera, M; Piccione, G1
Cauli, O; Felipo, V; Llansola, M; Piedrafita, B1
Appel, KE; Buchmann, A; Chahoud, I; Gavrilov, A; Grote, K; Kania-Korwel, I; Kopp-Schneider, A; Krause, E; Lehmler, HJ; Rignall, B; Robertson, LW; Schwarz, M; Weimer, M1
Kowalik, M; Mlynarczuk, J1
Hrabia, A; Leśniak, A; Sechman, A1
Fowler, PA; Krogenæs, A; Ropstad, E; Tremoen, NH; Verhaegen, S1
Chen, Q; Chen, Y; Dong, S; Huang, Q; Lin, Y; Sun, X; Zhang, H; Zhu, M1
Hrabia, A; Katarzyńska, D; Kowalik, K; Sechman, A1
Bogazzi, F; Cappellani, D; Lupi, I; Manetti, L; Marcocci, C; Martino, E; Raggi, F; Russo, D; Sardella, C; Tomisti, L; Urbani, C1
Antos, PA; Batoryna, M; Hrabia, A; Sechman, A1
Hennig, B; Petriello, MC; Wang, C; Zhu, B1
Li, Z; Song, L; Zhang, Y1
Cai, J; Gui, W; Koo, I; Liu, Q; Nichols, RG; Patterson, AD; Rimal, B; Smith, PB; Tian, Y1
Birnbaum, LS; Bonner, MR; Kostyniak, PJ; Olson, JR; Ren, X; VanEtten, SL; Wang, J1

Other Studies

64 other study(ies) available for 2,4,5,2',4',5'-hexachlorobiphenyl and 3,4,5,3',4'-pentachlorobiphenyl

ArticleYear
Three-dimensional quantitative structure-activity relationships from molecular similarity matrices and genetic neural networks. 2. Applications.
    Journal of medicinal chemistry, 1997, Dec-19, Volume: 40, Issue:26

    Topics: Cholinesterase Inhibitors; Dopamine beta-Hydroxylase; Drug Design; Enzyme Inhibitors; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Molecular Conformation; Molecular Structure; Neural Networks, Computer; Phosphorylases; Receptors, Aryl Hydrocarbon; Static Electricity; Structure-Activity Relationship

1997
[Acute toxicity and inductive effect on liver enzyme activities of 3,4,5,3',4'-pentachlorobiphenyl in chickens].
    Fukuoka igaku zasshi = Hukuoka acta medica, 1985, Volume: 76, Issue:5

    Topics: Animals; Chickens; Enzyme Induction; Liver; Male; Polychlorinated Biphenyls

1985
Effects of chlorinated dibenzofuran and dioxin on concentration and pattern of chlorobiphenyls and activity of benzo(a)pyrene hydroxylation in mice.
    Fukuoka igaku zasshi = Hukuoka acta medica, 1985, Volume: 76, Issue:5

    Topics: Adipose Tissue; Animals; Aryl Hydrocarbon Hydroxylases; Benzofurans; Dioxins; Liver; Lung; Male; Mice; Mice, Inbred Strains; Polychlorinated Biphenyls

1985
Different responsiveness of hepatic and pulmonary microsomal mixed function oxidases to phenobarbital-type and 3-methylcholanthrene-type polychlorinated biphenyls in rats.
    Journal of pharmacobio-dynamics, 1983, Volume: 6, Issue:12

    Topics: Animals; Benzoflavones; Cytochrome P-450 Enzyme System; Enzyme Induction; Lung; Male; Methylcholanthrene; Microsomes; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Polychlorinated Biphenyls; Proadifen; Rats; Rats, Inbred Strains

1983
Relative tumour promoting activity of three polychlorinated biphenyls in rat liver.
    European journal of pharmacology, 1993, Aug-02, Volume: 248, Issue:2

    Topics: Animals; Carcinogens; Female; gamma-Glutamyltransferase; Glutathione Transferase; Liver; Liver Neoplasms, Experimental; Polychlorinated Biphenyls; Polychlorinated Dibenzodioxins; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship

1993
Interaction of 3,4,5,3',4'-pentachlorobiphenyl and 2,4,5,2',4',5'-hexachlorobiphenyl in promotion of altered hepatic foci in rats.
    Pharmacology & toxicology, 1995, Volume: 77, Issue:2

    Topics: Animals; Carcinogens; Diethylnitrosamine; Drug Interactions; Enzymes; Female; Hepatectomy; Liver; Polychlorinated Biphenyls; Rats; Rats, Sprague-Dawley

1995
Phosphorylation of c-Jun stimulated in primary cultured rat liver parenchymal cells by a coplanar polychlorinated biphenyl.
    The Biochemical journal, 1996, Feb-01, Volume: 313 ( Pt 3)

    Topics: Animals; Cells, Cultured; Epidermal Growth Factor; Liver; Phosphorylation; Polychlorinated Biphenyls; Proto-Oncogene Proteins c-jun; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate

1996
Inhibition of 3,3',4,4',5-pentachlorobiphenyl-induced chicken embryotoxicity by 2,2',4,4',5,5'-hexachlorobiphenyl.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1997, Volume: 35, Issue:1

    Topics: Abnormalities, Drug-Induced; Animals; Beak; Chick Embryo; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Nonmammalian; Embryonic and Fetal Development; Eye Abnormalities; Liver; Polychlorinated Biphenyls; Wings, Animal

1997
The ability to alter the gap junction protein expression outside GST-P positive foci in liver of rats was associated to the tumour promotion potency of different polychlorinated biphenyls.
    Chemico-biological interactions, 1997, Mar-14, Volume: 103, Issue:3

    Topics: Animals; Blotting, Western; Carcinogens; Connexin 26; Connexins; Female; Gap Junction beta-1 Protein; Glutathione Transferase; Liver; Polychlorinated Biphenyls; Polychlorinated Dibenzodioxins; Rats; Rats, Sprague-Dawley

1997
Comparative toxicity of polychlorinated biphenyls to Japanese quail (Coturnix c. japonica) and American kestrels (Falco sparverius).
    Journal of toxicology and environmental health, 1997, Volume: 51, Issue:1

    Topics: Aminopyrine N-Demethylase; Animals; Aroclors; Aryl Hydrocarbon Hydroxylases; Birds; Carcinogens; Chlorodiphenyl (54% Chlorine); Coturnix; Cytochrome P-450 CYP1A1; Drug Residues; Female; Kidney; Liver; Organ Size; Polychlorinated Biphenyls; Porphyrins; Species Specificity

1997
Interactive effects of three structurally different polychlorinated biphenyls in a rat liver tumor promotion bioassay.
    Toxicology and applied pharmacology, 1998, Volume: 152, Issue:1

    Topics: Animals; Body Weight; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2B1; Diethylnitrosamine; Dose-Response Relationship, Drug; Drug Interactions; Female; Glutathione Transferase; Kidney; Liver; Liver Neoplasms, Experimental; Organ Size; Polychlorinated Biphenyls; Rats; Rats, Sprague-Dawley; Retinoids

1998
Effects of acute exposure to PCBs 126 and 153 on anterior pituitary and thyroid hormones and FSH isoforms in adult Sprague Dawley male rats.
    Toxicological sciences : an official journal of the Society of Toxicology, 1999, Volume: 47, Issue:2

    Topics: Animals; Estrogen Antagonists; Follicle Stimulating Hormone; Growth Hormone; Luteinizing Hormone; Male; Pituitary Hormones, Anterior; Polychlorinated Biphenyls; Prolactin; Rats; Rats, Sprague-Dawley; Testosterone; Thyroid Hormones; Toxicity Tests; Weight Gain

1999
Endocrine disruptive effects of polychlorinated aromatic hydrocarbons on intestinal cholecystokinin in rats.
    Endocrinology, 2000, Volume: 141, Issue:8

    Topics: Animals; Aspartic Acid Endopeptidases; Benzofurans; Cell Line; Cholecystokinin; Chromogranin A; Chromogranins; Duodenum; Female; Hydrocarbons, Aromatic; Hydrocarbons, Chlorinated; Insulin-Like Growth Factor Binding Protein 3; Intestinal Mucosa; Intestines; Mice; Polychlorinated Biphenyls; Polychlorinated Dibenzodioxins; Proprotein Convertase 2; Proprotein Convertases; Rats; Rats, Sprague-Dawley; RNA, Messenger; Subtilisins

2000
Characterization of cardiotoxicity induced by 2,3,7, 8-tetrachlorodibenzo-p-dioxin and related chemicals during early chick embryo development.
    Toxicology and applied pharmacology, 2000, Sep-15, Volume: 167, Issue:3

    Topics: Actins; Animals; Atrial Natriuretic Factor; Blotting, Northern; Chick Embryo; Dose-Response Relationship, Drug; Electrocardiography; Embryo, Nonmammalian; Environmental Pollutants; Heart; Heart Rate; Isoproterenol; Organ Size; Polychlorinated Biphenyls; Polychlorinated Dibenzodioxins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Species Specificity

2000
Time dependent and cell-specific action of polychlorinated biphenyls (PCB 153 and PCB 126) on steroid secretion by porcine theca and granulosa cells in mono- and co-culture.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2000, Volume: 51, Issue:3

    Topics: Animals; Cells, Cultured; Estradiol; Estrogen Antagonists; Female; Granulosa Cells; Polychlorinated Biphenyls; Progesterone; Steroids; Swine; Testosterone; Theca Cells; Time Factors

2000
Polichlorinated biphenyls (PCB126 and PCB 153) action on proliferation and progesterone secretion by cultured in vitro porcine luteal cells.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2001, Volume: 109, Issue:8

    Topics: Animals; Cell Division; Cell Survival; Cells, Cultured; Culture Media; Dose-Response Relationship, Drug; Estrogen Antagonists; Female; Luteal Cells; Polychlorinated Biphenyls; Progesterone; Swine; Time Factors

2001
Comparison of pharmacokinetic interactions and physiologically based pharmacokinetic modeling of PCB 153 and PCB 126 in nonpregnant mice, lactating mice, and suckling pups.
    Toxicological sciences : an official journal of the Society of Toxicology, 2002, Volume: 65, Issue:1

    Topics: Adipose Tissue; Animals; Body Weight; Drug Interactions; Estrogen Antagonists; Female; Lactation; Liver; Maternal Exposure; Mice; Mice, Inbred C57BL; Models, Biological; Multiple Chemical Sensitivity; Polychlorinated Biphenyls; Pregnancy; Time Factors; Tissue Distribution

2002
Nonadditive hepatic tumor promoting effects by a mixture of two structurally different polychlorinated biphenyls in female rat livers.
    Toxicological sciences : an official journal of the Society of Toxicology, 2002, Volume: 66, Issue:1

    Topics: Adipose Tissue; Animals; Body Weight; Carcinogens; Constitutive Androstane Receptor; Diethylnitrosamine; Drug Interactions; Female; Glutathione Transferase; Liver; Liver Neoplasms; Organ Size; Polychlorinated Biphenyls; Rats; Rats, Inbred F344; Receptors, Cytoplasmic and Nuclear; Transcription Factors

2002
Comparative responsiveness of hypothyroxinemia and hepatic enzyme induction in Long-Evans rats versus C57BL/6J mice exposed to TCDD-like and phenobarbital-like polychlorinated biphenyl congeners.
    Toxicological sciences : an official journal of the Society of Toxicology, 2002, Volume: 68, Issue:2

    Topics: Animals; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2B1; Dose-Response Relationship, Drug; Enzyme Induction; Estrogen Antagonists; Female; Glucuronosyltransferase; Male; Mice; Mice, Inbred C57BL; Microsomes, Liver; Polychlorinated Biphenyls; Rats; Rats, Long-Evans; Species Specificity; Thyroxine

2002
Congener-specific accumulation of polychlorinated biphenyls in ovarian follicular wall follows repeated exposure to PCB 126 and PCB 153. Comparison of tissue levels of PCB and biological changes.
    Chemosphere, 2003, Volume: 50, Issue:4

    Topics: Animals; Environmental Pollutants; Female; Gonadal Steroid Hormones; Ovarian Follicle; Polychlorinated Biphenyls; Swine; Tissue Distribution

2003
Inhibition of gap junctional intercellular communication by noncoplanar polychlorinated biphenyls: inhibitory potencies and screening for potential mode(s) of action.
    Toxicological sciences : an official journal of the Society of Toxicology, 2003, Volume: 76, Issue:1

    Topics: Animals; Blotting, Western; Cell Line; Epidermal Growth Factor; Epithelial Cells; Gap Junctions; Liver; Mitogen-Activated Protein Kinases; Polychlorinated Biphenyls; Rats; Signal Transduction; Sphingomyelin Phosphodiesterase; src-Family Kinases; Tetradecanoylphorbol Acetate

2003
Effects of perinatal exposure to low doses of PCB 153 and PCB 126 on lymphocyte proliferation and hematology in goat kids.
    Journal of toxicology and environmental health. Part A, 2004, Jun-11, Volume: 67, Issue:11

    Topics: Adipose Tissue; Administration, Oral; Animals; Animals, Newborn; Blood Cell Count; Dose-Response Relationship, Drug; Female; Goats; Lymphocyte Activation; Lymphocytes; Maternal Exposure; Polychlorinated Biphenyls; Pregnancy

2004
Effects of gestational and lactational exposure to low doses of PCBs 126 and 153 on anterior pituitary and gonadal hormones and on puberty in female goats.
    Reproductive toxicology (Elmsford, N.Y.), 2004, Volume: 19, Issue:1

    Topics: Administration, Oral; Animals; Animals, Newborn; Environmental Pollutants; Estrogen Antagonists; Estrous Cycle; Female; Goats; Gonadotropins, Pituitary; Lactation; Male; Maternal Exposure; Maternal-Fetal Exchange; Models, Animal; Pituitary Gland, Anterior; Polychlorinated Biphenyls; Pregnancy; Sexual Maturation

2004
Subchronic exposure to TCDD, PeCDF, PCB126, and PCB153: effect on hepatic gene expression.
    Environmental health perspectives, 2004, Volume: 112, Issue:16

    Topics: Administration, Oral; Animals; Benzofurans; DNA Primers; Female; Gene Expression Profiling; Gene Expression Regulation; Hydrocarbons, Halogenated; Liver; Polychlorinated Biphenyls; Polychlorinated Dibenzodioxins; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA

2004
Polychlorinated biphenyls (PCB 153 and PCB 126) action on conversion of 20-hydroxylated cholesterol to progesterone, androstenedione to testosterone, and testosterone to estradiol 17beta.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2005, Volume: 113, Issue:8

    Topics: Animals; Aromatase; Cells, Cultured; Cholesterol; Estrogen Antagonists; Female; Gonadal Steroid Hormones; Granulosa Cells; Polychlorinated Biphenyls; Swine; Theca Cells

2005
Effects of long-term maternal exposure to low doses of PCB126 and PCB153 on the reproductive system and related hormones of young male goats.
    Reproduction (Cambridge, England), 2005, Volume: 130, Issue:5

    Topics: Androgens; Animals; Chromatin; DNA; Estrogen Antagonists; Female; Fertility; Follicle Stimulating Hormone; Goats; Image Processing, Computer-Assisted; Luteinizing Hormone; Male; Maternal Exposure; Polychlorinated Biphenyls; Pregnancy; Prenatal Exposure Delayed Effects; Spermatogenesis; Spermatozoa; Testis; Testosterone; Time Factors

2005
Effects of single non-ortho, mono-ortho, and di-ortho chlorinated biphenyls on human sperm functions in vitro.
    Reproductive toxicology (Elmsford, N.Y.), 2006, Volume: 21, Issue:3

    Topics: Acrosome Reaction; Environmental Pollutants; Fertilization; Humans; In Vitro Techniques; Male; Polychlorinated Biphenyls; Sperm Motility; Spermatozoa

2006
Perinatal exposure to low doses of PCB 153 and PCB 126 affects maternal and neonatal immunity in goat kids.
    Journal of toxicology and environmental health. Part A, 2006, Jan-08, Volume: 69, Issue:1-2

    Topics: Actinomycetaceae; Animals; Animals, Newborn; Antibodies, Bacterial; Antibodies, Viral; Diphtheria Toxin; Female; Goats; Herpesvirus 1, Equid; Immunization; Immunoglobulin G; Influenza A Virus, H3N8 Subtype; Mannheimia haemolytica; Mycobacterium avium; Orthoreovirus, Mammalian; Polychlorinated Biphenyls; Pregnancy; Prenatal Exposure Delayed Effects; Tetanus Toxin

2006
Apoptosis in bovine cumulus-oocyte complexes after exposure to polychlorinated biphenyl mixtures during in vitro maturation.
    Reproduction (Cambridge, England), 2005, Volume: 130, Issue:6

    Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Cattle; Cells, Cultured; Chlorodiphenyl (54% Chlorine); Dose-Response Relationship, Drug; Drug Combinations; Female; Gene Expression; Genes, bcl-2; In Situ Nick-End Labeling; Oocytes; Oogenesis; Polychlorinated Biphenyls; Polymerase Chain Reaction; RNA, Messenger; Teratogens

2005
Aromatic hydrocarbon receptor (AhR) in the porcine theca and granulosa cells: effect of TCDD, PCB 126 and PCB 153 on the expression of AhR.
    Endocrine regulations, 2005, Volume: 39, Issue:4

    Topics: Animals; Cytoplasm; Environmental Pollutants; Female; Granulosa Cells; Immunoblotting; Immunohistochemistry; Ovary; Polychlorinated Biphenyls; Polychlorinated Dibenzodioxins; Receptors, Aryl Hydrocarbon; Swine; Theca Cells; Tissue Distribution

2005
A physiologically based pharmacokinetic model for lactational transfer of PCB 153 with or without PCB 126 in mice.
    Archives of toxicology, 2007, Volume: 81, Issue:2

    Topics: Animals; Animals, Suckling; Drug Interactions; Drug Therapy, Combination; Environmental Pollutants; Female; Lactation; Lipoproteins, VLDL; Mammary Glands, Animal; Mice; Models, Biological; Polychlorinated Biphenyls; Risk Assessment

2007
Induction of ROS formation, poly(ADP-ribose) polymerase-1 activation, and cell death by PCB126 and PCB153 in human T47D and MDA-MB-231 breast cancer cells.
    Chemico-biological interactions, 2006, Aug-25, Volume: 162, Issue:2

    Topics: Benzoflavones; Breast Neoplasms; Catalase; Cell Line, Tumor; Cell Survival; Chelating Agents; Cytochrome P-450 Enzyme Inhibitors; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Female; Fluoresceins; Humans; Metyrapone; Molecular Structure; NAD; NADP; Oxidation-Reduction; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Polychlorinated Biphenyls; Reactive Oxygen Species; Tamoxifen

2006
Perinatal exposure to PCB 153, but not PCB 126, alters bone tissue composition in female goat offspring.
    Toxicology, 2006, Nov-10, Volume: 228, Issue:1

    Topics: Administration, Oral; Animals; Biomechanical Phenomena; Bone and Bones; Estrogen Antagonists; Female; Goats; Lactation; Maternal Exposure; Polychlorinated Biphenyls; Pregnancy; Prenatal Exposure Delayed Effects; Radiography

2006
Cell death mechanisms in AtT20 pituitary cells exposed to polychlorinated biphenyls (PCB 126 and PCB 153) and methylmercury.
    Toxicology letters, 2006, Dec-15, Volume: 167, Issue:3

    Topics: Animals; Apoptosis; Calcium Signaling; Caspases; Cell Line; Methylmercury Compounds; Mice; Mitochondria; Pituitary Gland; Polychlorinated Biphenyls; Reactive Oxygen Species

2006
Toxicology and carcinogenesis studies of a binary mixture of 3,3',4,4',5-pentachlorobiphenyl (PCB 126) (Cas No. 57465-28-8) and 2,2',4,4',5,5'-hexachlorobiphenyl (PCB 153) (CAS No. 35065-27-1) in female Harlan Sprague-Dawley rats (gavage studies).
    National Toxicology Program technical report series, 2006, Issue:530

    Topics: Animals; Carcinogens; Polychlorinated Biphenyls; Rats; Rats, Sprague-Dawley

2006
Pathways and products of the degradation of PCBs by the sodium dispersion method.
    Chemosphere, 2007, Volume: 68, Issue:5

    Topics: Biphenyl Compounds; Mass Spectrometry; Molecular Structure; Polychlorinated Biphenyls; Sodium; Temperature

2007
An in vitro approach to assess the toxicity of certain food contaminants: methylmercury and polychlorinated biphenyls.
    Toxicology, 2007, Jul-31, Volume: 237, Issue:1-3

    Topics: Animals; Cell Line; Cell Proliferation; Cell Survival; Drug Synergism; Food Contamination; Humans; Methylmercury Compounds; Oxidative Stress; Polychlorinated Biphenyls; Toxicity Tests

2007
Perinatal co-exposure to methylmercury and PCB153 or PCB126 in rats alters the cerebral cholinergic muscarinic receptors at weaning and puberty.
    Toxicology, 2007, Aug-16, Volume: 238, Issue:1

    Topics: Administration, Oral; Animals; Cerebellum; Cerebral Cortex; Dose-Response Relationship, Drug; Female; Immunohistochemistry; Male; Methylmercury Compounds; Polychlorinated Biphenyls; Pregnancy; Prenatal Exposure Delayed Effects; Purkinje Cells; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Sex Factors; Time Factors; Tritium; Weaning; Weight Gain

2007
Developmental exposure to polychlorinated biphenyls PCB153 or PCB126 impairs learning ability in young but not in adult rats.
    The European journal of neuroscience, 2008, Volume: 27, Issue:1

    Topics: Aging; Analysis of Variance; Animals; Animals, Newborn; Behavior, Animal; Cerebellum; Cyclic GMP; Embryo, Mammalian; Female; Glutamic Acid; Learning Disabilities; Maze Learning; Nitric Acid; Polychlorinated Biphenyls; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar

2008
Non-dioxin-like polychlorinated biphenyls induce a release of arachidonic acid in liver epithelial cells: a partial role of cytosolic phospholipase A(2) and extracellular signal-regulated kinases 1/2 signalling.
    Toxicology, 2008, May-02, Volume: 247, Issue:1

    Topics: Animals; Arachidonic Acid; Cell Line; Environmental Pollutants; Epithelial Cells; Liver; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phospholipases A2, Cytosolic; Polychlorinated Biphenyls; Rats; Rats, Inbred F344; Signal Transduction; Stem Cells

2008
Altered stress-induced cortisol levels in goats exposed to polychlorinated biphenyls (PCB 126 and PCB 153) during fetal and postnatal development.
    Journal of toxicology and environmental health. Part A, 2009, Volume: 72, Issue:3-4

    Topics: Administration, Oral; Adrenal Glands; Animals; Dose-Response Relationship, Drug; Female; Goats; Hydrocortisone; Hypothalamo-Hypophyseal System; Lactation; Male; Maternal Exposure; Maternal-Fetal Exchange; Organ Size; Pituitary-Adrenal System; Polychlorinated Biphenyls; Pregnancy; Prenatal Exposure Delayed Effects; Stress, Physiological

2009
Polychlorinated biphenyls PCB 153 and PCB 126 impair the glutamate-nitric oxide-cGMP pathway in cerebellar neurons in culture by different mechanisms.
    Neurotoxicity research, 2009, Volume: 16, Issue:2

    Topics: Animals; Animals, Newborn; Calcium; Cell Survival; Cells, Cultured; Cerebellum; Cyclic GMP; Dose-Response Relationship, Drug; Excitatory Amino Acid Agents; Glutamic Acid; N-Methylaspartate; Neurons; Neurotoxins; Nitric Oxide; Polychlorinated Biphenyls; Rats; Rats, Wistar; Signal Transduction; Time Factors

2009
Reproductive lesions in female Harlan Sprague-Dawley rats following two-year oral treatment with dioxin and dioxin-like compounds.
    Toxicologic pathology, 2009, Volume: 37, Issue:7

    Topics: Administration, Oral; Animals; Benzofurans; Carcinogens; Carcinoma, Squamous Cell; Dioxins; Endometrial Hyperplasia; Female; Metaplasia; Ovary; Polychlorinated Biphenyls; Polychlorinated Dibenzodioxins; Rats; Rats, Sprague-Dawley; Reproduction; Toxicity Tests; Uterine Neoplasms; Uterus

2009
Morphological alterations of Vero cell exposed to coplanar PCB 126 and noncoplanar PCB 153.
    Environmental toxicology, 2012, Volume: 27, Issue:1

    Topics: Animals; Apoptosis; Cell Death; Cell Shape; Environmental Pollutants; Polychlorinated Biphenyls; Vero Cells

2012
Toxicogenomic analysis of exposure to TCDD, PCB126 and PCB153: identification of genomic biomarkers of exposure to AhR ligands.
    BMC genomics, 2010, Oct-19, Volume: 11

    Topics: Animals; Biomarkers; Carcinoma, Hepatocellular; Cholangiocarcinoma; Environmental Exposure; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genome; Ligands; Liver; Liver Neoplasms; Oligonucleotide Array Sequence Analysis; Phenotype; Polychlorinated Biphenyls; Polychlorinated Dibenzodioxins; Rats; Rats, Sprague-Dawley; Receptors, Aryl Hydrocarbon; Toxicogenetics

2010
A new spiked sediment assay using embryos of the Japanese medaka specifically designed for a reliable toxicity assessment of hydrophobic chemicals.
    Aquatic toxicology (Amsterdam, Netherlands), 2011, Volume: 105, Issue:3-4

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Comet Assay; Dose-Response Relationship, Drug; Geologic Sediments; Hydrocarbons, Cyclic; Hydrophobic and Hydrophilic Interactions; Larva; Oryzias; Ovum; Phenols; Polychlorinated Biphenyls; Sensitivity and Specificity; Toxicity Tests; Water Pollutants, Chemical

2011
Gene expression and inducibility of the aryl hydrocarbon receptor-dependent pathway in cultured bovine blood lymphocytes.
    Toxicology letters, 2011, Oct-10, Volume: 206, Issue:2

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzoflavones; Cattle; Cells, Cultured; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; Environmental Pollutants; Enzyme Induction; Enzyme Inhibitors; Gene Expression Regulation; Lymphocyte Activation; Lymphocytes; NAD(P)H Dehydrogenase (Quinone); Polychlorinated Biphenyls; Receptors, Aryl Hydrocarbon; Repressor Proteins; RNA, Messenger; Signal Transduction

2011
Inflammatory pathway genes belong to major targets of persistent organic pollutants in adipose cells.
    Environmental health perspectives, 2012, Volume: 120, Issue:4

    Topics: Adipocytes; Adipose Tissue; Animals; Benzoflavones; Body Weight; Cell Differentiation; Cytokines; Gene Expression Regulation; Humans; Inflammation Mediators; Mice; Mice, Knockout; Multipotent Stem Cells; Obesity; Polychlorinated Biphenyls; Polychlorinated Dibenzodioxins; Real-Time Polymerase Chain Reaction; Receptors, Aryl Hydrocarbon; Reverse Transcriptase Polymerase Chain Reaction; Weight Gain

2012
Synergistic interactions between PBDEs and PCBs in human neuroblastoma cells.
    Environmental toxicology, 2014, Volume: 29, Issue:4

    Topics: Cell Line, Tumor; Drug Synergism; Environmental Pollutants; Halogenated Diphenyl Ethers; Humans; Neuroblastoma; Polychlorinated Biphenyls; Structure-Activity Relationship

2014
Another piece of the obesity-environment puzzle: potential link between inflammation and POP-associated metabolic diseases.
    Environmental health perspectives, 2012, Volume: 120, Issue:4

    Topics: Adipocytes; Animals; Cell Differentiation; Humans; Obesity; Polychlorinated Biphenyls; Polychlorinated Dibenzodioxins

2012
Activation of the Ahr signalling pathway by polychlorobiphenyls causes a marked induction of cytochrome P450 only after depletion of vitellogenin in Sparus aurata.
    Environmental toxicology and pharmacology, 2012, Volume: 34, Issue:3

    Topics: Animals; Biomarkers; Cytochrome P-450 CYP1A1; Endocrine Disruptors; Enzyme Induction; Liver; Polychlorinated Biphenyls; Receptors, Aryl Hydrocarbon; Sea Bream; Vitellogenins; Water Pollutants, Chemical

2012
Gender differential effects of developmental exposure to methyl-mercury, polychlorinated biphenyls 126 or 153, or its combinations on motor activity and coordination.
    Toxicology, 2013, Sep-06, Volume: 311, Issue:1-2

    Topics: Animals; Drug Combinations; Female; Male; Methylmercury Compounds; Motor Activity; Polychlorinated Biphenyls; Psychomotor Performance; Rats; Rats, Wistar; Sex Characteristics

2013
Biological and tumor-promoting effects of dioxin-like and non-dioxin-like polychlorinated biphenyls in mouse liver after single or combined treatment.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 133, Issue:1

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Blotting, Western; Cocarcinogenesis; Cytochrome P-450 CYP1A1; Cytochrome P450 Family 2; Diethylnitrosamine; Dioxins; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Induction; Immunohistochemistry; Liver; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred C3H; Polychlorinated Biphenyls; Steroid Hydroxylases

2013
The effect of PCB126, 77, and 153 on the intracellular mobilization of Ca+2 in bovine granulosa and luteal cells after FSH and LH surge in vitro.
    Polish journal of veterinary sciences, 2013, Volume: 16, Issue:3

    Topics: Animals; Calcium; Cattle; Estrogen Antagonists; Female; Follicle Stimulating Hormone; Granulosa Cells; Luteal Cells; Luteinizing Hormone; Polychlorinated Biphenyls; Time Factors

2013
In vitro effects of TCDD, PCB126 and PCB153 on estrogen receptors, caspases and metalloproteinase-2 mRNA expression in the chicken shell gland.
    Folia biologica, 2013, Volume: 61, Issue:3-4

    Topics: Animal Structures; Animals; Caspases; Chickens; Gene Expression Regulation, Enzymologic; Matrix Metalloproteinase 2; Polychlorinated Biphenyls; Polychlorinated Dibenzodioxins; Receptors, Estrogen; RNA, Messenger

2013
Exposure to the three structurally different PCB congeners (PCB 118, 153, and 126) results in decreased protein expression and altered steroidogenesis in the human adrenocortical carcinoma cell line H295R.
    Journal of toxicology and environmental health. Part A, 2014, Volume: 77, Issue:9-11

    Topics: Adrenocortical Carcinoma; Cell Line, Tumor; Cell Survival; Chromatography, Liquid; Endocrine Disruptors; Estradiol; Gene Expression; Humans; Hydrocortisone; Polychlorinated Biphenyls; Progesterone; Proteome; Steroids; Tandem Mass Spectrometry; Testosterone

2014
The inflammation and estrogen metabolism impacts of polychlorinated biphenyls on endometrial cancer cells.
    Toxicology in vitro : an international journal published in association with BIBRA, 2015, Volume: 29, Issue:2

    Topics: Cell Line, Tumor; Cell Survival; Cytochrome P-450 CYP1A1; Endometrial Neoplasms; Estradiol; Estrogen Antagonists; Estrogens; Female; Humans; Inflammation; Interleukin-8; Polychlorinated Biphenyls; Receptors, Aryl Hydrocarbon; Receptors, Estrogen; RNA, Messenger; Superoxide Dismutase; Superoxide Dismutase-1; Testosterone

2015
Comparison of the in vitro effects of TCDD, PCB 126 and PCB 153 on thyroid-restricted gene expression and thyroid hormone secretion by the chicken thyroid gland.
    Environmental toxicology and pharmacology, 2015, Volume: 39, Issue:2

    Topics: Animals; Chickens; Female; Gene Expression; Iodide Peroxidase; Polychlorinated Biphenyls; Polychlorinated Dibenzodioxins; RNA, Messenger; Symporters; Thyroglobulin; Thyroid Gland; Thyroxine; Triiodothyronine

2015
Divergent Effects of Dioxin- or Non-Dioxin-Like Polychlorinated Biphenyls on the Apoptosis of Primary Cell Culture from the Mouse Pituitary Gland.
    PloS one, 2016, Volume: 11, Issue:1

    Topics: Animals; Annexin A5; Apoptosis; Caspase 8; Caspase 9; Cell Proliferation; Cells, Cultured; Cytochrome P-450 CYP1A1; Dioxins; DNA Fragmentation; Endocrine System; Male; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Phenotype; Pituitary Gland; Polychlorinated Biphenyls; Primary Cell Culture; Receptors, Aryl Hydrocarbon; Receptors, Thyroid Hormone; Signal Transduction

2016
Effects of PCB 126 and PCB 153 on secretion of steroid hormones and mRNA expression of steroidogenic genes (STAR, HSD3B, CYP19A1) and estrogen receptors (ERα, ERβ) in prehierarchical chicken ovarian follicles.
    Toxicology letters, 2016, Dec-15, Volume: 264

    Topics: Animals; Aromatase; Chickens; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Follicular Phase; Gene Expression Regulation, Enzymologic; Ovarian Follicle; Polychlorinated Biphenyls; Progesterone Reductase; RNA, Messenger; Steroids; Testosterone

2016
PCB 126 induces monocyte/macrophage polarization and inflammation through AhR and NF-κB pathways.
    Toxicology and applied pharmacology, 2019, 03-15, Volume: 367

    Topics: Basic Helix-Loop-Helix Transcription Factors; Cell Differentiation; Cytokines; Humans; Inflammation; Inflammation Mediators; Macrophages; NF-kappa B; Phenotype; Polychlorinated Biphenyls; Receptors, Aryl Hydrocarbon; Signal Transduction; THP-1 Cells

2019
Polychlorinated biphenyls promote cell survival through pyruvate kinase M2-dependent glycolysis in HeLa cells.
    Toxicology mechanisms and methods, 2019, Volume: 29, Issue:6

    Topics: Cell Survival; Environmental Pollutants; Glycolysis; HeLa Cells; Humans; NADPH Oxidases; Polychlorinated Biphenyls; Pyruvate Kinase; Reactive Oxygen Species; Up-Regulation

2019
Metabolic impact of persistent organic pollutants on gut microbiota.
    Gut microbes, 2020, 11-09, Volume: 12, Issue:1

    Topics: Animals; Bacteria; Benzofurans; Carbon; Cecum; Citric Acid Cycle; Gastrointestinal Microbiome; Lipid Metabolism; Male; Mice; Mice, Inbred C57BL; Persistent Organic Pollutants; Polychlorinated Biphenyls; Polychlorinated Dibenzodioxins; Protein Transport; Pyruvic Acid

2020
Effect of exposure to 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) and polychlorinated biphenyls (PCBs) on mitochondrial DNA (mtDNA) copy number in rats.
    Toxicology, 2021, 04-30, Volume: 454

    Topics: Animals; DNA Copy Number Variations; DNA, Mitochondrial; Dose-Response Relationship, Drug; Female; Liver; Lung; Oxidative Stress; Polychlorinated Biphenyls; Polychlorinated Dibenzodioxins; Rats; Rats, Sprague-Dawley

2021