Compounds > 2,4,5,2',4',5'-hexachlorobiphenyl
Page last updated: 2024-08-23

2,4,5,2',4',5'-hexachlorobiphenyl and 3,4,3',4'-tetrachlorobiphenyl

2,4,5,2',4',5'-hexachlorobiphenyl has been researched along with 3,4,3',4'-tetrachlorobiphenyl in 36 studies

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-19904 (11.11)18.7374
1990's7 (19.44)18.2507
2000's17 (47.22)29.6817
2010's7 (19.44)24.3611
2020's1 (2.78)2.80

Authors

AuthorsStudies
Karplus, M; So, SS1
Edwards, BC; Fisher, HL; Goodwin, JH; Hall, LL; Hughes, MF; Shah, PV; Shrivastava, SP; Sumler, MR1
Borlakoglu, JT; Clarke, S; Dils, RR; Gibson, GG; Haegele, KD; Huang, SW1
Buchmann, A; Kunz, W; Oesch, F; Robertson, LW; Wolf, CR1
Cameron, RG; Farber, E; Hayes, MA; Roberts, E; Roomi, MW; Safe, SH1
Cameron, RC; Farber, E; Hayes, MA; Jago, MV; Roberts, E; Safe, SH1
Greenlee, WF; Irons, RD1
Berberian, I; Chen, LC; Chow, CK; Glauert, HP; Robertson, LW; Robinson, FR1
Brown, MM; Bunce, NJ; Petrulis, JR; Schneider, UA1
Borlakoglu, JT; Henderson, CJ; Wolf, CR1
Dietrich, D; Hickey, WJ; Lamar, R1
Bunce, NJ; Petrulis, JR1
Fernández Santiago, M; López-Aparicio, P; Pérez-Albarsanz, MA; Recio, MN; Sánchez, E1
Glauert, HP; Larmonier, N; O'Brien, ML; Robertson, LW; Twaroski, TP1
López-Aparicio, P; Pérez-Albarsanz, MA; Recio, MN; Santiago, MF1
O'Brien, ML; Robertson, LW; Twaroski, TP1
Glauert, HP; Lee, EY; Robertson, LW; Spear, BT; Tharappel, JC1
Fadhel, Z; Glauert, HP; Lu, Z; Robertson, LW1
López-Aparicio, P; Pérez-Albarsanz, MA; Recio, MN; Sánchez-Alonso, JA1
Beck, V; Covaci, A; Darras, VM; Geuns, JM; Maervoet, J; Roelens, SA; Schepens, P; Voorspoels, S1
Gossiaux, DC; Gunnarsson, J; Kukkonen, JV; Landrum, PF; Mitra, S; Weston, D1
Aerts, G; Beck, V; Darras, VM; Maervoet, J; Reyns, GE; Roelens, SA; Schepens, P1
López-Aparicio, P; Pérez-Albarsanz, MA; Pérez-Reyes, PL; Recio, MN; Santiago, MF1
Fischer, B; Nestler, D; Pocar, P; Risch, M1
Khan, IA; Thomas, P1
Bunaciu, RP; Glauert, HP; Kania-Korwel, I; Lehmler, HJ; Robertson, LW; Spear, BT; Srinivasan, C; Tharappel, JC1
Glauert, HP; Lehmler, HJ; Morris, JS; Robertson, LW; Spate, VL; Spear, BT; Srinivasan, C; Stemm, DN; Tharappel, JC1
Arsenescu, RI; Arsenescu, V; Cassis, LA; King, V; Swanson, H1
Chatterjee, R; Chen, YQ; De, S; Dutta, SK; Ghosh, S; Hoffman, EP; Kesari, A; Moses, L1
Ayorinde, FO; Chen, Y; De, S; Dutta, SK; Ghosh, S; Sutton, DC1
Akkanen, J; Kukkonen, JV; Lydy, MJ; Pehkonen, S; You, J1
Carletti, M; Girolami, F; Nebbia, C; Perona, G; Rasero, R; Sacchi, P; Spalenza, V1
Batal, M; Blais, JM; Casimiro, C; Chapados, NA; Haman, F; Imbeault, P; Robidoux, MA1
Kowalik, M; Mlynarczuk, J1
Bogazzi, F; Cappellani, D; Lupi, I; Manetti, L; Marcocci, C; Martino, E; Raggi, F; Russo, D; Sardella, C; Tomisti, L; Urbani, C1
Kmetič, I; Kovač, V; Miletić, M; Murati, T; Petković, T; Pleadin, J; Šimić, B; Štrac, DŠ1

Other Studies

36 other study(ies) available for 2,4,5,2',4',5'-hexachlorobiphenyl and 3,4,3',4'-tetrachlorobiphenyl

ArticleYear
Three-dimensional quantitative structure-activity relationships from molecular similarity matrices and genetic neural networks. 2. Applications.
    Journal of medicinal chemistry, 1997, Dec-19, Volume: 40, Issue:26

    Topics: Cholinesterase Inhibitors; Dopamine beta-Hydroxylase; Drug Design; Enzyme Inhibitors; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Molecular Conformation; Molecular Structure; Neural Networks, Computer; Phosphorylases; Receptors, Aryl Hydrocarbon; Static Electricity; Structure-Activity Relationship

1997
Dermal absorption of chemicals: effect of application of chemicals as a solid, aqueous paste, suspension, or in volatile vehicle.
    Journal of toxicology and environmental health, 1992, Volume: 37, Issue:1

    Topics: 2,4-Dinitrophenol; Administration, Cutaneous; Animals; Dinitrophenols; Ethanol; Female; Ointments; Pesticides; Polychlorinated Biphenyls; Rats; Rats, Inbred F344; Skin Absorption; Suspensions; Tissue Distribution

1992
Lactational transfer of 3,3',4,4'-tetrachloro- and 2,2',4,4',5,5'-hexachlorobiphenyl induces cytochrome P450IVA1 in neonates. Evidence for a potential synergistic mechanism.
    Biochemical pharmacology, 1992, Jan-22, Volume: 43, Issue:2

    Topics: Animals; Animals, Newborn; Biological Transport; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme System; Cytochromes b5; Enzyme Induction; Female; Lactation; Microsomes, Liver; Mixed Function Oxygenases; Polychlorinated Biphenyls; Rats

1992
Polychlorinated biphenyls, classified as either phenobarbital- or 3-methylcholanthrene-type inducers of cytochrome P-450, are both hepatic tumor promoters in diethylnitrosamine-initiated rats.
    Cancer letters, 1986, Volume: 32, Issue:3

    Topics: Animals; Cocarcinogenesis; Cytochrome P-450 Enzyme System; Diethylnitrosamine; Enzyme Induction; Female; Isoenzymes; Liver; Liver Neoplasms, Experimental; Methylcholanthrene; Phenobarbital; Polychlorinated Biphenyls; Rats

1986
Comparative influences of different PB-type and 3-MC-type polychlorinated biphenyl-induced phenotypes on cytocidal hepatotoxicity of bromobenzene and acetaminophen.
    Toxicology and applied pharmacology, 1984, Volume: 76, Issue:1

    Topics: Acetaminophen; Animals; Bromobenzenes; Cells, Cultured; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Drug Interactions; L-Lactate Dehydrogenase; Liver; Male; Polychlorinated Biphenyls; Rats; Rats, Inbred F344

1984
Influences of various xenobiotic inducers on cytocidal toxicity of lasiocarpine and senecionine in primary cultures of rat hepatocytes.
    Journal of toxicology and environmental health, 1984, Volume: 14, Issue:5-6

    Topics: Animals; Carcinogens; Cells, Cultured; Cytochrome P-450 Enzyme System; Enzyme Induction; Liver; Male; Methylcholanthrene; Phenobarbital; Polychlorinated Biphenyls; Proadifen; Pyrrolizidine Alkaloids; Rats; Rats, Inbred F344

1984
Modulation of benzene-induced lymphocytopenia in the rat by 2,4,5,2',4',5'-hexachlorobiphenyl and 3,4,3',4'-tetrachlorobiphenyl.
    Chemico-biological interactions, 1981, Volume: 33, Issue:2-3

    Topics: Animals; Benzene; In Vitro Techniques; Liver; Lymphopenia; Male; Polychlorinated Biphenyls; Rats; Rats, Inbred F344; Time Factors

1981
Effect of dietary retinyl palmitate on the promotion of altered hepatic foci by 3,3',4,4'-tetrachlorobiphenyl and 2,2',4,4',5,5'-hexachlorobiphenyl in rats initiated with diethylnitrosamine.
    Carcinogenesis, 1995, Volume: 16, Issue:2

    Topics: Animals; Body Weight; Cell Division; Cocarcinogenesis; Diethylnitrosamine; Diterpenes; Drug Interactions; Female; Liver; Liver Neoplasms, Experimental; Methylcholanthrene; Polychlorinated Biphenyls; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Retinyl Esters; Vitamin A

1995
Additive binding of polychlorinated biphenyls and 2,3,7,8-tetrachlorodibenzo-p-dioxin to the murine hepatic Ah receptor.
    Toxicology and applied pharmacology, 1994, Volume: 129, Issue:2

    Topics: Animals; Binding, Competitive; Cytosol; In Vitro Techniques; Liver; Male; Mice; Mice, Inbred C57BL; Polychlorinated Biphenyls; Polychlorinated Dibenzodioxins; Receptors, Aryl Hydrocarbon; Structure-Activity Relationship

1994
Lactational transfer of 2,4,5,2',4',5'-hexachlorobiphenyl but not 3,4,3',4'-tetrachlorobiphenyl, induces neonatal CYP4A1.
    Biochemical pharmacology, 1993, Feb-09, Volume: 45, Issue:3

    Topics: Animals; Animals, Newborn; Aroclors; Chlorodiphenyl (54% Chlorine); Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Isoenzymes; Lactation; Polychlorinated Biphenyls; Rats; Rats, Sprague-Dawley

1993
Degradation of 4,4'-dichlorobiphenyl, 3,3',4,4'-tetrachlorobiphenyl, and 2,2',4,4',5,5'-hexachlorobiphenyl by the white rot fungus Phanerochaete chrysosporium.
    Applied and environmental microbiology, 1995, Volume: 61, Issue:11

    Topics: Basidiomycota; Biodegradation, Environmental; Environmental Pollutants; Kinetics; Mass Spectrometry; Minerals; Polychlorinated Biphenyls; Xenobiotics

1995
Competitive behavior in the interactive toxicology of halogenated aromatic compounds.
    Journal of biochemical and molecular toxicology, 2000, Volume: 14, Issue:2

    Topics: Animals; Cytochrome P-450 CYP1A1; Enzyme Induction; Guinea Pigs; Liver; Male; Mice; Polychlorinated Biphenyls; Polychlorinated Dibenzodioxins; Rats; Rats, Sprague-Dawley; Receptors, Aryl Hydrocarbon

2000
Selective fatty acid release from intracellular phospholipids caused by PCBs in rat renal tubular cell cultures.
    Chemico-biological interactions, 2000, Mar-01, Volume: 125, Issue:2

    Topics: Animals; Aroclors; Cells, Cultured; Dose-Response Relationship, Drug; Fatty Acids, Monounsaturated; Fatty Acids, Nonesterified; Intracellular Fluid; Kidney Tubules, Proximal; Oleic Acid; Palmitic Acid; Phospholipids; Polychlorinated Biphenyls; Rats; Triglycerides

2000
Polychlorinated biphenyl-induced effects on metabolic enzymes, AP-1 binding, vitamin E, and oxidative stress in the rat liver.
    Toxicology and applied pharmacology, 2001, Mar-01, Volume: 171, Issue:2

    Topics: Animals; Cell Nucleus; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A1; DNA; Environmental Pollutants; Female; Gas Chromatography-Mass Spectrometry; Liver; Male; Microsomes, Liver; NAD(P)H Dehydrogenase (Quinone); Organ Size; Oxidative Stress; Polychlorinated Biphenyls; Rats; Rats, Sprague-Dawley; Transcription Factor AP-1; Vitamin E

2001
Redistribution of cPLA(2) in rat renal tubular cell cultures in response to PCBs.
    Cellular signalling, 2001, Volume: 13, Issue:2

    Topics: Animals; Anisomycin; Aroclors; Cells, Cultured; Cytosol; Dactinomycin; Dose-Response Relationship, Drug; Fungicides, Industrial; Immunoblotting; Kidney; Kidney Tubules; Phospholipases A; Polychlorinated Biphenyls; Protein Isoforms; Protein Synthesis Inhibitors; Rats; Subcellular Fractions; Tissue Distribution

2001
Effects of selected polychlorinated biphenyl (PCB) congeners on hepatic glutathione, glutathione-related enzymes, and selenium status: implications for oxidative stress.
    Biochemical pharmacology, 2001, Aug-01, Volume: 62, Issue:3

    Topics: Analysis of Variance; Animals; Female; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Liver; Male; Oxidative Stress; Polychlorinated Biphenyls; Rats; Rats, Sprague-Dawley; Selenium

2001
Regulation of cell proliferation, apoptosis, and transcription factor activities during the promotion of liver carcinogenesis by polychlorinated biphenyls.
    Toxicology and applied pharmacology, 2002, Mar-15, Volume: 179, Issue:3

    Topics: Animals; Apoptosis; Cell Division; Diethylnitrosamine; DNA-Binding Proteins; Electrophoretic Mobility Shift Assay; Female; Immunoblotting; In Situ Nick-End Labeling; Liver Neoplasms, Experimental; Milk Proteins; NF-kappa B; Oxidative Stress; Polychlorinated Biphenyls; Rats; Rats, Sprague-Dawley; STAT3 Transcription Factor; STAT5 Transcription Factor; Trans-Activators; Transcription Factor AP-1; Transcription Factors

2002
Effect of 3,3',4,4'-tetrachlorobiphenyl and 2,2',4,4',5,5'-hexachlorobiphenyl on the induction of hepatic lipid peroxidation and cytochrome P-450 associated enzyme activities in rats.
    Toxicology, 2002, Jun-14, Volume: 175, Issue:1-3

    Topics: Animals; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Lipid Peroxidation; Lipid Peroxides; Liver; Male; Microsomes, Liver; Oxidoreductases; Polychlorinated Biphenyls; Rats; Rats, Sprague-Dawley; Thiobarbituric Acid Reactive Substances

2002
Apoptosis-mediated neurotoxic potential of a planar (PCB 77) and a nonplanar (PCB 153) polychlorinated biphenyl congeners in neuronal cell cultures.
    Toxicology letters, 2003, Oct-15, Volume: 144, Issue:3

    Topics: Animals; Apoptosis; Caspase 3; Caspases; Cell Culture Techniques; Cell Survival; Cerebral Cortex; Environmental Pollutants; Neurons; Polychlorinated Biphenyls; Rats; Rats, Wistar; Structure-Activity Relationship

2003
Uptake and tissue-specific distribution of selected polychlorinated biphenyls in developing chicken embryos.
    Environmental toxicology and chemistry, 2005, Volume: 24, Issue:3

    Topics: Animals; Brain; Chick Embryo; Egg Yolk; Environmental Pollutants; Lipids; Liver; Polychlorinated Biphenyls; Tissue Distribution

2005
The contrasting roles of sedimentary plant-derived carbon and black carbon on sediment-spiked hydrophobic organic contaminant bioavailability to Diporeia species and Lumbriculus variegatus.
    Environmental toxicology and chemistry, 2005, Volume: 24, Issue:4

    Topics: Adsorption; Animals; Benzo(a)pyrene; Biodiversity; Biological Availability; Carbon; Crustacea; Environmental Pollutants; Geologic Sediments; Hydrophobic and Hydrophilic Interactions; Oligochaeta; Polychlorinated Biphenyls; Pyrenes; Species Specificity; Time Factors

2005
The dioxin-like PCB 77 but not the ortho-substituted PCB 153 interferes with chicken embryo thyroid hormone homeostasis and delays hatching.
    General and comparative endocrinology, 2005, Volume: 143, Issue:1

    Topics: Animals; Chick Embryo; Polychlorinated Biphenyls; Thyroxine; Time Factors; Triiodothyronine

2005
Differential effects of PCBs on the induction of apoptosis machinery and PKCalpha translocation in rat renal tubular cell cultures.
    Toxicology letters, 2006, May-25, Volume: 163, Issue:2

    Topics: Animals; Apoptosis; Aroclors; bcl-2-Associated X Protein; Caspase 3; Caspases; Cell Fractionation; Cell Survival; Cells, Cultured; Cytosol; Dose-Response Relationship, Drug; Environmental Pollutants; Enzyme Induction; Kidney Tubules; Polychlorinated Biphenyls; Protein Kinase C-alpha; Proto-Oncogene Proteins c-bcl-2; Rats

2006
Apoptosis in bovine cumulus-oocyte complexes after exposure to polychlorinated biphenyl mixtures during in vitro maturation.
    Reproduction (Cambridge, England), 2005, Volume: 130, Issue:6

    Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Cattle; Cells, Cultured; Chlorodiphenyl (54% Chlorine); Dose-Response Relationship, Drug; Drug Combinations; Female; Gene Expression; Genes, bcl-2; In Situ Nick-End Labeling; Oocytes; Oogenesis; Polychlorinated Biphenyls; Polymerase Chain Reaction; RNA, Messenger; Teratogens

2005
PCB congener-specific disruption of reproductive neuroendocrine function in Atlantic croaker.
    Marine environmental research, 2006, Volume: 62 Suppl

    Topics: Animals; Chlorodiphenyl (54% Chlorine); Environmental Exposure; Gonads; Male; Neurosecretory Systems; Perciformes; Polychlorinated Biphenyls; Reproduction; Tryptophan Hydroxylase; Water Pollutants, Chemical

2006
The effect of dietary glycine on the hepatic tumor promoting activity of polychlorinated biphenyls (PCBs) in rats.
    Toxicology, 2007, Oct-08, Volume: 239, Issue:3

    Topics: Administration, Oral; Alkylating Agents; Animals; Body Weight; Carcinogens, Environmental; Cell Proliferation; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2B1; Diet; Diethylnitrosamine; Female; Glutathione Transferase; Glycine; Hepatocytes; Immunohistochemistry; Injections, Intraperitoneal; Liver; Organ Size; Polychlorinated Biphenyls; Precancerous Conditions; Rats; Rats, Sprague-Dawley

2007
Effect of dietary selenium on the promotion of hepatocarcinogenesis by 3,3', 4,4'-tetrachlorobiphenyl and 2,2', 4,4', 5,5'-hexachlorobiphenyl.
    Experimental biology and medicine (Maywood, N.J.), 2008, Volume: 233, Issue:3

    Topics: Animal Feed; Animals; Body Weight; Cell Proliferation; Cell Transformation, Neoplastic; Female; Glutathione Peroxidase; Liver Neoplasms; Organ Size; Polychlorinated Biphenyls; Rats; Rats, Sprague-Dawley; Selenium; Thioredoxin-Disulfide Reductase

2008
Polychlorinated biphenyl-77 induces adipocyte differentiation and proinflammatory adipokines and promotes obesity and atherosclerosis.
    Environmental health perspectives, 2008, Volume: 116, Issue:6

    Topics: 3T3-L1 Cells; Adipocytes; Adipokines; Animals; Atherosclerosis; Body Weight; Cell Differentiation; Cytokines; Gene Expression; Glycerolphosphate Dehydrogenase; Inflammation Mediators; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Obesity; Polychlorinated Biphenyls; PPAR gamma; Receptors, Aryl Hydrocarbon; Reverse Transcriptase Polymerase Chain Reaction; Weight Gain

2008
PCB congener specific oxidative stress response by microarray analysis using human liver cell line.
    Environment international, 2010, Volume: 36, Issue:8

    Topics: Apoptosis; Cell Line; Gene Expression Profiling; Hepatocytes; Humans; Microarray Analysis; Microscopy, Fluorescence; Mutagens; Oxidants; Oxidative Stress; Paraquat; Polychlorinated Biphenyls; Reverse Transcriptase Polymerase Chain Reaction

2010
Polychlorinated biphenyls (PCB-153) and (PCB-77) absorption in human liver (HepG2) and kidney (HK2) cells in vitro: PCB levels and cell death.
    Environment international, 2010, Volume: 36, Issue:8

    Topics: Cell Death; Cell Line; Cell Survival; Culture Media, Serum-Free; DNA Fragmentation; Environmental Pollutants; Hepatocytes; Humans; Lethal Dose 50; Mutagens; Polychlorinated Biphenyls; Trypan Blue

2010
Influence of black carbon and chemical planarity on bioavailability of sediment-associated contaminants.
    Environmental toxicology and chemistry, 2010, Volume: 29, Issue:9

    Topics: Animals; Benzo(a)pyrene; Geologic Sediments; Oligochaeta; Permethrin; Polychlorinated Biphenyls; Soot; Water Pollutants, Chemical

2010
Gene expression and inducibility of the aryl hydrocarbon receptor-dependent pathway in cultured bovine blood lymphocytes.
    Toxicology letters, 2011, Oct-10, Volume: 206, Issue:2

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzoflavones; Cattle; Cells, Cultured; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; Environmental Pollutants; Enzyme Induction; Enzyme Inhibitors; Gene Expression Regulation; Lymphocyte Activation; Lymphocytes; NAD(P)H Dehydrogenase (Quinone); Polychlorinated Biphenyls; Receptors, Aryl Hydrocarbon; Repressor Proteins; RNA, Messenger; Signal Transduction

2011
Increased proliferative effect of organochlorine compounds on human preadipocytes.
    Molecular and cellular biochemistry, 2012, Volume: 365, Issue:1-2

    Topics: Adipocytes, White; Cell Proliferation; Dichlorodiphenyl Dichloroethylene; Environmental Pollutants; Humans; Hydrocarbons, Chlorinated; Insecticides; Polychlorinated Biphenyls; Subcutaneous Fat

2012
The effect of PCB126, 77, and 153 on the intracellular mobilization of Ca+2 in bovine granulosa and luteal cells after FSH and LH surge in vitro.
    Polish journal of veterinary sciences, 2013, Volume: 16, Issue:3

    Topics: Animals; Calcium; Cattle; Estrogen Antagonists; Female; Follicle Stimulating Hormone; Granulosa Cells; Luteal Cells; Luteinizing Hormone; Polychlorinated Biphenyls; Time Factors

2013
Divergent Effects of Dioxin- or Non-Dioxin-Like Polychlorinated Biphenyls on the Apoptosis of Primary Cell Culture from the Mouse Pituitary Gland.
    PloS one, 2016, Volume: 11, Issue:1

    Topics: Animals; Annexin A5; Apoptosis; Caspase 8; Caspase 9; Cell Proliferation; Cells, Cultured; Cytochrome P-450 CYP1A1; Dioxins; DNA Fragmentation; Endocrine System; Male; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Phenotype; Pituitary Gland; Polychlorinated Biphenyls; Primary Cell Culture; Receptors, Aryl Hydrocarbon; Receptors, Thyroid Hormone; Signal Transduction

2016
Resveratrol ameliorates ortho- polychlorinated biphenyls' induced toxicity in ovary cells.
    Environmental science and pollution research international, 2023, Volume: 30, Issue:31

    Topics: Diabetes Mellitus, Type 2; Female; Humans; Ovary; Polychlorinated Biphenyls; Resveratrol

2023