2-4-4--trihydroxydeoxybenzoin has been researched along with kojic-acid* in 1 studies
1 other study(ies) available for 2-4-4--trihydroxydeoxybenzoin and kojic-acid
Article | Year |
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Design, synthesis and molecular simulation studies of dihydrostilbene derivatives as potent tyrosinase inhibitors.
The synthesis, molecular modeling and biological evaluation of substituted deoxybenzoins and optimized dihydrostilbenes are reported. Preliminary structure-activity relationship data were elucidated and lead compounds suitable for further optimization were discovered. Dihydrostilbene 7 is a particularly potent inhibitor (IC(50)=8.44 μM, more potent than kojic acid). Topics: Bacteria; Benzoin; Drug Design; Enzyme Inhibitors; Fungi; Molecular Docking Simulation; Monophenol Monooxygenase; Pyrones; Stilbenes; Structure-Activity Relationship | 2012 |