2,3-trimethylene-4-quinazolone has been researched along with tacrine in 4 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 2 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gu, LQ; Hou, JQ; Huang, SL; Huang, ZS; Pan, L; Tan, JH | 1 |
| Du, H; Ma, F | 1 |
| Du, H; Jiang, X; Liu, S; Ma, F; Ma, M; Xu, H | 1 |
| Jeripothula, M; Nerella, A | 1 |
4 other study(ies) available for 2,3-trimethylene-4-quinazolone and tacrine
| Article | Year |
|---|---|
Design, synthesis and evaluation of isaindigotone derivatives as acetylcholinesterase and butyrylcholinesterase inhibitors.
Topics: Acetylcholinesterase; Alkaloids; Binding Sites; Butyrylcholinesterase; Chemistry, Pharmaceutical; Cholinesterase Inhibitors; Drug Design; Enzyme Inhibitors; Humans; Models, Chemical; Molecular Conformation; Molecular Structure; Quinazolines; Structure-Activity Relationship | 2008 |
Novel deoxyvasicinone derivatives as potent multitarget-directed ligands for the treatment of Alzheimer's disease: Design, synthesis, and biological evaluation.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Butyrylcholinesterase; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Design; Humans; Kinetics; Ligands; Molecular Structure; Peptide Fragments; Protein Aggregates; Quinazolines; Structure-Activity Relationship | 2017 |
Novel deoxyvasicinone and tetrahydro-beta-carboline hybrids as inhibitors of acetylcholinesterase and amyloid beta aggregation.
Topics: Acetylcholinesterase; Alkaloids; Alzheimer Disease; Amyloid beta-Peptides; Carbolines; Cell Line; Cholinesterase Inhibitors; Humans; Molecular Docking Simulation; Peptide Fragments; Protein Aggregates; Protein Aggregation, Pathological | 2020 |
Design, synthesis and biological evaluation of novel deoxyvasicinone-indole as multi-target agents for Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Butyrylcholinesterase; Catalytic Domain; Cell Line, Tumor; Cholinesterase Inhibitors; Drug Design; Electrophorus; Horses; Indoles; Kinetics; Mice; Molecular Docking Simulation; Neuroprotective Agents; Peptide Fragments; Protein Binding; Protein Multimerization; Quinazolines; Rats | 2021 |