Page last updated: 2024-08-21

2,3-pentanedione and diacetyl

2,3-pentanedione has been researched along with diacetyl in 45 studies

Research

Studies (45)

Timeframe	Studies, this research(%)	All Research%
pre-1990	7 (15.56)	18.7374
1990's	1 (2.22)	18.2507
2000's	3 (6.67)	29.6817
2010's	27 (60.00)	24.3611
2020's	7 (15.56)	2.80

Authors

Authors	Studies
Beroza, P; Damodaran, K; Danks, MK; Edwards, CC; Hyatt, JL; Morton, CL; Obenauer, JC; Potter, PM; Wadkins, RM; Wei, X; Wierdl, M; Yoon, KJ	1
Güvenc, U; Postel, W	1
Dekker, EE; Epperly, BR	1
Gjermansen, C; Holmberg, S; Kielland-Brandt, MC; Nilsson-Tillgren, T; Petersen, JG; Sigsgaard, P	1
Bernardo, A; González, J; Martin, R; Vidal, I	1
Burgos, J; González Prieto, J; Martín Sarmiento, R	1
Chang, GG; Huang, TM	1
Choi, JD; McCormick, DB	1
Keyhani, A; Yaylayan, VA	1
Chaintreau, A; Germond, JE; Ott, A	1
Avery, L; Kim, K; Sengupta, P; van der Linden, AM; Wiener, S; You, YJ	1
Battelli, LA; Castranova, V; Cumpston, AM; Fedan, JS; Fluharty, KL; Frazer, DG; Friend, S; Goldsmith, WT; Goravanahally, MP; Hubbs, AF; Jackson, MC; Kashon, ML; Kreiss, K; Schwegler-Berry, D; Sriram, K; Willard, PA	1
Kusunoki, K; Ogata, T	1
Potera, C	1
Gibson, BR; Krogerus, K	1
Cumpston, AM; Fedan, JS; Frazer, DG; Goldsmith, WT; Hubbs, AF; Jackson, MC; Kashon, ML; Ponnoth, DS; Shimko, MJ; Thompson, JA; Zaccone, EJ	1
Anderson, SE; Franko, J; Lukomska, E; Meade, BJ; Wells, JR	1
Abelmann, A; Adams, RE; Finley, BL; Pierce, JS; Spicer, LJ	1
Farsalinos, KE; Gillman, G; Kistler, KA; Voudris, V	1
Finley, BL; Kerger, BD; Thuett, KA	1
Leça, JM; Marques, JC; Pereira, AC; Reis, MS; Vieira, AC	1
Case, SL; Fedan, JS; Goldsmith, WT; Schwegler-Berry, D; Shimko, MJ; Thompson, JA; Wells, JR; Willard, PA; Zaccone, EJ	1
Bailey, RL; Bledsoe, TA; Cox-Ganser, JM; Duling, MG; Green, BJ; Kreiss, K; LeBouf, RF; Martin, SB	1
Allen, JG; Christiani, DC; Flanigan, SS; LeBlanc, M; MacNaughton, P; Stewart, JH; Vallarino, J	2
Hines, SE; Holden, VK	1
Bousquet, RW; Flake, GP; Gwinn, WM; Johnson, CL; Jokinen, MP; Morgan, DL; Price, HC	1
Bailey, RL; Cox-Ganser, JM; Duling, MG; Kreiss, K; LeBouf, RF; Martin, SB	1
Abelmann, A; Finley, BL; Pierce, JS	1
Blanchette, M; Cyr, N; Jardim, A; Sheppard, JD; Strasser, R; van Bergen, B	1
LeBouf, R; Simmons, M	1
Flake, GP; Morgan, DL	1
Laws, J	1
Cummings, KJ; Hawley, B; LeBouf, RF	1
Coggins, MA; O'Shea, H; Pengelly, I; Smith, G	1
Brown, VM; Pengelly, I	1
McAdam, K; Porter, A; Vas, CA	1
Battelli, LA; Clingerman, SM; Cole, A; Cummings, KJ; Cumpston, A; Dodd, TM; Fedan, JS; Flesher, JR; Fluharty, KL; Hubbs, AF; Jackson, M; Kashon, M; Kreiss, K; Lee, R; O'Connell, R; Orandle, MS; Pagel, S; Sriram, K	1
Marques, JC; Pereira, AC; Reis, MS; Vieira, AC	1
Bailey, RL; Blackley, BH; Burns, DA; Cox-Ganser, JM; Cummings, KJ; Duling, MG; Edwards, N; Fedan, KB; Fortner, AR; Groth, CP; LeBouf, RF; Martin, SB; McClelland, TL; Nett, RJ; Ranpara, A; Stanton, M; Virji, MA	1
Burns, DA; Fernandez, E; Fortner, AR; LeBouf, RF; Ranpara, A	1
Beaty, M; Martin, SB; McClelland, TL; Ranpara, A; Stanton, ML	1
Cox-Ganser, JM; Johns, DO; Whittaker, C	1
Card, JW; Haighton, LA; Scaife, KM	1

Reviews

4 review(s) available for 2,3-pentanedione and diacetyl

Article	Year
Diacetyl and 2,3-pentanedione exposures associated with cigarette smoking: implications for risk assessment of food and flavoring workers. Critical reviews in toxicology, 2014, Volume: 44, Issue:5 Topics: Animals; Bronchiolitis Obliterans; Canada; Diacetyl; Disease Models, Animal; Evaluation Studies as Topic; Flavoring Agents; Food-Processing Industry; Humans; Inhalation Exposure; Occupational Exposure; Pentanones; Risk Assessment; Smoking	2014
Update on flavoring-induced lung disease. Current opinion in pulmonary medicine, 2016, Volume: 22, Issue:2 Topics: Animals; Diacetyl; Flavoring Agents; Humans; Lung Diseases; Pentanones; Risk	2016
Flavorings-Related Lung Disease: A Brief Review and New Mechanistic Data. Toxicologic pathology, 2019, Volume: 47, Issue:8 Topics: Acetoin; Air Pollutants, Occupational; Bronchiolitis Obliterans; Diacetyl; Flavoring Agents; Humans; Inhalation Exposure; Lung Diseases; Occupational Diseases; Occupational Exposure; Pentanones	2019
Review of evidence relating to occupational exposure limits for alpha-diketones and acetoin, and considerations for deriving an occupational exposure limit for 2,3-pentanedione. Critical reviews in toxicology, 2022, Volume: 52, Issue:9 Topics: Acetoin; Diacetyl; Ketones; Occupational Exposure; Pentanones	2022

Other Studies

41 other study(ies) available for 2,3-pentanedione and diacetyl

Article	Year
Identification and characterization of novel benzil (diphenylethane-1,2-dione) analogues as inhibitors of mammalian carboxylesterases. Journal of medicinal chemistry, 2005, Apr-21, Volume: 48, Issue:8 Topics: Acetylcholinesterase; Animals; Butyrylcholinesterase; Carboxylesterase; Carboxylic Ester Hydrolases; Cholinesterase Inhibitors; Databases, Factual; Humans; Intestines; Models, Molecular; Phenylglyoxal; Quantitative Structure-Activity Relationship; Rats; Structure-Activity Relationship; Umbelliferones	2005
[Gaschromatographical determination of diacetyl, acetoin, and 2,3-pentanedione in wine (author's transl)]. Zeitschrift fur Lebensmittel-Untersuchung und -Forschung, 1976, Volume: 161, Issue:1 Topics: Acetoin; Butanones; Chromatography, Gas; Color; Diacetyl; Ketones; Pentanones; Photometry; Wine	1976
Inactivation of Escherichia coli L-threonine dehydrogenase by 2,3-butanedione. Evidence for a catalytically essential arginine residue. The Journal of biological chemistry, 1989, Nov-05, Volume: 264, Issue:31 Topics: Alcohol Oxidoreductases; Arginine; Binding Sites; Butanones; Catalysis; Cyclohexanones; Diacetyl; Escherichia coli; Kinetics; NAD; Pentanones; Phenylglyoxal	1989
Towards diacetyl-less brewers' yeast. Influence of ilv2 and ilv5 mutations. Journal of basic microbiology, 1988, Volume: 28, Issue:3 Topics: Acetolactate Synthase; Butanones; Chromosome Mapping; Diacetyl; Genes, Fungal; Isoleucine; Lactates; Mutation; Pentanones; Saccharomyces; Saccharomyces cerevisiae; Valine	1988
Kinetics of the diacetyl and 2,3-pentanedione reduction by diacetyl reductase (alpha-diketone reductase (NAD)) from Staphylococcus aureus. Biochimie, 1988, Volume: 70, Issue:12 Topics: Acetoin Dehydrogenase; Alcohol Oxidoreductases; Allosteric Regulation; Butanones; Diacetyl; Ketones; Kinetics; Oxidation-Reduction; Pentanones; Staphylococcus aureus; Substrate Specificity	1988
Kinetics of alpha-dicarbonyls reduction by L-glycol dehydrogenase from hen muscle. Archives of biochemistry and biophysics, 1983, Jul-01, Volume: 224, Issue:1 Topics: Alcohol Oxidoreductases; Animals; Chemical Phenomena; Chemistry; Chickens; Diacetyl; Female; Ketones; Kinetics; Muscles; NADP; Oxidation-Reduction; Pentanones; Pyruvaldehyde; Substrate Specificity	1983
Modification of essential arginine residues of pigeon liver malic enzyme. Biochimica et biophysica acta, 1981, Aug-13, Volume: 660, Issue:2 Topics: Animals; Arginine; Columbidae; Diacetyl; Kinetics; Liver; Malate Dehydrogenase; NADP; Pentanones; Phenylglyoxal; Protein Binding; Pyruvaldehyde	1981
Roles of arginyl residues in pyridoxamine-5'-phosphate oxidase from rabbit liver. Biochemistry, 1981, Sep-29, Volume: 20, Issue:20 Topics: Amino Acids; Animals; Arginine; Diacetyl; Liver; Oxidoreductases Acting on CH-NH Group Donors; Pentanones; Phenylglyoxal; Pyridoxaminephosphate Oxidase; Rabbits	1981
Origin of 2,3-pentanedione and 2,3-butanedione in D-glucose/L-alanine Maillard model systems. Journal of agricultural and food chemistry, 1999, Volume: 47, Issue:8 Topics: Alanine; Carbon Isotopes; Diacetyl; Gas Chromatography-Mass Spectrometry; Glucose; Maillard Reaction; Models, Chemical; Pentanones	1999
Vicinal diketone formation in yogurt: (13)C precursors and effect of branched-chain amino acids. Journal of agricultural and food chemistry, 2000, Volume: 48, Issue:3 Topics: Amino Acids, Branched-Chain; Carbon Isotopes; Diacetyl; Fermentation; Gas Chromatography-Mass Spectrometry; Humans; Lactobacillus; Odorants; Pentanones; Streptococcus; Yogurt	2000
The EGL-4 PKG acts with KIN-29 salt-inducible kinase and protein kinase A to regulate chemoreceptor gene expression and sensory behaviors in Caenorhabditis elegans. Genetics, 2008, Volume: 180, Issue:3 Topics: Animals; Animals, Genetically Modified; Behavior, Animal; Body Size; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Chemoreceptor Cells; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP-Dependent Protein Kinases; Diacetyl; Gene Expression Regulation; Histone Deacetylases; Mutation; Pentanones; Phosphorylation; Protein Serine-Threonine Kinases; Sensory Receptor Cells; Transcription Factors	2008
Respiratory and olfactory cytotoxicity of inhaled 2,3-pentanedione in Sprague-Dawley rats. The American journal of pathology, 2012, Volume: 181, Issue:3 Topics: Administration, Inhalation; Animals; Cadherins; Caspase 3; Cell Death; Diacetyl; Epithelium; Fluorescent Antibody Technique; Gene Expression Regulation; Male; Neurons; Olfactory Bulb; Olfactory Marker Protein; Pentanones; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Respiratory System; RNA, Messenger; Staining and Labeling; Sugar Alcohol Dehydrogenases; Time Factors	2012
Construction of self-cloning bottom-fermenting yeast with low vicinal diketone production by the homo-integration of ILV5. Yeast (Chichester, England), 2012, Volume: 29, Issue:10 Topics: Alcohol Oxidoreductases; Beer; Cloning, Molecular; Diacetyl; Fermentation; Hydroxybutyrates; Lactates; Mitochondrial Proteins; Organisms, Genetically Modified; Pentanones; Saccharomyces cerevisiae; Time Factors; Transformation, Genetic	2012
Still searching for better butter flavoring. Environmental health perspectives, 2012, Volume: 120, Issue:12 Topics: Animals; Bronchiolitis Obliterans; Butter; Diacetyl; Flavoring Agents; Humans; Inhalation Exposure; Occupational Diseases; Occupational Exposure; Pentanones	2012
Influence of valine and other amino acids on total diacetyl and 2,3-pentanedione levels during fermentation of brewer's wort. Applied microbiology and biotechnology, 2013, Volume: 97, Issue:15 Topics: Amino Acids; Diacetyl; Fermentation; Pentanones; Saccharomyces; Valine	2013
Popcorn flavoring effects on reactivity of rat airways in vivo and in vitro. Journal of toxicology and environmental health. Part A, 2013, Volume: 76, Issue:11 Topics: Acetic Acid; Acetoin; Airway Resistance; Animals; Bronchial Hyperreactivity; Bronchial Provocation Tests; Cells, Cultured; Complex Mixtures; Diacetyl; Flavoring Agents; Food; Inhalation Exposure; Male; Methacholine Chloride; Muscle, Smooth; Pentanones; Rats; Rats, Sprague-Dawley; Trachea	2013
Evaluation of the hypersensitivity potential of alternative butter flavorings. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2013, Volume: 62 Topics: Animals; Butter; Dermatitis, Allergic Contact; Diacetyl; Dose-Response Relationship, Immunologic; Female; Flavoring Agents; Hexanones; Hypersensitivity; Immunoglobulin E; Irritants; Lymph Nodes; Lymphocytes; Mice, Inbred BALB C; Occupational Exposure; Pentanones	2013
Evaluation of electronic cigarette liquids and aerosol for the presence of selected inhalation toxins. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2015, Volume: 17, Issue:2 Topics: Administration, Inhalation; Aerosols; Diacetyl; Electronic Nicotine Delivery Systems; Female; Flavoring Agents; Humans; Nicotine; Pentanones; Smoking	2015
Evaluation of four α-diketones for toll-like receptor-4 (TLR-4) activation in a human transfected cell line. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2014, Volume: 74 Topics: Diacetyl; Dose-Response Relationship, Drug; HEK293 Cells; Hexanones; Humans; Ketones; Pentanones; Toll-Like Receptor 4; Up-Regulation	2014
Optimal design of experiments applied to headspace solid phase microextraction for the quantification of vicinal diketones in beer through gas chromatography-mass spectrometric detection. Analytica chimica acta, 2015, Aug-05, Volume: 887 Topics: Beer; Diacetyl; Equipment Design; Gas Chromatography-Mass Spectrometry; Limit of Detection; Pentanones; Reproducibility of Results; Solid Phase Microextraction	2015
Diacetyl and 2,3-pentanedione exposure of human cultured airway epithelial cells: Ion transport effects and metabolism of butter flavoring agents. Toxicology and applied pharmacology, 2015, Dec-15, Volume: 289, Issue:3 Topics: Bronchi; Butter; Cells, Cultured; Diacetyl; Epithelial Cells; Flavoring Agents; Humans; Inhalation Exposure; Ion Transport; Methacholine Chloride; Microwaves; Occupational Exposure; Pentanones	2015
Respiratory morbidity in a coffee processing workplace with sentinel obliterative bronchiolitis cases. American journal of industrial medicine, 2015, Volume: 58, Issue:12 Topics: Adult; Airway Obstruction; Bronchiolitis Obliterans; Coffee; Cross-Sectional Studies; Diacetyl; Dyspnea; Female; Flavoring Agents; Food-Processing Industry; Forced Expiratory Volume; Humans; Lung; Male; Occupational Diseases; Occupational Exposure; Pentanones; Respiration; Spirometry; Vital Capacity; Workplace	2015
Flavoring Chemicals in E-Cigarettes: Diacetyl, 2,3-Pentanedione, and Acetoin in a Sample of 51 Products, Including Fruit-, Candy-, and Cocktail-Flavored E-Cigarettes. Environmental health perspectives, 2016, Volume: 124, Issue:6 Topics: Acetoin; Diacetyl; Electronic Nicotine Delivery Systems; Flavoring Agents; Humans; Inhalation Exposure; Pentanones	2016
Chemical Reactivity and Respiratory Toxicity of the α-Diketone Flavoring Agents: 2,3-Butanedione, 2,3-Pentanedione, and 2,3-Hexanedione. Toxicologic pathology, 2016, Volume: 44, Issue:5 Topics: Animals; Diacetyl; Dose-Response Relationship, Drug; Flavoring Agents; Hexanones; Inhalation Exposure; Lung; Male; Pentanones; Rats	2016
Environmental characterization of a coffee processing workplace with obliterative bronchiolitis in former workers. Journal of occupational and environmental hygiene, 2016, 10-02, Volume: 13, Issue:10 Topics: Air Pollutants, Occupational; Bronchiolitis Obliterans; Coffee; Diacetyl; Dust; Flavoring Agents; Food-Processing Industry; Humans; Occupational Exposure; Pentanones	2016
Response to "Comment on 'Flavoring Chemicals in E-Cigarettes: Diacetyl, 2,3-Pentanedione, and Acetoin in a Sample of 51 Products, Including Fruit-, Candy-, and Cocktail-Flavored E-Cigarettes'". Environmental health perspectives, 2016, 06-01, Volume: 124, Issue:6 Topics: Acetoin; Candy; Diacetyl; Electronic Nicotine Delivery Systems; Flavoring Agents; Fruit; Pentanones	2016
Comment on "Flavoring Chemicals in E-Cigarettes: Diacetyl, 2,3-Pentanedione, and Acetoin in a Sample of 51 Products, Including Fruit-, Candy-, and Cocktail-Flavored E-Cigarettes". Environmental health perspectives, 2016, 06-01, Volume: 124, Issue:6 Topics: Acetoin; Candy; Diacetyl; Electronic Nicotine Delivery Systems; Flavoring Agents; Fruit; Pentanones	2016
α,β-Dicarbonyl reduction is mediated by the Saccharomyces Old Yellow Enzyme. FEMS yeast research, 2016, Volume: 16, Issue:5 Topics: Acetoin; Diacetyl; Gene Expression Profiling; Kinetics; Mass Spectrometry; NADP; NADPH Dehydrogenase; Oxidation-Reduction; Pentanones; Saccharomyces cerevisiae	2016
Increased sensitivity of OSHA method analysis of diacetyl and 2,3-pentanedione in air. Journal of occupational and environmental hygiene, 2017, Volume: 14, Issue:5 Topics: Diacetyl; Environmental Monitoring; Gas Chromatography-Mass Spectrometry; National Institute for Occupational Safety and Health, U.S.; Occupational Exposure; Pentanones; United States; United States Occupational Safety and Health Administration	2017
Pathology of diacetyl and 2,3-pentanedione airway lesions in a rat model of obliterative bronchiolitis. Toxicology, 2017, 08-01, Volume: 388 Topics: Animals; Basement Membrane; Bronchiolitis Obliterans; Diacetyl; Disease Models, Animal; Flavoring Agents; Humans; Inhalation Exposure; Male; Occupational Exposure; Pentanones; Rats; Rats, Wistar; Respiratory Mucosa; Species Specificity	2017
NIOSH Proposes RELs for Diacetyl and 2,3-Pentanedione: The agency recommends a recommended exposure limit of 5 ppb for diacetyl as a time-weighted average for up to 8 hours/day during a 40-hour work week and a short-term exposure limit of 25 parts per bil Occupational health & safety (Waco, Tex.), 2017, Volume: 86, Issue:2 Topics: Air Pollutants, Occupational; Diacetyl; Humans; National Institute for Occupational Safety and Health, U.S.; Occupational Exposure; Pentanones; Threshold Limit Values; Time Factors; United States	2017
Potential Hazards Not Communicated in Safety Data Sheets of Flavoring Formulations, Including Diacetyl and 2,3-Pentanedione. Annals of work exposures and health, 2019, 01-07, Volume: 63, Issue:1 Topics: Diacetyl; Environmental Monitoring; Flavoring Agents; Humans; Inhalation Exposure; Occupational Exposure; Pentanones; Volatile Organic Compounds	2019
Measurement of Diacetyl and 2,3-Pentanedione in the Coffee Industry Using Thermal Desorption Tubes and Gas Chromatography-Mass Spectrometry. Annals of work exposures and health, 2019, 04-19, Volume: 63, Issue:4 Topics: Air Pollutants, Occupational; Coffee; Diacetyl; Flavoring Agents; Food Industry; Gas Chromatography-Mass Spectrometry; Humans; Occupational Exposure; Pentanones; Volatile Organic Compounds	2019
A New Method for Workplace Monitoring of Airborne Diacetyl and 2,3-Pentanedione Using Thermal Desorption Tubes and Gas Chromatography-Mass Spectrometry. Annals of work exposures and health, 2019, 04-19, Volume: 63, Issue:4 Topics: Air Pollutants, Occupational; Diacetyl; Environmental Monitoring; Gas Chromatography-Mass Spectrometry; Humans; Occupational Exposure; Pentanones; Volatile Organic Compounds; Workplace	2019
Acetoin is a precursor to diacetyl in e-cigarette liquids. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2019, Volume: 133 Topics: Acetoin; Diacetyl; Drug Stability; Electronic Nicotine Delivery Systems; Flavoring Agents; Glycerol; Hydrogen-Ion Concentration; Nicotine; Oxidation-Reduction; Pentanones; Propylene Glycol	2019
Multi-target optimization of solid phase microextraction to analyse key flavour compounds in wort and beer. Food chemistry, 2020, Jul-01, Volume: 317 Topics: Beer; Diacetyl; Food Analysis; Gas Chromatography-Mass Spectrometry; Ketones; Pentanones; Reproducibility of Results; Solid Phase Microextraction; Taste; Volatile Organic Compounds	2020
Exposures and Emissions in Coffee Roasting Facilities and Cafés: Diacetyl, 2,3-Pentanedione, and Other Volatile Organic Compounds. Frontiers in public health, 2020, Volume: 8 Topics: Coffee; Diacetyl; Humans; Occupational Exposure; Pentanones; United States; Volatile Organic Compounds	2020
Model Predictions of Occupational Exposures to Diacetyl and 2,3-Pentanedione Emitted From Roasted Whole Bean and Ground Coffee: Influence of Roast Level and Physical Form on Specific Emission Rates. Frontiers in public health, 2022, Volume: 10 Topics: Coffee; Diacetyl; Humans; Occupational Exposure; Pentanones	2022
Case Study: Efficacy of Engineering Controls in Mitigating Diacetyl and 2,3-Pentanedione Emissions During Coffee Grinding. Frontiers in public health, 2022, Volume: 10 Topics: Animals; Bronchiolitis; Coffee; Diacetyl; Flavoring Agents; Occupational Exposure; Pentanones; Rats	2022
Impacts of risk assessment data, assumptions, and methods: Considering the evidence for diacetyl and 2,3-pentanedione. Frontiers in public health, 2022, Volume: 10 Topics: Animals; Coffee; Diacetyl; Humans; Ketones; Pentanones; Risk Assessment	2022
Toxicity studies of acetoin and 2,3-pentanedione administered by inhalation to Wistar Han [Crl:WI(Han)] rats and B6C3F1/N mice. Toxicity report series, 2023, Issue:98 Topics: Acetoin; Animals; Diacetyl; Ketones; Mice; Mice, Inbred Strains; Rats; Rats, Wistar	2023