2,3-dimethoxy-1,4-naphthoquinone has been researched along with naphthoquinones in 92 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 28 (30.43) | 18.2507 |
| 2000's | 47 (51.09) | 29.6817 |
| 2010's | 16 (17.39) | 24.3611 |
| 2020's | 1 (1.09) | 2.80 |
| Authors | Studies |
|---|---|
| Carpenedo, F; Floreani, M | 2 |
| Dypbukt, JM; Manzo, L; Nicotera, P; Orrenius, S; Rossi, AD | 1 |
| Cohen, GM; Hartley, JA; Morgan, WA | 1 |
| Adam, A; Cohen, GM; Hardwick, SJ; Smith, LL | 1 |
| Dypbukt, JM; Nicotera, P; Thor, H | 1 |
| Morgan, WA | 3 |
| Baker, LH; Corbett, TH; Djuric, Z; Heilbrun, LK; Valeriote, FA | 1 |
| Berger, G; Boullais, C; Breton, J; Burie, JR; Nabedryk, E | 1 |
| Forman, HJ; Iwamoto, T; Kugelman, A; Shi, MM; Tian, L | 1 |
| Forman, HJ; Iwamoto, T; Shi, MM | 1 |
| Ankarcrona, M; Burkitt, M; Dypbukt, JM; Nicotera, P; Orrenius, S; Sjöholm, A; Ström, K | 1 |
| Choy, HA; Forman, HJ; Gozal, E; Shi, M | 1 |
| Chan, TM; Chen, Y | 1 |
| Chipman, JK; Coleman, R; Stone, V | 1 |
| Henry, TR; Wallace, KB | 1 |
| Forman, HJ; Shi, MM; Tian, L | 1 |
| Brüne, B; Pfeilschifter, J; Sandau, K | 2 |
| Forman, HJ; Giulivi, C; Liu, RM; Shi, MM | 1 |
| Chung, JH; Lee, JY; Lee, MY; Park, JS; Seung, SA | 1 |
| Buyon, JP; Casiano, CA; Chan, EK; Di Donato, F; Miranda, ME; Ochs, RL; Rashbaum, W; Tseng, CE | 1 |
| Karczewski, JM; Noordhoek, J; Peters, JG | 2 |
| Darley-Usmar, VM; Jo, H; McAndrew, J; Moellering, D | 1 |
| Brüne, B; Callsen, D; von Knethen, A | 1 |
| Ahn, BZ; Cho, H; Kim, Y; Song, GY; You, YJ | 1 |
| Klatt, P; Lamas, S; López-Muñoz, MJ; Michel, T; Navarro-Antolín, J; Soria, J | 1 |
| Böddinghaus, B; Brade, V; Briner, VA; Dorsch, S; Franzen, R; Huwiler, A; Pautz, A; Pfeilschifter, J | 1 |
| Bae, ON; Chung, JH; Chung, SM; Kim, SR; Lee, JY; Lee, MY | 1 |
| Giulivi, C; Sugawara, M; Sugawara, Y; Wen, K | 1 |
| Böddinghaus, B; Briner, VA; Dorsch, S; Franzen, R; Huwiler, A; Pautz, A; Pfeilschifter, J | 1 |
| Gao, F; Li, H; Shi, G; Shi, X; Tang, X; Wang, Z; Yi, J | 2 |
| Duncan, RF; Hagedorn, CH; Peterson, H; Sevanian, A | 1 |
| Dickinson, DA; Forman, HJ; Iles, KE; Krzywanski, DM; Venglarik, CJ; Watanabe, N; Zhang, H | 1 |
| Bolaños, JP; Eleno, N; García-Criado, J; López-Novoa, JM; Martínez-Salgado, C; Rodríguez-Barbero, A; Tavares, P | 1 |
| Forman, HJ; Watanabe, N | 1 |
| Denny, JS; Hammermeister, DE; Kolanczyk, RC; Schmieder, PK; Sheedy, BR; Tapper, MA | 1 |
| Cross, JV; Nguyen, SM; Seanor, KL; Templeton, DJ; Yan, M | 1 |
| Bauer, H; Bauer, HC; Bresgen, N; Eckl, PM; Karlhuber, G; Krizbai, I | 1 |
| Abdelmohsen, K; Gerber, PA; Klotz, LO; Sies, H; von Montfort, C | 1 |
| Kim, SH; Lee, IJ; Park, EM; Park, YM; Song, GY | 1 |
| Dickinson, DA; Forman, HJ; Franklin, CC; Iles, KE; Kavanagh, TJ; Krzywanski, DM; Liu, RM; Wigley, AF | 1 |
| Dickinson, DA; Forman, HJ; Liu, RM; Watanabe, N | 1 |
| Gao, F; Shi, GY; Tang, XM; Yi, J; Yuan, JQ | 1 |
| Flögel, U; Gödecke, A; Klotz, LO; Schrader, J | 1 |
| Ceccatelli, S; Emgård, M; Enoksson, M; Orrenius, S; Robertson, JD; Sleeper, E; Tamm, C | 1 |
| Bauer, H; Bauer, HC; Bresgen, N; Eckl, PM; Farkas, A; Krizbai, IA; Szatmári, E; Traweger, A; Wejksza, K | 1 |
| Hofer, HW; Kienhöfer, J; Namgaladze, D; Shcherbyna, I; Ullrich, V | 1 |
| Brüne, B; Callapina, M; Köhl, R; Schmid, T; Zhou, J | 1 |
| Graf, J; Gross, R; Haas, AH; Lancaster, CR; Madej, MG; Mäntele, W; Sauer, US; Schwalbe, H; Simon, J | 1 |
| Alija, AJ; Bresgen, N; Eckl, PM; Langhans, CD; Siems, W; Sommerburg, O | 1 |
| Ishihara, Y; Shiba, D; Shimamoto, N | 1 |
| Coleman, R; Elias, E; Milkiewicz, P; Pérez, LM; Roma, MG; Sánchez Pozzi, EJ | 1 |
| Davis, LS; Ismail, AS; Karp, DR; King, MR | 1 |
| Cho, H; Chung, Y; Jung, JK; Kim, BH; Park, SH; Yoo, J | 1 |
| Brüne, B; Köhl, R; Zhou, J | 1 |
| Bauer, HC; Bresgen, N; Eckl, P; Jaksch, H; Krizbai, I; Tempfer, H | 1 |
| Kawata, K; Okabe, S; Shimazaki, R; Yokoo, H | 1 |
| Buzás, K; Deli, MA; Farkas, AE; Hunyadi-Gulyás, E; Hutamekalin, P; Krizbai, IA; Medzihradszky, KF; Meksuriyen, D; Nagyoszi, P; Orbók, A; Veszelka, S; Wilhelm, I | 1 |
| Giardina, TM; Joyce, DA; Lo, SZ; Steer, JH | 1 |
| Ceccatelli, S; Tamm, C; Zhivotovsky, B | 1 |
| Garcia-Rojas, R; Jackson, RM | 1 |
| Madamanchi, NR; Niu, XL; Runge, MS; Tchivilev, I; Vendrov, AE | 1 |
| Bresgen, N; Eckl, PM; Horvathova, E; Slamenova, D | 1 |
| Deb, S; Johnson, EE; Robalinho-Teixeira, RL; Wessling-Resnick, M | 1 |
| Athersuch, TJ; Chan, PH; Charlwood, JK; Gant, TW; Keun, HC; Luo, J; Lutz, U; Lutz, WK; Lyon, JJ; Parry, JD; Phillips, KM; Pointon, AV; Singh, R; Taylor, EL; Teichert, F; Vetillard, A | 1 |
| Berridge, MV; Tan, AS | 1 |
| Saltikov, CW; Zargar, K | 1 |
| Aboua, YG; Brooks, N; du Plessis, SS; Reichgelt, P | 1 |
| Clanton, TL; Reiser, PJ; Wright, VP | 1 |
| Deng, S; Forstermann, U; Li, H; Spanier, G; Tobias, S; Wojnowski, L; Xia, N; Xu, H | 1 |
| Ishihara, Y; Ishii, S; Onishi, Y; Sakai, Y; Shimamoto, N; Yamamura, N | 1 |
| Bose, R; Cascante, A; Ceccatelli, S; Hermanson, O; Moors, M; Tofighi, R | 1 |
| Mutsaers, HA; Tofighi, R | 1 |
| Horváthová, E; Hunáková, L; Klusová, V; Kozics, K; Kusznierewicz, B; Mučaji, P; Slameňová, D; Srančíková, A | 1 |
| Broniowska, KA; Diers, AR; Hogg, N | 1 |
| Araki, M; Dong, Y; Fukushima, N; Hirane, M; Honoki, K; Tsujiuchi, T | 1 |
| Frye, RE; James, SJ; Melnyk, S; Pavliv, O; Rose, S; Slattery, J; Tippett, M; Wynne, R | 1 |
| Choi, EJ; Hong, MP; Kie, JH; Kim, HR; Lee, A; Lee, HK; Lim, W; Moon, BI; Seoh, JY | 1 |
| Appukuttan, A; Hahn, S; Kumar, S; Ladilov, Y; Maghnouj, A; Peter Reusch, H | 1 |
| Berthiaume, Y; Bouvet, GF; Dagenais, A; Legendre, P; Massé, C; Voisin, G | 1 |
| Aftab, O; Fryknäs, M; Gustafsson, MG; Hammerling, U; Larsson, R; Nazir, M | 1 |
| Alli, AA; Bao, Q; Eaton, DC; Liu, BC; Lu, XY; Ma, HP; Thai, TL; Wang, LH; Wang, WZ; Yang, LL; Zhai, YJ | 1 |
| Chacko, B; Darley-Usmar, V; Heath, SL; Kramer, PA; Overton, ET; Prichard, L; Ravi, S | 1 |
| Chacko, BK; Darley-Usmar, VM; Mitchell, T; Zhi, D | 1 |
| Wu, Y; Yang, P; Yu, J | 1 |
| Hwang, SK; Jun, DY; Kim, KY; Kim, MJ; Kim, YH; Park, SY | 1 |
| Brancolini, C; Cefalù, S; Ciotti, S; Comelli, M; Di Giorgio, E; Iuliano, L; Mavelli, I | 1 |
1 review(s) available for 2,3-dimethoxy-1,4-naphthoquinone and naphthoquinones
| Article | Year |
|---|---|
Quinones and glutathione metabolism.
Topics: Animals; Cytochrome-B(5) Reductase; Dicumarol; Enzyme Inhibitors; gamma-Glutamyltransferase; Gene Expression Regulation, Enzymologic; Glutamate-Cysteine Ligase; Glutathione; Glutathione Peroxidase; Humans; Hydrogen Peroxide; Molecular Structure; NAD(P)H Dehydrogenase (Quinone); NADPH-Ferrihemoprotein Reductase; Naphthoquinones; Nitric Oxide Synthase; Oxidation-Reduction; Protein Isoforms; Quinone Reductases; Quinones; Response Elements; Trans-Activators; Transcription, Genetic; Tumor Cells, Cultured; Vitamin K 3; Xenobiotics | 2004 |
91 other study(ies) available for 2,3-dimethoxy-1,4-naphthoquinone and naphthoquinones
| Article | Year |
|---|---|
The catecholamine-mediated positive inotropic effect of simple quinones is related to superoxide anion generation.
Topics: Animals; Atrial Function; Benzoquinones; Catecholamines; Cyclohexenes; Free Radicals; Guinea Pigs; Heart Atria; In Vitro Techniques; Lipid Peroxidation; Microsomes; Mitochondria, Heart; Myocardial Contraction; Naphthoquinones; Oxidation-Reduction; Rats; Superoxides; Vitamin K | 1992 |
Thiol modification and cell signalling in chemical toxicity.
Topics: Animals; Calcium; Cell Death; Cell Division; Cell Line; Cell Survival; Humans; Mercuric Chloride; Naphthoquinones; Oxidants; PC12 Cells; Protein Kinase C; Signal Transduction; Sulfhydryl Compounds | 1992 |
Quinone-induced DNA single strand breaks in rat hepatocytes and human chronic myelogenous leukaemic K562 cells.
Topics: Animals; Cell Division; DNA Damage; DNA, Single-Stranded; Dose-Response Relationship, Drug; Humans; Liver; NAD; Naphthoquinones; Phenanthrolines; Rats; Trypan Blue; Tumor Cells, Cultured; Vitamin K | 1992 |
Modifications of cardiac contractility by redox cycling alkylating and mixed redox cycling/alkylating quinones.
Topics: Alkylating Agents; Animals; Atrial Function, Left; Benzoquinones; Guinea Pigs; Heart; Heart Atria; Mice; Microsomes; Mitochondria, Heart; Myocardial Contraction; NADH, NADPH Oxidoreductases; Naphthoquinones; Oxidation-Reduction; Quinones; Substrate Cycling; Superoxides; Vitamin K | 1991 |
Potentiation of the cell specific toxicity of paraquat by 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU). Implications for the heterogeneous distribution of glutathione (GSH) in rat lung.
Topics: Adenosine Triphosphate; Animals; Carmustine; Drug Synergism; Glutathione; Glutathione Reductase; Kinetics; Lung; Lung Diseases; Male; Naphthoquinones; Oxidation-Reduction; Paraquat; Putrescine; Rats; Rats, Inbred Strains; Serotonin; Spermidine | 1990 |
Intracellular Ca2+ chelators prevent DNA damage and protect hepatoma 1C1C7 cells from quinone-induced cell killing.
Topics: Animals; Calcium; Cell Survival; Chelating Agents; Cytosol; DNA Damage; Glutathione; Liver Neoplasms, Experimental; Mice; Naphthoquinones; Oxidation-Reduction; Quinones; Tumor Cells, Cultured | 1990 |
Naphthoquinone-induced DNA damage in the absence of oxidative stress.
Topics: Cell Line; DNA Damage; DNA, Neoplasm; Humans; Leukemia, Erythroblastic, Acute; NAD; Naphthoquinones; Oxidation-Reduction; Oxidative Stress; Tumor Cells, Cultured; Vitamin K | 1995 |
Detoxification ability and toxicity of quinones in mouse and human tumor cell lines used for anticancer drug screening.
Topics: Animals; Antineoplastic Agents; Drug Screening Assays, Antitumor; Glutathione Transferase; Humans; Mice; NAD(P)H Dehydrogenase (Quinone); Naphthoquinones; Quinones; Superoxide Dismutase; Tumor Cells, Cultured; Vitamin K | 1995 |
Pyridine nucleotide hydrolysis and interconversion in rat hepatocytes during oxidative stress.
Topics: Animals; Cells, Cultured; Enzyme Activation; Liver; Male; NAD; Naphthoquinones; Niacinamide; Oxidative Stress; Peroxides; Poly(ADP-ribose) Polymerase Inhibitors; Rats; Rats, Wistar; tert-Butylhydroperoxide | 1995 |
Binding sites of quinones in photosynthetic bacterial reaction centers investigated by light-induced FTIR difference spectroscopy: binding of chainless symmetrical quinones to the QA site of Rhodobacter sphaeroides.
Topics: Binding Sites; Hydrogen Bonding; Naphthoquinones; Photosynthetic Reaction Center Complex Proteins; Quinones; Rhodobacter sphaeroides; Spectrophotometry; Spectrophotometry, Infrared; Spectroscopy, Fourier Transform Infrared; Vitamin K 1 | 1994 |
Quinone-induced oxidative stress elevates glutathione and induces gamma-glutamylcysteine synthetase activity in rat lung epithelial L2 cells.
Topics: Animals; Base Sequence; Cells, Cultured; Cycloheximide; Dactinomycin; Epithelium; Glutamate-Cysteine Ligase; Glutathione; Lung; Molecular Sequence Data; Naphthoquinones; Oxidative Stress; Rats; RNA, Messenger; Transcription, Genetic | 1994 |
gamma-Glutamylcysteine synthetase and GSH increase in quinone-induced oxidative stress in BPAEC.
Topics: Animals; Base Sequence; Benzoquinones; Cattle; Cells, Cultured; Cycloheximide; Dactinomycin; Endothelium, Vascular; Glutamate-Cysteine Ligase; Glutathione; Molecular Probes; Molecular Sequence Data; Naphthoquinones; Oxidative Stress; Pulmonary Artery; RNA, Messenger | 1994 |
Different prooxidant levels stimulate growth, trigger apoptosis, or produce necrosis of insulin-secreting RINm5F cells. The role of intracellular polyamines.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Adenosylmethionine Decarboxylase; Animals; Apoptosis; Cell Division; Cell Line; Cell Survival; Deoxyguanosine; Dose-Response Relationship, Drug; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Naphthoquinones; Necrosis; Oxidants; Polyamines; Tetradecanoylphorbol Acetate; Time Factors | 1994 |
Extracellular glutathione and gamma-glutamyl transpeptidase prevent H2O2-induced injury by 2,3-dimethoxy-1,4-naphthoquinone.
Topics: 3T3 Cells; Animals; Blotting, Western; gamma-Glutamyltransferase; Gene Expression; Glutathione; Glycosylation; Humans; Hydrogen Peroxide; Isoxazoles; Mice; Naphthoquinones; Transfection | 1993 |
Orthovanadate and 2,3-dimethoxy-1,4-naphthoquinone augment growth factor-induced cell proliferation and c-fos gene expression in 3T3-L1 cells.
Topics: 3T3 Cells; Animals; Cell Division; DNA; Electron Spin Resonance Spectroscopy; Epidermal Growth Factor; Gene Expression; Genes, fos; Growth Substances; Insulin; Mice; Naphthoquinones; Oxidation-Reduction; Phosphatidylinositol 3-Kinases; Phosphotransferases; Platelet-Derived Growth Factor; Receptor, Insulin; S Phase; Vanadates | 1993 |
DNA single-strand breakage in mammalian cells induced by redox cycling quinones in the absence of oxidative stress.
Topics: Adenosine Triphosphate; Cell Death; Cell Division; DNA Damage; DNA, Neoplasm; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; NAD; Naphthoquinones; Oxidation-Reduction; Oxidative Stress; Substrate Cycling; Tumor Cells, Cultured; Vitamin K | 1995 |
Comparison of the effects of redox cycling and arylating quinones on hepatobiliary function and glutathione homeostasis in rat hepatocyte couplets.
Topics: Adenosine Triphosphate; Animals; Benzoquinones; Biliary Tract; Cell Membrane; Cell Separation; Glutathione; Homeostasis; Liver; Naphthoquinones; Oxidation-Reduction; Rats; Vacuoles; Vitamin K | 1996 |
Differential mechanisms of cell killing by redox cycling and arylating quinones.
Topics: Animals; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Liver; Male; Membrane Potentials; Mitochondria, Liver; Naphthoquinones; Rats; Rats, Sprague-Dawley; Vitamin K 3 | 1996 |
Increased transcription of the regulatory subunit of gamma-glutamylcysteine synthetase in rat lung epithelial L2 cells exposed to oxidative stress or glutathione depletion.
Topics: Animals; Buthionine Sulfoximine; Cell Line; Epithelium; Glutamate-Cysteine Ligase; Glutathione; Lung; Naphthoquinones; Oxidative Stress; Rats; RNA, Messenger; Transcription, Genetic; Up-Regulation | 1997 |
Nitric oxide and superoxide induced p53 and Bax accumulation during mesangial cell apoptosis.
Topics: Animals; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Biotin; Cells, Cultured; Chromosomes; Cytokines; Deoxyuracil Nucleotides; DNA Fragmentation; Glomerular Mesangium; Glutathione; Naphthoquinones; Nitric Oxide; Nitroso Compounds; Oxygen; Platelet Aggregation Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Pyrrolidines; Rats; S-Nitrosoglutathione; Staining and Labeling; Superoxide Dismutase; Superoxides; Thiocarbamates; Time Factors; Tumor Suppressor Protein p53; Up-Regulation | 1997 |
Quinones increase gamma-glutamyl transpeptidase expression by multiple mechanisms in rat lung epithelial cells.
Topics: Animals; Antioxidants; Cells, Cultured; Epithelial Cells; gamma-Glutamyltransferase; Hydrogen Peroxide; Hydroquinones; Lung; Naphthoquinones; Oxidation-Reduction; Rats; Reactive Oxygen Species; Superoxides | 1998 |
Nitrosative and oxidative stress induced heme oxygenase-1 accumulation in rat mesangial cells.
Topics: Animals; Apoptosis; Cells, Cultured; DNA Fragmentation; Enzyme Induction; Glomerular Mesangium; Glutathione; Heme Oxygenase (Decyclizing); Naphthoquinones; Neuroprotective Agents; Nitric Oxide; Nitroso Compounds; Oxidative Stress; Rats; S-Nitrosoglutathione; Tumor Suppressor Protein p53; Up-Regulation | 1998 |
The relative importance of oxidative stress versus arylation in the mechanism of quinone-induced cytotoxicity to platelets.
Topics: Alkylation; Animals; Benzoquinones; Blood Platelets; Cell Survival; Chromatography, High Pressure Liquid; Female; Glutathione; Homeostasis; L-Lactate Dehydrogenase; Naphthoquinones; Oxidative Stress; Oxygen Consumption; Quinones; Rats; Rats, Sprague-Dawley; Vitamin K | 1998 |
Accessibility of SSA/Ro and SSB/La antigens to maternal autoantibodies in apoptotic human fetal cardiac myocytes.
Topics: Antigen-Antibody Reactions; Antigens, Surface; Aorta; Apoptosis; Autoantibodies; Autoantigens; Autoimmune Diseases; Biological Transport; Cell Nucleus; Cell Separation; Cells, Cultured; Collagenases; Enzyme Inhibitors; Female; Fetal Heart; Fetal Proteins; Heart Block; Humans; Immunity, Maternally-Acquired; Muscle Proteins; Myocardium; Naphthoquinones; Pregnancy; Pregnancy Complications; Protein Isoforms; Ribonucleoproteins; RNA, Small Cytoplasmic; SS-B Antigen; Staurosporine | 1998 |
Prevention of oxidant-induced cell death in Caco-2 colon carcinoma cells after inhibition of poly(ADP-ribose) polymerase and Ca2+ chelation: involvement of a common mechanism.
Topics: Adenosine Triphosphate; Benzamides; Caco-2 Cells; Calcium; Cell Death; Chelating Agents; DNA Damage; DNA, Neoplasm; Egtazic Acid; Glutathione; Humans; Hydrogen Peroxide; Kinetics; NAD; Naphthoquinones; Oxidants; Oxidative Stress; Poly(ADP-ribose) Polymerase Inhibitors; Vitamin K | 1999 |
Quinone toxicity in DT-diaphorase-efficient and -deficient colon carcinoma cell lines.
Topics: Adenosine Triphosphate; Cell Survival; Colonic Neoplasms; Dicumarol; Glutathione; Glutathione Disulfide; Humans; Kinetics; NAD(P)H Dehydrogenase (Quinone); Naphthoquinones; Neoplasm Proteins; Sulfhydryl Compounds; Tumor Cells, Cultured; Vitamin K | 1999 |
Effects of pyrrolidine dithiocarbamate on endothelial cells: protection against oxidative stress.
Topics: Animals; Antioxidants; Apoptosis; Cattle; DNA; Endothelium, Vascular; Glutathione; Glutathione Disulfide; In Vitro Techniques; Naphthoquinones; NF-kappa B; Oxidation-Reduction; Oxidative Stress; Pyrrolidines; Superoxides; Thiocarbamates | 1999 |
Superoxide attenuates macrophage apoptosis by NF-kappa B and AP-1 activation that promotes cyclooxygenase-2 expression.
Topics: Adjuvants, Immunologic; Animals; Apoptosis; Cell Line; Cyclooxygenase 2; Dose-Response Relationship, Drug; Isoenzymes; Macrophages; Mice; Naphthoquinones; NF-kappa B; Nitric Oxide; Prostaglandin-Endoperoxide Synthases; Superoxides; Transcription Factor AP-1; Tumor Suppressor Protein p53 | 1999 |
Naphthazarin derivatives (VII): antitumor action against ICR mice bearing ascitic S-180 cells.
Topics: Animals; Antineoplastic Agents; Drug Screening Assays, Antitumor; Male; Mice; Mice, Inbred ICR; Naphthoquinones; Sarcoma 180; Tumor Cells, Cultured | 2001 |
Formation of peroxynitrite in vascular endothelial cells exposed to cyclosporine A.
Topics: Animals; Aorta; Cattle; Cells, Cultured; Cyclic N-Oxides; Cyclosporine; Endothelium, Vascular; Enzyme Inhibitors; Flow Cytometry; Fluorescent Dyes; Free Radical Scavengers; Humans; Immunosuppressive Agents; Models, Biological; Naphthoquinones; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Oxidants; Spin Trapping; Superoxide Dismutase; Superoxides | 2001 |
Superoxide potently induces ceramide formation in glomerular endothelial cells.
Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Cattle; Cells, Cultured; Ceramides; Dose-Response Relationship, Drug; Endothelium, Vascular; Glutathione; Hypoxanthine; Kidney Glomerulus; Naphthoquinones; Superoxides; Vitamin K; Xanthine Oxidase | 2001 |
Association of quinone-induced platelet anti-aggregation with cytotoxicity.
Topics: Animals; Blood Platelets; Cell Survival; Chloranil; Dinitrochlorobenzene; Dithiothreitol; Female; Glutathione; L-Lactate Dehydrogenase; Naphthoquinones; Platelet Aggregation; Proteins; Rats; Rats, Sprague-Dawley; Sulfhydryl Compounds; Vitamin K | 2001 |
Generation of oxygen free radicals in thyroid cells and inhibition of thyroid peroxidase.
Topics: Animals; Cells, Cultured; Hydrogen Peroxide; Iodide Peroxidase; Naphthoquinones; Reactive Oxygen Species; Superoxides; Swine; Thyroid Gland; Vitamin K 3 | 2002 |
Cross-talk between nitric oxide and superoxide determines ceramide formation and apoptosis in glomerular cells.
Topics: Animals; Apoptosis; Cattle; Cells, Cultured; Ceramides; DNA Fragmentation; Dose-Response Relationship, Drug; Drug Synergism; Kidney Glomerulus; Molsidomine; Naphthoquinones; Nitric Oxide; Nitric Oxide Donors; Spermine; Superoxides | 2002 |
The inherent cellular level of reactive oxygen species: one of the mechanisms determining apoptotic susceptibility of leukemic cells to arsenic trioxide.
Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Cell Separation; Dose-Response Relationship, Drug; Flow Cytometry; Humans; In Situ Nick-End Labeling; Leukemia, Myeloid; Naphthoquinones; Oxides; Reactive Oxygen Species; Tumor Cells, Cultured | 2002 |
[Ascorbic acid enhances the apoptosis of U937 cells induced by arsenic trioxide in combination with DMNQ and its mechanism].
Topics: Apoptosis; Arsenic Trioxide; Arsenicals; Ascorbic Acid; Drug Synergism; Flow Cytometry; Humans; Naphthoquinones; Oxides; U937 Cells | 2002 |
Oxidative stress increases eukaryotic initiation factor 4E phosphorylation in vascular cells.
Topics: Animals; Antioxidants; Cells, Cultured; DNA; Endothelium, Vascular; Eukaryotic Initiation Factor-4E; Humans; Hydrogen Peroxide; Linoleic Acids; Lipid Peroxides; Lipoproteins, LDL; Macromolecular Substances; Macrophages; Myocytes, Smooth Muscle; Naphthoquinones; Oxidants; Oxidative Stress; Phosphorylation; Protein Biosynthesis; Rabbits; Reactive Oxygen Species | 2003 |
A549 subclones demonstrate heterogeneity in toxicological sensitivity and antioxidant profile.
Topics: Adenocarcinoma; Aldehydes; Anisomycin; Antioxidants; Apoptosis; Caspases; Cytotoxins; Dactinomycin; Genetic Heterogeneity; Glutathione; Growth Inhibitors; Humans; Hydrogen Peroxide; Lung Neoplasms; Male; Naphthoquinones; Oxidation-Reduction; Oxidative Stress; Protein Synthesis Inhibitors; Superoxide Dismutase; Tumor Cells, Cultured | 2002 |
Involvement of reactive oxygen species on gentamicin-induced mesangial cell activation.
Topics: Animals; Anti-Bacterial Agents; Catalase; Cell Division; Cell Membrane; Cells, Cultured; Female; Gene Expression Regulation, Enzymologic; Gentamicins; Glomerular Mesangium; Hydrogen Peroxide; Lipid Peroxidation; Membrane Fluidity; NADPH Oxidases; Naphthoquinones; Nitric Oxide Synthase; Rats; Rats, Wistar; Reactive Oxygen Species; RNA, Messenger; Superoxide Dismutase | 2002 |
Autoxidation of extracellular hydroquinones is a causative event for the cytotoxicity of menadione and DMNQ in A549-S cells.
Topics: Buthionine Sulfoximine; Cell Survival; Clone Cells; Humans; Hydrogen Peroxide; Hydroquinones; Lung; Naphthoquinones; Oxidation-Reduction; Reactive Oxygen Species; Respiratory Mucosa; Vitamin K 3 | 2003 |
Discriminating redox cycling and arylation pathways of reactive chemical toxicity in trout hepatocytes.
Topics: Adenine; Animals; Benzoquinones; Cell Death; Female; Glutathione; Glutathione Disulfide; Hepatocytes; Male; Molecular Structure; Naphthoquinones; Oncorhynchus mykiss; Oxidation-Reduction; Oxygen; Pyridines; Quantitative Structure-Activity Relationship; Reactive Oxygen Species; Sulfhydryl Compounds; Vitamin K 3 | 2003 |
Reactive quinones differentially regulate SAPK/JNK and p38/mHOG stress kinases.
Topics: Animals; Antifibrinolytic Agents; Dicumarol; Dose-Response Relationship, Drug; Electrons; Enzyme Activation; Enzyme Inhibitors; Hydrogen Peroxide; Mice; Mitogen-Activated Protein Kinases; Naphthoquinones; NIH 3T3 Cells; Osmosis; Oxidation-Reduction; p38 Mitogen-Activated Protein Kinases; Protein Isoforms; Quinones; Uncoupling Agents; Vitamin K 3 | 2003 |
Oxidative stress in cultured cerebral endothelial cells induces chromosomal aberrations, micronuclei, and apoptosis.
Topics: Animals; Apoptosis; Blotting, Western; Cells, Cultured; Chromosome Aberrations; Endothelium, Vascular; Glucose; Hypoxia; L-Lactate Dehydrogenase; Micronuclei, Chromosome-Defective; Naphthoquinones; Oxidative Stress; Rats; Reperfusion Injury; Swine; Telencephalon; Time Factors; Tumor Suppressor Protein p53 | 2003 |
Epidermal growth factor receptor is a common mediator of quinone-induced signaling leading to phosphorylation of connexin-43: role of glutathione and tyrosine phosphatases.
Topics: Animals; Benzoquinones; Blotting, Western; Cell Line; Connexin 43; Dose-Response Relationship, Drug; Epithelial Cells; ErbB Receptors; Gap Junctions; Glutathione; HeLa Cells; Humans; Immunohistochemistry; Indicators and Reagents; Liver; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Models, Biological; Naphthoquinones; Oxidation-Reduction; Phosphorylation; Precipitin Tests; Rats; Signal Transduction; Time Factors; Ultraviolet Rays; Vitamin K 3 | 2003 |
Inhibitory effect of a naphthazarin derivative, S64, on heat shock factor (Hsf) activation and glutathione status following hypoxia.
Topics: Animals; Antineoplastic Agents; Blotting, Western; Cell Line, Tumor; Cell Nucleus; DNA; Glutamate-Cysteine Ligase; Glutathione; HSP70 Heat-Shock Proteins; Hypoxia; Mice; Naphthoquinones; Protein Binding; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA; Time Factors | 2003 |
Variable regulation of glutamate cysteine ligase subunit proteins affects glutathione biosynthesis in response to oxidative stress.
Topics: Aldehydes; Antioxidants; Bronchi; Epithelium; Glutamate-Cysteine Ligase; Glutathione; Humans; Hydroquinones; Naphthoquinones; Oxidative Stress | 2004 |
The cell cycle related apoptotic susceptibility to arsenic trioxide is associated with the level of reactive oxygen species.
Topics: Acetylcysteine; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Catalase; Cell Cycle; Cell Division; Cell Line, Tumor; Dactinomycin; Flow Cytometry; Fluoresceins; Humans; In Situ Nick-End Labeling; Interphase; Naphthoquinones; Oxides; Propidium; Reactive Oxygen Species | 2004 |
Role of myoglobin in the antioxidant defense of the heart.
Topics: Adenosine Triphosphate; Animals; Free Radical Scavengers; Heart Ventricles; Hydrogen Peroxide; Hydrogen-Ion Concentration; Mice; Mice, Knockout; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Myoglobin; Naphthoquinones; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction; Oxidative Stress; Perfusion; Reactive Oxygen Species; Superoxides | 2004 |
Differential regulation of the mitochondrial and death receptor pathways in neural stem cells.
Topics: Amino Acid Chloromethyl Ketones; Animals; Annexin A5; Antibodies, Monoclonal; Benzimidazoles; Blotting, Western; Caspase Inhibitors; Caspases; Cell Death; Cell Differentiation; Cell Line; Chromatin; Coumarins; Cytochromes c; Drug Interactions; Electrophoresis, Gel, Pulsed-Field; Enzyme Inhibitors; fas Receptor; Flavonoids; Fluorescent Dyes; Free Radical Scavengers; Immunohistochemistry; Metalloporphyrins; Mice; Mitochondria; Mitogen-Activated Protein Kinases; Naphthoquinones; Neurons; Oligopeptides; Propidium; Staurosporine; Stem Cells; Subcellular Fractions; Time Factors | 2004 |
Effect of oxidative stress on the junctional proteins of cultured cerebral endothelial cells.
Topics: Animals; beta Catenin; Blood-Brain Barrier; Cadherins; Capillary Permeability; Cell Survival; Cells, Cultured; Cytoskeletal Proteins; Electric Impedance; Endothelial Cells; Extracellular Signal-Regulated MAP Kinases; Glucose; MAP Kinase Signaling System; Membrane Proteins; Mice; Naphthoquinones; Occludin; Oxidative Stress; Tight Junctions; Trans-Activators | 2005 |
Superoxide targets calcineurin signaling in vascular endothelium.
Topics: Animals; Calcineurin; Cattle; Cells, Cultured; Dose-Response Relationship, Drug; Endothelial Cells; Humans; Naphthoquinones; Signal Transduction; Superoxide Dismutase; Superoxides | 2005 |
NO restores HIF-1alpha hydroxylation during hypoxia: role of reactive oxygen species.
Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Acetylcysteine; Carcinoma, Hepatocellular; Cell Line; Humans; Hydroxylation; Hypoxia; Naphthoquinones; Nitric Oxide; Nitric Oxide Donors; Procollagen-Proline Dioxygenase; Reactive Oxygen Species; Triazenes; Tumor Cells, Cultured; Von Hippel-Lindau Tumor Suppressor Protein | 2005 |
Experimental support for the "E pathway hypothesis" of coupled transmembrane e- and H+ transfer in dihemic quinol:fumarate reductase.
Topics: Cell Membrane; Crystallography, X-Ray; Electrochemistry; Electron Transport; Electrons; Glutamic Acid; Hydrogen-Ion Concentration; Intracellular Membranes; Kinetics; Membrane Potentials; Models, Biological; Models, Chemical; Models, Molecular; Models, Statistical; Models, Theoretical; Molecular Conformation; Naphthoquinones; Oxidation-Reduction; Oxidoreductases; Oxygen; Protein Conformation; Protons; Solvents; Spectrophotometry; Wolinella | 2005 |
Beta-carotene breakdown products enhance genotoxic effects of oxidative stress in primary rat hepatocytes.
Topics: Animals; beta Carotene; Chromosome Aberrations; DNA Damage; Dose-Response Relationship, Drug; Female; Hepatocytes; Hypoxia; Metaphase; Naphthoquinones; Oxidative Stress; Oxygen; Rats; Rats, Inbred F344 | 2006 |
Enhancement of DMNQ-induced hepatocyte toxicity by cytochrome P450 inhibition.
Topics: Animals; Antioxidants; Benzoquinones; Catecholamines; Cell Survival; Cytochrome P-450 Enzyme Inhibitors; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Glutathione Disulfide; Hepatocytes; Imidazolines; Iron Chelating Agents; Ketoconazole; L-Lactate Dehydrogenase; Lipid Peroxidation; Male; Metyrapone; Molecular Structure; NADP; Naphthoquinones; Oxidative Stress; Proadifen; Rats; Rats, Wistar; Superoxides; Thiobarbituric Acid Reactive Substances | 2006 |
Oxidative stress induces internalization of the bile salt export pump, Bsep, and bile salt secretory failure in isolated rat hepatocyte couplets: a role for protein kinase C and prevention by protein kinase A.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Bucladesine; Calcium; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Hepatocytes; Male; Naphthoquinones; Oxidative Stress; Protein Kinase C; Rats; Rats, Wistar; tert-Butylhydroperoxide | 2006 |
Oxidative stress promotes polarization of human T cell differentiation toward a T helper 2 phenotype.
Topics: Cell Differentiation; Cells, Cultured; Cytokines; Humans; Immunophenotyping; Jurkat Cells; Naphthoquinones; Oxidative Stress; Phosphorylation; Receptors, Chemokine; STAT6 Transcription Factor; Th2 Cells | 2006 |
Synthesis and evaluation of antitumor activity of novel 1,4-naphthoquinone derivatives (IV).
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Male; Mice; Mice, Inbred ICR; Naphthoquinones; Neoplasm Transplantation; Sarcoma 180; Structure-Activity Relationship | 2006 |
Reactive oxygen species attenuate nitric-oxide-mediated hypoxia-inducible factor-1alpha stabilization.
Topics: Acetylcysteine; Active Transport, Cell Nucleus; Apoptosis; Catalase; Cell Extracts; Cell Line; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Naphthoquinones; Nitric Oxide; Peroxynitrous Acid; Protein Biosynthesis; Reactive Oxygen Species; Time Factors; Transcriptional Activation | 2006 |
Astrocytes are more resistant than cerebral endothelial cells toward geno- and cytotoxicity mediated by short-term oxidative stress.
Topics: Analysis of Variance; Animals; Animals, Newborn; Apoptosis; Astrocytes; Cell Death; Cells, Cultured; Cerebral Cortex; Endothelial Cells; Glucose; Mice; Naphthoquinones; Necrosis; Oxidative Stress; Time Factors | 2006 |
Classification of heavy-metal toxicity by human DNA microarray analysis.
Topics: Cell Line, Tumor; Cluster Analysis; Gene Expression Profiling; Gene Expression Regulation; Humans; Metals, Heavy; Naphthoquinones; Oligonucleotide Array Sequence Analysis; Phenol; Principal Component Analysis | 2007 |
Effect of nicotine and polyaromtic hydrocarbons on cerebral endothelial cells.
Topics: Animals; beta Catenin; Blood-Brain Barrier; Cadherins; Cerebral Cortex; Claudin-5; Coculture Techniques; Endothelial Cells; Membrane Proteins; Molecular Sequence Data; Naphthoquinones; Neuroglia; Nicotine; Nicotinic Agonists; Occludin; Oxidative Stress; Phenanthrenes; Phosphoproteins; Polycyclic Aromatic Hydrocarbons; Proteome; Rats; Rats, Wistar; Zonula Occludens-1 Protein; Zonula Occludens-2 Protein | 2008 |
Uncoupling protein-2 accumulates rapidly in the inner mitochondrial membrane during mitochondrial reactive oxygen stress in macrophages.
Topics: Antimycin A; Ditiocarb; Hydrogen Peroxide; Ion Channels; Macrophages; Membrane Potential, Mitochondrial; Mitochondrial Membranes; Mitochondrial Proteins; Naphthoquinones; Oxidative Stress; Reactive Oxygen Species; RNA, Messenger; Rotenone; Uncoupling Protein 2 | 2008 |
Caspase-2 activation in neural stem cells undergoing oxidative stress-induced apoptosis.
Topics: Animals; Apoptosis; Cysteine Endopeptidases; Embryonic Stem Cells; Enzyme Activation; Naphthoquinones; Neurons; Oxidative Stress; Rats; Tumor Suppressor Protein p53; Up-Regulation | 2008 |
Kinase activity, heat shock protein 27 phosphorylation, and lung epithelial cell glutathione.
Topics: Adenocarcinoma, Papillary; Cell Line, Tumor; Enzyme Inhibitors; Epithelial Cells; Glutathione; Glutathione Disulfide; Humans; Imidazoles; Intracellular Signaling Peptides and Proteins; Lung Neoplasms; Naphthoquinones; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Pyridines; Respiratory Mucosa; Transfection | 2008 |
Identification of a protective role for protein phosphatase 1cgamma1 against oxidative stress-induced vascular smooth muscle cell apoptosis.
Topics: Animals; Apoptosis; Drug Resistance; Gene Expression Regulation; Gene Library; Gene Silencing; Heart; Humans; Hydrogen Peroxide; Membrane Potentials; Mice; Mice, Inbred C57BL; Mitochondria; Muscle, Smooth, Vascular; Naphthoquinones; Oxidants; Oxidative Stress; Proteasome Endopeptidase Complex; Protein Phosphatase 1; Reactive Oxygen Species; RNA, Small Interfering; Signal Transduction | 2008 |
Evaluation of genotoxic and cytotoxic effects of H2O2 and DMNQ on freshly isolated rat hepatocytes; protective effects of carboxymethyl chitin-glucan.
Topics: Animals; Antioxidants; Apoptosis; Cell Count; Cell Death; Cell Separation; Chitin; Comet Assay; DNA; DNA Damage; Female; Glucans; Hepatocytes; Hydrogen Peroxide; Mutagenicity Tests; Mutagens; Naphthoquinones; Necrosis; Oxidants; Protective Agents; Rats; Rats, Inbred F344 | 2008 |
Modulation of intracellular iron levels by oxidative stress implicates a novel role for iron in signal transduction.
Topics: Apoptosis; Blotting, Western; HeLa Cells; Humans; Iron; MAP Kinase Kinase 4; Naphthoquinones; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Signal Transduction; Vitamin K 3; Vitamins | 2009 |
Pivotal role for two electron reduction in 2,3-dimethoxy-1,4-naphthoquinone and 2-methyl-1,4-naphthoquinone metabolism and kinetics in vivo that prevents liver redox stress.
Topics: Animals; Chromatography, Liquid; Creatinine; Electrons; Liver; Male; Metabolomics; Mice; Mice, Inbred C57BL; Naphthoquinones; Oxidative Stress; Tandem Mass Spectrometry; Tissue Distribution; Transcription, Genetic; Vitamin K 3 | 2009 |
Differential effects of redox-cycling and arylating quinones on trans-plasma membrane electron transport.
Topics: Animals; Benzoquinones; Cell Line, Tumor; Cell Membrane; Cell Survival; Electron Transport; Mice; Naphthoquinones; Oxidation-Reduction; Quinones; Vitamin K 3 | 2008 |
Lysine-91 of the tetraheme c-type cytochrome CymA is essential for quinone interaction and arsenate respiration in Shewanella sp. strain ANA-3.
Topics: Amino Acid Sequence; Arsenate Reductases; Arsenates; Bacterial Proteins; Cell Membrane; Cytochrome c Group; Electron Transport; Escherichia coli; Hydroxyquinolines; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Naphthoquinones; Oxidation-Reduction; Shewanella | 2009 |
The in vitro effects of superoxide, some commercially available antioxidants and red palm oil on sperm motility.
Topics: Antioxidants; Humans; Male; Metalloporphyrins; Naphthoquinones; Palm Oil; Plant Oils; Sperm Motility; Superoxides; Young Adult | 2009 |
Redox modulation of global phosphatase activity and protein phosphorylation in intact skeletal muscle.
Topics: Animals; Dose-Response Relationship, Drug; Hydrogen Peroxide; In Vitro Techniques; Kinetics; Male; Muscle Contraction; Muscle Proteins; Muscle, Skeletal; Naphthoquinones; Oxidants; Oxidation-Reduction; Oxidative Stress; Phosphoprotein Phosphatases; Phosphorylation; Protein Carbonylation; Protein Tyrosine Phosphatases; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction | 2009 |
Resveratrol reduces endothelial oxidative stress by modulating the gene expression of superoxide dismutase 1 (SOD1), glutathione peroxidase 1 (GPx1) and NADPH oxidase subunit (Nox4).
Topics: Antioxidants; Blotting, Western; Cells, Cultured; Endothelial Cells; Endothelium, Vascular; Gene Expression Regulation, Enzymologic; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Humans; NADPH Oxidase 4; NADPH Oxidases; Naphthoquinones; Oxidative Stress; Reactive Oxygen Species; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stilbenes; Superoxide Dismutase; Superoxide Dismutase-1 | 2009 |
Crucial role of cytochrome P450 in hepatotoxicity induced by 2,3-dimethoxy-1,4-naphthoquinone in rats.
Topics: alpha-Tocopherol; Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Cimetidine; Cytochrome P-450 Enzyme Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Glutathione; Ketoconazole; Lipid Peroxidation; Liver; Male; Naphthoquinones; Oxidation-Reduction; Oxidative Stress; Proadifen; Rats; Rats, Wistar; Substrate Cycling | 2011 |
Glucocorticoids induce long-lasting effects in neural stem cells resulting in senescence-related alterations.
Topics: Animals; Cell Proliferation; Cellular Senescence; Chromobox Protein Homolog 5; Chromosomal Proteins, Non-Histone; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinase Inhibitor p21; Cytochromes b; Dexamethasone; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Epigenesis, Genetic; Glucocorticoids; Mitochondria; NADH Dehydrogenase; Naphthoquinones; Neural Stem Cells; Nuclear Proteins; Polycomb Repressive Complex 1; Proto-Oncogene Proteins; Rats; Receptors, Glucocorticoid; Repressor Proteins | 2010 |
Dexamethasone enhances oxidative stress-induced cell death in murine neural stem cells.
Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Blotting, Western; Caspase 3; Cell Cycle; Cell Death; Cell Line; Cell Nucleus; Dexamethasone; Electron Transport; Flow Cytometry; G1 Phase; Gene Expression; Mice; Mifepristone; Naphthoquinones; Neural Stem Cells; Oxidative Stress; Real-Time Polymerase Chain Reaction; Receptors, Glucocorticoid; Trypan Blue | 2012 |
Effects of Salvia officinalis and Thymus vulgaris on oxidant-induced DNA damage and antioxidant status in HepG2 cells.
Topics: Antioxidants; DNA Damage; Glutathione; Glutathione Peroxidase; Hep G2 Cells; Humans; Hydrogen Peroxide; Naphthoquinones; Oxidants; Plant Extracts; Salvia officinalis; Superoxide Dismutase; Thymus Plant | 2013 |
Nitrosative stress and redox-cycling agents synergize to cause mitochondrial dysfunction and cell death in endothelial cells.
Topics: Animals; Aorta; Cattle; Cell Death; Cells, Cultured; Cysteine; Drug Synergism; Endothelial Cells; Mitochondria; Naphthoquinones; Nitrosation; Reactive Oxygen Species; S-Nitrosothiols | 2013 |
Inhibitory effects of LPA1 on cell motile activities stimulated by hydrogen peroxide and 2,3-dimethoxy-1,4-naphthoquinone in fibroblast 3T3 cells.
Topics: 3T3 Cells; Animals; Cell Line, Tumor; Cell Movement; Cell Proliferation; Diphosphates; Fibroblasts; Gene Expression Regulation; Glycerol; Hydrogen Peroxide; Lysophospholipids; Mice; Naphthoquinones; Neuroblastoma; Rats; Receptors, Lysophosphatidic Acid | 2013 |
Oxidative stress induces mitochondrial dysfunction in a subset of autism lymphoblastoid cell lines in a well-matched case control cohort.
Topics: Autistic Disorder; Case-Control Studies; Cell Line; Cell Respiration; Child; Child, Preschool; Female; Glycolysis; Humans; Ion Channels; Lymphocytes; Male; Mitochondria; Mitochondrial Membranes; Mitochondrial Proteins; Naphthoquinones; Oxidation-Reduction; Oxidative Stress; Protons; Reactive Oxygen Species; Uncoupling Protein 2 | 2014 |
Reactive oxygen species prevent imiquimod-induced psoriatic dermatitis through enhancing regulatory T cell function.
Topics: Acetylcysteine; Aminoquinolines; Animals; Dermatitis; Disease Progression; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Hyperbaric Oxygenation; Imiquimod; Indoleamine-Pyrrole 2,3,-Dioxygenase; Mice, Inbred C57BL; NADPH Oxidases; Naphthoquinones; Psoriasis; Reactive Oxygen Species; T-Lymphocytes, Regulatory | 2014 |
Suppression of soluble adenylyl cyclase protects smooth muscle cells against oxidative stress-induced apoptosis.
Topics: Adenylyl Cyclases; Animals; Animals, Newborn; Antioxidants; Apoptosis; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Hydrogen Peroxide; Mitochondria; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Naphthoquinones; Oxidants; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Phosphatase 1; Rats; Signal Transduction | 2014 |
Oxidative stress modulates the expression of genes involved in cell survival in ΔF508 cystic fibrosis airway epithelial cells.
Topics: Apoptosis; Caspase 3; Caspase 7; Cell Line; Cell Survival; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Down-Regulation; Epithelial Cells; Gene Expression Profiling; Gene Expression Regulation; Gene Ontology; Humans; Inflammation; Lung; Naphthoquinones; Oxidative Stress; Reproducibility of Results; RNA, Messenger; Up-Regulation | 2014 |
Label free high throughput screening for apoptosis inducing chemicals using time-lapse microscopy signal processing.
Topics: Antibiotics, Antineoplastic; Apoptosis; Caspase 3; Caspase 7; HCT116 Cells; High-Throughput Screening Assays; Humans; Microscopy; Mitomycin; Naphthoquinones; Organic Chemicals; Piperidines; Staining and Labeling; Time-Lapse Imaging | 2014 |
Acute ethanol induces apoptosis by stimulating TRPC6 via elevation of superoxide in oxygenated podocytes.
Topics: Apoptosis; Catalase; Cell Line; Cell Membrane; Ethanol; Humans; Hydrogen Peroxide; Intracellular Space; Ion Channel Gating; Membrane Glycoproteins; NADPH Oxidase 2; NADPH Oxidases; Naphthoquinones; Oxidative Stress; Oxygen; Podocytes; Protein Transport; Superoxides; TRPC Cation Channels; TRPC6 Cation Channel | 2015 |
Inhibition of the lymphocyte metabolic switch by the oxidative burst of human neutrophils.
Topics: Cells, Cultured; Coculture Techniques; Glycolysis; Humans; Hydrogen Peroxide; Immunity, Innate; Lymphocytes; Naphthoquinones; Neutrophil Activation; Neutrophils; Oxidation-Reduction; Peroxidase; Respiratory Burst; Superoxides; Suppressor Factors, Immunologic; T-Lymphocyte Subsets | 2015 |
The Bioenergetic Health Index is a sensitive measure of oxidative stress in human monocytes.
Topics: Adult; Biomarkers; Energy Metabolism; Female; Humans; Male; Mitochondria; Monocytes; Naphthoquinones; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species | 2016 |
High glucose-induced oxidative stress represses sirtuin deacetylase expression and increases histone acetylation leading to neural tube defects.
Topics: Acetylation; Animals; Diabetes, Gestational; Epigenesis, Genetic; Female; Glucose; Group III Histone Deacetylases; Heterocyclic Compounds, 4 or More Rings; Histones; Mice; Naphthoquinones; Neural Stem Cells; Neural Tube Defects; Oxidative Stress; Pregnancy; Sirtuin 2; Sirtuins; Superoxide Dismutase; Superoxide Dismutase-1 | 2016 |
l-Serine protects mouse hippocampal neuronal HT22 cells against oxidative stress-mediated mitochondrial damage and apoptotic cell death.
Topics: Animals; Antioxidants; Apoptosis; Cell Line; Endoplasmic Reticulum Stress; Hippocampus; Membrane Potential, Mitochondrial; Mice; Mitochondria; Naphthoquinones; Neurons; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protective Agents; Reactive Oxygen Species; Serine | 2019 |
GSK3β is a key regulator of the ROS-dependent necrotic death induced by the quinone DMNQ.
Topics: Cell Line; Cell Nucleus; Enzyme Activation; Genetic Testing; Glycogen Synthase Kinase 3 beta; Green Fluorescent Proteins; Humans; Membrane Potential, Mitochondrial; Mitochondria; Models, Biological; Naphthoquinones; Necroptosis; NF-E2-Related Factor 2; Oxidative Stress; Reactive Oxygen Species; Reproducibility of Results; RNA, Small Interfering | 2020 |