2,3-dihydroxybenzoic acid has been researched along with hydroxyl radical in 162 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (1.23) | 18.7374 |
| 1990's | 88 (54.32) | 18.2507 |
| 2000's | 68 (41.98) | 29.6817 |
| 2010's | 4 (2.47) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bredl, CR; Foerder, CA; Gmur, DJ; Schimpf, BA; Zager, RA | 1 |
| Cavallo, G; Chessa, MA; Milazzotto, F; Natale, E; Pensa, V; Ricci, R; Tubaro, E; Tubaro, M | 1 |
| Ariel, I; Chevion, M; Haskel, Y; Kitrossky, N; Udassin, R | 1 |
| Ashraf, M; Onodera, T | 1 |
| Hall, D; Powell, SR | 1 |
| Floyd, RA; Henderson, R; Watson, JJ; Wong, PK | 1 |
| Grootveld, M; Halliwell, B | 1 |
| Alonso, O; Busto, R; Dietrich, WD; Ginsberg, MD; Globus, MY | 1 |
| Kuo, JS; Lin, NN; Liu, L; Tsai, PJ; Yang, CS | 1 |
| Himori, N; Suzuki, T; Ueno, K | 1 |
| Busto, R; Ginsberg, MD; Globus, MY; Lin, B; Schnippering, H | 1 |
| Coudray, C; Fatôme, M; Favier, A; Martin, S; Talla, M | 1 |
| Ashraf, M; Cai, Q; Takemura, G | 1 |
| Naoi, M; Ohkuwa, T; Sato, Y | 1 |
| Király, I; Patthy, M; Sziráki, I | 1 |
| Piantadosi, CA; Zhang, J | 2 |
| Ito, T; Kondo, T; Sugita, Y | 1 |
| Laxdal, VA; Prasad, K | 2 |
| Ghio, AJ; Piantadosi, CA; Taylor, DE | 1 |
| Hosokawa, H; Karashima, K; Obata, T; Soeda, T; Uchida, Y; Yamanaka, Y | 1 |
| Almagro, UA; Dawson, CA; Effros, RM; Ghio, AJ; Hacker, AD; Morrisey, J; Schapira, RM | 1 |
| Cross, M; Endre, ZH; Kadkhodaee, M; Towner, RA | 1 |
| Giovanni, A; Hastings, TG; Liang, LP; Zigmond, MJ | 1 |
| Hosokawa, H; Obata, T; Yamanaka, Y | 2 |
| Okuyama, T; Tomita, M; Watanabe, H; Watanabe, S | 1 |
| Itokawa, Y; Kondo, H; Nishino, K | 1 |
| Averbukh, E; Berenshtein, E; Kitrossky, N; Ophir, A | 1 |
| Andrus, PK; Hall, ED; Zhang, JR | 2 |
| Clanton, TL; Davis, WB; Diaz, PT; She, ZW | 1 |
| Floyd, RA; Grammas, P; Liu, GJ; Wood, K | 1 |
| Ashraf, M; Millard, RW; Onodera, T; Takemura, G | 1 |
| Zager, RA | 1 |
| Kil, HY; Piantadosi, CA; Zhang, J | 1 |
| Gramsbergen, JB; Sloot, WN | 1 |
| Boulu, RG; Callebert, J; Lancelot, E; Plotkine, M; Revaud, ML | 2 |
| Kim, PM; Wells, PG | 1 |
| Laxdal, VA; Prasad, K; Raney, BL; Yu, M | 2 |
| Kanazawa, A; Kondo, T | 1 |
| Hirata, T; Obata, T; Uchida, Y; Yamanaka, Y | 1 |
| Demchenko, IT; Piantadosi, CA; Zhang, J | 1 |
| Böning, J; Davids, E; Foley, P; Gerlach, M; Riederer, P; Thome, J; Weijers, HG; Wiesbeck, GA; Zhang, J | 1 |
| Chevion, M; Drenger, B; Elami, A; Ginosar, Y; Glantz, L; Gozal, Y; Kitrossky, N; Navot, N | 1 |
| Prasad, K | 1 |
| Piantadosi, CA; Tatro, L; Zhang, J | 1 |
| Chevion, M; Grinberg, LN; Kitrossky, N; Rachmilewitz, EA | 1 |
| Acworth, IN; Maher, TJ; McCabe, DR | 1 |
| Obata, T; Yamanaka, Y | 7 |
| Obata, T; Tamura, M; Yamanaka, Y | 2 |
| Obata, T | 5 |
| Kogure, K; Mitsuka, M; Saito, KI; Watanabe, T; Yamamoto, T; Yuki, S | 1 |
| Huang, NC; Quast, MJ; Wei, J | 1 |
| Huang, NK; Tseng, CJ; Tung, CS; Wan, FJ | 1 |
| Ferger, B; Kuschinsky, K; Seyfried, C; van Amsterdam, C | 1 |
| Mizuno, A; Nakashima, M; Umemura, K | 1 |
| Boulu, RG; Callebert, J; Lancelot, E; Lecanu, L; Plotkine, M; Revaud, ML | 1 |
| Lee, KT; Liu, TZ; Tsai, LY | 1 |
| Hatori, K; Kondo, T; Mizuno, Y; Shimada, H; Sugita, Y | 1 |
| Blackburn, AC; Buffinton, GD; Doe, WF | 1 |
| Cann-Moisan, C; Caroff, J; Duine, JM; Floch, F; Mialon, P | 1 |
| Abin, JA; Costa, G; Dajas, F; Dajas-Bailador, FA; Martignoni, E; Martinez-Borges, A; Nappi, G | 1 |
| Itoh, H; Miyamura, M; Naoi, M; Ohkuwa, T; Sato, Y; Yamamoto, T | 1 |
| Bringmann, G; Feineis, D; Gerlach, M; God, R; Heim, C; Lan, J; Riederer, P; Sontag, KH; Xiao, AY | 1 |
| Hiramatsu, M; Komatsu, M | 1 |
| Acworth, IN; Beal, MF; Bogdanov, MB; McCabe, DR | 1 |
| Natoli, S; Violi, F | 1 |
| Abbott, FS; Tabatabaei, AR | 1 |
| Gudelsky, GA; Shankaran, M; Yamamoto, BK | 2 |
| Hindmarsh, JG; Jenner, P; Rose, S | 1 |
| Aomine, M; Obata, T; Yamanaka, Y | 1 |
| Blandini, F; Desideri, S; Godi, L; Mancini, F; Martignoni, E; Nappi, G; Pacchetti, C | 1 |
| Barbanel, G; Cauquil-Caubère, I; Kamenka, JM; Oxhamre, C | 1 |
| Blandini, F; di Jeso, F; Martignoni, E; Nappi, G; Ricotti, R | 1 |
| Kita, T; Kubo, K; Nakashima, T; Takahashi, M; Wagner, GC | 1 |
| Floyd, RA; He, QP; Li, PA; Liu, GJ; Siesjö, BK | 1 |
| Jantze, H; Rauca, C; Zerbe, R | 1 |
| Benedetti Strolin, M; Tipton, KF | 1 |
| Chen, CF; Cheng, FC; Hung, LC; Tsai, TH | 1 |
| Bartsch, H; Owen, RW; Spiegelhalder, B | 1 |
| Amiridze, N; Brown, OR; Dang, Y | 1 |
| Gronow, G; Mályusz, M; Moussavian, M | 1 |
| Mohanakumar, KP; Muralikrishnan, D; Thomas, B | 2 |
| Camp, DM; LeWitt, PA; Loeffler, DA | 1 |
| Lin, HC; Lin, YS; Tseng, CJ; Wan, FJ | 1 |
| Gerlach, M; Heim, C; Kurz, T; Lan, J; Riederer, P; Sieklucka, M; Sontag, KH; Zhang, J | 1 |
| Almaas, R; Pleasure, D; Rootwelt, T; Saugstad, OD | 1 |
| Hara, A; Kusakari, J; Senarita, M; Serizawa, F; Tabuchi, K | 1 |
| Chevion, M; Kitrossky, N; Zhu, BZ | 1 |
| Ferger, B; Teismann, P | 1 |
| Ebihara, A; Obata, T; Yamanaka, Y | 1 |
| Ding, Y; Gonick, HC; Vaziri, ND | 1 |
| Belcher, JD; Choong, S; Hebbel, RP; Osarogiagbon, UR; Paller, MS; Vercellotti, GM | 1 |
| Acuña-Castroviejo, D; Escames, G; Khaldy, H; León, J; Luna, JD; Vives, F | 1 |
| Barbanel, G; Cambonie, G; Kamenka, JM; Laplanche, L | 1 |
| Brus, R; Kostrzewa, JP; Kostrzewa, RM | 1 |
| Ferger, B; Mierau, J; Teismann, P | 1 |
| Coudray, C; Favier, A | 1 |
| Bennett, PB; Boso, AE; Demchenko, IT; Piantadosi, CA; Whorton, AR | 1 |
| Endo, K; Fujita, S; Gooneratne, R; Hosokawa, T; Kazusaka, A; Mizuno, H; Watanabe, T; Yamamoto, H | 1 |
| Huang, KL; Lin, HC; Tseng, CJ; Wan, FJ; Wong, CS | 1 |
| Chen, YK; Lin, HC; Liu, JC; Wan, FJ | 1 |
| Ferger, B; Halliwell, B; Jenner, A; Jenner, P; Rose, S | 1 |
| Ikeda, K; Nara, Y; Negishi, H; Yamori, Y | 2 |
| Kinemuchi, H; Obata, T; Oreland, L; Yamanaka, Y | 1 |
| Camacho, A; Flores, A; Galván-Arzate, S; Jiménez-Capdeville, ME; Rodríguez-Martínez, E; Santamaría, A | 1 |
| Gorodetskaya, EA; Kalenikova, EI | 1 |
| Akashi, K; Miyake, C; Yokota, A | 1 |
| Kubota, S; Obata, T; Yamanaka, Y | 1 |
| Kamendulis, LM; Klaunig, JE; Zhang, H | 1 |
| Huang, M; Li, Q; Liu, W; Wu, CF | 1 |
| Egashira, T; Obata, T | 1 |
| Ashton, T; Griffiths, RD; Jackson, MJ; McArdle, A; Pattwell, D | 1 |
| Banerjee, R; Mohanakumar, KP; Sairam, K; Saravanan, KS | 1 |
| Horiguchi, T; Inamasu, J; Kawase, T; Ogino, M; Shimizu, K; Suga, S | 1 |
| Beley, A; Bertrand, N; Demougeot, C; Garnier, P; Marie, C; Mossiat, C; Prigent-Tessier, A | 1 |
| Adibhatla, RM; Dempsey, RJ; Hatcher, JF | 1 |
| Hashimoto, T; Nakamura, H; Yonetani, M | 1 |
| Nomoto, N | 1 |
| Gorodetskaya, EA; Kalenikova, EI; Medvedev, OS; Murashev, AN; Ruuge, EK | 1 |
| Endo, T; Hara, S; Kuriiwa, F; Kurosaki, K; Mukai, T | 1 |
| Bryla, J; Drozak, J; Fraczyk, T; Wegrzynowicz, M; Winiarska, K | 1 |
| Berenshtein, E; Chevion, M; Drenger, B; Elami, A; Gozal, Y; Kitrossky, N | 1 |
| Berenshtein, E; Chevion, M; Drenger, B; Gozal, Y; Raphael, J; Rivo, J | 1 |
| Lin, HC; Shiah, IS; Tung, CS; Wan, FJ | 1 |
| Dahchour, A; De Witte, P; Lallemand, F; Ward, RJ | 1 |
| Chang, CP; Huang, WT; Lin, MT | 1 |
| Hayakawa, Y; Masaoka, N; Nagaishi, M; Nakajima, Y; Sakata, H; Watanabe, M; Yamamoto, T | 1 |
| Cao, Y; Tanaka, M; Wu, CF; Wu, YL; Yao, WX; Zuo, DY | 1 |
| Ito, N; Kashimoto, T; Nishimura, Y; Sugiyama, M; Susa, N; Takeda-Homma, S; Ueno, S; Wada, K | 1 |
| Arai, M; Bao, N; Chen, XH; Fujiwara, H; Kawamura, I; Kobayashi, H; Lu, C; Minatoguchi, S; Takemura, G; Wang, N; Wu, DJ; Yasuda, S | 1 |
| Huang, WT; Kao, CH; Kao, TY; Lin, MT | 1 |
| Cho, KO; Choi, YS; Kim, EJ; Kim, SY; Sung, KW | 1 |
| Dadjour, MF; Fujihira, A; Ninomiya, K; Ogino, C; Sakiyama, K; Shimizu, N | 1 |
| Kashiwagi, Y; Kubota, S; Obata, T; Takahashi, S | 1 |
| Aomine, M; Obata, T; Yonemoti, H | 1 |
| Endo, T; Hara, S; Kuriiwa, F; Mizukami, H | 1 |
| Bao, N; Fujiwara, H; Fujiwara, T; Iwasa, M; Kawamura, I; Kobayashi, H; Minatoguchi, S; Nishigaki, K; Sumi, S; Takemura, G; Yamada, Y; Yasuda, S; Zhang, Z | 1 |
| Cox, DP; Diaz, AA; Mackey, MM; Thomas, C | 1 |
| Endo, T; Hara, S; Kuriiwa, F; Kurosaki, K; Mizukami, H; Mukai, T | 1 |
| Bosco, GM; Camporesi, EM; Chen, C; Xie, Y; Yang, ZJ | 1 |
| Huang, WT; Kao, CH; Lin, MT; Wu, WS | 1 |
| Hara, S; Kobayashi, M; Kuriiwa, F; Mizukami, H; Mukai, T | 1 |
| Nakashima, M; Obata, T | 1 |
2 trial(s) available for 2,3-dihydroxybenzoic acid and hydroxyl radical
| Article | Year |
|---|---|
Peripheral markers of oxidative stress in Parkinson's disease. The role of L-DOPA.
Topics: Antiparkinson Agents; Biomarkers; Blood Platelets; Dopamine; Female; Gentisates; Humans; Hydroxybenzoates; Hydroxyl Radical; In Vitro Techniques; Levodopa; Linear Models; Male; Middle Aged; Oxidative Stress; Parkinson Disease; Sodium Salicylate; Superoxide Dismutase; Tyrosine | 1999 |
Determination of hydroxyl free radical formation in human platelets using high-performance liquid chromatography with electrochemical detection.
Topics: Adult; Antiparkinson Agents; Blood Platelets; Chromatography, High Pressure Liquid; Electrochemistry; Female; Humans; Hydroxybenzoates; Hydroxyl Radical; Levodopa; Male; Middle Aged; Parkinson Disease; Tyrosine | 1999 |
160 other study(ies) available for 2,3-dihydroxybenzoic acid and hydroxyl radical
| Article | Year |
|---|---|
Evidence against increased hydroxyl radical production during oxygen deprivation-reoxygenation proximal tubular injury.
Topics: Acute Kidney Injury; Animals; Free Radicals; Gentisates; Hydroxides; Hydroxybenzoates; Hydroxyl Radical; Hypoxia; In Vitro Techniques; Kidney Tubules, Proximal; L-Lactate Dehydrogenase; Male; Rats; Rats, Inbred Strains; Reperfusion Injury | 1992 |
Demonstration of the formation of hydroxyl radicals in acute myocardial infarction in man using salicylate as probe.
Topics: Aspirin; Chromatography, High Pressure Liquid; Female; Free Radicals; Gentisates; Humans; Hydroxides; Hydroxybenzoates; Hydroxyl Radical; Isosorbide Dinitrate; Male; Middle Aged; Myocardial Infarction; Tissue Plasminogen Activator | 1992 |
Salicylate as an in vivo free radical trap: studies on ischemic insult to the rat intestine.
Topics: Animals; Disease Models, Animal; Free Radicals; Gentisates; Hydroxides; Hydroxybenzoates; Hydroxyl Radical; Intestines; Male; Rats; Reperfusion Injury; Salicylates; Salicylic Acid | 1991 |
Detection of hydroxyl radicals in the post-ischemic reperfused heart using salicylate as a trapping agent.
Topics: Animals; Chromatography, High Pressure Liquid; Gentisates; Hydroxides; Hydroxybenzoates; Hydroxyl Radical; Hydroxylation; In Vitro Techniques; Ischemia; Male; Myocardial Reperfusion; Oxygen; Rats; Rats, Inbred Strains; Salicylates; Salicylic Acid | 1991 |
Use of salicylate as a probe for .OH formation in isolated ischemic rat hearts.
Topics: Animals; Chromatography, High Pressure Liquid; Electron Spin Resonance Spectroscopy; Free Radicals; Hydroxides; Hydroxybenzoates; Hydroxyl Radical; Male; Rats; Rats, Inbred Strains; Reperfusion Injury; Salicylates; Salicylic Acid | 1990 |
Use of salicylate with high pressure liquid chromatography and electrochemical detection (LCED) as a sensitive measure of hydroxyl free radicals in adriamycin treated rats.
Topics: Animals; Chromatography, High Pressure Liquid; Doxorubicin; Electrochemistry; Female; Free Radicals; Gentisates; Heart; Hydroxides; Hydroxybenzoates; Hydroxyl Radical; Rats; Rats, Inbred F344; Salicylates; Salicylic Acid | 1986 |
Aromatic hydroxylation as a potential measure of hydroxyl-radical formation in vivo. Identification of hydroxylated derivatives of salicylate in human body fluids.
Topics: Adult; Chromatography, High Pressure Liquid; Electrochemistry; Free Radicals; Gentisates; Hippurates; Humans; Hydroxides; Hydroxybenzoates; Hydroxyl Radical; Hydroxylation; Male; Salicylates; Salicylic Acid; Synovial Fluid | 1986 |
Glutamate release and free radical production following brain injury: effects of posttraumatic hypothermia.
Topics: Animals; Brain Injuries; Free Radicals; Gentisates; Glutamic Acid; Hydroxybenzoates; Hydroxyl Radical; Hypothermia; Male; Microdialysis; Rats; Rats, Sprague-Dawley | 1995 |
Elevated extracellular glutamate levels increased the formation of hydroxyl radical in the striatum of anesthetized rat.
Topics: Anesthesia; Animals; Chromatography, High Pressure Liquid; Corpus Striatum; Extracellular Space; Gentisates; Glutamic Acid; Hydroxybenzoates; Hydroxyl Radical; Hydroxylation; Kinetics; Male; Rats; Rats, Sprague-Dawley; Salicylates; Salicylic Acid | 1995 |
Aniracetam, a pyrrolidinone-type cognition enhancer, attenuates the hydroxyl free radical formation in the brain of mice with brain ischaemia.
Topics: Animals; Brain; Brain Ischemia; Chromatography, High Pressure Liquid; Disease Models, Animal; Dopamine; Hydroxybenzoates; Hydroxyl Radical; Injections, Intraperitoneal; Male; Mice; Pyrrolidinones; Reperfusion Injury | 1995 |
Detection of free radical activity during transient global ischemia and recirculation: effects of intraischemic brain temperature modulation.
Topics: Animals; Body Temperature; Corpus Striatum; Dialysis; Free Radicals; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Ischemic Attack, Transient; Kinetics; Male; Rats; Rats, Wistar; Reperfusion; Salicylates; Salicylic Acid | 1995 |
High-performance liquid chromatography-electrochemical determination of salicylate hydroxylation products as an in vivo marker of oxidative stress.
Topics: Adult; Aspirin; Calibration; Chromatography, High Pressure Liquid; Female; Free Radical Scavengers; Gentisates; Humans; Hydroxybenzoates; Hydroxyl Radical; Male; Oxidative Stress; Reproducibility of Results; Salicylates; Salicylic Acid; Thiobarbituric Acid Reactive Substances | 1995 |
Antioxidative properties of histidine and its effect on myocardial injury during ischemia/reperfusion in isolated rat heart.
Topics: Adenosine Triphosphate; Animals; Ascorbic Acid; Chromatography, High Pressure Liquid; Disease Models, Animal; Free Radical Scavengers; Gentisates; Glutaral; Heart Ventricles; Histidine; Hydrogen Peroxide; Hydroxybenzoates; Hydroxyl Radical; L-Lactate Dehydrogenase; Male; Myocardial Reperfusion Injury; Phosphates; Phosphocreatine; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Superoxides; Tissue Embedding; Ventricular Function, Left | 1995 |
Hydroxyl radical formation in diabetic rats induced by streptozotocin.
Topics: Animals; Blood Glucose; Chromatography, High Pressure Liquid; Diabetes Mellitus, Experimental; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Male; Rats; Rats, Wistar; Streptozocin | 1995 |
Separation of dihydroxybenzoates, indicators of in-vivo hydroxyl free radical formation, in the presence of transmitter amines and some metabolites in rodent brain, using high-performance liquid chromatography with electrochemical detection.
Topics: Animals; Biogenic Amines; Chromatography, High Pressure Liquid; Corpus Striatum; Electrochemistry; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Mice; Mice, Inbred C57BL | 1995 |
Prolonged production of hydroxyl radical in rat hippocampus after brain ischemia-reperfusion is decreased by 21-aminosteroids.
Topics: Animals; Antioxidants; Cerebrovascular Circulation; Hippocampus; Hydroxybenzoates; Hydroxyl Radical; Hydroxylation; Ischemic Attack, Transient; Male; Pregnatrienes; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Salicylates; Salicylic Acid | 1994 |
Bromocriptine scavenges methamphetamine-induced hydroxyl radicals and attenuates dopamine depletion in mouse striatum.
Topics: Animals; Bromocriptine; Corpus Striatum; Dopamine; Free Radical Scavengers; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Iron Chelating Agents; Kinetics; Male; Methamphetamine; Mice; Mice, Inbred C57BL; Salicylates; Salicylic Acid | 1994 |
Evaluation of hydroxyl radical-scavenging property of purpurogallin using high pressure liquid chromatography.
Topics: Antioxidants; Benzocycloheptenes; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Food Preservatives; Free Radical Scavengers; Gentisates; Hydrogen Peroxide; Hydroxybenzoates; Hydroxyl Radical; Hydroxylation; Photolysis; Salicylates; Salicylic Acid; Ultraviolet Rays | 1994 |
Reactive oxygen species produced by liver mitochondria of rats in sepsis.
Topics: Animals; Cell-Free System; Cyanides; Electron Transport; Hydrogen Peroxide; Hydroxybenzoates; Hydroxyl Radical; Iron; Male; Mitochondria, Liver; Oxidative Stress; Oxygen Consumption; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Rotenone; Salicylates; Salicylic Acid; Sepsis; Subcellular Fractions; Succinates; Succinic Acid | 1995 |
Hydroxyl radical-scavenging property of indomethacin.
Topics: Chromatography, High Pressure Liquid; Free Radical Scavengers; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Indomethacin; Photolysis; Sensitivity and Specificity; Ultraviolet Rays | 1994 |
Myocardial microdialysis of salicylic acid to detect hydroxyl radical generation during ischemia.
Topics: Animals; Chromatography, High Pressure Liquid; Dogs; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Microchemistry; Microdialysis; Myocardial Contraction; Myocardial Ischemia; Salicylates; Salicylic Acid | 1995 |
Hydroxyl radical production and lung injury in the rat following silica or titanium dioxide instillation in vivo.
Topics: Animals; Bronchoalveolar Lavage Fluid; Dust; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Hydroxylation; Lung; Lung Injury; Organ Size; Pulmonary Fibrosis; Rats; Rats, Sprague-Dawley; Salicylates; Salicylic Acid; Silicon Dioxide; Silicosis; Titanium | 1995 |
Hydroxyl radical generation following ischaemia-reperfusion in cell-free perfused rat kidney.
Topics: Animals; Chromatography, High Pressure Liquid; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Hypoxia; Ischemia; Kidney; Male; Rats; Rats, Wistar; Reperfusion; Salicylates | 1995 |
Estimating hydroxyl radical content in rat brain using systemic and intraventricular salicylate: impact of methamphetamine.
Topics: Animals; Biogenic Monoamines; Brain; Corpus Striatum; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Hydroxylation; Injections, Intraperitoneal; Injections, Intraventricular; Methamphetamine; Rats; Rats, Sprague-Dawley; Salicylates; Salicylic Acid | 1995 |
In vivo monitoring of norepinephrine and hydroxyl free radical generation by ferrous iron in the myocardium with a microdialysis technique.
Topics: Animals; Chromatography, High Pressure Liquid; Electrochemistry; Ferrous Compounds; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Iron Chelating Agents; Male; Microdialysis; Myocardium; Norepinephrine; Perfusion; Rats; Rats, Wistar | 1993 |
Quantitation of the hydroxyl radical adducts of salicylic acid by micellar electrokinetic capillary chromatography: oxidizing species formed by a Fenton reaction.
Topics: Chromatography; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Iron; Micelles; Salicylates; Salicylic Acid | 1994 |
Hydroxyl radical generation in skeletal muscle atrophied by immobilization.
Topics: Animals; Free Radical Scavengers; Hydroxybenzoates; Hydroxyl Radical; Immobilization; Male; Muscles; Muscular Atrophy; Rats; Rats, Wistar; Salicylates; Salicylic Acid | 1994 |
Protection of the transiently ischemic cat retina by zinc-desferrioxamine.
Topics: Animals; Cats; Deferoxamine; Electroretinography; Fundus Oculi; Hydroxybenzoates; Hydroxyl Radical; Injections, Intravenous; Ischemia; Organometallic Compounds; Reperfusion Injury; Retinal Vessels; Salicylates; Salicylic Acid | 1994 |
In vivo monitoring of norepinephrine and .OH generation on myocardial ischemic injury by dialysis technique.
Topics: Animals; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Microdialysis; Myocardial Ischemia; Myocardial Reperfusion; Norepinephrine; Rats; Rats, Wistar | 1994 |
Age-related phospholipid hydroperoxide levels in gerbil brain measured by HPLC-chemiluminescence and their relation to hydroxyl radical stress.
Topics: Aging; Animals; Antioxidants; Brain Chemistry; Chromatography, High Pressure Liquid; Gerbillinae; Hydroxybenzoates; Hydroxyl Radical; Iron Chelating Agents; Lipid Peroxidation; Luminescent Measurements; Male; Phosphatidylcholines; Stress, Physiological | 1994 |
Hydroxylation of salicylate by the in vitro diaphragm: evidence for hydroxyl radical production during fatigue.
Topics: Animals; Chromatography, High Pressure Liquid; Electric Stimulation; Electrochemistry; Hydroxybenzoates; Hydroxyl Radical; Hydroxylation; In Vitro Techniques; Muscle Contraction; Rats; Rats, Sprague-Dawley; Respiratory Muscles; Salicylates; Salicylic Acid; Spectrophotometry, Ultraviolet | 1993 |
Age-related regional changes in hydroxyl radical stress and antioxidants in gerbil brain.
Topics: Aging; Animals; Antioxidants; Ascorbic Acid; Body Water; Brain; Cerebral Cortex; Corpus Striatum; Gentisates; Gerbillinae; Glutathione; Hippocampus; Hydroxybenzoates; Hydroxyl Radical; Male; Neurons; Organ Specificity; Oxidation-Reduction; Pyramidal Tracts; Vitamin E | 1993 |
Anoxia/reoxygenation induces hydroxyl free radical formation in brain microvessels.
Topics: Animals; Brain; Catalase; Chromatography, High Pressure Liquid; Free Radicals; Gentisates; Hydroxides; Hydroxybenzoates; Hydroxyl Radical; Male; Microcirculation; Oxygen; Rats; Rats, Sprague-Dawley; Salicylates; Salicylic Acid; Superoxides | 1993 |
Demonstration of hydroxyl radical and its role in hydrogen peroxide-induced myocardial injury: hydroxyl radical dependent and independent mechanisms.
Topics: Adenosine Triphosphate; Animals; Catalase; Coronary Circulation; Free Radicals; Heart; Heart Rate; Hydrogen Peroxide; Hydroxides; Hydroxybenzoates; Hydroxyl Radical; Lipid Peroxidation; Male; Microscopy, Electron; Myocardial Contraction; Myocardium; Rats; Rats, Sprague-Dawley; Thiobarbiturates | 1993 |
Intracellular myoglobin loading worsens H2O2-induced, but not hypoxia/reoxygenation-induced, in vitro proximal tubular injury.
Topics: Acute Kidney Injury; Animals; Hydrogen Peroxide; Hydroxybenzoates; Hydroxyl Radical; Hypoxia; In Vitro Techniques; Iron; Kidney Tubules, Proximal; L-Lactate Dehydrogenase; Male; Myoglobin; Rats; Rats, Sprague-Dawley; Salicylates | 1993 |
Brain temperature alters hydroxyl radical production during cerebral ischemia/reperfusion in rats.
Topics: Analysis of Variance; Animals; Body Temperature; Brain; Cerebral Cortex; Cerebrovascular Circulation; Chromatography, High Pressure Liquid; Free Radical Scavengers; Hippocampus; Hydroxybenzoates; Hydroxyl Radical; Hydroxylation; Iron Chelating Agents; Ischemic Attack, Transient; Laser-Doppler Flowmetry; Male; Microdialysis; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Salicylates; Salicylic Acid | 1996 |
Detection of salicylate and its hydroxylated adducts 2,3- and 2,5-dihydroxybenzoic acids as possible indices for in vivo hydroxyl radical formation in combination with catechol- and indoleamines and their metabolites in cerebrospinal fluid and brain tissu
Topics: Animals; Biogenic Amines; Catechols; Chromatography, High Pressure Liquid; Electrochemistry; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Indoles; Magnesium; Male; Manganese Poisoning; Neostriatum; Rats; Rats, Wistar; Reference Standards; Salicylates; Salicylic Acid; Spectrophotometry, Ultraviolet | 1995 |
Detection of hydroxyl radicals in rat striatum during transient focal cerebral ischemia: possible implication in tissue damage.
Topics: Analysis of Variance; Animals; Cerebral Infarction; Corpus Striatum; Disease Models, Animal; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Ischemic Attack, Transient; Male; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 1995 |
Phenytoin-initiated hydroxyl radical formation: characterization by enhanced salicylate hydroxylation.
Topics: Animals; Biotransformation; Female; Gentisates; Glucuronidase; Hydrolysis; Hydroxybenzoates; Hydroxyl Radical; Hydroxylation; Mice; Paraquat; Phenytoin; Salicylates; Salicylic Acid; Teratogens | 1996 |
Mitochondrial generation of reactive oxygen species after brain ischemia in the rat.
Topics: Animals; Blood Pressure; Brain; Carbon Dioxide; Electron Transport; Haloperidol; Hippocampus; Hydroxybenzoates; Hydroxyl Radical; Hydroxylation; Ischemic Attack, Transient; Kinetics; Male; Microdialysis; Mitochondria; NAD(P)H Dehydrogenase (Quinone); Oxygen; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Reperfusion; Rotenone; Succinates; Thiobarbituric Acid Reactive Substances; Time Factors | 1996 |
Antioxidant activity of allicin, an active principle in garlic.
Topics: Animals; Antioxidants; Chromatography, High Pressure Liquid; Disulfides; Free Radical Scavengers; Garlic; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Lipid Peroxidation; Liver; Malondialdehyde; Plants, Medicinal; Rabbits; Reactive Oxygen Species; Salicylates; Salicylic Acid; Sulfinic Acids; Tablets | 1995 |
[Hydroxyl radical generation and post-ischemic reperfusion brain damage implications for neuroprotection].
Topics: Animals; Benzhydryl Compounds; Brain Ischemia; Cell Survival; Cerebral Cortex; Free Radical Scavengers; Gerbillinae; Hippocampus; Hydroxybenzoates; Hydroxyl Radical; Male; Neurons; Reperfusion Injury; Salicylates; Salicylic Acid | 1996 |
Evaluation of hydroxyl radical-scavenging property of garlic.
Topics: Animals; Chromatography, High Pressure Liquid; Free Radical Scavengers; Garlic; Gentisates; Hot Temperature; Hydroxybenzoates; Hydroxyl Radical; Lipid Peroxidation; Liver; Malondialdehyde; Photolysis; Plant Extracts; Plants, Medicinal; Rabbits; Salicylates; Salicylic Acid; Sensitivity and Specificity; Superoxides; Ultraviolet Rays | 1996 |
In vivo monitoring of .OH generation on jejunal ischemic injury by dialysis technique.
Topics: Animals; Hydroxybenzoates; Hydroxyl Radical; Ischemia; Jejunum; Microdialysis; Rats; Rats, Wistar; Reperfusion | 1996 |
Production of hydroxyl radical in the hippocampus after CO hypoxia or hypoxic hypoxia in the rat.
Topics: Animals; Carbon Monoxide Poisoning; Cerebrovascular Circulation; Hemoglobins; Hippocampus; Hydroxybenzoates; Hydroxyl Radical; Hydroxylation; Hypoxia; Male; Oxidative Stress; Oxygen Consumption; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Salicylates; Salicylic Acid | 1997 |
Evidence for increased oxidative stress in alcohol-dependent patients provided by quantification of in vivo salicylate hydroxylation products.
Topics: Adult; Alcoholism; Aspirin; Biotransformation; Female; Humans; Hydroxybenzoates; Hydroxyl Radical; Lipid Peroxidation; Male; Metabolic Clearance Rate; Middle Aged; Oxidative Stress; Reactive Oxygen Species | 1997 |
Halothane prevents postischemic production of hydroxyl radicals in the canine heart.
Topics: Anesthetics, Inhalation; Animals; Dogs; Gentisates; Halothane; Hydroxybenzoates; Hydroxyl Radical; Myocardial Ischemia; Myocardium | 1997 |
Hydroxyl radical-scavenging property of secoisolariciresinol diglucoside (SDG) isolated from flax-seed.
Topics: Butylene Glycols; Chromatography, High Pressure Liquid; Free Radical Scavengers; Gentisates; Glucosides; Hydroxybenzoates; Hydroxyl Radical; Lipid Peroxidation; Seeds; Sensitivity and Specificity; Ultraviolet Rays | 1997 |
Hydroxyl radical production in the brain after CO hypoxia in rats.
Topics: Animals; Brain; Carbon Monoxide Poisoning; Cytosol; Hydroxybenzoates; Hydroxyl Radical; Hydroxylation; Hyperbaric Oxygenation; Hypoxia, Brain; Male; Mitochondria; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Salicylates; Salicylic Acid | 1995 |
Hydroxyl radical generation in beta-thalassemic red blood cells.
Topics: beta-Thalassemia; Catechols; Erythrocytes; Gentisates; Humans; Hydroxybenzoates; Hydroxyl Radical; In Vitro Techniques; Iron; Oxidation-Reduction; Salicylates; Salicylic Acid | 1995 |
Improved method for the estimation of hydroxyl free radical levels in vivo based on liquid chromatography with electrochemical detection.
Topics: Animals; Benzoates; Cerebral Cortex; Chromatography, High Pressure Liquid; Corpus Striatum; Dizocilpine Maleate; Drug Stability; Excitatory Amino Acid Antagonists; Free Radicals; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Hydroxylation; Kidney; Liver; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Salicylates; Sensitivity and Specificity | 1997 |
Protective effect of diltiazem on myocardial ischemic injury associated with .OH generation.
Topics: Allopurinol; Animals; Calcium Channel Blockers; Diltiazem; Heart Rate; Hydroxybenzoates; Hydroxyl Radical; Male; Myocardial Reperfusion Injury; Norepinephrine; Rats; Rats, Wistar; Salicylates; Salicylic Acid; Xanthine; Xanthine Oxidase; Xanthines | 1997 |
Comparative study of .OH generation in brain, heart and liver using microdialysis.
Topics: Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Liver; Male; Microdialysis; Myocardium; Rats; Rats, Wistar; Salicylates | 1997 |
Cardiac microdialysis of salicylic acid .OH generation on nonenzymatic oxidation by norepinephrine in rat heart.
Topics: Animals; Dose-Response Relationship, Drug; Gentisates; Hydroxybenzoates; Hydroxyl Radical; In Vitro Techniques; Male; Microdialysis; Monoamine Oxidase Inhibitors; Myocardium; Norepinephrine; Pargyline; Rats; Rats, Wistar; Salicylates; Salicylic Acid | 1997 |
Use of microdialysis for in-vivo monitoring of hydroxyl free-radical generation in the rat.
Topics: Animals; Brain; Chromatography, High Pressure Liquid; Electric Stimulation; Gentisates; Hydrogen Peroxide; Hydroxybenzoates; Hydroxyl Radical; Iron; Ischemia; Jejunum; Liver; Male; Microdialysis; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Myocardium; Norepinephrine; Pargyline; Rats; Rats, Wistar; Reperfusion Injury; Salicylates; Superoxides; Sympathetic Nervous System | 1997 |
Delayed neuronal death prevented by inhibition of increased hydroxyl radical formation in a transient cerebral ischemia.
Topics: Animals; Antipyrine; Brain Ischemia; Cell Death; Edaravone; Free Radical Scavengers; Hippocampus; Hydroxybenzoates; Hydroxyl Radical; Iron Chelating Agents; Male; Microdialysis; Neurons; Rats; Rats, Wistar; Reperfusion Injury | 1997 |
Hydroxyl radical formation in hyperglycemic rats during middle cerebral artery occlusion/reperfusion.
Topics: Animals; Arterial Occlusive Diseases; Cerebral Arteries; Cerebral Infarction; Enzyme Inhibitors; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Hyperglycemia; In Vitro Techniques; Magnetic Resonance Imaging; Male; Microdialysis; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 1997 |
Evidence of hydroxyl free radical generation by calcium overload in rat myocardium.
Topics: Animals; Calcium; Cardiotonic Agents; Dose-Response Relationship, Drug; Gentisates; Heart; Heart Ventricles; Hydroxybenzoates; Hydroxyl Radical; Hydroxylation; Male; Microdialysis; Mixed Function Oxygenases; Myocardium; Ouabain; Rats; Rats, Wistar; Salicylates; Salicylic Acid | 1997 |
Amphetamine induces hydroxyl radical formation in the striatum of rats.
Topics: alpha-Methyltyrosine; Amphetamine; Animals; Central Nervous System Stimulants; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Electrochemistry; Enzyme Inhibitors; Hydroxybenzoates; Hydroxyl Radical; Hydroxylation; Male; Microinjections; Nalidixic Acid; Naphthyridines; Rats; Rats, Sprague-Dawley; Salicylates | 1997 |
Effects of alpha-phenyl-tert-butylnitrone and selegiline on hydroxyl free radicals in rat striatum produced by local application of glutamate.
Topics: Administration, Topical; Animals; Corpus Striatum; Cyclic N-Oxides; Free Radical Scavengers; Gentisates; Glutamic Acid; Hydroxybenzoates; Hydroxyl Radical; Male; Microdialysis; Monoamine Oxidase Inhibitors; Nitrogen Oxides; Rats; Rats, Wistar; Selegiline | 1998 |
Inhibitory effect of MCI-186, a free radical scavenger, on cerebral ischemia following rat middle cerebral artery occlusion.
Topics: Animals; Antipyrine; Brain; Brain Ischemia; Cerebral Arteries; Constriction; Edaravone; Free Radical Scavengers; Hydroxybenzoates; Hydroxyl Radical; Male; Rats; Rats, Wistar; Visual Cortex | 1998 |
Glutamate induces hydroxyl radical formation in vivo via activation of nitric oxide synthase in Sprague-Dawley rats.
Topics: Animals; Corpus Striatum; Enzyme Inhibitors; Glutamic Acid; Hydroxybenzoates; Hydroxyl Radical; Male; Microdialysis; Neurotoxins; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Rats, Sprague-Dawley; Salicylates; Salicylic Acid | 1998 |
Evidence for accelerated generation of hydroxyl radicals in experimental obstructive jaundice of rats.
Topics: Animals; Cholestasis, Intrahepatic; Common Bile Duct Diseases; Constriction; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Leukocyte Count; Male; Rats; Rats, Wistar | 1998 |
Talipexole protects dopaminergic neurons from methamphetamine toxicity in C57BL/6N mouse.
Topics: Animals; Azepines; Central Nervous System Stimulants; Chromatography, High Pressure Liquid; Dopamine; Dopamine Agonists; Enzyme Induction; Free Radical Scavengers; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Male; Methamphetamine; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Parkinson Disease, Secondary; Receptors, Dopamine D2; Salicylates; Salicylic Acid; Tyrosine 3-Monooxygenase | 1998 |
Salicylate hydroxylation as an indicator of hydroxyl radical generation in dextran sulfate-induced colitis.
Topics: Animals; Chromatography, High Pressure Liquid; Colitis; Dextran Sulfate; Hydrogen Peroxide; Hydroxybenzoates; Hydroxyl Radical; Hydroxylation; Hypochlorous Acid; Intestinal Mucosa; Kinetics; Male; Methionine; Mice; Mice, Inbred CBA; Peroxidase; Salicylates; Salicylic Acid | 1998 |
Simultaneous measurement of monoamines, their metabolites and 2,3- and 2,5-dihydroxybenzoates by high-performance liquid chromatography with electrochemical detection. Application to rat brain dialysates.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Monoamines; Corpus Striatum; Dopamine; Gentisates; Homovanillic Acid; Hydroxybenzoates; Hydroxyindoleacetic Acid; Hydroxyl Radical; Methoxyhydroxyphenylglycol; Norepinephrine; Oxygen; Rats; Restraint, Physical; Serotonin | 1998 |
Hydroxyl radical production in the substantia nigra after 6-hydroxydopamine and hypoxia-reoxygenation.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Dopamine; Hydroxybenzoates; Hydroxyl Radical; Hydroxylation; Hypoxia, Brain; Male; Neurotoxins; Oxidopamine; Oxygen; Partial Pressure; Rats; Rats, Sprague-Dawley; Salicylic Acid; Substantia Nigra | 1998 |
Effects of endurance physical training on hydroxyl radical generation in rat tissues.
Topics: Animals; Chromatography, High Pressure Liquid; Exercise Test; Glutathione; Glutathione Disulfide; Hydroxybenzoates; Hydroxyl Radical; Male; Physical Conditioning, Animal; Rats; Rats, Wistar; Tissue Distribution | 1998 |
A microdialysis study investigating the mechanisms of hydroxyl radical formation in rat striatum exposed to glutamate.
Topics: 2-Amino-5-phosphonovalerate; Animals; Corpus Striatum; Cyclic N-Oxides; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Free Radical Scavengers; Glutamic Acid; Hydroxybenzoates; Hydroxyl Radical; Iron Chelating Agents; Microdialysis; Neurotoxins; NG-Nitroarginine Methyl Ester; Nitrogen Oxides; Quinacrine; Rats; Rats, Sprague-Dawley | 1998 |
1-Trichloromethyl-1,2,3,4-tetrahydro-beta-carboline increases extracellular serotonin and stimulates hydroxyl radical production in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Aspartic Acid; Carbolines; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Extracellular Space; gamma-Aminobutyric Acid; Glutamic Acid; Homovanillic Acid; Hydroxybenzoates; Hydroxyindoleacetic Acid; Hydroxyl Radical; Male; Microdialysis; Rats; Rats, Wistar; Serotonin | 1998 |
Measurement of hydroxyl radical by salicylate in striatum of intact brain.
Topics: Animals; Chromatography, High Pressure Liquid; Convulsants; Corpus Striatum; Gentisates; Glutarates; Hydroxybenzoates; Hydroxyl Radical; Male; Methylguanidine; Microdialysis; Rats; Rats, Wistar; Salicylates | 1999 |
Estimation of hydroxyl free radical levels in vivo based on liquid chromatography with electrochemical detection.
Topics: Chromatography, Liquid; Electrochemistry; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Models, Chemical; Oxidative Stress; Parabens; Salicylic Acid; Tyrosine | 1999 |
[Oxidative stress and hypercholesterolemia: increase of radical hydroxyl in patients with hypercholesterolemia].
Topics: Adult; Aged; Cholesterol; Chromatography, High Pressure Liquid; Chromatography, Liquid; Data Interpretation, Statistical; Female; Gentisates; Humans; Hydroxybenzoates; Hydroxyl Radical; Hypercholesterolemia; Leukocytes; Male; Middle Aged; Oxidative Stress | 1999 |
LC/MS analysis of hydroxylation products of salicylate as an indicator of in vivo oxidative stress.
Topics: Animals; Biomarkers; Calibration; Chromatography, Liquid; Hydroxybenzoates; Hydroxyl Radical; Hydroxylation; Mass Spectrometry; Models, Chemical; Oxidative Stress; Rats; Salicylic Acid | 1999 |
Reserpine prevents hydroxyl radical formation by MPP+ in rat striatum.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Corpus Striatum; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Hydroxybenzoates; Hydroxyl Radical; Iron Chelating Agents; Male; Parkinson Disease, Secondary; Rats; Rats, Wistar; Reserpine; Salicylic Acid; Sympatholytics | 1999 |
Mazindol attenuates the 3,4-methylenedioxymethamphetamine-induced formation of hydroxyl radicals and long-term depletion of serotonin in the striatum.
Topics: Animals; Corpus Striatum; Hydroxybenzoates; Hydroxyl Radical; Kinetics; Male; Mazindol; Microdialysis; N-Methyl-3,4-methylenedioxyamphetamine; Phenylalanine; Rats; Rats, Sprague-Dawley; Salicylic Acid; Serotonin; Tyrosine | 1999 |
Neuronal nitric oxide synthase inhibition reduces MPP+-evoked hydroxyl radical formation but not dopamine efflux in rat striatum.
Topics: 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hydroxybenzoates; Hydroxyl Radical; In Vitro Techniques; Indazoles; Male; Microdialysis; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Rats; Rats, Wistar | 1999 |
Protective effect of histidine on hydroxyl radical generation induced by potassium-depolarization in rat myocardium.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Histidine; Hydroxybenzoates; Hydroxyl Radical; Male; Microdialysis; Myocardial Reperfusion Injury; Myocardium; Potassium; Potassium Chloride; Rats; Rats, Wistar; Sodium Salicylate | 1999 |
Recurrent glutamate stimulations potentiate the hydroxyl radicals response to glutamate.
Topics: Animals; Corpus Striatum; Glutamic Acid; Hydroxybenzoates; Hydroxyl Radical; Male; Microdialysis; Rats | 1999 |
Prazosin attenuates hydroxyl radical generation in the rat myocardium.
Topics: Adrenergic alpha-Agonists; Animals; Antihypertensive Agents; Hydroxybenzoates; Hydroxyl Radical; Iron; Male; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Norepinephrine; Prazosin; Rats; Rats, Wistar; Salicylic Acid; Tyramine | 1999 |
Hydroxyl radical formation following methamphetamine administration to rats.
Topics: Animals; Body Temperature; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Gentisates; Hippocampus; Hydroxybenzoates; Hydroxyl Radical; Injections, Intraventricular; Male; Methamphetamine; Rats; Rats, Wistar; Salicylates; Serotonin | 1999 |
Production of hydroxyl free radical by brain tissues in hyperglycemic rats subjected to transient forebrain ischemia.
Topics: Animals; Brain; Brain Injuries; Brain Ischemia; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Hyperglycemia; Male; Rats; Rats, Wistar; Reactive Oxygen Species; Reperfusion Injury; Salicylic Acid; Tissue Distribution | 1999 |
Formation of free hydroxyl radicals after pentylenetetrazol-induced seizure and kindling.
Topics: Animals; Brain; Convulsants; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Kindling, Neurologic; Male; Pentylenetetrazole; Rats; Rats, Wistar; Seizures | 1999 |
Involvement of monooxygenases and amine oxidases in hydroxyl radical generation in vivo.
Topics: Animals; Cytochrome P-450 Enzyme System; Hydroxybenzoates; Hydroxyl Radical; Keratolytic Agents; Male; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Rats; Rats, Sprague-Dawley; Salicylic Acid | 1999 |
Measurement of hydroxyl radical in rat blood vessel by microbore liquid chromatography and electrochemical detection: an on-line microdialysis study.
Topics: Animals; Blood Vessels; Chromatography, Liquid; Electrodes; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Indicators and Reagents; Jugular Veins; Male; Microdialysis; Rats; Rats, Sprague-Dawley; Salicylic Acid; Sensitivity and Specificity | 1999 |
Involvement of the serotonin transporter in the formation of hydroxyl radicals induced by 3,4-methylenedioxymethamphetamine.
Topics: Animals; Carrier Proteins; Corpus Striatum; Dextroamphetamine; Dopamine Agents; Fluoxetine; Hydroxybenzoates; Hydroxyl Radical; Male; Membrane Glycoproteins; Membrane Transport Proteins; Microdialysis; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Tissue Proteins; Rats; Rats, Sprague-Dawley; Salicylic Acid; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Agents; Serotonin Plasma Membrane Transport Proteins; Time Factors | 1999 |
Generation of reactive oxygen species by the faecal matrix.
Topics: Ascorbic Acid; Bacteria; Catechols; Chromatography, High Pressure Liquid; Edetic Acid; Feces; Free Radical Scavengers; Gentisates; Humans; Hydroxybenzoates; Hydroxyl Radical; Hypoxanthine; Phytic Acid; Reactive Oxygen Species; Salicylic Acid; Xanthine Oxidase | 2000 |
Hydroxyl radicals detected via brain microdialysis in rats breathing air and during hyperbaric oxygen convulsions.
Topics: Air; Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Corpus Striatum; Electron Spin Resonance Spectroscopy; Epilepsy, Tonic-Clonic; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Hyperbaric Oxygenation; Male; Microdialysis; Rats; Rats, Sprague-Dawley; Salicylates | 1999 |
Effect of hydroxyl radical scavengers in renal cortical cells.
Topics: Animals; Benzoates; Free Radical Scavengers; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Hydroxylation; Kidney Cortex; Rats; Rats, Wistar | 1999 |
In vivo hydroxyl radical generation in the striatum following systemic administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Catalase; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Electrochemistry; Glutathione; Hydroxybenzoates; Hydroxyl Radical; Mice; Mice, Inbred BALB C; Time Factors | 2000 |
L-DOPA does not enhance hydroxyl radical formation in the nigrostriatal dopamine system of rats with a unilateral 6-hydroxydopamine lesion.
Topics: Animals; Cerebellum; Corpus Striatum; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Injections; Levodopa; Male; Mesencephalon; Methamphetamine; Microdialysis; Osmolar Concentration; Oxidopamine; Rats; Rats, Sprague-Dawley; Salicylates; Substantia Nigra | 2000 |
Intra-striatal infusion of D-amphetamine induces hydroxyl radical formation: inhibition by MK-801 pretreatment.
Topics: Animals; Body Temperature; Corpus Striatum; Dextroamphetamine; Dizocilpine Maleate; Dopamine; Dopamine Agents; Excitatory Amino Acid Antagonists; Hydroxybenzoates; Hydroxyl Radical; Male; Microdialysis; Rats; Rats, Sprague-Dawley | 2000 |
Cerebral oligaemia episode triggers free radical formation and late cognitive deficiencies.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Aspartic Acid; Carotid Stenosis; Cognition Disorders; Corpus Striatum; Disease Models, Animal; Dopamine; Escape Reaction; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Homovanillic Acid; Hydroxybenzoates; Hydroxyl Radical; Ischemic Attack, Transient; Learning Disabilities; Male; Maze Learning; Memory Disorders; Microdialysis; Oxidative Stress; Psychomotor Performance; Rats; Rats, Wistar; Reaction Time; Reperfusion Injury; Spatial Behavior; Swimming; Time Factors | 2000 |
Effect of barbiturates on hydroxyl radicals, lipid peroxidation, and hypoxic cell death in human NT2-N neurons.
Topics: Barbiturates; Blood Glucose; Cell Death; Cell Line; Humans; Hydroxybenzoates; Hydroxyl Radical; Hydroxylation; Hypoxanthines; Hypoxia; L-Lactate Dehydrogenase; Lipid Peroxidation; Malondialdehyde; Neurons; Oxygen Consumption; Salicylates | 2000 |
Protective effect of fluvastatin, a new inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase, on MPP(+)-induced hydroxyl radical in the rat striatum.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Copper; Corpus Striatum; Dopamine; Extracellular Space; Fatty Acids, Monounsaturated; Fluvastatin; Free Radical Scavengers; Hydroxybenzoates; Hydroxyl Radical; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Lipoproteins, LDL; Male; Microdialysis; Monoamine Oxidase; Nerve Tissue Proteins; Neuroprotective Agents; Neurotoxins; Oxidation-Reduction; Rats; Rats, Wistar | 2000 |
Hydroxyl radical formation in the perilymph of asphyxic guinea pig.
Topics: Animals; Asphyxia; Chromatography, High Pressure Liquid; Electrochemistry; Gentisates; Guinea Pigs; Hydroxybenzoates; Hydroxyl Radical; Perilymph; Salicylates | 2000 |
Evidence for production of hydroxyl radicals by pentachlorophenol metabolites and hydrogen peroxide: A metal-independent organic Fenton reaction.
Topics: Chelating Agents; Hydrogen Peroxide; Hydroquinones; Hydroxybenzoates; Hydroxyl Radical; Iron; Kinetics; Pentachlorophenol; Resorcinols | 2000 |
The salicylate hydroxylation assay to measure hydroxyl free radicals induced by local application of glutamate in vivo or induced by the Fenton reaction in vitro.
Topics: Animals; Dose-Response Relationship, Drug; Gentisates; Glutamic Acid; Hydroxybenzoates; Hydroxyl Radical; Hydroxylation; Male; Methods; Microdialysis; Rats; Rats, Wistar; Salicylates | 2000 |
Neuroprotection by sodium salicylate against 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine-induced neurotoxicity.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Catalepsy; Cyclooxygenase Inhibitors; Dopamine; Dopamine Agents; Dyskinesia, Drug-Induced; Female; Free Radical Scavengers; Gentisates; Glutathione; Homovanillic Acid; Hydroxybenzoates; Hydroxyl Radical; Male; Mice; Mice, Inbred BALB C; Monoamine Oxidase; MPTP Poisoning; Neostriatum; Neuroprotective Agents; Sodium Salicylate; Substantia Nigra | 2000 |
Fluvastatin, a new inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase, resists hydroxyl radical generation in the rat myocardium.
Topics: Animals; Copper; Dose-Response Relationship, Drug; Fatty Acids, Monounsaturated; Female; Fluvastatin; Heart; Hydroxybenzoates; Hydroxyl Radical; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Male; Microdialysis; Myocardium; Rats; Rats, Wistar; Time Factors; Tyramine | 2000 |
Lead promotes hydroxyl radical generation and lipid peroxidation in cultured aortic endothelial cells.
Topics: Animals; Aorta, Thoracic; Cell Count; Cell Survival; Cells, Cultured; Culture Media; Endothelium, Vascular; Hydroxybenzoates; Hydroxyl Radical; Hypertension; Lead; Lipid Peroxidation; Malondialdehyde; Rats; Rats, Sprague-Dawley; Thiobarbiturates | 2000 |
Block of cardiac ATP-sensitive K(+) channels reduces hydroxyl radicals in the rat myocardium.
Topics: Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Antihypertensive Agents; Cromakalim; Decanoic Acids; Dose-Response Relationship, Drug; Ferrous Compounds; Glyburide; Hydroxy Acids; Hydroxybenzoates; Hydroxyl Radical; Hypoglycemic Agents; Inhibitory Concentration 50; Iron Chelating Agents; Male; Microdialysis; Myocardial Ischemia; Myocardium; Nicorandil; Potassium Channel Blockers; Rats; Rats, Wistar; Salicylates; Time Factors | 2000 |
Reperfusion injury pathophysiology in sickle transgenic mice.
Topics: Allopurinol; Anemia, Sickle Cell; Animals; Biomarkers; Enzyme Inhibitors; Ethane; Hemoglobin, Sickle; Humans; Hydroxybenzoates; Hydroxyl Radical; Kidney; Lipid Peroxidation; Liver; Mice; Mice, Inbred C57BL; Mice, Transgenic; NF-kappa B; Reference Values; Reperfusion Injury; Salicylic Acid; Xanthine Dehydrogenase; Xanthine Oxidase | 2000 |
Comparative effects of melatonin, L-deprenyl, Trolox and ascorbate in the suppression of hydroxyl radical formation during dopamine autoxidation in vitro.
Topics: Antioxidants; Ascorbic Acid; Chromans; Dopamine; Dose-Response Relationship, Drug; Hydroxybenzoates; Hydroxyl Radical; Iron; Melatonin; Oxidation-Reduction; Salicylates; Selegiline | 2000 |
N-methyl-D-aspartate but not glutamate induces the release of hydroxyl radicals in the neonatal rat: modulation by group I metabotropic glutamate receptors.
Topics: Animals; Animals, Newborn; Corpus Striatum; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Hydroxybenzoates; Hydroxyl Radical; Hypoxia-Ischemia, Brain; Ibotenic Acid; Indans; Microdialysis; N-Methylaspartate; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Resorcinols | 2000 |
Dopaminergic denervation enhances susceptibility to hydroxyl radicals in rat neostriatum.
Topics: Animals; Carbidopa; Chromatography, High Pressure Liquid; Denervation; Dihydroxyphenylalanine; Dopamine; Female; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Neostriatum; Pregnancy; Rats; Salicylic Acid; Serotonin | 2000 |
The dopamine agonist pramipexole scavenges hydroxyl free radicals induced by striatal application of 6-hydroxydopamine in rats: an in vivo microdialysis study.
Topics: Adrenergic Agents; Animals; Benzothiazoles; Corpus Striatum; Dopamine; Dopamine Agonists; Hydroxybenzoates; Hydroxyl Radical; Male; Microdialysis; Oxidopamine; Pergolide; Pramipexole; Rats; Rats, Wistar; Thiazoles | 2000 |
Determination of salicylate hydroxylation products as an in vivo oxidative stress marker.
Topics: Adult; Aspirin; Biomarkers; Chromatography, High Pressure Liquid; Humans; Hydroxybenzoates; Hydroxyl Radical; Hydroxylation; Oxidative Stress; Salicylic Acid; Sensitivity and Specificity | 2000 |
Hyperbaric oxygen reduces cerebral blood flow by inactivating nitric oxide.
Topics: Animals; Blood Flow Velocity; Blood Gas Analysis; Blood Pressure; Cerebrovascular Circulation; Corpus Striatum; Electroencephalography; Enzyme Inhibitors; Hydrazines; Hydroxybenzoates; Hydroxyl Radical; Hyperbaric Oxygenation; Injections, Intravenous; Microdialysis; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitrites; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2000 |
In vivo evidence for accelerated generation of hydroxyl radicals in liver of Long-Evans Cinnamon (LEC) rats with acute hepatitis.
Topics: Acute Disease; Animals; Copper; Copper Sulfate; Female; Free Radical Scavengers; Hepatitis, Animal; Hydroxybenzoates; Hydroxyl Radical; Liver; Mannitol; Rats; Rats, Inbred LEC; Rats, Wistar; Salicylic Acid | 2001 |
Systemic administration of d-amphetamine induces long-lasting oxidative stress in the rat striatum.
Topics: Animals; Antidepressive Agents, Tricyclic; Biomarkers; Central Nervous System Stimulants; Desipramine; Dextroamphetamine; Dizocilpine Maleate; Hydroxybenzoates; Hydroxyl Radical; Lipid Peroxidation; Male; Malondialdehyde; Neostriatum; Neuroprotective Agents; Oxidative Stress; Rats; Rats, Sprague-Dawley | 2000 |
Potent, hydroxyl radical-scavenging effect of apomorphine with iron and dopamine perfusion in rat striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Corpus Striatum; Dopamine; Dopamine Agonists; Free Radical Scavengers; Hydroxybenzoates; Hydroxyl Radical; Iron; Male; Microdialysis; Rats; Rats, Sprague-Dawley | 2001 |
6-hydroxydopamine increases hydroxyl free radical production and DNA damage in rat striatum.
Topics: Adrenergic Agents; Animals; Corpus Striatum; Cytosine; DNA Damage; Gas Chromatography-Mass Spectrometry; Hydroxybenzoates; Hydroxyl Radical; Hypoxanthine; Male; Oxidopamine; Rats; Rats, Wistar | 2001 |
Nitric oxide enhances MPP(+)-induced hydroxyl radical generation via depolarization activated nitric oxide synthase in rat striatum.
Topics: 1-Methyl-4-phenylpyridinium; Allopurinol; Animals; Dopamine; Enzyme Inhibitors; Extracellular Space; Herbicides; Hydroxybenzoates; Hydroxyl Radical; Iron; Iron Chelating Agents; Male; Membrane Potentials; Microdialysis; Neostriatum; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress; Parkinson Disease; Potassium; Rats; Rats, Wistar | 2001 |
Increased hydroxyl radicals in the hippocampus of stroke-prone spontaneously hypertensive rats during transient ischemia and recirculation.
Topics: Animals; Hippocampus; Hydroxybenzoates; Hydroxyl Radical; Hypertension; Ischemic Attack, Transient; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reperfusion Injury; Stroke | 2001 |
Release of dopamine by perfusion with 1-methyl-4-phenylpyridinium ion (MPP(+)) into the striatum is associated with hydroxyl free radical generation.
Topics: 1-Methyl-4-phenylpyridinium; Adrenergic Uptake Inhibitors; Animals; Antifungal Agents; Cell Membrane; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Extracellular Space; Herbicides; Hydroxybenzoates; Hydroxyl Radical; Lipid Peroxidation; Male; Neostriatum; Nerve Degeneration; Neural Pathways; Neurons; Oxidative Stress; Rats; Rats, Wistar; Reserpine; Salicylic Acid; Substantia Nigra | 2001 |
In vivo hydroxyl radical formation after quinolinic acid infusion into rat corpus striatum.
Topics: Animals; Chromatography, High Pressure Liquid; Corpus Striatum; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutathione; Glutathione Peroxidase; Hydroxybenzoates; Hydroxyl Radical; Lipid Peroxidation; Male; Microdialysis; Microinjections; Neuroprotective Agents; Nitro Compounds; Oxidative Stress; Perfusion; Propionates; Quinolinic Acid; Rats; Rats, Wistar; Salicylic Acid; Wakefulness | 2001 |
Formation of hydroxyl radicals during myocardial reperfusion after experimental ischemia of different duration.
Topics: Animals; Hydroxybenzoates; Hydroxyl Radical; Male; Microdialysis; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Reperfusion Injury; Rats; Rats, Wistar | 2001 |
Citrulline, a novel compatible solute in drought-tolerant wild watermelon leaves, is an efficient hydroxyl radical scavenger.
Topics: Citrulline; Citrullus; DNA; DNA Damage; Free Radical Scavengers; Hydroxybenzoates; Hydroxyl Radical; Hydroxylation; Kinetics; L-Lactate Dehydrogenase; Malate Dehydrogenase; Oxidation-Reduction; Plant Leaves; Pyruvate Kinase; Reactive Oxygen Species; Salicylates; Water | 2001 |
Protective effect of histidine on para-nonylphenol-enhanced hydroxyl free radical generation induced by 1-methyl-4-phenylpyridinium ion (MPP+) in rat striatum.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Corpus Striatum; Dopamine; Free Radicals; Histidine; Hydroxybenzoates; Hydroxyl Radical; Male; Microdialysis; Phenols; Rats; Rats, Wistar; Reserpine | 2001 |
Iron (III) attenuates hydroxyl radical generation accompanying non-enzymatic oxidation of noradrenaline in the rat heart.
Topics: Animals; Female; Ferric Compounds; Hydroxybenzoates; Hydroxyl Radical; Intracellular Fluid; Male; Microdialysis; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Norepinephrine; Oxidation-Reduction; Rats; Rats, Wistar; Sodium Salicylate; Tyramine | 2002 |
Mechanisms for the induction of oxidative stress in Syrian hamster embryo cells by acrylonitrile.
Topics: Acrylonitrile; Animals; Carcinogens; Catalase; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Dose-Response Relationship, Drug; Drug Synergism; Embryo, Mammalian; Glutathione; Hydroxybenzoates; Hydroxyl Radical; Mesocricetus; Oxidative Stress; Reactive Oxygen Species; Superoxide Dismutase; Time Factors; Triazoles; Xanthine Oxidase | 2002 |
Endogenous released ascorbic acid suppresses ethanol-induced hydroxyl radical production in rat striatum.
Topics: Alcohol-Induced Disorders, Nervous System; Animals; Ascorbic Acid; Drug Interactions; Ethanol; Extracellular Space; Female; Fenfluramine; Hydroxybenzoates; Hydroxyl Radical; Male; Microdialysis; Neostriatum; Nerve Degeneration; Neurons; Oxidative Stress; Rats; Selective Serotonin Reuptake Inhibitors; Sex Characteristics | 2002 |
Effect of imipramine on 1-methyl-4-phenylpyridinium ion-induced hydroxyl radical generation in rat striatum.
Topics: Animals; Antidepressive Agents, Tricyclic; Corpus Striatum; Dopamine; Female; Hydroxybenzoates; Hydroxyl Radical; Imipramine; Lactams; Microdialysis; Monoamine Oxidase; Pyridones; Rats; Rats, Wistar | 2002 |
Ischemia and reperfusion of skeletal muscle lead to the appearance of a stable lipid free radical in the circulation.
Topics: Animals; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Female; Free Radicals; Hindlimb; Hydroxybenzoates; Hydroxyl Radical; Lipids; Microdialysis; Muscle Contraction; Muscle, Skeletal; Nitrogen Oxides; Oxidants; Prostaglandins; Rats; Rats, Wistar; Reperfusion Injury; Superoxides | 2003 |
Estimation of hydroxyl radicals based on the salicylate trapping method in hippocampus of stroke-prone spontaneously hypertensive rats (SHRSP) during transient ischemia and recirculation.
Topics: Animals; Cerebrovascular Circulation; Hippocampus; Hydroxybenzoates; Hydroxyl Radical; Ischemic Attack, Transient; Microcirculation; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 2003 |
Non-steroidal anti-inflammatory drug sodium salicylate, but not diclofenac or celecoxib, protects against 1-methyl-4-phenyl pyridinium-induced dopaminergic neurotoxicity in rats.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Corpus Striatum; Diclofenac; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Gentisates; Hydroxybenzoates; Hydroxyl Radical; In Vitro Techniques; Male; Mortality; Neurodegenerative Diseases; Neuroprotective Agents; Pyrazoles; Rats; Rats, Inbred Strains; Rats, Sprague-Dawley; Sodium Salicylate; Sulfonamides | 2003 |
Postischemic hypothermia inhibits the generation of hydroxyl radical following transient forebrain ischemia in rats.
Topics: Animals; Brain; Brain Chemistry; Cerebrovascular Circulation; Corpus Striatum; Extracellular Space; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Hypothermia, Induced; Ischemic Attack, Transient; Male; Microdialysis; Rats; Rats, Wistar; Xanthine | 2003 |
Effects of iNOS-related NO on hearts exposed to liposoluble iron.
Topics: Animals; Arginine; Heart; Heart Ventricles; Hydroxybenzoates; Hydroxyl Radical; Immunoblotting; Iron; Lipopolysaccharides; Myocardial Contraction; Myocardium; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Nitroarginine; Oxidative Stress; Perfusion; Rats; Rats, Wistar; Reperfusion Injury; Salicylic Acid; Time Factors | 2003 |
Phospholipase A2, hydroxyl radicals, and lipid peroxidation in transient cerebral ischemia.
Topics: Animals; Arachidonic Acid; Calcium; Cardiolipins; Cell Membrane; Chromatography, High Pressure Liquid; Cytidine Diphosphate Choline; Gentisates; Gerbillinae; Hippocampus; Hydroxybenzoates; Hydroxyl Radical; Intracellular Membranes; Ischemic Attack, Transient; Lipid Peroxidation; Male; Malondialdehyde; Mitochondria; Models, Biological; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipases A; Phospholipases A2; Salicylic Acid | 2003 |
Selective brain hypothermia protects against hypoxic-ischemic injury in newborn rats by reducing hydroxyl radical production.
Topics: Animals; Animals, Newborn; Brain; Cell Count; Cell Survival; Cerebrovascular Circulation; Disease Models, Animal; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Hypothermia, Induced; Hypoxia-Ischemia, Brain; Neurons; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 2003 |
Inhibitory effect of free radical scavenger, MCI-186, in the increase of hydroxyl radical induced by iminodipropionitrile in rats.
Topics: Animals; Antipyrine; Brain; Edaravone; Free Radical Scavengers; Hydroxybenzoates; Hydroxyl Radical; Male; Movement Disorders; Nitriles; Rats; Rats, Wistar | 2004 |
Role of reactive oxygen species in the sensitivity of rat hypertrophied myocardium to ischemia.
Topics: Animals; Cardiac Output; Cardiomegaly; Catechols; Chromatography, High Pressure Liquid; Hydroxybenzoates; Hydroxyl Radical; Male; Microdialysis; Myocardial Ischemia; Myocardial Reperfusion Injury; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Species Specificity | 2004 |
Characterization of hydroxyl radical generation in the striatum of free-moving rats due to carbon monoxide poisoning, as determined by in vivo microdialysis.
Topics: Animals; Carbon Monoxide Poisoning; Corpus Striatum; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Hydroxybenzoates; Hydroxyl Radical; Male; Microdialysis; Quinoxalines; Rats; Rats, Sprague-Dawley; Tetrodotoxin; Wakefulness | 2004 |
Diabetes-induced changes in glucose synthesis, intracellular glutathione status and hydroxyl free radical generation in rabbit kidney-cortex tubules.
Topics: Animals; Catechols; Diabetes Mellitus, Experimental; Gluconeogenesis; Glucose; Glucose-6-Phosphate; Glutathione; Hydroxybenzoates; Hydroxyl Radical; Kidney Tubules; Malates; Male; Mitochondria; Oxidation-Reduction; Pyruvic Acid; Rabbits | 2004 |
Ischaemic preconditioning but not isoflurane prevents post-ischaemic production of hydroxyl radicals in a canine model of ischaemia-reperfusion.
Topics: Anesthetics, Inhalation; Animals; Antidotes; Blood Pressure; Catechols; Deferoxamine; Dogs; Heart Rate; Hydrogen-Ion Concentration; Hydroxybenzoates; Hydroxyl Radical; Ischemic Preconditioning, Myocardial; Isoflurane; Lactic Acid; Myocardial Reperfusion Injury; Myocardium; Oxygen Consumption; Salicylates | 2005 |
Isoflurane does not mimic ischaemic preconditioning in decreasing hydroxyl radical production in the rabbit.
Topics: Anesthetics, Inhalation; Animals; Gentisates; Hemodynamics; Hydroxybenzoates; Hydroxyl Radical; Ischemic Preconditioning, Myocardial; Isoflurane; Myocardial Infarction; Rabbits | 2005 |
Effects of alpha-phenyl-N-tert-butyl nitrone and N-acetylcysteine on hydroxyl radical formation and dopamine depletion in the rat striatum produced by d-amphetamine.
Topics: Acetylcysteine; Animals; Body Temperature; Cyclic N-Oxides; Dextroamphetamine; Dopamine; Dopamine Uptake Inhibitors; Free Radical Scavengers; Hydroxybenzoates; Hydroxyl Radical; Lipid Peroxidation; Male; Microdialysis; Neostriatum; Neuroprotective Agents; Neurotoxicity Syndromes; Nitrogen Oxides; Pilot Projects; Rats; Rats, Sprague-Dawley | 2006 |
Production of reactive oxygen species following acute ethanol or acetaldehyde and its reduction by acamprosate in chronically alcoholized rats.
Topics: Acamprosate; Acetaldehyde; Alcohol Deterrents; Alcoholism; Animals; Disease Models, Animal; Ethanol; Gentisates; Hippocampus; Hydroxybenzoates; Hydroxyl Radical; Male; Microdialysis; Rats; Rats, Wistar; Salicylic Acid; Substance Withdrawal Syndrome; Taurine; Time Factors | 2005 |
An NMDA receptor-dependent hydroxyl radical pathway in the rabbit hypothalamus may mediate lipopolysaccharide fever.
Topics: Acetylcysteine; Analgesics, Non-Narcotic; Animals; Antioxidants; Body Temperature; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Fever; Hydroxybenzoates; Hydroxyl Radical; Isoquinolines; Lipopolysaccharides; Male; Rabbits; Receptors, N-Methyl-D-Aspartate; Thioctic Acid | 2006 |
Activation of protein kinase C enhances 1-methyl-4-phenylpyridinium ion (MPP+)-induced hydroxylradical generation in rat striatum.
Topics: 1-Methyl-4-phenylpyridinium; Alkaloids; Animals; Benzophenanthridines; Catechols; Cations, Monovalent; Corpus Striatum; Enzyme Activation; Hydroxybenzoates; Hydroxyl Radical; Male; Phenanthridines; Protein Kinase C; Rats; Rats, Wistar | 2006 |
The production of hydroxyl radicals in the fetal lamb brain resulting from occlusion of the umbilical circulation and the transplacental effect of MCI-186 to inhibit hydroxyl radical production.
Topics: Animals; Antipyrine; Brain; Catechols; Edaravone; Female; Free Radical Scavengers; Hydroxybenzoates; Hydroxyl Radical; Maternal-Fetal Exchange; Pregnancy; Regional Blood Flow; Sheep; Umbilical Cord | 2006 |
Protective effect of fluvastatin, an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase, on copper-induced hydroxyl radical generation in the rat heart.
Topics: Animals; Cardiotonic Agents; Copper; Dose-Response Relationship, Drug; Extracellular Fluid; Fatty Acids, Monounsaturated; Fluvastatin; Hydroxybenzoates; Hydroxyl Radical; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Male; Microdialysis; Myocardium; Rats; Rats, Wistar | 2006 |
Effect of MK-801 and ketamine on hydroxyl radical generation in the posterior cingulate and retrosplenial cortex of free-moving mice, as determined by in vivo microdialysis.
Topics: Animals; Behavior, Animal; Catechols; Cerebral Cortex; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Extracellular Space; Gyrus Cinguli; Hydroxybenzoates; Hydroxyl Radical; Ketamine; Male; Mice; Microdialysis; Stereotyped Behavior | 2007 |
Blocking cardiac ATP-sensitive K+ channels reduces hydroxyl radicals caused by potassium chloride-induced depolarization in the rat myocardium.
Topics: Adenosine Triphosphate; Animals; Decanoic Acids; Glyburide; Hydroxy Acids; Hydroxybenzoates; Hydroxyl Radical; Kinetics; Male; Membrane Potentials; Myocardial Reperfusion Injury; Myocardium; Potassium Channels; Potassium Chloride; Rats; Rats, Wistar | 2006 |
Estimation of hydroxyl radical generation by salicylate hydroxylation method in multiple organs of mice exposed to whole-body X-ray irradiation.
Topics: Animals; Catechols; Dose-Response Relationship, Radiation; Hydroxybenzoates; Hydroxyl Radical; Hydroxylation; Male; Mice; Mice, Inbred ICR; Radiation Injuries, Experimental; Salicylates; Tissue Distribution; Whole-Body Irradiation; X-Rays | 2006 |
Nicorandil improves post-ischemic myocardial dysfunction in association with opening the mitochondrial K(ATP) channels and decreasing hydroxyl radicals in isolated rat hearts.
Topics: Animals; Heart Ventricles; Hydroxybenzoates; Hydroxyl Radical; In Vitro Techniques; Male; Myocardial Ischemia; Myocardium; Nicorandil; Potassium Channels; Rats; Rats, Sprague-Dawley; Vasodilator Agents | 2006 |
Lipopolysaccharide- and glutamate-induced hypothalamic hydroxyl radical elevation and fever can be suppressed by N-methyl-D-aspartate-receptor antagonists.
Topics: Animals; Dinoprostone; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Fever; Glutamic Acid; Hydroxybenzoates; Hydroxyl Radical; Hypothalamus; Injections, Intraventricular; Isoquinolines; Lipopolysaccharides; Male; Rabbits; Random Allocation; Receptors, N-Methyl-D-Aspartate | 2007 |
Ischemic preconditioning in the rat hippocampus increases antioxidant activities but does not affect the level of hydroxyl radicals during subsequent severe ischemia.
Topics: Animals; Antioxidants; Catalase; Enzyme Activation; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Hippocampus; Hydrogen Peroxide; Hydroxybenzoates; Hydroxyl Radical; Ischemic Attack, Transient; Ischemic Preconditioning; Male; Prosencephalon; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 2007 |
Sonocatalytic facilitation of hydroxyl radical generation in the presence of TiO2.
Topics: Aluminum Oxide; Catechols; Chromatography, High Pressure Liquid; Electrochemistry; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Gases; Hydroxybenzoates; Hydroxyl Radical; Salicylates; Spin Trapping; Titanium; Ultrasonics; X-Ray Diffraction | 2008 |
Protective effect of captopril and enalaprilat, angiotensin-converting enzyme inhibitors, on para-nonylphenol-induced *OH generation and dopamine efflux in rat striatum.
Topics: 1-Methyl-4-phenylpyridinium; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Catechols; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Enalaprilat; Hydroxybenzoates; Hydroxyl Radical; Iron; Male; Neostriatum; Phenols; Rats; Rats, Wistar | 2008 |
The protective effect of fluvastatin on hydroxyl radical generation by inhibiting low-density lipoprotein (LDL) oxidation in the rat myocardium.
Topics: Animals; Antioxidants; Atherosclerosis; Catechols; Copper; Fatty Acids, Monounsaturated; Fluvastatin; Heart; Hydroxybenzoates; Hydroxyl Radical; Indoles; Lipoproteins, LDL; Male; Microdialysis; Myocardium; Oxidation-Reduction; Rats; Rats, Wistar | 2009 |
Hydroxyl radical generation dependent on extracellular ascorbate in rat striatum, as determined by microdialysis.
Topics: Animals; Ascorbic Acid; Behavior, Animal; Corpus Striatum; Dehydroascorbic Acid; Extracellular Space; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Male; Microdialysis; Rats; Rats, Sprague-Dawley | 2009 |
Acarbose reduces myocardial infarct size by preventing postprandial hyperglycemia and hydroxyl radical production and opening mitochondrial KATP channels in rabbits.
Topics: Acarbose; Animals; Blood Glucose; Catechols; Enzyme Inhibitors; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Hyperglycemia; Male; Myocardial Infarction; Potassium Channels; Rabbits | 2009 |
Hydroxyl radical is produced via the Fenton reaction in submitochondrial particles under oxidative stress: implications for diseases associated with iron accumulation.
Topics: Animals; Catechols; Cattle; Chromatography, High Pressure Liquid; Hydroxybenzoates; Hydroxyl Radical; Mitochondria, Heart; Oxidative Stress; Reactive Oxygen Species; Submitochondrial Particles | 2009 |
Involvement of extracellular ascorbate and iron in hydroxyl radical generation in rat striatum in carbon monoxide poisoning.
Topics: Ammonia; Animals; Antioxidants; Ascorbate Oxidase; Ascorbic Acid; Brain Chemistry; Carbon Monoxide Poisoning; Catechols; Hydroxybenzoates; Hydroxyl Radical; Iron; Iron Chelating Agents; Male; Microdialysis; Neostriatum; Rats; Rats, Sprague-Dawley; Stereotaxic Techniques | 2009 |
Hyperbaric oxygenation alleviates MCAO-induced brain injury and reduces hydroxyl radical formation and glutamate release.
Topics: Animals; Blood Pressure; Brain; Brain Injuries; Gentisates; Glutamates; Hydroxybenzoates; Hydroxyl Radical; Hyperbaric Oxygenation; Infarction, Middle Cerebral Artery; Male; Models, Animal; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 2010 |
Central interleukin-10 attenuated lipopolysaccharide-induced changes in core temperature and hypothalamic glutamate, hydroxyl radicals and prostaglandin-E(2).
Topics: Animals; Body Temperature; Catechols; Dinoprostone; Fever; Glutamic Acid; Hydroxybenzoates; Hydroxyl Radical; Hypothalamus; Interleukin-10; Lipopolysaccharides; Male; Microdialysis; Rabbits; Tumor Necrosis Factor-alpha | 2011 |
Dual contradictory roles of cAMP signaling pathways in hydroxyl radical production in the rat striatum.
Topics: Adenylyl Cyclases; Animals; Biomimetic Materials; Carbon Monoxide; Carbon Monoxide Poisoning; Colforsin; Corpus Striatum; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Guanine Nucleotide Exchange Factors; Hydroxybenzoates; Hydroxyl Radical; Isoquinolines; Male; Models, Animal; Rats; Rats, Sprague-Dawley; Signal Transduction; Sulfonamides | 2012 |
Opening of ATP-sensitive K(+) (KATP) channels enhance hydroxyl radical generation induced by MPP(+) in rat striatum.
Topics: Animals; Corpus Striatum; Cromakalim; Dopamine; Dose-Response Relationship, Drug; Glyburide; Hydroxybenzoates; Hydroxyl Radical; KATP Channels; Male; Membrane Transport Modulators; Microdialysis; MPTP Poisoning; Nicorandil; Rats, Wistar | 2016 |