2,3-bis(3'-hydroxybenzyl)butyrolactone and phytoestrogens

2,3-bis(3'-hydroxybenzyl)butyrolactone has been researched along with phytoestrogens in 93 studies

Compound Research Comparison

Studies (2,3-bis(3'-hydroxybenzyl)butyrolactone)	Trials (2,3-bis(3'-hydroxybenzyl)butyrolactone)	Recent Studies (post-2010) (2,3-bis(3'-hydroxybenzyl)butyrolactone)	Studies (phytoestrogens)	Trials (phytoestrogens)	Recent Studies (post-2010) (phytoestrogens)
319	32	124	3,794	258	1,520

Research

Studies (93)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (1.08)	18.7374
1990's	8 (8.60)	18.2507
2000's	43 (46.24)	29.6817
2010's	35 (37.63)	24.3611
2020's	6 (6.45)	2.80

Authors

Authors	Studies
Adlercreutz, H; Benassayag, C; Garreau, B; Mäkelä, T; Nunez, EA; Vallette, G; Wähälä, K	1
Adlercreutz, H; Bannwart, C; Brunow, G; Fotsis, T; Hase, T; Mäkelä, T; Musey, PI; Wähälä, K	1
Hutchins, AM; Lampe, JW; Slavin, JL	1
Joannou, GE; Kelly, GE; Nelson, C; Reeder, AY; Waring, MA	1
Benassayag, C; Haourigui, M; Martin, ME; Nunez, EA; Pelissero, C	1
Ingram, D; Kolybaba, M; Lopez, D; Sanders, K	1
Kurzer, MS; Wang, C	1
Brüggemann-Rotgans, IE; Kardinaal, AF; Morton, MS; van Beresteijn, EC	1
Adlercreutz, H; Al-Maharik, N; Hampl, R; Lapcík, O; Mäkelä, T; Mikola, H; Uehara, M; Wähälä, K	1
Adlercreutz, H; Arai, Y; Uehar, M; Watanabe, S	1
Adlercreut, H; Hallmans, G; Hultén, K; Kilkkinen, A; Mazur, W; Pietinen, P; Stumpf, K	1
Adlercreutz, H; Arts, CJ; den Tonkelaar, I; Keinan-Boker, L; Peeters, PH; Thijssen, JH; Veer, PV	1
Ayton, R; Dalais, FS; Grehan, M; Medley, G; Murkies, AL; Rice, GE; Strauss, BJ; Wahlqvist, ML	1
Chung, BC; Huh, KB; Kim, MK; Lee, HC; Lim, SK; Nam, JH; Yu, VY	1
Collan, YU; Eckerman, C; Huovinen, R; Mäkelä, SI; Needham, L; Saarinen, NM; Santti, R; Valentín-Blasini, L; Wärri, A	1
Adlercreutz, H	2
Arisaka, O; Evans, BA; Miyake, N; Morgan, LD; Morton, MS	1
Ammälä, J; Collan, YU; Eckerman, C; Huovinen, R; Lehtilä, R; Mäkelä, SI; Saarinen, NM; Santti, RS; Sjöholm, R; Valentín-Blasini, L; Wärri, A	1
Grobbee, DE; Keinan-Boker, L; Peeters, PH; van der Schouw, YT	1
Bingham, SA; Botting, NP; Fryatt, T; Grace, PB; Oldfield, MF; Taylor, JI	1
Andre, F; Antignac, JP; Cariou, R; Cravedi, JP; Le Bizec, B	1
Adlercreutz, H; Begum, AN; Fukushima, K; Heinonen, SM; Lapierre, C; Mila, I; Nagano, K; Nicolle, C; Rémésy, C; Scalbert, A	1
Chung, BC; Jung, BH; Kim, SY; Lee, SH	1
Adlercreutz, H; Auprich, M; Brössner, C; Fink, K; Madersbacher, S; Petritsch, K; Petritsch, P; Rehak, P	1
Liu, Z; Moline, J; Wolff, MS	1
Adlercreutz, H; Biessy, C; Bylund, A; Hallmans, G; Kaaks, R; Stattin, P	1
Brooks, JD; Thompson, LU	1
Engel, SM; Kaplan, D; Levy, B; Liu, Z; Wolff, MS	1
Coulman, KD; Hum, WQ; Liu, Z; Michaelides, J; Thompson, LU	1
Alpert, CA; Blaut, M; Clavel, T; Doré, J; Henderson, G; Philippe, C; Rigottier-Gois, L	1
Bingham, SA; Day, NE; Doody, D; Dowsett, M; Dunning, AM; Folkerd, E; Grace, PB; Khaw, KT; Low, YL; Luben, RN; Mulligan, AA; Scollen, S; Taylor, JI; Wareham, NJ; Welch, AA	1
Adami, HO; Adlercreutz, H; Andersson, SO; Bälter, KA; Bellocco, R; Chang, ET; Grönberg, H; Hedelin, M; Heinonen, SM; Johansson, JE; Klint, A	1
Chen, JM; Power, KA; Saarinen, NM; Thompson, LU; Ward, WE	1
Chang-Claude, J; Linseisen, J; Piller, R	1
Blaut, M; Clavel, T; Doré, J; Gavini, F; Lippman, R	1
Bergman Jungeström, M; Dabrosin, C; Thompson, LU	1
Biro, F; Britton, JA; Calafat, AM; Chelimo, C; Godbold, J; Kushi, LH; Pfeiffer, CM; Pinney, SM; Teitelbaum, SL; Windham, G; Wolff, MS	1
Alexander, FE; Bolton-Smith, C; Heald, CL; Morton, MS; Ritchie, MR	1
Arts, IC; Feskens, EJ; Hollman, PC; Kampman, E; Kuijsten, A; Milder, IE; Van 't Veer, P	1
Adlercreutz, H; Ericson, U; Gullberg, B; Peñalvo, JL; Sonestedt, E; Wirfält, E	1
Bombelli, R; Cosentino, M; Crema, F; Delle Canne, MG; Ferrari, M; Lecchini, S; Legnaro, M; Luini, A; Luzzani, M; Marino, F; Paracchini, S; Rasini, E	1
Chen, LH; Demark-Wahnefried, W; Fang, J; Li, H; Lin, X	1
Antignac, JP; Dip, R; Gmuender, H; Le Bizec, B; Lenz, S; Naegeli, H	1
Berrar, D; Gill, CI; Linton, T; McCann, MJ; McGlynn, H; Rowland, IR	1
Bennetau-Pelissero, C; Carreau, C; Flouriot, G; Potier, M	1
Bruun, JM; Bügel, S; Hallund, J; Tetens, I; Tholstrup, T	1
Airio, M; Dings, RP; Mäkelä, S; Saarinen, NM; Smeds, AI; Wärri, A	1
Karkola, S; Wähälä, K	1
Adlercreutz, H; Carlson, J; Ericson, U; Gullberg, B; Harlid, S; Ivarsson, MI; Olsson, H; Sonestedt, E; Wirfält, E	1
Bergeron, J; John Weisnagel, S; Lemieux, S; Morisset, AS; Tchernof, A; Veilleux, A	1
Kang, J; Price, WE	1
Bach Knudsen, KE; Christensen, J; Egeberg, R; Johnsen, NF; Loft, S; Olsen, A; Overvad, K; Thomsen, BL; Tjønneland, A	1
Nijmeijer, SM; Ruchirawat, S; van den Berg, M; van Duursen, MB	1
Balsari, A; Morelli, D; Palazzo, M; Rossini, A; Rumio, C; Sfondrini, L; Tagliabue, E; Zanobbio, L	1
Albini, A; Bachmeier, BE; Blengio, F; Dell'eva, R; Esposito, A; Generoso, L; Killian, PH; Mirisola, V; Pfeffer, U; Romeo, F	1
Eiler, H; Fecteau, KA; Oliver, JW	1
Damdimopoulos, AE; Damdimopoulou, P; Kotka, M; Mäkelä, S; Nurmi, T; Pongratz, I; Poutanen, M; Salminen, A; Strauss, L; van der Saag, P	1
Abarzua, S; Briese, V; Piechulla, B; Richter, DU; Serikawa, T; Szewczyk, M	1
Buck, K; Chang-Claude, J; Flesch-Janys, D; Heinz, J; Linseisen, J; Vrieling, A; Zaineddin, AK	1
Adlercreutz, H; Håkansson, N; Lagergren, J; Lin, Y; Lu, Y; Peñalvo, JL; Wolk, A	1
Chang, SH; Cho, LY; Choi, BY; Han, DS; Kang, D; Kim, YS; Ko, KP; Ma, SH; Park, SK; Shin, A; Shin, HR; Song, KS; Yang, JJ; Yoo, KY	1
Aarestrup, J; Christensen, J; Johnsen, NF; Knudsen, KE; Kristensen, M; Kyrø, C; Olsen, A; Overvad, K; Tjønneland, A; Weiderpass, E; Würtz, AM	1
Martinchik, AN; Zubtsov, VV	1
Pfeiffer, CM; Rybak, ME; Sternberg, MR	1
Biro, FM; Galvez, MP; Gardiner, EW; Kushi, LH; Mervish, NA; Pinney, SM; Rybak, ME; Teitelbaum, SL; Windham, GC; Wolff, MS	1
Barr, DB; Louis, GM; Maisog, JM; Mumford, SL; Parker, DL; Pfeiffer, CM; Rybak, ME; Schisterman, EF; Sundaram, R; Sweeney, AM	1
Frankenfeld, CL	1
Chang, SH; Cho, LY; Choi, BY; Han, DS; Kang, D; Kim, HJ; Kim, YS; Ko, KP; Ma, SH; Park, SK; Shin, A; Shin, HR; Song, KS; Yang, JJ; Yoo, KY	1
Gu, A; Jiang, ZY; Liu, Q; Xu, C; Zhang, Q	2
Alcorn, J; Krol, ES; Muir, AD; Mukker, JK; Singh, RS	1
Jones, J; Liu, Z; Reger, MK; Zhang, J; Zollinger, TW	1
Boyd Barr, D; Buck Louis, GM; Chen, Z; Kim, S; Mumford, SL	1
Hori, S; Nakagawa, H; Sugahara, T; Tamura, M; Yamauchi, S	1
Duan, Z; Li, K; Liu, Z; Wang, L; Wu, Y; Zhang, M	1
Abarzua, S; Chrobak, M; Jeschke, U; Kuhn, C; Piechulla, B; Richter, DU; Schröder, L; Schulze, S; Weissenbacher, T	1
Brecchia, G; Cartoni Mancinelli, A; Castellini, C; Dal Bosco, A; Mattioli, S; Ruggeri, S; Sebastiani, B	1
Bach Knudsen, KE; Bolvig, AK; Foldager, L; Hedemann, MS; Lærke, HN; Marco, ML; McCarthy-Sinclair, B; Nørskov, NP	1
Gaya, P; Landete, JM; Medina, M; Peirotén, Á; Sánchez-Jiménez, A	1
Chang-Claude, J; Herpel, E; Jaskulski, S; Johnson, T; Jung, AY; Rudolph, A; Sinn, P; Thöne, K	1
Bao, HX; Gao, S; Gao, T; Hu, S; Johnston, RN; Li, QH; Li, T; Liu, H; Liu, J; Liu, SL; Liu, Y; Mastriani, E; Qi, Y; Shen, Z; Wang, H; Wang, S; Wang, X; Yu, M; Zeng, Z; Zhou, YJ	1
Chang, SH; Kang, CH; Kang, D; Kim, CS; Ko, KP; Koriyama, C; Lim, YK; Ngoan, LT; Park, SK; Shin, HR; Tokudome, S; Yeo, Y; Yoo, KY; Yoon, JH	1
Djukovic, D; Gu, H; Hullar, MAJ; Kratz, M; Lampe, JW; Lampe, PD; Miles, FL; Navarro, SL; Neuhouser, ML; Raftery, D; Randolph, TW; Schwarz, Y; Shojaie, A	1
Bach Knudsen, KE; Eriksen, AK; Frederiksen, K; Hansen, L; Holm, M; Kyrø, C; Nørskov, NP; Olsen, A; Tjønneland, A	1
Berk, K; Chabowski, A; Charytoniuk, T; Drygalski, K; Iłowska, N; Konstantynowicz-Nowicka, K	1
Hayworth, JS; Liu, L; Mulabagal, V; Qi, J; Wilson, C	1
Becher, H; Behrens, S; Chang-Claude, J; Gonzalez-Maldonado, S; Hell, R; Huebner, M; Hüsing, A; Jaskulski, S; Jung, AY; Obi, N; Poschet, G	1
Brzostek, T; Del Rio, D; Favari, C; Galvano, F; Gniadek, A; Godos, J; Grosso, G; Libra, M; Mena, P; Micek, A	1
Dong, X; Jiang, H; Sun, J; Wang, W; Zhang, D	1
Kang, JY; Ko, KP; Lee, J; Park, SK	1
Bennetau-Pelissero, C; Bensaada, S; Pellegrin, I; Raymond, I; Viallard, JF	1
Chen, Y; Yang, F	1

Reviews

7 review(s) available for 2,3-bis(3'-hydroxybenzyl)butyrolactone and phytoestrogens

Article	Year
Food containing phytoestrogens, and breast cancer. BioFactors (Oxford, England), 2000, Volume: 12, Issue:1-4 Topics: 4-Butyrolactone; Animals; Breast Neoplasms; Edible Grain; Estrogens; Estrogens, Non-Steroidal; Female; Finland; Food; Humans; Isoflavones; Japan; Lignans; Phytoestrogens; Plant Preparations; Pregnancy; Prenatal Exposure Delayed Effects	2000
Phyto-oestrogens and cancer. The Lancet. Oncology, 2002, Volume: 3, Issue:6 Topics: 4-Butyrolactone; Animals; Breast Neoplasms; Diet; Estrogens, Non-Steroidal; Female; Glycine max; Humans; Isoflavones; Lignans; Male; Neoplasms; Phytoestrogens; Plant Preparations; Prostatic Neoplasms; Tumor Cells, Cultured	2002
Phytoestrogens and breast cancer risk. Review of the epidemiological evidence. Breast cancer research and treatment, 2003, Volume: 77, Issue:2 Topics: 4-Butyrolactone; Adolescent; Adult; Age Factors; Breast Neoplasms; Case-Control Studies; Climacteric; Diet; Estrogens; Estrogens, Non-Steroidal; Female; Glycine max; Humans; Isoflavones; Lignans; Male; Phytoestrogens; Plant Preparations; Plants; Prospective Studies; Risk	2003
Lignans and human health. Critical reviews in clinical laboratory sciences, 2007, Volume: 44, Issue:5-6 Topics: 4-Butyrolactone; Animals; Cardiovascular Diseases; Colorectal Neoplasms; Dietary Fiber; Edible Grain; Endometrial Neoplasms; Feeding Behavior; Female; Health Status; Humans; Isoflavones; Lignans; Male; Phytoestrogens; Plants, Edible; Prostatic Neoplasms; Seeds; Vegetables	2007
[Phytoestrogenis properties of flaxseed lignans]. Voprosy pitaniia, 2012, Volume: 81, Issue:6 Topics: 4-Butyrolactone; Animals; Antioxidants; Flax; Humans; Lignans; Neoplasms, Experimental; Phytoestrogens	2012
Gene polymorphisms in the ornithine decarboxylase-polyamine pathway modify gastric cancer risk by interaction with isoflavone concentrations. Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 2015, Volume: 18, Issue:3 Topics: 4-Butyrolactone; Adenosylmethionine Decarboxylase; Asian People; Case-Control Studies; Equol; Gene-Environment Interaction; Genistein; Humans; Isoflavones; Lignans; Multicenter Studies as Topic; NAD(P)H Dehydrogenase (Quinone); Nitric Oxide Synthase Type II; Ornithine Decarboxylase; Phytoestrogens; Polyamines; Polymorphism, Single Nucleotide; Stomach Neoplasms	2015
Dietary phytoestrogens and biomarkers of their intake in relation to cancer survival and recurrence: a comprehensive systematic review with meta-analysis. Nutrition reviews, 2021, 01-01, Volume: 79, Issue:1 Topics: 4-Butyrolactone; Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Diet; Eating; Female; Humans; Isoflavones; Lignans; Male; Middle Aged; Neoplasms; Phytoestrogens; Young Adult	2021

Trials

5 trial(s) available for 2,3-bis(3'-hydroxybenzyl)butyrolactone and phytoestrogens

Article	Year
Urinary isoflavonoid phytoestrogen and lignan excretion after consumption of fermented and unfermented soy products. Journal of the American Dietetic Association, 1995, Volume: 95, Issue:5 Topics: 4-Butyrolactone; Adult; Chromans; Cross-Over Studies; Defecation; Diet; Equol; Estrogens; Estrogens, Non-Steroidal; Fermentation; Food Handling; Genistein; Glycine max; Humans; Isoflavones; Lignans; Male; Phytoestrogens; Plant Preparations; Taste	1995
Effects of dietary phytoestrogens in postmenopausal women. Climacteric : the journal of the International Menopause Society, 1998, Volume: 1, Issue:2 Topics: 4-Butyrolactone; Aged; Bone Density; Diet; Double-Blind Method; Estrogens, Non-Steroidal; Female; Genistein; Glycine max; Hot Flashes; Humans; Isoflavones; Lignans; Linseed Oil; Middle Aged; Phytoestrogens; Plant Preparations; Postmenopause; Triticum	1998
Whole sesame seed is as rich a source of mammalian lignan precursors as whole flaxseed. Nutrition and cancer, 2005, Volume: 52, Issue:2 Topics: 4-Butyrolactone; Administration, Oral; Aged; Cross-Over Studies; Female; Flax; Humans; Lignans; Phytoestrogens; Postmenopause; Seeds; Sesamum	2005
The effect of a lignan complex isolated from flaxseed on inflammation markers in healthy postmenopausal women. Nutrition, metabolism, and cardiovascular diseases : NMCD, 2008, Volume: 18, Issue:7 Topics: 4-Butyrolactone; Biomarkers; C-Reactive Protein; Cross-Over Studies; Double-Blind Method; Female; Flax; Humans; Inflammation; Lignans; Middle Aged; Phytoestrogens; Postmenopause; Time Factors	2008
Plasma metabolite abundances are associated with urinary enterolactone excretion in healthy participants on controlled diets. Food & function, 2017, Sep-20, Volume: 8, Issue:9 Topics: 4-Butyrolactone; Adult; Cross-Over Studies; Cross-Sectional Studies; Dietary Fiber; Female; Healthy Volunteers; Humans; Lignans; Male; Middle Aged; Phytoestrogens; Plant Extracts	2017

Other Studies

81 other study(ies) available for 2,3-bis(3'-hydroxybenzyl)butyrolactone and phytoestrogens

Article	Year
Phytoestrogens: new ligands for rat and human alpha-fetoprotein. Biochimica et biophysica acta, 1991, Sep-24, Volume: 1094, Issue:3 Topics: 4-Butyrolactone; Adult; alpha-Fetoproteins; Animals; Arachidonic Acid; Binding, Competitive; Butylene Glycols; Chromans; Equol; Estrogens; Estrogens, Non-Steroidal; Humans; Immunoelectrophoresis; Isoflavones; Ligands; Lignans; Masoprocol; Phytoestrogens; Plant Preparations; Rats; Rats, Inbred Strains	1991
Identification of lignans and phytoestrogens in urine of chimpanzees. Clinica chimica acta; international journal of clinical chemistry, 1986, Jul-30, Volume: 158, Issue:2 Topics: 4-Butyrolactone; Animals; Butylene Glycols; Chromans; Diet; Equol; Estrogens; Estrogens, Non-Steroidal; Isoflavones; Lignans; Male; Pan troglodytes; Phytoestrogens; Plant Extracts; Plant Preparations	1986
The variable metabolic response to dietary isoflavones in humans. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1995, Volume: 208, Issue:1 Topics: 4-Butyrolactone; Adult; Chromans; Diet; Equol; Estrogens, Non-Steroidal; Female; Glycine max; Humans; Isoflavones; Lignans; Male; Middle Aged; Phytoestrogens; Plant Preparations	1995
Interactions between phytoestrogens and human sex steroid binding protein. Life sciences, 1996, Volume: 58, Issue:5 Topics: 4-Butyrolactone; Electrophoresis, Polyacrylamide Gel; Estradiol; Estrogens, Non-Steroidal; Genistein; Humans; Immunoelectrophoresis, Two-Dimensional; Isoflavones; Kinetics; Lignans; Masoprocol; Phytoestrogens; Plant Preparations; Plants; Sex Hormone-Binding Globulin; Structure-Activity Relationship; Testosterone	1996
Case-control study of phyto-oestrogens and breast cancer. Lancet (London, England), 1997, Oct-04, Volume: 350, Issue:9083 Topics: 4-Butyrolactone; Breast Neoplasms; Case-Control Studies; Chromans; Diet; Equol; Estrogens, Non-Steroidal; Female; Humans; Isoflavones; Lignans; Middle Aged; Phytoestrogens; Plant Preparations; Plants; Risk Factors	1997
Effects of phytoestrogens on DNA synthesis in MCF-7 cells in the presence of estradiol or growth factors. Nutrition and cancer, 1998, Volume: 31, Issue:2 Topics: 4-Butyrolactone; Anticarcinogenic Agents; Antineoplastic Agents, Hormonal; Breast Neoplasms; Chamomile; Coumestrol; DNA, Neoplasm; Epidermal Growth Factor; Estradiol; Estrogens, Non-Steroidal; Female; Flavonoids; Genistein; Humans; Insulin; Isoflavones; Lignans; Luteolin; Oils, Volatile; Phytoestrogens; Plant Preparations; Plants, Medicinal; Tamoxifen; Tumor Cells, Cultured	1998
Phyto-oestrogen excretion and rate of bone loss in postmenopausal women. European journal of clinical nutrition, 1998, Volume: 52, Issue:11 Topics: 4-Butyrolactone; Aging; Bone Density; Chromans; Equol; Estrogens, Non-Steroidal; Female; Gas Chromatography-Mass Spectrometry; Genistein; Humans; Isoflavones; Lignans; Linear Models; Middle Aged; Osteoporosis, Postmenopausal; Phytoestrogens; Plant Preparations; Postmenopause; Prospective Studies; Time Factors	1998
Rapid analysis of phytoestrogens in human urine by time-resolved fluoroimmunoassay. The Journal of steroid biochemistry and molecular biology, 2000, Volume: 72, Issue:5 Topics: 4-Butyrolactone; Animals; Cross Reactions; Estrogens, Non-Steroidal; Evaluation Studies as Topic; Female; Fluoroimmunoassay; Gas Chromatography-Mass Spectrometry; Genistein; Humans; Isoflavones; Lignans; Phytoestrogens; Plant Preparations; Rabbits; Sensitivity and Specificity; Serum Albumin, Bovine	2000
Comparison of plasma and urinary phytoestrogens in Japanese and Finnish women by time-resolved fluoroimmunoassay. BioFactors (Oxford, England), 2000, Volume: 12, Issue:1-4 Topics: 4-Butyrolactone; Adult; Aged; Diet; Estrogens, Non-Steroidal; Europium; Female; Finland; Fluoroimmunoassay; Gas Chromatography-Mass Spectrometry; Genistein; Humans; Isoflavones; Japan; Lignans; Middle Aged; Phytoestrogens; Plant Preparations; Reference Values; Sensitivity and Specificity	2000
Urinary phytoestrogens and postmenopausal breast cancer risk. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2001, Volume: 10, Issue:3 Topics: 4-Butyrolactone; Aged; Biomarkers, Tumor; Breast Neoplasms; Case-Control Studies; Cohort Studies; Confidence Intervals; Estrogens, Non-Steroidal; Female; Fluoroimmunoassay; Genetic Predisposition to Disease; Genistein; Humans; Isoflavones; Lignans; Logistic Models; Mass Screening; Middle Aged; Netherlands; Odds Ratio; Phytoestrogens; Plant Preparations; Postmenopause; Predictive Value of Tests; Reference Values; Risk Assessment; Risk Factors; Sensitivity and Specificity	2001
Relationships of urinary phyto-oestrogen excretion to BMD in postmenopausal women. Clinical endocrinology, 2002, Volume: 56, Issue:3 Topics: 4-Butyrolactone; Aged; Aging; Apigenin; Body Mass Index; Bone Density; Estrogens, Non-Steroidal; Female; Femur Neck; Flavonoids; Gas Chromatography-Mass Spectrometry; Humans; Isoflavones; Lignans; Lumbar Vertebrae; Middle Aged; Phytoestrogens; Plant Preparations; Postmenopause; Regression Analysis	2002
Uptake and metabolism of hydroxymatairesinol in relation to its anticarcinogenicity in DMBA-induced rat mammary carcinoma model. Nutrition and cancer, 2001, Volume: 41, Issue:1-2 Topics: 4-Butyrolactone; 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Anticarcinogenic Agents; Diet; Estrogens, Non-Steroidal; Female; Isoflavones; Lignans; Mammary Neoplasms, Experimental; Organ Size; Phytoestrogens; Plant Preparations; Rats; Rats, Sprague-Dawley; Uterus	2001
Phytoestrogen concentrations in serum from Japanese men and women over forty years of age. The Journal of nutrition, 2002, Volume: 132, Issue:10 Topics: 4-Butyrolactone; Adult; Aged; Aged, 80 and over; Breast Neoplasms; Chromans; Diet; Equol; Estrogens, Non-Steroidal; Female; Gas Chromatography-Mass Spectrometry; Genistein; Humans; Isoflavones; Japan; Lignans; Male; Middle Aged; Phytoestrogens; Plant Preparations; Prostatic Neoplasms; United Kingdom	2002
Enterolactone inhibits the growth of 7,12-dimethylbenz(a)anthracene-induced mammary carcinomas in the rat. Molecular cancer therapeutics, 2002, Volume: 1, Issue:10 Topics: 4-Butyrolactone; 9,10-Dimethyl-1,2-benzanthracene; Animals; Aromatase Inhibitors; Carcinogens; Cell Division; Enzyme Inhibitors; Estrogens; Estrogens, Non-Steroidal; Female; Isoflavones; Lignans; Mammary Neoplasms, Animal; Models, Chemical; Organ Size; Phytoestrogens; Plant Preparations; Rats; Rats, Sprague-Dawley; Time Factors; Uterus	2002
Quantification of isoflavones and lignans in urine using gas chromatography/mass spectrometry. Analytical biochemistry, 2003, Apr-01, Volume: 315, Issue:1 Topics: 4-Butyrolactone; Equol; Female; Gas Chromatography-Mass Spectrometry; Genistein; Humans; Isoflavones; Lignans; Molecular Structure; Phytoestrogens; Plant Preparations; Reproducibility of Results; Sensitivity and Specificity	2003
Identification of phytoestrogens in bovine milk using liquid chromatography/electrospray tandem mass spectrometry. Rapid communications in mass spectrometry : RCM, 2003, Volume: 17, Issue:12 Topics: 4-Butyrolactone; Animals; Cattle; Chromans; Chromatography, Liquid; Coumestrol; Equol; Estrogens, Non-Steroidal; Genistein; Ions; Isoflavones; Lignans; Milk; Molecular Structure; Phytoestrogens; Plant Preparations; Spectrometry, Mass, Electrospray Ionization	2003
Dietary lignins are precursors of mammalian lignans in rats. The Journal of nutrition, 2004, Volume: 134, Issue:1 Topics: 4-Butyrolactone; Animals; Biological Availability; Cell Wall; Cellulases; Chromatography, Liquid; Deuterium; Diet; Gas Chromatography-Mass Spectrometry; Glycoside Hydrolases; Isoflavones; Lignans; Lignin; Male; Phytoestrogens; Plant Preparations; Rats; Rats, Wistar; Secale; Spectrometry, Mass, Electrospray Ionization; Triticum	2004
Determination of phytoestrogens in traditional medicinal herbs using gas chromatography--mass spectrometry. The Journal of nutritional biochemistry, 2004, Volume: 15, Issue:8 Topics: 4-Butyrolactone; Chemistry Techniques, Analytical; Fabaceae; Flavonoids; Gas Chromatography-Mass Spectrometry; Lignans; Phytoestrogens; Plants, Medicinal; Reproducibility of Results; Sensitivity and Specificity	2004
Phytoestrogen tissue levels in benign prostatic hyperplasia and prostate cancer and their association with prostatic diseases. Urology, 2004, Volume: 64, Issue:4 Topics: 4-Butyrolactone; Adenocarcinoma; Aged; Aged, 80 and over; Diet; Genistein; Humans; Lignans; Male; Middle Aged; Organ Size; Phytoestrogens; Prostate; Prostatic Hyperplasia; Prostatic Neoplasms	2004
Analysis of environmental biomarkers in urine using an electrochemical detector. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2005, May-05, Volume: 819, Issue:1 Topics: 4-Butyrolactone; Benzhydryl Compounds; Biomarkers; Child; Chromatography, High Pressure Liquid; Electrochemistry; Environmental Exposure; Female; Genistein; Humans; Isoflavones; Lignans; Middle Aged; Phenols; Phytoestrogens	2005
Prospective study of plasma enterolactone and prostate cancer risk (Sweden). Cancer causes & control : CCC, 2004, Volume: 15, Issue:10 Topics: 4-Butyrolactone; Cohort Studies; Humans; Life Style; Lignans; Male; Middle Aged; Obesity; Phytoestrogens; Prospective Studies; Prostatic Neoplasms; Risk; Smoking; Sweden	2004
Mammalian lignans and genistein decrease the activities of aromatase and 17beta-hydroxysteroid dehydrogenase in MCF-7 cells. The Journal of steroid biochemistry and molecular biology, 2005, Volume: 94, Issue:5 Topics: 17-Hydroxysteroid Dehydrogenases; 4-Butyrolactone; Animals; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Cell Line, Tumor; Estradiol; Female; Genistein; Humans; Lignans; Mammals; Phytoestrogens	2005
Xenobiotic phenols in early pregnancy amniotic fluid. Reproductive toxicology (Elmsford, N.Y.), 2006, Volume: 21, Issue:1 Topics: 4-Butyrolactone; Amniotic Fluid; Benzhydryl Compounds; Estrogens, Non-Steroidal; Female; Genistein; Humans; Isoflavones; Lignans; Maternal Exposure; Maternal-Fetal Exchange; Phenols; Phytoestrogens; Pregnancy; Xenobiotics	2006
Intestinal bacterial communities that produce active estrogen-like compounds enterodiol and enterolactone in humans. Applied and environmental microbiology, 2005, Volume: 71, Issue:10 Topics: 4-Butyrolactone; Actinobacteria; Adult; Bacteria, Anaerobic; Butylene Glycols; Colony Count, Microbial; Culture Media; Female; Flow Cytometry; Glucosides; Humans; In Situ Hybridization, Fluorescence; Intestines; Lignans; Male; Middle Aged; Peptostreptococcus; Phytoestrogens	2005
Polymorphisms in the CYP19 gene may affect the positive correlations between serum and urine phytoestrogen metabolites and plasma androgen concentrations in men. The Journal of nutrition, 2005, Volume: 135, Issue:11 Topics: 4-Butyrolactone; Aged; Androgens; Androstane-3,17-diol; Aromatase; Diet; Equol; Genistein; Genotype; Humans; Isoflavones; Lignans; Male; Middle Aged; Phytoestrogens; Polymorphism, Genetic; Sex Hormone-Binding Globulin; Testosterone	2005
Dietary phytoestrogen, serum enterolactone and risk of prostate cancer: the cancer prostate Sweden study (Sweden). Cancer causes & control : CCC, 2006, Volume: 17, Issue:2 Topics: 4-Butyrolactone; Diet; Health Behavior; Humans; Life Style; Lignans; Male; Phytoestrogens; Prostatic Neoplasms; Risk Factors; Sweden	2006
Genistein alone and in combination with the mammalian lignans enterolactone and enterodiol induce estrogenic effects on bone and uterus in a postmenopausal breast cancer mouse model. Bone, 2006, Volume: 39, Issue:1 Topics: 4-Butyrolactone; Animals; Antineoplastic Agents; Bone and Bones; Bone Density; Drug Combinations; Estrogens; Female; Genistein; Humans; Lignans; Mammary Neoplasms, Animal; Mice; Mice, Inbred BALB C; Mice, Nude; Organ Size; Ovariectomy; Phytoestrogens; Postmenopause; Uterus; Xenograft Model Antitumor Assays	2006
Plasma enterolactone and genistein and the risk of premenopausal breast cancer. European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP), 2006, Volume: 15, Issue:3 Topics: 4-Butyrolactone; Adult; Breast Neoplasms; Case-Control Studies; Diet; Female; Genistein; Humans; Lignans; Middle Aged; Phytoestrogens; Plant Preparations; Premenopause; Risk Factors	2006
Clostridium saccharogumia sp. nov. and Lactonifactor longoviformis gen. nov., sp. nov., two novel human faecal bacteria involved in the conversion of the dietary phytoestrogen secoisolariciresinol diglucoside. Systematic and applied microbiology, 2007, Volume: 30, Issue:1 Topics: 4-Butyrolactone; Adult; Base Composition; Butylene Glycols; Clostridium; Colon; Culture Media; Dietary Carbohydrates; DNA; DNA, Ribosomal; Feces; Genotype; Glucosides; Gram-Positive Rods; Humans; Lignans; Male; Molecular Sequence Data; Nucleic Acid Hybridization; Phenotype; Phylogeny; Phytoestrogens; RNA, Ribosomal, 16S	2007
Flaxseed and its lignans inhibit estradiol-induced growth, angiogenesis, and secretion of vascular endothelial growth factor in human breast cancer xenografts in vivo. Clinical cancer research : an official journal of the American Association for Cancer Research, 2007, Feb-01, Volume: 13, Issue:3 Topics: 4-Butyrolactone; Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Endothelium, Vascular; Estradiol; Female; Flax; Humans; Lignans; Mice; Neoplasm Transplantation; Neovascularization, Pathologic; Phytoestrogens; Umbilical Veins; Vascular Endothelial Growth Factor A	2007
Pilot study of urinary biomarkers of phytoestrogens, phthalates, and phenols in girls. Environmental health perspectives, 2007, Volume: 115, Issue:1 Topics: 4-Butyrolactone; Biomarkers; California; Child; Cities; Creatinine; Environmental Monitoring; Female; Humans; Isoflavones; Lignans; New York; Ohio; Phenols; Phthalic Acids; Phytoestrogens; Pilot Projects	2007
Phyto-oestrogens and risk of prostate cancer in Scottish men. The British journal of nutrition, 2007, Volume: 98, Issue:2 Topics: 4-Butyrolactone; Aged; Case-Control Studies; Diet; Diet Surveys; Energy Intake; Equol; Genistein; Humans; Isoflavones; Lignans; Male; Middle Aged; Phytoestrogens; Prostatic Neoplasms; Risk Assessment; Scotland	2007
Relation between plasma enterodiol and enterolactone and dietary intake of lignans in a Dutch endoscopy-based population. The Journal of nutrition, 2007, Volume: 137, Issue:5 Topics: 4-Butyrolactone; Adenomatous Polyps; Adult; Aged; Case-Control Studies; Colonoscopy; Colorectal Neoplasms; Diet; Female; Humans; Lignans; Male; Middle Aged; Phytoestrogens	2007
Variation in fasting and non-fasting serum enterolactone concentrations in women of the Malmö Diet and Cancer cohort. European journal of clinical nutrition, 2008, Volume: 62, Issue:8 Topics: 4-Butyrolactone; Biomarkers; Cohort Studies; Diet; Fasting; Female; Fluoroimmunoassay; Humans; Lignans; Middle Aged; Phytoestrogens; Postprandial Period; Prospective Studies; Risk Assessment; Risk Factors	2008
Estrogenic activity of 7-hydroxymatairesinol potassium acetate (HMR/lignan) from Norway spruce (Picea abies) knots and of its active metabolite enterolactone in MCF-7 cells. Pharmacological research, 2007, Volume: 56, Issue:2 Topics: 4-Butyrolactone; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Estradiol; Estrogen Antagonists; Female; Gene Expression Regulation, Neoplastic; Humans; Lignans; Phytoestrogens; Picea; Proto-Oncogene Proteins c-bcl-2; RNA, Messenger; Tamoxifen	2007
Enterolactone induces apoptosis in human prostate carcinoma LNCaP cells via a mitochondrial-mediated, caspase-dependent pathway. Molecular cancer therapeutics, 2007, Volume: 6, Issue:9 Topics: 4-Butyrolactone; Apoptosis; Caspases; Cell Survival; Cytochromes c; Enzyme Activation; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Immunoblotting; In Situ Nick-End Labeling; Lignans; Male; Membrane Potential, Mitochondrial; Mitochondria; Phytoestrogens; Poly(ADP-ribose) Polymerases; Prostatic Neoplasms; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-mdm2; Tumor Cells, Cultured; Tumor Suppressor Protein p53	2007
Global gene expression profiles induced by phytoestrogens in human breast cancer cells. Endocrine-related cancer, 2008, Volume: 15, Issue:1 Topics: 4-Butyrolactone; Animals; Biomarkers, Tumor; Breast Neoplasms; Cattle; Estradiol; Estrogen Receptor beta; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genistein; Humans; Isoflavones; Lignans; Milk; Neoplasm Proteins; Oligonucleotide Array Sequence Analysis; Phytoestrogens; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Soy Milk; Tumor Cells, Cultured	2008
Enterolactone restricts the proliferation of the LNCaP human prostate cancer cell line in vitro. Molecular nutrition & food research, 2008, Volume: 52, Issue:5 Topics: 4-Butyrolactone; Cell Division; Cell Line, Tumor; Cell Survival; Humans; Lignans; Male; Mitochondria; Phytoestrogens; Polymerase Chain Reaction; Prostate-Specific Antigen; Prostatic Neoplasms	2008
Enterodiol and enterolactone, two major diet-derived polyphenol metabolites have different impact on ERalpha transcriptional activation in human breast cancer cells. The Journal of steroid biochemistry and molecular biology, 2008, Volume: 110, Issue:1-2 Topics: 4-Butyrolactone; Animals; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; CHO Cells; Cricetinae; Cricetulus; Estrogen Receptor alpha; Flavonoids; HeLa Cells; Humans; Lignans; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Phenols; Phytoestrogens; Polyphenols; Reverse Transcriptase Polymerase Chain Reaction; Transcriptional Activation	2008
Dietary lariciresinol attenuates mammary tumor growth and reduces blood vessel density in human MCF-7 breast cancer xenografts and carcinogen-induced mammary tumors in rats. International journal of cancer, 2008, Sep-01, Volume: 123, Issue:5 Topics: 4-Butyrolactone; 9,10-Dimethyl-1,2-benzanthracene; Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Apoptosis; Butylene Glycols; Carcinogens; Cell Proliferation; Dietary Supplements; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Furans; Gene Expression Regulation, Neoplastic; Humans; Lignans; Mammary Neoplasms, Experimental; Mice; Mice, Nude; Ovariectomy; Phytoestrogens; Rats; Receptors, Progesterone; Transplantation, Heterologous	2008
The binding of lignans, flavonoids and coumestrol to CYP450 aromatase: a molecular modelling study. Molecular and cellular endocrinology, 2009, Mar-25, Volume: 301, Issue:1-2 Topics: 4-Butyrolactone; Androgens; Aromatase; Benzoflavones; Catalytic Domain; Computer Simulation; Coumestrol; Estrone; Heme; Lignans; Models, Molecular; Phytoestrogens	2009
The protective association of high plasma enterolactone with breast cancer is reasonably robust in women with polymorphisms in the estrogen receptor alpha and beta genes. The Journal of nutrition, 2009, Volume: 139, Issue:5 Topics: 4-Butyrolactone; Aged; Breast Neoplasms; Cohort Studies; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Genetic Predisposition to Disease; Humans; Lignans; Middle Aged; Phytoestrogens; Polymorphism, Single Nucleotide; Prospective Studies	2009
Impact of a lignan-rich diet on adiposity and insulin sensitivity in post-menopausal women. The British journal of nutrition, 2009, Volume: 102, Issue:2 Topics: 4-Butyrolactone; Adiposity; Aged; Analysis of Variance; Biomarkers; Body Composition; Body Mass Index; Diet; Diet Records; Female; Fluoroimmunoassay; Humans; Insulin Resistance; Lignans; Middle Aged; Phytoestrogens; Postmenopause; Statistics, Nonparametric	2009
Occurrence of phytoestrogens in municipal wastewater and surface waters. Journal of environmental monitoring : JEM, 2009, Volume: 11, Issue:8 Topics: 4-Butyrolactone; Chromatography, Liquid; Coumestrol; Dairying; Environmental Monitoring; Fresh Water; Isoflavones; Lignans; Phytoestrogens; Spectrometry, Mass, Electrospray Ionization; Waste Disposal, Fluid; Water Pollutants, Chemical	2009
Plasma enterolactone and risk of colon and rectal cancer in a case-cohort study of Danish men and women. Cancer causes & control : CCC, 2010, Volume: 21, Issue:1 Topics: 4-Butyrolactone; Case-Control Studies; Cohort Studies; Colonic Neoplasms; Denmark; Feeding Behavior; Female; Humans; Life Style; Lignans; Male; Middle Aged; Phytoestrogens; Rectal Neoplasms; Risk Factors	2010
Chemopreventive actions by enterolactone and 13 VIOXX-related lactone derivatives in H295R human adrenocortical carcinoma cells. Toxicology letters, 2010, Feb-15, Volume: 192, Issue:3 Topics: 4-Butyrolactone; Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Cell Cycle; Cell Line, Tumor; Enzyme Induction; Flavonoids; Gene Expression; Humans; Lactones; Lignans; Mitogen-Activated Protein Kinase Kinases; Neoplasms, Hormone-Dependent; Phytoestrogens; Protein Processing, Post-Translational; Steroid 17-alpha-Hydroxylase; Structure-Activity Relationship; Sulfones	2010
Influence of lignans depletion on murine mammary gland morphology. Nutrition and cancer, 2010, Volume: 62, Issue:2 Topics: 4-Butyrolactone; Animals; Anti-Bacterial Agents; Apoptosis; Bacteria; Cell Division; Ciprofloxacin; Female; Gentamicins; Intestines; Lignans; Mammary Glands, Animal; Metronidazole; Mice; Morphogenesis; Phytoestrogens	2010
Reference profile correlation reveals estrogen-like trancriptional activity of Curcumin. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2010, Volume: 26, Issue:3 Topics: 4-Butyrolactone; Cell Line, Tumor; Curcumin; Estradiol; Gene Expression Profiling; Humans; Inhibitor of Apoptosis Proteins; Lignans; Microtubule-Associated Proteins; Phytoestrogens; Proto-Oncogene Proteins; Quercetin; Reference Values; Survivin; Trans-Activators; Transcription, Genetic	2010
Effect of combined lignan phytoestrogen and melatonin treatment on secretion of steroid hormones by adrenal carcinoma cells. American journal of veterinary research, 2011, Volume: 72, Issue:5 Topics: 4-Butyrolactone; Adrenal Glands; Animals; Aromatase; Cell Line; Cyclic AMP; Dogs; Humans; Lignans; Melatonin; Phytoestrogens; Steroids	2011
A single dose of enterolactone activates estrogen signaling and regulates expression of circadian clock genes in mice. The Journal of nutrition, 2011, Volume: 141, Issue:9 Topics: 4-Butyrolactone; Animals; Circadian Clocks; CLOCK Proteins; Estradiol; Estrogens; Female; Gene Expression Regulation; Lignans; Liver; Luciferases; Male; Mice; Mice, Inbred C57BL; Orchiectomy; Ovariectomy; Phytoestrogens; Protein Array Analysis; Random Allocation; Signal Transduction; Uterus	2011
Antiproliferative activity of lignans against the breast carcinoma cell lines MCF 7 and BT 20. Archives of gynecology and obstetrics, 2012, Volume: 285, Issue:4 Topics: 4-Butyrolactone; Anticarcinogenic Agents; Breast Neoplasms; Butylene Glycols; Cell Line, Tumor; Cell Proliferation; Estradiol; Estrogens; Female; Furans; Humans; Lignans; Phytoestrogens; Selective Estrogen Receptor Modulators; Tamoxifen	2012
The association between dietary lignans, phytoestrogen-rich foods, and fiber intake and postmenopausal breast cancer risk: a German case-control study. Nutrition and cancer, 2012, Volume: 64, Issue:5 Topics: 4-Butyrolactone; Aged; Breast Neoplasms; Carcinoma; Case-Control Studies; Cucurbita; Diet; Dietary Fiber; Female; Germany; Glycine max; Helianthus; Humans; Lignans; Middle Aged; Phytoestrogens; Postmenopause; Risk; Seeds	2012
Validation of FFQ-based assessment of dietary lignans compared with serum enterolactone in Swedish women. The British journal of nutrition, 2013, May-28, Volume: 109, Issue:10 Topics: 4-Butyrolactone; Aged; Biomarkers; Diet; Female; Humans; Lignans; Middle Aged; Obesity; Phytoestrogens; Reproducibility of Results; Surveys and Questionnaires; Sweden	2013
Interaction effects between genes involved in the AKT signaling pathway and phytoestrogens in gastric carcinogenesis: a nested case-control study from the Korean Multi-Center Cancer Cohort. Molecular nutrition & food research, 2012, Volume: 56, Issue:11 Topics: 4-Butyrolactone; Aged; Anticarcinogenic Agents; Asian People; Case-Control Studies; CDC2 Protein Kinase; Equol; fas Receptor; Female; Gene-Environment Interaction; Genetic Predisposition to Disease; Genistein; Humans; Isoflavones; Lignans; Male; MAP Kinase Kinase Kinase 1; Middle Aged; Odds Ratio; Phytoestrogens; Polymorphism, Single Nucleotide; Proto-Oncogene Proteins c-akt; Republic of Korea; Signal Transduction; Stomach Neoplasms	2012
Plasma enterolactone and incidence of endometrial cancer in a case-cohort study of Danish women. The British journal of nutrition, 2013, Jun-28, Volume: 109, Issue:12 Topics: 4-Butyrolactone; Cohort Studies; Denmark; Diet Surveys; Endometrial Neoplasms; Female; Fluoroimmunoassay; Hormone Replacement Therapy; Humans; Incidence; Lignans; Middle Aged; Phytoestrogens; Proportional Hazards Models; Surveys and Questionnaires	2013
Sociodemographic and lifestyle variables are compound- and class-specific correlates of urine phytoestrogen concentrations in the U.S. population. The Journal of nutrition, 2013, Volume: 143, Issue:6 Topics: 4-Butyrolactone; Adult; Age Factors; Alcohol Drinking; Body Mass Index; Equol; Exercise; Female; Humans; Isoflavones; Life Style; Lignans; Male; Middle Aged; Nutrition Surveys; Phytoestrogens; Sex Factors; Smoking; Socioeconomic Factors; United States	2013
Dietary flavonol intake is associated with age of puberty in a longitudinal cohort of girls. Nutrition research (New York, N.Y.), 2013, Volume: 33, Issue:7 Topics: 4-Butyrolactone; Age Factors; Biomarkers; Breast; Child; Diet; Female; Flavonols; Hair; Humans; Lignans; Longitudinal Studies; Phytoestrogens; Plant Extracts; Puberty	2013
Higher urinary lignan concentrations in women but not men are positively associated with shorter time to pregnancy. The Journal of nutrition, 2014, Volume: 144, Issue:3 Topics: 4-Butyrolactone; Adolescent; Adult; Body Mass Index; Diet; Female; Humans; Isoflavones; Lignans; Male; Phytoestrogens; Pregnancy; Prospective Studies; Socioeconomic Factors; Time-to-Pregnancy; Young Adult	2014
Cardiometabolic risk factors are associated with high urinary enterolactone concentration, independent of urinary enterodiol concentration and dietary fiber intake in adults. The Journal of nutrition, 2014, Volume: 144, Issue:9 Topics: 4-Butyrolactone; Adult; Aged; Aged, 80 and over; Blood Glucose; Blood Pressure; C-Reactive Protein; Cardiovascular Diseases; Cholesterol, HDL; Dietary Fiber; Female; Humans; Lignans; Logistic Models; Male; Metabolic Syndrome; Middle Aged; Nutrition Surveys; Obesity; Odds Ratio; Phytoestrogens; Risk Factors; Triglycerides	2014
Urinary enterolactone is associated with obesity and metabolic alteration in men in the US National Health and Nutrition Examination Survey 2001-10. The British journal of nutrition, 2015, Feb-28, Volume: 113, Issue:4 Topics: 4-Butyrolactone; Adolescent; Adult; Age Factors; Aged; Body Mass Index; Child; Cross-Sectional Studies; Down-Regulation; Female; Humans; Lignans; Logistic Models; Male; Metabolic Syndrome; Middle Aged; Nutrition Surveys; Obesity; Phytoestrogens; Sex Characteristics; United States; Waist Circumference; Young Adult	2015
Comparative pharmacokinetics of purified flaxseed and associated mammalian lignans in male Wistar rats. The British journal of nutrition, 2015, Mar-14, Volume: 113, Issue:5 Topics: 4-Butyrolactone; Administration, Oral; Animals; Biological Availability; Butylene Glycols; Dietary Supplements; Dose-Response Relationship, Drug; Estrogens; Flax; Glucosides; Half-Life; Injections, Intravenous; Intestinal Absorption; Kinetics; Lignans; Male; Metabolic Clearance Rate; Phytoestrogens; Random Allocation; Rats, Wistar; Seeds	2015
Urinary phytoestrogens and cancer, cardiovascular, and all-cause mortality in the continuous National Health and Nutrition Examination Survey. European journal of nutrition, 2016, Volume: 55, Issue:3 Topics: 4-Butyrolactone; Adult; Biomarkers; Body Mass Index; Cardiovascular Diseases; Cross-Sectional Studies; Female; Follow-Up Studies; Humans; Isoflavones; Lignans; Male; Middle Aged; Mortality; Neoplasms; Nutrition Surveys; Phytoestrogens; Proportional Hazards Models; Risk Factors; Treatment Outcome	2016
Urinary enterolactone associated with liver enzyme levels in US adults: National Health and Nutrition Examination Survey (NHANES). The British journal of nutrition, 2015, Jul-14, Volume: 114, Issue:1 Topics: 4-Butyrolactone; Adult; Aged; Aged, 80 and over; Alanine Transaminase; Alkaline Phosphatase; Aspartate Aminotransferases; Cross-Sectional Studies; Female; gamma-Glutamyltransferase; Humans; Lignans; Liver; Logistic Models; Male; Middle Aged; Nutrition Surveys; Phytoestrogens; United States	2015
Urinary Phytoestrogens Are Associated with Subtle Indicators of Semen Quality among Male Partners of Couples Desiring Pregnancy. The Journal of nutrition, 2015, Volume: 145, Issue:11 Topics: 4-Butyrolactone; Adult; Body Mass Index; Cholesterol; Cotinine; DNA Fragmentation; Endpoint Determination; Female; Fertility; Genistein; Humans; Isoflavones; Lignans; Linear Models; Male; Phytoestrogens; Pregnancy; Prospective Studies; Semen Analysis	2015
Effects of an equol-producing bacterium isolated from human faeces on isoflavone and lignan metabolism in mice. Journal of the science of food and agriculture, 2016, Volume: 96, Issue:9 Topics: 4-Butyrolactone; Actinobacteria; Animals; Equol; Feces; Female; Gastrointestinal Microbiome; Humans; Isoflavones; Lignans; Lipids; Mice; Mice, Inbred ICR; Phytoestrogens	2016
Occurrence and Profiles of the Artificial Endocrine Disruptor Bisphenol A and Natural Endocrine Disruptor Phytoestrogens in Urine from Children in China. International journal of environmental research and public health, 2015, Nov-30, Volume: 12, Issue:12 Topics: 4-Butyrolactone; Benzhydryl Compounds; Child; China; Chromatography, Liquid; Endocrine Disruptors; Environmental Monitoring; Female; Humans; Isoflavones; Lignans; Male; Phenols; Phytoestrogens; Risk Assessment; Tandem Mass Spectrometry; United States	2015
Effects of Phytoestrogen Extracts Isolated from Elder Flower on Hormone Production and Receptor Expression of Trophoblast Tumor Cells JEG-3 and BeWo, as well as MCF7 Breast Cancer Cells. Nutrients, 2016, Oct-08, Volume: 8, Issue:10 Topics: 4-Butyrolactone; Cell Line, Tumor; Cell Proliferation; Enzyme-Linked Immunosorbent Assay; Estradiol; Female; Humans; Immunohistochemistry; Lignans; MCF-7 Cells; Phytoestrogens; Plant Extracts; Pregnancy; Progesterone; Receptors, Estrogen; Sambucus; Trophoblastic Neoplasms; Uterine Neoplasms	2016
Performance and egg quality of laying hens fed flaxseed: highlights on n-3 fatty acids, cholesterol, lignans and isoflavones. Animal : an international journal of animal bioscience, 2017, Volume: 11, Issue:4 Topics: 4-Butyrolactone; alpha-Linolenic Acid; Animal Feed; Animals; Butylene Glycols; Chickens; Cholesterol; Diet; Dietary Supplements; Eggs; Fatty Acids; Fatty Acids, Omega-3; Female; Flax; Isoflavones; Lignans; Phytoestrogens; Seeds	2017
Effect of Antibiotics and Diet on Enterolactone Concentration and Metabolome Studied by Targeted and Nontargeted LC-MS Metabolomics. Journal of proteome research, 2017, 06-02, Volume: 16, Issue:6 Topics: 4-Butyrolactone; Animals; Anti-Bacterial Agents; Cholesterol, LDL; Chromatography, Liquid; Diet; Gastrointestinal Microbiome; Lignans; Lipid Metabolism; Mass Spectrometry; Metabolome; Metabolomics; Phytoestrogens; Swine	2017
Incomplete metabolism of phytoestrogens by gut microbiota from children under the age of three. International journal of food sciences and nutrition, 2018, Volume: 69, Issue:3 Topics: 4-Butyrolactone; Adult; Butylene Glycols; Case-Control Studies; Child, Preschool; Coumarins; Equol; Feces; Female; Furans; Gastrointestinal Microbiome; Humans; Hydrolyzable Tannins; Infant; Isoflavones; Lignans; Male; Phytoestrogens; Polyphenols	2018
Genistein and enterolactone in relation to Ki-67 expression and HER2 status in postmenopausal breast cancer patients. Molecular nutrition & food research, 2017, Volume: 61, Issue:11 Topics: 4-Butyrolactone; Aged; Breast Carcinoma In Situ; Breast Neoplasms; Case-Control Studies; Cell Proliferation; Female; Genistein; Germany; Humans; Isoflavones; Ki-67 Antigen; Lignans; Middle Aged; Neoplasm Grading; Neoplasm Invasiveness; Phytoestrogens; Postmenopause; Prognosis; Receptor, ErbB-2; Tumor Burden	2017
Enterolactone has stronger effects than enterodiol on ovarian cancer. Journal of ovarian research, 2017, Jul-24, Volume: 10, Issue:1 Topics: 4-Butyrolactone; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Cell Survival; Female; Humans; Lignans; Mice, Inbred BALB C; Mice, Nude; Ovarian Neoplasms; Phytoestrogens; Tumor Burden; Wound Healing	2017
Plasma phytoestrogens concentration and risk of colorectal cancer in two different Asian populations. Clinical nutrition (Edinburgh, Scotland), 2018, Volume: 37, Issue:5 Topics: 4-Butyrolactone; Adult; Aged; Asian People; Case-Control Studies; Colorectal Neoplasms; Female; Genistein; Humans; Isoflavones; Lignans; Male; Middle Aged; Phytoestrogens; Republic of Korea; Risk Factors; Vietnam	2018
Pre-diagnostic plasma enterolactone concentrations and breast cancer prognosis among postmenopausal women - The Danish Diet, Cancer and Health cohort. Clinical nutrition (Edinburgh, Scotland), 2018, Volume: 37, Issue:6 Pt A Topics: 4-Butyrolactone; Aged; Breast Neoplasms; Cohort Studies; Denmark; Female; Humans; Lignans; Middle Aged; Phytoestrogens; Postmenopause; Prognosis	2018
The effect of enterolactone on sphingolipid pathway and hepatic insulin resistance development in HepG2 cells. Life sciences, 2019, Jan-15, Volume: 217 Topics: 4-Butyrolactone; Ceramides; Hep G2 Cells; Humans; Insulin; Insulin Resistance; Lignans; Lipid Metabolism; Liver; Phytoestrogens; Signal Transduction; Sphingolipids	2019
A rapid UHPLC-MS/MS method for quantitation of phytoestrogens and the distribution of enterolactone in an Alabama estuary. Chemosphere, 2019, Volume: 237 Topics: 4-Butyrolactone; Alabama; Chromatography, High Pressure Liquid; Endocrine Disruptors; Environmental Monitoring; Estuaries; Humans; Lignans; Phytoestrogens; Tandem Mass Spectrometry; Wastewater; Water Pollutants, Chemical	2019
Prognostic associations of circulating phytoestrogens and biomarker changes in long-term survivors of postmenopausal breast cancer. Nutrition and cancer, 2020, Volume: 72, Issue:7 Topics: 4-Butyrolactone; Aged; Biomarkers, Tumor; Breast Neoplasms; Case-Control Studies; Cohort Studies; Female; Genistein; Germany; Humans; Lignans; Middle Aged; Phytoestrogens; Postmenopause; Prognosis; Proportional Hazards Models; Prospective Studies; Survival Analysis; Survivors	2020
Associations of Urinary Phytoestrogen Concentrations with Sleep Disorders and Sleep Duration among Adults. Nutrients, 2020, Jul-16, Volume: 12, Issue:7 Topics: 4-Butyrolactone; Adult; Age Factors; Aged; Biomarkers; Cross-Sectional Studies; Female; Humans; Isoflavones; Lignans; Male; Middle Aged; Phytoestrogens; Racial Groups; Sex Factors; Sleep; Sleep Wake Disorders	2020
The Association between Plasma Concentration of Phytoestrogens and Hypertension within the Korean Multicenter Cancer Cohort. Nutrients, 2021, Dec-05, Volume: 13, Issue:12 Topics: 4-Butyrolactone; Asian People; Biomarkers; Case-Control Studies; Cohort Studies; Equol; Female; Humans; Hypertension; Lignans; Logistic Models; Male; Phytoestrogens; Republic of Korea; Risk	2021
Validation of ELISAs for Isoflavones and Enterolactone for Phytoestrogen Intake Assessment in the French Population. Nutrients, 2023, Feb-15, Volume: 15, Issue:4 Topics: Diet; Humans; Isoflavones; Lignans; Phytoestrogens	2023
Urinary phytoestrogens and the risk of uterine leiomyomata in US women. BMC women's health, 2023, 05-13, Volume: 23, Issue:1 Topics: Bayes Theorem; Cross-Sectional Studies; Equol; Female; Genistein; Humans; Leiomyoma; Nutrition Surveys; Phytoestrogens	2023