2,3-bis(3'-hydroxybenzyl)butyrolactone and daidzein

2,3-bis(3'-hydroxybenzyl)butyrolactone has been researched along with daidzein in 29 studies

Compound Research Comparison

Studies (2,3-bis(3'-hydroxybenzyl)butyrolactone)	Trials (2,3-bis(3'-hydroxybenzyl)butyrolactone)	Recent Studies (post-2010) (2,3-bis(3'-hydroxybenzyl)butyrolactone)	Studies (daidzein)	Trials (daidzein)	Recent Studies (post-2010) (daidzein)
319	32	124	1,885	136	753

Protein Interaction Comparison

Protein	Taxonomy	daidzein (IC50)
rac GTPase-activating protein 1 isoform a	Homo sapiens (human)	91.26
Estrogen receptor	Homo sapiens (human)	2.97
Aldehyde dehydrogenase, mitochondrial	Homo sapiens (human)	9
UDP-glucuronosyltransferase 1A1	Homo sapiens (human)	7.3
Transporter	Rattus norvegicus (Norway rat)	0.45
Estrogen receptor beta	Homo sapiens (human)	1.6568

Research

Studies (29)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (3.45)	18.7374
1990's	9 (31.03)	18.2507
2000's	12 (41.38)	29.6817
2010's	7 (24.14)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Adlercreutz, H; Bannwart, C; Brunow, G; Fotsis, T; Hase, T; Wähälä, K	1
Adlercreutz, H; Bannwart, C; Brunow, G; Fotsis, T; Hase, T; Mäkelä, T; Musey, PI; Wähälä, K	1
Campbell, DR; Kirkman, LM; Lampe, JW; Martini, MC; Slavin, JL	1
Hutchins, AM; Lampe, JW; Slavin, JL	1
Griffiths, K; Morton, MS; Wahlqvist, ML; Wilcox, G	1
Benassayag, C; Haourigui, M; Martin, ME; Nunez, EA; Pelissero, C	1
Abranches-Monteiro, L; Blacklock, N; Chan, PS; Cheng, C; Correia, R; Griffiths, K; Lloyd, S; Matos-Ferreira, A; Morton, MS	1
Adlercreutz, H; Akhmedkhanov, A; Toniolo, P; Zeleniuch-Jacquotte, A	1
Brüggemann-Rotgans, IE; Kardinaal, AF; Morton, MS; van Beresteijn, EC	1
Adlercreutz, H; Al-Maharik, N; Hampl, R; Lapcík, O; Mäkelä, T; Mikola, H; Uehara, M; Wähälä, K	1
Adlercreutz, H; Pietinen, P; Puska, P; Stumpf, K	1
Adlercreutz, H; Arai, Y; Uehar, M; Watanabe, S	1
Bacigalupo, MA; Ius, A; Piazza, F; Roda, A; Setchell, KD; Simoni, P	1
Ayton, R; Dalais, FS; Grehan, M; Medley, G; Murkies, AL; Rice, GE; Strauss, BJ; Wahlqvist, ML	1
Arisaka, O; Evans, BA; Miyake, N; Morgan, LD; Morton, MS	1
Bingham, SA; Botting, NP; Fryatt, T; Grace, PB; Oldfield, MF; Taylor, JI	1
Andre, F; Antignac, JP; Cariou, R; Cravedi, JP; Le Bizec, B	1
Liu, Z; Moline, J; Wolff, MS	1
Engel, SM; Kaplan, D; Levy, B; Liu, Z; Wolff, MS	1
Bingham, SA; Day, NE; Doody, D; Dowsett, M; Dunning, AM; Folkerd, E; Grace, PB; Khaw, KT; Low, YL; Luben, RN; Mulligan, AA; Scollen, S; Taylor, JI; Wareham, NJ; Welch, AA	1
Alexander, FE; Bolton-Smith, C; Heald, CL; Morton, MS; Ritchie, MR	1
Antignac, JP; Dip, R; Gmuender, H; Le Bizec, B; Lenz, S; Naegeli, H	1
Chang, SH; Cho, LY; Choi, BY; Han, DS; Kang, D; Kim, YS; Ko, KP; Ma, SH; Park, SK; Shin, A; Shin, HR; Song, KS; Yang, JJ; Yoo, KY	1
Chang, SH; Cho, LY; Choi, BY; Han, DS; Kang, D; Kim, HJ; Kim, YS; Ko, KP; Ma, SH; Park, SK; Shin, A; Shin, HR; Song, KS; Yang, JJ; Yoo, KY	1
Jones, J; Liu, Z; Reger, MK; Zhang, J; Zollinger, TW	1
Boyd Barr, D; Buck Louis, GM; Chen, Z; Kim, S; Mumford, SL	1
Hori, S; Nakagawa, H; Sugahara, T; Tamura, M; Yamauchi, S	1
Duan, Z; Li, K; Liu, Z; Wang, L; Wu, Y; Zhang, M	1
Chang, SH; Kang, CH; Kang, D; Kim, CS; Ko, KP; Koriyama, C; Lim, YK; Ngoan, LT; Park, SK; Shin, HR; Tokudome, S; Yeo, Y; Yoo, KY; Yoon, JH	1

Reviews

1 review(s) available for 2,3-bis(3'-hydroxybenzyl)butyrolactone and daidzein

Article	Year
Gene polymorphisms in the ornithine decarboxylase-polyamine pathway modify gastric cancer risk by interaction with isoflavone concentrations. Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 2015, Volume: 18, Issue:3 Topics: 4-Butyrolactone; Adenosylmethionine Decarboxylase; Asian People; Case-Control Studies; Equol; Gene-Environment Interaction; Genistein; Humans; Isoflavones; Lignans; Multicenter Studies as Topic; NAD(P)H Dehydrogenase (Quinone); Nitric Oxide Synthase Type II; Ornithine Decarboxylase; Phytoestrogens; Polyamines; Polymorphism, Single Nucleotide; Stomach Neoplasms	2015

Article

Year

Gene polymorphisms in the ornithine decarboxylase-polyamine pathway modify gastric cancer risk by interaction with isoflavone concentrations.

Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 2015, Volume: 18, Issue:3

Topics: 4-Butyrolactone; Adenosylmethionine Decarboxylase; Asian People; Case-Control Studies; Equol; Gene-Environment Interaction; Genistein; Humans; Isoflavones; Lignans; Multicenter Studies as Topic; NAD(P)H Dehydrogenase (Quinone); Nitric Oxide Synthase Type II; Ornithine Decarboxylase; Phytoestrogens; Polyamines; Polymorphism, Single Nucleotide; Stomach Neoplasms

2015

Trials

3 trial(s) available for 2,3-bis(3'-hydroxybenzyl)butyrolactone and daidzein

Article	Year
Urinary lignan and isoflavonoid excretion in men and women consuming vegetable and soy diets. Nutrition and cancer, 1995, Volume: 24, Issue:1 Topics: 4-Butyrolactone; Adult; Chromans; Colon; Cross-Over Studies; Diet; Equol; Female; Gas Chromatography-Mass Spectrometry; Genistein; Glycine max; Humans; Isoflavones; Lignans; Male; Sex Characteristics; Vegetables	1995
Urinary isoflavonoid phytoestrogen and lignan excretion after consumption of fermented and unfermented soy products. Journal of the American Dietetic Association, 1995, Volume: 95, Issue:5 Topics: 4-Butyrolactone; Adult; Chromans; Cross-Over Studies; Defecation; Diet; Equol; Estrogens; Estrogens, Non-Steroidal; Fermentation; Food Handling; Genistein; Glycine max; Humans; Isoflavones; Lignans; Male; Phytoestrogens; Plant Preparations; Taste	1995
Effects of dietary phytoestrogens in postmenopausal women. Climacteric : the journal of the International Menopause Society, 1998, Volume: 1, Issue:2 Topics: 4-Butyrolactone; Aged; Bone Density; Diet; Double-Blind Method; Estrogens, Non-Steroidal; Female; Genistein; Glycine max; Hot Flashes; Humans; Isoflavones; Lignans; Linseed Oil; Middle Aged; Phytoestrogens; Plant Preparations; Postmenopause; Triticum	1998

Other Studies

25 other study(ies) available for 2,3-bis(3'-hydroxybenzyl)butyrolactone and daidzein

Article	Year
Isotope dilution gas chromatographic-mass spectrometric method for the determination of lignans and isoflavonoids in human urine, including identification of genistein. Clinica chimica acta; international journal of clinical chemistry, 1991, Jul-15, Volume: 199, Issue:3 Topics: 4-Butyrolactone; Butylene Glycols; Chromans; Equol; Female; Furans; Gas Chromatography-Mass Spectrometry; Genistein; Humans; Indicator Dilution Techniques; Isoflavones; Lignans; Lignin; Magnetic Resonance Spectroscopy; Male	1991
Identification of lignans and phytoestrogens in urine of chimpanzees. Clinica chimica acta; international journal of clinical chemistry, 1986, Jul-30, Volume: 158, Issue:2 Topics: 4-Butyrolactone; Animals; Butylene Glycols; Chromans; Diet; Equol; Estrogens; Estrogens, Non-Steroidal; Isoflavones; Lignans; Male; Pan troglodytes; Phytoestrogens; Plant Extracts; Plant Preparations	1986
Determination of lignans and isoflavonoids in human female plasma following dietary supplementation. The Journal of endocrinology, 1994, Volume: 142, Issue:2 Topics: 4-Butyrolactone; Australia; Chromans; Diet; Equol; Estrogens; Female; Food, Fortified; Gas Chromatography-Mass Spectrometry; Genistein; Glycine max; Humans; Isoflavones; Lignans; Linseed Oil; Middle Aged; Monoamine Oxidase Inhibitors; Neoplasms; Plants, Edible; Postmenopause	1994
Interactions between phytoestrogens and human sex steroid binding protein. Life sciences, 1996, Volume: 58, Issue:5 Topics: 4-Butyrolactone; Electrophoresis, Polyacrylamide Gel; Estradiol; Estrogens, Non-Steroidal; Genistein; Humans; Immunoelectrophoresis, Two-Dimensional; Isoflavones; Kinetics; Lignans; Masoprocol; Phytoestrogens; Plant Preparations; Plants; Sex Hormone-Binding Globulin; Structure-Activity Relationship; Testosterone	1996
Lignans and isoflavonoids in plasma and prostatic fluid in men: samples from Portugal, Hong Kong, and the United Kingdom. The Prostate, 1997, Jul-01, Volume: 32, Issue:2 Topics: 4-Butyrolactone; Adult; Aged; Chromans; Equol; Gas Chromatography-Mass Spectrometry; Hong Kong; Humans; Isoflavones; Lignans; Male; Middle Aged; Portugal; Prostate; Semen; United Kingdom	1997
Reliability of serum measurements of lignans and isoflavonoid phytoestrogens over a two-year period. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 1998, Volume: 7, Issue:10 Topics: 4-Butyrolactone; Adult; Age Factors; Aged; Bias; Breast Neoplasms; Chromans; Equol; Feasibility Studies; Female; Genistein; Humans; Isoflavones; Lignans; Middle Aged; New York City; Pilot Projects; Postmenopause; Premenopause; Reference Values; Reproducibility of Results; Sensitivity and Specificity; Time Factors	1998
Phyto-oestrogen excretion and rate of bone loss in postmenopausal women. European journal of clinical nutrition, 1998, Volume: 52, Issue:11 Topics: 4-Butyrolactone; Aging; Bone Density; Chromans; Equol; Estrogens, Non-Steroidal; Female; Gas Chromatography-Mass Spectrometry; Genistein; Humans; Isoflavones; Lignans; Linear Models; Middle Aged; Osteoporosis, Postmenopausal; Phytoestrogens; Plant Preparations; Postmenopause; Prospective Studies; Time Factors	1998
Rapid analysis of phytoestrogens in human urine by time-resolved fluoroimmunoassay. The Journal of steroid biochemistry and molecular biology, 2000, Volume: 72, Issue:5 Topics: 4-Butyrolactone; Animals; Cross Reactions; Estrogens, Non-Steroidal; Evaluation Studies as Topic; Female; Fluoroimmunoassay; Gas Chromatography-Mass Spectrometry; Genistein; Humans; Isoflavones; Lignans; Phytoestrogens; Plant Preparations; Rabbits; Sensitivity and Specificity; Serum Albumin, Bovine	2000
Changes in serum enterolactone, genistein, and daidzein in a dietary intervention study in Finland. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2000, Volume: 9, Issue:12 Topics: 4-Butyrolactone; Adult; Biomarkers; Dietary Fats; Dietary Fats, Unsaturated; Estrogens; Finland; Fruit; Genistein; Humans; Isoflavones; Lignans; Middle Aged; Vegetables	2000
Comparison of plasma and urinary phytoestrogens in Japanese and Finnish women by time-resolved fluoroimmunoassay. BioFactors (Oxford, England), 2000, Volume: 12, Issue:1-4 Topics: 4-Butyrolactone; Adult; Aged; Diet; Estrogens, Non-Steroidal; Europium; Female; Finland; Fluoroimmunoassay; Gas Chromatography-Mass Spectrometry; Genistein; Humans; Isoflavones; Japan; Lignans; Middle Aged; Phytoestrogens; Plant Preparations; Reference Values; Sensitivity and Specificity	2000
Analytical performance of luminescent immunoassays of different format for serum daidzein analysis. Fresenius' journal of analytical chemistry, 2001, Volume: 370, Issue:1 Topics: 4-Butyrolactone; Cross Reactions; Dose-Response Relationship, Immunologic; Equilin; Female; Fluorescent Dyes; Genistein; Haptens; Horseradish Peroxidase; Humans; Immunoenzyme Techniques; Immunoglobulin Fc Fragments; Isoflavones; Lignans; Luminescent Measurements; Molecular Structure; Phenanthrolines; Polystyrenes; Radioimmunoassay; Serum Albumin, Bovine; Steroids	2001
Phytoestrogen concentrations in serum from Japanese men and women over forty years of age. The Journal of nutrition, 2002, Volume: 132, Issue:10 Topics: 4-Butyrolactone; Adult; Aged; Aged, 80 and over; Breast Neoplasms; Chromans; Diet; Equol; Estrogens, Non-Steroidal; Female; Gas Chromatography-Mass Spectrometry; Genistein; Humans; Isoflavones; Japan; Lignans; Male; Middle Aged; Phytoestrogens; Plant Preparations; Prostatic Neoplasms; United Kingdom	2002
Quantification of isoflavones and lignans in urine using gas chromatography/mass spectrometry. Analytical biochemistry, 2003, Apr-01, Volume: 315, Issue:1 Topics: 4-Butyrolactone; Equol; Female; Gas Chromatography-Mass Spectrometry; Genistein; Humans; Isoflavones; Lignans; Molecular Structure; Phytoestrogens; Plant Preparations; Reproducibility of Results; Sensitivity and Specificity	2003
Identification of phytoestrogens in bovine milk using liquid chromatography/electrospray tandem mass spectrometry. Rapid communications in mass spectrometry : RCM, 2003, Volume: 17, Issue:12 Topics: 4-Butyrolactone; Animals; Cattle; Chromans; Chromatography, Liquid; Coumestrol; Equol; Estrogens, Non-Steroidal; Genistein; Ions; Isoflavones; Lignans; Milk; Molecular Structure; Phytoestrogens; Plant Preparations; Spectrometry, Mass, Electrospray Ionization	2003
Analysis of environmental biomarkers in urine using an electrochemical detector. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2005, May-05, Volume: 819, Issue:1 Topics: 4-Butyrolactone; Benzhydryl Compounds; Biomarkers; Child; Chromatography, High Pressure Liquid; Electrochemistry; Environmental Exposure; Female; Genistein; Humans; Isoflavones; Lignans; Middle Aged; Phenols; Phytoestrogens	2005
Xenobiotic phenols in early pregnancy amniotic fluid. Reproductive toxicology (Elmsford, N.Y.), 2006, Volume: 21, Issue:1 Topics: 4-Butyrolactone; Amniotic Fluid; Benzhydryl Compounds; Estrogens, Non-Steroidal; Female; Genistein; Humans; Isoflavones; Lignans; Maternal Exposure; Maternal-Fetal Exchange; Phenols; Phytoestrogens; Pregnancy; Xenobiotics	2006
Polymorphisms in the CYP19 gene may affect the positive correlations between serum and urine phytoestrogen metabolites and plasma androgen concentrations in men. The Journal of nutrition, 2005, Volume: 135, Issue:11 Topics: 4-Butyrolactone; Aged; Androgens; Androstane-3,17-diol; Aromatase; Diet; Equol; Genistein; Genotype; Humans; Isoflavones; Lignans; Male; Middle Aged; Phytoestrogens; Polymorphism, Genetic; Sex Hormone-Binding Globulin; Testosterone	2005
Phyto-oestrogens and risk of prostate cancer in Scottish men. The British journal of nutrition, 2007, Volume: 98, Issue:2 Topics: 4-Butyrolactone; Aged; Case-Control Studies; Diet; Diet Surveys; Energy Intake; Equol; Genistein; Humans; Isoflavones; Lignans; Male; Middle Aged; Phytoestrogens; Prostatic Neoplasms; Risk Assessment; Scotland	2007
Global gene expression profiles induced by phytoestrogens in human breast cancer cells. Endocrine-related cancer, 2008, Volume: 15, Issue:1 Topics: 4-Butyrolactone; Animals; Biomarkers, Tumor; Breast Neoplasms; Cattle; Estradiol; Estrogen Receptor beta; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genistein; Humans; Isoflavones; Lignans; Milk; Neoplasm Proteins; Oligonucleotide Array Sequence Analysis; Phytoestrogens; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Soy Milk; Tumor Cells, Cultured	2008
Interaction effects between genes involved in the AKT signaling pathway and phytoestrogens in gastric carcinogenesis: a nested case-control study from the Korean Multi-Center Cancer Cohort. Molecular nutrition & food research, 2012, Volume: 56, Issue:11 Topics: 4-Butyrolactone; Aged; Anticarcinogenic Agents; Asian People; Case-Control Studies; CDC2 Protein Kinase; Equol; fas Receptor; Female; Gene-Environment Interaction; Genetic Predisposition to Disease; Genistein; Humans; Isoflavones; Lignans; Male; MAP Kinase Kinase Kinase 1; Middle Aged; Odds Ratio; Phytoestrogens; Polymorphism, Single Nucleotide; Proto-Oncogene Proteins c-akt; Republic of Korea; Signal Transduction; Stomach Neoplasms	2012
Urinary phytoestrogens and cancer, cardiovascular, and all-cause mortality in the continuous National Health and Nutrition Examination Survey. European journal of nutrition, 2016, Volume: 55, Issue:3 Topics: 4-Butyrolactone; Adult; Biomarkers; Body Mass Index; Cardiovascular Diseases; Cross-Sectional Studies; Female; Follow-Up Studies; Humans; Isoflavones; Lignans; Male; Middle Aged; Mortality; Neoplasms; Nutrition Surveys; Phytoestrogens; Proportional Hazards Models; Risk Factors; Treatment Outcome	2016
Urinary Phytoestrogens Are Associated with Subtle Indicators of Semen Quality among Male Partners of Couples Desiring Pregnancy. The Journal of nutrition, 2015, Volume: 145, Issue:11 Topics: 4-Butyrolactone; Adult; Body Mass Index; Cholesterol; Cotinine; DNA Fragmentation; Endpoint Determination; Female; Fertility; Genistein; Humans; Isoflavones; Lignans; Linear Models; Male; Phytoestrogens; Pregnancy; Prospective Studies; Semen Analysis	2015
Effects of an equol-producing bacterium isolated from human faeces on isoflavone and lignan metabolism in mice. Journal of the science of food and agriculture, 2016, Volume: 96, Issue:9 Topics: 4-Butyrolactone; Actinobacteria; Animals; Equol; Feces; Female; Gastrointestinal Microbiome; Humans; Isoflavones; Lignans; Lipids; Mice; Mice, Inbred ICR; Phytoestrogens	2016
Occurrence and Profiles of the Artificial Endocrine Disruptor Bisphenol A and Natural Endocrine Disruptor Phytoestrogens in Urine from Children in China. International journal of environmental research and public health, 2015, Nov-30, Volume: 12, Issue:12 Topics: 4-Butyrolactone; Benzhydryl Compounds; Child; China; Chromatography, Liquid; Endocrine Disruptors; Environmental Monitoring; Female; Humans; Isoflavones; Lignans; Male; Phenols; Phytoestrogens; Risk Assessment; Tandem Mass Spectrometry; United States	2015
Plasma phytoestrogens concentration and risk of colorectal cancer in two different Asian populations. Clinical nutrition (Edinburgh, Scotland), 2018, Volume: 37, Issue:5 Topics: 4-Butyrolactone; Adult; Aged; Asian People; Case-Control Studies; Colorectal Neoplasms; Female; Genistein; Humans; Isoflavones; Lignans; Male; Middle Aged; Phytoestrogens; Republic of Korea; Risk Factors; Vietnam	2018