Compounds > 2,3-bis(3'-hydroxybenzyl)butane-1,4-diol

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2,3-bis(3'-hydroxybenzyl)butane-1,4-diol and glucose, (beta-d)-isomer

2,3-bis(3'-hydroxybenzyl)butane-1,4-diol has been researched along with glucose, (beta-d)-isomer in 19 studies

Compound Research Comparison

Studies (2,3-bis(3'-hydroxybenzyl)butane-1,4-diol)	Trials (2,3-bis(3'-hydroxybenzyl)butane-1,4-diol)	Recent Studies (post-2010) (2,3-bis(3'-hydroxybenzyl)butane-1,4-diol)	Studies (glucose, (beta-d)-isomer)	Trials (glucose, (beta-d)-isomer)	Recent Studies (post-2010) (glucose, (beta-d)-isomer)
131	12	47	21,956	883	10,747

Research

Studies (19)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (5.26)	18.2507
2000's	8 (42.11)	29.6817
2010's	7 (36.84)	24.3611
2020's	3 (15.79)	2.80

Authors

Authors	Studies
Kitts, DD; Thompson, LU; Wijewickreme, AN; Yuan, YV	1
Hattori, M; Li, Y; Meselhy, MR; Qin, GW; Wang, LQ	1
Arts, IC; Hollman, PC; Kuijsten, A; Vree, TB	1
Alpert, CA; Blaut, M; Clavel, T; Doré, J; Henderson, G; Philippe, C; Rigottier-Gois, L	1
Blaut, M; Clavel, T; Doré, J; Engst, W; Henderson, G	1
Hu, C; Kitts, DD; Yuan, YV	1
Akao, T; Hattori, M; Jin, JS; Kakiuchi, N; Min, BS; Nakamura, N; Zhao, YF	1
Aida, K; Fukumitsu, S; Kobori, M; Ozawa, S; Takahashi, Y; Ueno, N	1
Cao, R; Cui, S; Gagnon, N; Mir, PS; Petit, HV	1
Amaretti, A; Leonardi, A; Raimondi, S; Roncaglia, L; Rossi, M	1
Debouche, C; During, A; Larondelle, Y; Raas, T	1
Bastías, JM; Estévez, AM; Figuerola, F; Fuentealba, C; Muñoz, O	1
Alcorn, J; Krol, ES; Michel, D; Muir, AD; Mukker, JK	1
Jan, KC; Liu, TC; Yang, BB	1
Alcorn, J; Krol, ES; Muir, AD; Mukker, JK; Singh, RS	1
Amaretti, A; García-Villalba, R; Leonardi, A; Quartieri, A; Raimondi, S; Rossi, M; Tomàs-Barberàn, F	1
Dhaini, J; Haykal, T; Hodroj, MH; Rizk, S; Tannous, S	1
Feng, X; Liu, L; Ma, CM; Xu, HY; Zhang, G; Zhang, L; Zheng, Z; Zhuang, CC	1
Alcorn, J; Guo, Y; Mustafa, R; Purdy, SK; Reaney, MJT; Shen, J; Tse, TJ; Yang, X	1

Trials

1 trial(s) available for 2,3-bis(3'-hydroxybenzyl)butane-1,4-diol and glucose, (beta-d)-isomer

Article	Year
Technical note: Quantification of lignans in the urine, milk, and plasma of flaxseed cake-fed dairy sheep. Journal of dairy science, 2021, Volume: 104, Issue:1 Topics: 4-Butyrolactone; Animal Feed; Animals; Butylene Glycols; Flax; Glucosides; Lignans; Milk; Seeds; Sheep	2021

Other Studies

18 other study(ies) available for 2,3-bis(3'-hydroxybenzyl)butane-1,4-diol and glucose, (beta-d)-isomer

Article	Year
Antioxidant activity of the flaxseed lignan secoisolariciresinol diglycoside and its mammalian lignan metabolites enterodiol and enterolactone. Molecular and cellular biochemistry, 1999, Volume: 202, Issue:1-2 Topics: 4-Butyrolactone; Animals; Antioxidants; Butylene Glycols; Emulsions; Estrogens; Flax; Free Radical Scavengers; Glucosides; Hydroxides; Lignans; Linoleic Acid; Lipid Peroxidation; Mammals; Oxidation-Reduction; Seeds	1999
Human intestinal bacteria capable of transforming secoisolariciresinol diglucoside to mammalian lignans, enterodiol and enterolactone. Chemical & pharmaceutical bulletin, 2000, Volume: 48, Issue:11 Topics: 4-Butyrolactone; Animals; Butylene Glycols; Culture Media; Estrogens; Eubacterium; Feces; Glucosides; Humans; Intestines; Lignans; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Peptostreptococcus; Rats; Rats, Wistar	2000
Pharmacokinetics of enterolignans in healthy men and women consuming a single dose of secoisolariciresinol diglucoside. The Journal of nutrition, 2005, Volume: 135, Issue:4 Topics: 4-Butyrolactone; Adult; Blood Specimen Collection; Butylene Glycols; Dietary Supplements; Female; Glucosides; Humans; Lignans; Male; Reference Values	2005
Intestinal bacterial communities that produce active estrogen-like compounds enterodiol and enterolactone in humans. Applied and environmental microbiology, 2005, Volume: 71, Issue:10 Topics: 4-Butyrolactone; Actinobacteria; Adult; Bacteria, Anaerobic; Butylene Glycols; Colony Count, Microbial; Culture Media; Female; Flow Cytometry; Glucosides; Humans; In Situ Hybridization, Fluorescence; Intestines; Lignans; Male; Middle Aged; Peptostreptococcus; Phytoestrogens	2005
Phylogeny of human intestinal bacteria that activate the dietary lignan secoisolariciresinol diglucoside. FEMS microbiology ecology, 2006, Volume: 55, Issue:3 Topics: 4-Butyrolactone; Bacteria, Anaerobic; Butylene Glycols; Culture Media; Glucosides; Humans; Intestines; Lignans; Phylogeny	2006
Antioxidant activities of the flaxseed lignan secoisolariciresinol diglucoside, its aglycone secoisolariciresinol and the mammalian lignans enterodiol and enterolactone in vitro. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2007, Volume: 45, Issue:11 Topics: 4-Butyrolactone; Animals; Biphenyl Compounds; Butylene Glycols; Flax; Free Radical Scavengers; Glucosides; Hydrazines; Lignans; Liposomes; Mammals; Molecular Structure; Picrates; Seeds	2007
Enantioselective dehydroxylation of enterodiol and enterolactone precursors by human intestinal bacteria. Biological & pharmaceutical bulletin, 2007, Volume: 30, Issue:11 Topics: 4-Butyrolactone; Bacteria, Anaerobic; Biotransformation; Butylene Glycols; Eubacterium; Feces; Glucosides; Humans; Hydroxylation; Intestines; Lignans; Molecular Structure; Phylogeny; RNA, Bacterial; RNA, Ribosomal, 16S; Stereoisomerism	2007
Flaxseed lignan attenuates high-fat diet-induced fat accumulation and induces adiponectin expression in mice. The British journal of nutrition, 2008, Volume: 100, Issue:3 Topics: 3T3-L1 Cells; Adipocytes; Adiponectin; Animals; Butylene Glycols; Cholesterol; Dietary Fats; Flax; Glucosides; Insulin; Leptin; Lignans; Male; Mice; Mice, Inbred C57BL; Obesity; PPAR gamma; RNA, Messenger; Triglycerides	2008
Milk concentration of the mammalian lignan enterolactone, milk production, milk fatty acid profile, and digestibility in dairy cows fed diets containing whole flaxseed or flaxseed meal. The Journal of dairy research, 2009, Volume: 76, Issue:3 Topics: 4-Butyrolactone; Animals; Butylene Glycols; Cattle; Diet; Digestion; Fatty Acids; Flax; Glucosides; Lactation; Lignans; Male; Milk; Seeds	2009
Role of bifidobacteria in the activation of the lignan secoisolariciresinol diglucoside. Applied microbiology and biotechnology, 2011, Volume: 92, Issue:1 Topics: 4-Butyrolactone; Bifidobacterium; Biotransformation; Butylene Glycols; Glucosides; Lignans	2011
Among plant lignans, pinoresinol has the strongest antiinflammatory properties in human intestinal Caco-2 cells. The Journal of nutrition, 2012, Volume: 142, Issue:10 Topics: 4-Butyrolactone; Anti-Inflammatory Agents; Butylene Glycols; Caco-2 Cells; Cell Differentiation; Chemokine CCL2; Chromatography, High Pressure Liquid; Cyclooxygenase 2; Furans; Glucosides; Humans; Interleukin-1beta; Interleukin-6; Interleukin-8; Intestines; Lignans; NF-kappa B; Plant Extracts; Signal Transduction	2012
Bioaccessibility of lignans from flaxseed (Linum usitatissimum L.) determined by single-batch in vitro simulation of the digestive process. Journal of the science of food and agriculture, 2014, Volume: 94, Issue:9 Topics: 4-Butyrolactone; Bacteria, Anaerobic; Biological Availability; Butylene Glycols; Colon; Fatty Acids, Volatile; Fermentation; Flax; Glucosides; Humans; In Vitro Techniques; Lignans; Seeds	2014
Permeability and conjugative metabolism of flaxseed lignans by Caco-2 human intestinal cells. Journal of natural products, 2014, Jan-24, Volume: 77, Issue:1 Topics: 4-Butyrolactone; Algorithms; Butylene Glycols; Caco-2 Cells; Chromatography, High Pressure Liquid; Flax; Glucosides; Humans; Intestinal Mucosa; Lignans; Molecular Structure; Permeability	2014
Gene expression profiling of sesaminol triglucoside and its tetrahydrofuranoid metabolites in primary rat hepatocytes. International journal of food sciences and nutrition, 2014, Volume: 65, Issue:8 Topics: 4-Butyrolactone; Animals; ATP-Binding Cassette Transporters; Cytochrome P-450 Enzyme System; Dioxoles; Furans; Gene Expression; Gene Expression Profiling; Glucosides; Hepatocytes; Inactivation, Metabolic; Lignans; Liver; Mammals; Plant Extracts; Rats, Sprague-Dawley; Seeds; Sesamum	2014
Comparative pharmacokinetics of purified flaxseed and associated mammalian lignans in male Wistar rats. The British journal of nutrition, 2015, Mar-14, Volume: 113, Issue:5 Topics: 4-Butyrolactone; Administration, Oral; Animals; Biological Availability; Butylene Glycols; Dietary Supplements; Dose-Response Relationship, Drug; Estrogens; Flax; Glucosides; Half-Life; Injections, Intravenous; Intestinal Absorption; Kinetics; Lignans; Male; Metabolic Clearance Rate; Phytoestrogens; Random Allocation; Rats, Wistar; Seeds	2015
Detection of novel metabolites of flaxseed lignans in vitro and in vivo. Molecular nutrition & food research, 2016, Volume: 60, Issue:7 Topics: 4-Butyrolactone; Adult; Bifidobacterium pseudocatenulatum; Butylene Glycols; Dietary Supplements; Feces; Female; Flax; Furans; Gastrointestinal Microbiome; Glucosides; Humans; Intestinal Mucosa; Intestines; Lignans; Male; Middle Aged; Prebiotics; Probiotics; Young Adult	2016
The anti-cancer effect of flaxseed lignan derivatives on different acute myeloid leukemia cancer cells. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2020, Volume: 132 Topics: 4-Butyrolactone; Antineoplastic Agents, Phytogenic; Apoptosis; Butylene Glycols; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Child; Female; Flax; Glucosides; Humans; Leukemia, Myeloid, Acute; Lignans; Plant Extracts; Reactive Oxygen Species; Seeds	2020
Oral Pharmacokinetics of Enriched Secoisolariciresinol Diglucoside and Its Polymer in Rats. Journal of natural products, 2021, 06-25, Volume: 84, Issue:6 Topics: 4-Butyrolactone; Animals; Biological Availability; Butylene Glycols; Female; Flax; Glucosides; Lignans; Molecular Structure; Polymers; Rats; Rats, Wistar; Seeds	2021