Page last updated: 2024-09-03

2,3-bis(3'-hydroxybenzyl)butane-1,4-diol and equol

2,3-bis(3'-hydroxybenzyl)butane-1,4-diol has been researched along with equol in 17 studies

Compound Research Comparison

Studies
(2,3-bis(3'-hydroxybenzyl)butane-1,4-diol)
Trials
(2,3-bis(3'-hydroxybenzyl)butane-1,4-diol)
Recent Studies (post-2010)
(2,3-bis(3'-hydroxybenzyl)butane-1,4-diol)
Studies
(equol)
Trials
(equol)
Recent Studies (post-2010) (equol)
131124767290348

Protein Interaction Comparison

ProteinTaxonomy2,3-bis(3'-hydroxybenzyl)butane-1,4-diol (IC50)equol (IC50)
Estrogen receptorHomo sapiens (human)5.876
Estrogen receptor betaHomo sapiens (human)5.571

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19903 (17.65)18.7374
1990's8 (47.06)18.2507
2000's4 (23.53)29.6817
2010's1 (5.88)24.3611
2020's1 (5.88)2.80

Authors

AuthorsStudies
Adlercreutz, H; Bannwart, C; Brunow, G; Fotsis, T; Hase, T; Wähälä, K1
Adlercreutz, H; Benassayag, C; Garreau, B; Mäkelä, T; Nunez, EA; Vallette, G; Wähälä, K1
Adlercreutz, H; Bannwart, C; Brunow, G; Fotsis, T; Hase, T; Mäkelä, T; Musey, PI; Wähälä, K1
Calaf, G; Jordan, VC; Koch, R; Murphy, CS; Welshons, WV1
Adlercreutz, H; Dwyer, JT; Fotsis, T; Goldin, BR; Gorbach, SL; Heikkinen, R; Woods, M1
Campbell, DR; Kirkman, LM; Lampe, JW; Martini, MC; Slavin, JL1
Hutchins, AM; Lampe, JW; Slavin, JL1
Campbell, DR; Hutchins, AM; Lampe, JW; Martini, MC; Slavin, JL1
Griffiths, K; Morton, MS; Wahlqvist, ML; Wilcox, G1
Abranches-Monteiro, L; Blacklock, N; Chan, PS; Cheng, C; Correia, R; Griffiths, K; Lloyd, S; Matos-Ferreira, A; Morton, MS1
Adlercreutz, H; Akhmedkhanov, A; Toniolo, P; Zeleniuch-Jacquotte, A1
Bingham, SA; Botting, NP; Fryatt, T; Grace, PB; Oldfield, MF; Taylor, JI1
Andre, F; Antignac, JP; Cariou, R; Cravedi, JP; Le Bizec, B1
Campbell, MJ; Denholm, EE; Honour, JW; Leathem, AJ; Morton, MS; Newton, L; Woodside, JV; Young, IS1
Bolca, S; Bracke, M; De Keukeleire, D; Depypere, H; Heyerick, A; Possemiers, S; Verstraete, W; Wyns, C1
Hori, S; Nakagawa, H; Sugahara, T; Tamura, M; Yamauchi, S1
Chen, Y; Yang, F1

Trials

3 trial(s) available for 2,3-bis(3'-hydroxybenzyl)butane-1,4-diol and equol

ArticleYear
Urinary lignan and isoflavonoid excretion in men and women consuming vegetable and soy diets.
    Nutrition and cancer, 1995, Volume: 24, Issue:1

    Topics: 4-Butyrolactone; Adult; Chromans; Colon; Cross-Over Studies; Diet; Equol; Female; Gas Chromatography-Mass Spectrometry; Genistein; Glycine max; Humans; Isoflavones; Lignans; Male; Sex Characteristics; Vegetables

1995
Urinary isoflavonoid phytoestrogen and lignan excretion after consumption of fermented and unfermented soy products.
    Journal of the American Dietetic Association, 1995, Volume: 95, Issue:5

    Topics: 4-Butyrolactone; Adult; Chromans; Cross-Over Studies; Defecation; Diet; Equol; Estrogens; Estrogens, Non-Steroidal; Fermentation; Food Handling; Genistein; Glycine max; Humans; Isoflavones; Lignans; Male; Phytoestrogens; Plant Preparations; Taste

1995
Vegetables, fruits, and legumes: effect on urinary isoflavonoid phytoestrogen and lignan excretion.
    Journal of the American Dietetic Association, 1995, Volume: 95, Issue:7

    Topics: Adult; Chromans; Cross-Over Studies; Diet; Dietary Carbohydrates; Dietary Fats; Dietary Fiber; Energy Intake; Equol; Estrogens, Non-Steroidal; Fabaceae; Female; Flavonoids; Fruit; Genistein; Humans; Isoflavones; Lignans; Male; Phytoestrogens; Plant Preparations; Plants, Medicinal; Vegetables

1995

Other Studies

14 other study(ies) available for 2,3-bis(3'-hydroxybenzyl)butane-1,4-diol and equol

ArticleYear
Isotope dilution gas chromatographic-mass spectrometric method for the determination of lignans and isoflavonoids in human urine, including identification of genistein.
    Clinica chimica acta; international journal of clinical chemistry, 1991, Jul-15, Volume: 199, Issue:3

    Topics: 4-Butyrolactone; Butylene Glycols; Chromans; Equol; Female; Furans; Gas Chromatography-Mass Spectrometry; Genistein; Humans; Indicator Dilution Techniques; Isoflavones; Lignans; Lignin; Magnetic Resonance Spectroscopy; Male

1991
Phytoestrogens: new ligands for rat and human alpha-fetoprotein.
    Biochimica et biophysica acta, 1991, Sep-24, Volume: 1094, Issue:3

    Topics: 4-Butyrolactone; Adult; alpha-Fetoproteins; Animals; Arachidonic Acid; Binding, Competitive; Butylene Glycols; Chromans; Equol; Estrogens; Estrogens, Non-Steroidal; Humans; Immunoelectrophoresis; Isoflavones; Ligands; Lignans; Masoprocol; Phytoestrogens; Plant Preparations; Rats; Rats, Inbred Strains

1991
Identification of lignans and phytoestrogens in urine of chimpanzees.
    Clinica chimica acta; international journal of clinical chemistry, 1986, Jul-30, Volume: 158, Issue:2

    Topics: 4-Butyrolactone; Animals; Butylene Glycols; Chromans; Diet; Equol; Estrogens; Estrogens, Non-Steroidal; Isoflavones; Lignans; Male; Pan troglodytes; Phytoestrogens; Plant Extracts; Plant Preparations

1986
Stimulation of breast cancer cells in vitro by the environmental estrogen enterolactone and the phytoestrogen equol.
    Breast cancer research and treatment, 1987, Volume: 10, Issue:2

    Topics: 4-Butyrolactone; Benzopyrans; Breast Neoplasms; Butylene Glycols; Cell Division; Chromans; Equol; Estrogens; Female; Furans; Humans; Isoflavones; Lignans; Receptors, Progesterone; Tumor Cells, Cultured

1987
Excretion of the lignans enterolactone and enterodiol and of equol in omnivorous and vegetarian postmenopausal women and in women with breast cancer.
    Lancet (London, England), 1982, Dec-11, Volume: 2, Issue:8311

    Topics: 4-Butyrolactone; Aged; Benzopyrans; Breast Neoplasms; Butylene Glycols; Chromans; Diet; Diet, Vegetarian; Dietary Fiber; Energy Intake; Equol; Female; Furans; Humans; Isoflavones; Lignans; Menopause; Menstruation; Middle Aged; Plant Extracts

1982
Determination of lignans and isoflavonoids in human female plasma following dietary supplementation.
    The Journal of endocrinology, 1994, Volume: 142, Issue:2

    Topics: 4-Butyrolactone; Australia; Chromans; Diet; Equol; Estrogens; Female; Food, Fortified; Gas Chromatography-Mass Spectrometry; Genistein; Glycine max; Humans; Isoflavones; Lignans; Linseed Oil; Middle Aged; Monoamine Oxidase Inhibitors; Neoplasms; Plants, Edible; Postmenopause

1994
Lignans and isoflavonoids in plasma and prostatic fluid in men: samples from Portugal, Hong Kong, and the United Kingdom.
    The Prostate, 1997, Jul-01, Volume: 32, Issue:2

    Topics: 4-Butyrolactone; Adult; Aged; Chromans; Equol; Gas Chromatography-Mass Spectrometry; Hong Kong; Humans; Isoflavones; Lignans; Male; Middle Aged; Portugal; Prostate; Semen; United Kingdom

1997
Reliability of serum measurements of lignans and isoflavonoid phytoestrogens over a two-year period.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 1998, Volume: 7, Issue:10

    Topics: 4-Butyrolactone; Adult; Age Factors; Aged; Bias; Breast Neoplasms; Chromans; Equol; Feasibility Studies; Female; Genistein; Humans; Isoflavones; Lignans; Middle Aged; New York City; Pilot Projects; Postmenopause; Premenopause; Reference Values; Reproducibility of Results; Sensitivity and Specificity; Time Factors

1998
Quantification of isoflavones and lignans in urine using gas chromatography/mass spectrometry.
    Analytical biochemistry, 2003, Apr-01, Volume: 315, Issue:1

    Topics: 4-Butyrolactone; Equol; Female; Gas Chromatography-Mass Spectrometry; Genistein; Humans; Isoflavones; Lignans; Molecular Structure; Phytoestrogens; Plant Preparations; Reproducibility of Results; Sensitivity and Specificity

2003
Identification of phytoestrogens in bovine milk using liquid chromatography/electrospray tandem mass spectrometry.
    Rapid communications in mass spectrometry : RCM, 2003, Volume: 17, Issue:12

    Topics: 4-Butyrolactone; Animals; Cattle; Chromans; Chromatography, Liquid; Coumestrol; Equol; Estrogens, Non-Steroidal; Genistein; Ions; Isoflavones; Lignans; Milk; Molecular Structure; Phytoestrogens; Plant Preparations; Spectrometry, Mass, Electrospray Ionization

2003
Short-term phytoestrogen supplementation alters insulin-like growth factor profile but not lipid or antioxidant status.
    The Journal of nutritional biochemistry, 2006, Volume: 17, Issue:3

    Topics: Adult; Antioxidants; Diet; DNA Damage; Equol; Female; Flax; Genistein; Glycine max; Humans; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor I; Isoflavones; Kinetics; Lignans; Lipids; Middle Aged; Phytoestrogens

2006
Cosupplementation of isoflavones, prenylflavonoids, and lignans alters human exposure to phytoestrogen-derived 17beta-estradiol equivalents.
    The Journal of nutrition, 2009, Volume: 139, Issue:12

    Topics: Dietary Supplements; Equol; Estradiol; Feces; Flavanones; Flavonoids; Genistein; Humans; Isoflavones; Lignans; Phytoestrogens

2009
Effects of an equol-producing bacterium isolated from human faeces on isoflavone and lignan metabolism in mice.
    Journal of the science of food and agriculture, 2016, Volume: 96, Issue:9

    Topics: 4-Butyrolactone; Actinobacteria; Animals; Equol; Feces; Female; Gastrointestinal Microbiome; Humans; Isoflavones; Lignans; Lipids; Mice; Mice, Inbred ICR; Phytoestrogens

2016
Urinary phytoestrogens and the risk of uterine leiomyomata in US women.
    BMC women's health, 2023, 05-13, Volume: 23, Issue:1

    Topics: Bayes Theorem; Cross-Sectional Studies; Equol; Female; Genistein; Humans; Leiomyoma; Nutrition Surveys; Phytoestrogens

2023