2,3,7,8-tetrachlorodibenzofuran has been researched along with benzofurans in 105 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 29 (27.62) | 18.7374 |
| 1990's | 28 (26.67) | 18.2507 |
| 2000's | 15 (14.29) | 29.6817 |
| 2010's | 28 (26.67) | 24.3611 |
| 2020's | 5 (4.76) | 2.80 |
| Authors | Studies |
|---|---|
| Faith, RE; Lawson, LD; Luster, MI | 1 |
| Berghard, A; Gradin, K; Toftgård, R | 2 |
| Biegel, L; Liu, H; Narasimhan, TR; Rowlands, C; Safe, S | 1 |
| Lockhart, WL; Metner, DA; Muir, DC; Yarechewski, AL | 1 |
| Hahn, ME; Smolowitz, RM; Stegeman, JJ | 1 |
| Hollenback, CE; Perdew, GH | 1 |
| Bresnick, E; Xu, LC | 1 |
| Fernandez, N; Lesca, P; Souès, S; Souverain, P | 1 |
| Piskorska-Pliszczynska, J; Safe, S | 1 |
| Banks, YB; Birnbaum, LS; Brewster, DW; Clark, AM | 1 |
| Hällström, I | 1 |
| McNulty, WP | 1 |
| Birnbaum, LS; Brewster, DW | 1 |
| Luster, MI; Tucker, AN; Vore, SJ | 1 |
| Doyle, CP; Eschenroeder, A; Jaeger, RJ; Ospital, JJ | 1 |
| Bresnick, E; Houser, WH; Zielinski, R | 1 |
| Peterson, RG | 1 |
| Aldous, KM; Donnelly, RJ; Hilker, DR; Long, D; O'Keefe, PW; Pope, DH; Smith, RM | 1 |
| Birnbaum, LS; Harris, MW; Haseman, JK; Weber, H | 1 |
| Haraguchi, K; Kuroki, H; Masuda, Y; Yoshihara, S; Yoshimura, H | 1 |
| Birnbaum, LS; Weber, H | 1 |
| Crane, D; Frenkel, GD; Gierthy, JF | 1 |
| Birnbaum, LS; Collins, JM; Dedrick, RL; King, FG; Matthews, HB | 1 |
| Johnson, JL; Smith, LM; Stalling, DL | 1 |
| Jori, A | 1 |
| Borwell, P; d'Argy, R; Dencker, L; Hassoun, E; Lundin, LG | 1 |
| d'Argy, R; Dencker, L; Hassoun, E | 1 |
| Harris, MW; Lamb, JC; Moore, JA; Weber, H | 1 |
| Albro, PW; Chae, K; Corbett, JT; Lawson, LD; Luster, MI; McKinney, JD | 1 |
| Farrell, T; McNulty, WP; Pomerantz, I | 1 |
| Birnbaum, LS; Decad, GM; Matthews, HB; McConnell, EE | 1 |
| Birnbaum, LS; Decad, GM; Matthews, HB | 3 |
| Stevens, KM | 1 |
| Ramos, KS; Zhao, W | 1 |
| Birnbaum, LS; DeVito, MJ | 1 |
| Chaloupka, K; Gelboin, HV; Goldfarb, IS; Krishnan, V; Liu, G; Myers, MJ; Safe, S; Santostefano, M; Tsyrolv, IB | 1 |
| Hahn, ME; Stegeman, JJ | 1 |
| Gigliotti, PJ; Kumar, S; McGarrigle, BP; McReynolds, JH; Olson, JR | 1 |
| Belton, TJ; Hauge, PM; Lockwood, K; Mueller, RT; Ruppel, BE | 1 |
| Alworth, WL; Eugster, HP; Goldstein, JA; McReynolds, JH; Olson, JR; Sengstag, C; Tai, HL | 1 |
| Birnbaum, LS; Kedderis, LB; McKinley, MK | 1 |
| Bergman, A; Brandt, I; Darnerud, PO; Törnwall, U | 1 |
| Berghard, A; Gradin, K; Poellinger, L; Wilhelmsson, A | 1 |
| Liu, H; Safe, S | 1 |
| Kumar, S; Maslanka, R; Pangrekar, J; Sikka, HC; Steward, AR | 1 |
| Kumar, S; Maslanka, R; Sikka, HC; Steward, AR; Stuart, KG | 1 |
| Kiefer, F; Wegenke, M; Wiebel, FJ | 1 |
| Hagenmaier, H; Schmitz, HJ; Schrenk, D; Weber, R | 1 |
| Bastien, LJ; Hahn, ME; Kennedy, SW; Lorenzen, A | 1 |
| Bosveld, AT; Kennedy, SW; Seinen, W; van den Berg, M | 1 |
| Cidambi, K; Frank, MJ; Haas, CN; Kersten, SP; Wright, K | 1 |
| Hooper, K; McKinney, M; Petreas, MX; She, J; Stephens, RD; Sy, FJ; Visita, P; Winkler, JJ | 1 |
| Hossain, A; Ikawa, S; Kaji, M; Kikuchi, H; Konno, T; Minegishi, M; Osada, M; Tezuka, FA; Tsuchiya, S; Watanabe, M | 1 |
| Greenlee, WF; Hushka, LJ; Williams, JS | 1 |
| Paasivirta, J; Sinkkonen, S | 1 |
| Brauze, D; Malejka-Giganti, D | 1 |
| Hahn, ME; Hestermann, EV; Stegeman, JJ | 1 |
| Bello, SM; Franks, DG; Hahn, ME; Stegeman, JJ | 1 |
| McGovern, DG; McKinney, R; Norton, SB; Pruell, RJ; Taplin, BK | 1 |
| Nakanishi, J; Yoshida, K | 1 |
| Guella, G; Mancini, I; Perazzolli, C | 1 |
| Boverhof, DR; Budinsky, RA; Burgoon, LD; Dere, E; N'Jai, A; Rowlands, JC; Stebbins, KE; Tan, YS; Zacharewski, TR | 1 |
| Iwata, H; Kim, EY; Kubota, A | 1 |
| Aylward, LL; Budinsky, RA; Bursian, S; Giesy, JP; Kay, DP; Khim, JS; Moore, J; Rowlands, C; Shotwell, M; Woodburn, K; Zwiernik, MJ | 1 |
| Bursian, SJ; Giesy, JP; Hecker, M; Jones, PD; Moore, JN; Newsted, JL; Zhang, X; Zwiernik, MJ | 1 |
| Beckett, KJ; Bursian, S; Giesy, JP; Holem, RR; Kay, DP; Moore, JN; Yamini, B; Zwiernik, MJ | 1 |
| Imasaka, T; Kira, F; Miyoshi, Y; Uchimura, T; Watanabe-Ezoe, Y; Yamaguchi, S; Zaitsu, S | 1 |
| Eide, I; Olsvik, PA; Søfteland, L | 1 |
| Budinsky, RA; Burg, AR; Burgoon, LD; Dere, E; Ding, Q; N'jai, A; Rowlands, JC; Stebbins, KE; Zacharewski, TR | 1 |
| Bursian, SJ; Crump, D; Giesy, JP; Hervé, JC; Jones, PD; Jones, SP; Kennedy, SW; Mundy, LJ; Wan, Y; Wiseman, SB; Zwiernik, MJ | 1 |
| Bursian, SJ; Crump, D; Giesy, JP; Hervé, JC; Kennedy, SW; Zwiernik, MJ | 1 |
| Budinsky, RA; Burg, AR; Burgoon, LD; Harkema, JR; Ibrahim-Aibo, D; Kopec, AK; Lee, AW; Potter, D; Rowlands, JC; Sharratt, B; Tashiro, C; Zacharewski, TR | 1 |
| Budinsky, RA; Ferguson, SS; LeCluyse, EL; Rowlands, JC; Simon, T | 1 |
| Hahn, ME; Jensen, BA; Nelson, RK; Reddy, CM | 1 |
| Adriaens, P; Chen, Q; Demond, A; Franzblau, A; Garabrant, DH; Gillespie, BW; Hedgeman, E; Hong, B; Jolliet, O; Knutson, K; Lepkowski, J; Towey, T | 1 |
| Bursian, SJ; Cohen-Barnhouse, AM; Collins, B; Fitzgerald, SD; Giesy, JP; Hervé, JC; Jones, PD; Kay, D; Kennedy, SW; Link, JE; Newsted, JL; Wan, Y; Wiseman, S; Yang, Y; Zwiernik, MJ | 1 |
| Barone, G; Marcotrigiano, GO; Storelli, A; Storelli, MM | 1 |
| Batoev, VB; Iwata, H; Kim, EY; Petrov, EA; Suda, T; Tanabe, S | 1 |
| Bursian, SJ; Cohen-Barnhouse, AM; Fitzgerald, SD; Giesy, JP; Jones, PD; Kay, D; Kennedy, SW; Link, JE; Newsted, JL; Wiseman, S; Zwiernik, MJ | 1 |
| Fernández-Salguero, PM; Merino, JM; Sánchez-Martín, FJ | 1 |
| Celius, T; Matthews, J; Powis, M | 1 |
| Abdelmegeed, M; Budinsky, R; Cukovic, D; Dombkowski, A; Gollapudi, B; Novak, R; Rowlands, JC | 1 |
| Bradley, PW; Budinsky, R; Bursian, SJ; Fitzgerald, SD; Giesy, JP; Kay, D; Link, JE; Moore, JN; Newsted, JL; Zwiernik, MJ | 1 |
| Bai, J; Gong, C; Sun, X; Zhang, C; Zhao, Y | 1 |
| Bello, N; Bhat, VS; Budinsky, RA; Bursian, SJ; Fitzgerald, SD; Giesy, JP; Kay, D; Link, JE; Moore, J; Newsted, JL; Wiseman, S; Zhang, X; Zwiernik, MJ | 1 |
| Li, PZ; Tian, YJ; Wei, WX; Wu, GL; Yu, LF; Zhao, D | 1 |
| Crump, D; Farmahin, R; Jones, SP; Kennedy, SW; Mundy, LJ | 1 |
| Bonsack, P; Czerwinski, J; Emmenegger, L; Haag, R; Heeb, NV; Honegger, P; Kasper, M; Mayer, A; Schmid, P; Seiler, C; Ulrich, A; Wichser, A; Zennegg, M; Zeyer, K; Zimmerli, Y | 1 |
| Li, G; Li, Y; Liang, T; Ren, D; Wang, P; Xiao, K; Zhang, H; Zhang, Q | 1 |
| Albert, I; Correll, J; Gonzalez, FJ; Hatzakis, E; Hubbard, TD; Murray, IA; Nichols, RG; Patterson, AD; Perdew, GH; Sebastian, A; Smith, PB; Tanaka, N; Zhang, L | 1 |
| Chiaro, CR; Correll, J; Hao, R; Hatzakis, E; Nichols, RG; Patterson, AD; Perdew, GH; Smith, PB; Zhang, L | 1 |
| Giesy, JP; Li, J; Peng, Y; Wei, F; Xia, P; Zhang, R; Zhang, X | 1 |
| Chang, JW; Chen, HL; Lee, CC; Su, HJ | 1 |
| Andrade, VF; Cassimiro, DL; de Pinho, GP; Durães, AF; Silvério, FO | 1 |
| Saçan, MT; Şahin, AD | 1 |
| Abd El-Maguid, DS; El-Amir, YO; Elsharkawy, EE; Yahia, D | 1 |
| Feng, W; Li, P; Wang, W | 1 |
| Chen, G; Cheng, L; Dong, M; Lei, H; Ma, J; Song, Y; Xu, G; Yuan, P; Zhang, L | 1 |
| Budinsky, RA; Johnson, KJ; Lin, H; Passage, J; Sriram, S | 1 |
| Cai, J; Gui, W; Koo, I; Liu, Q; Nichols, RG; Patterson, AD; Rimal, B; Smith, PB; Tian, Y | 1 |
| Allman, EL; Anitha, M; Gui, W; Hao, F; Hubbard, TD; Liu, Q; Murray, IA; Nichols, RG; Patterson, AD; Perdew, GH; Smith, PB; Tian, Y; Zhang, L | 1 |
| Kakeyama, M; Kimura, E; Maekawa, F; Suzuki, G; Uramaru, N | 1 |
2 review(s) available for 2,3,7,8-tetrachlorodibenzofuran and benzofurans
| Article | Year |
|---|---|
Toxicity and fetotoxicity of TCDD, TCDF and PCB isomers in rhesus macaques (Macaca mulatta).
Topics: Abortion, Spontaneous; Acne Vulgaris; Animals; Benzofurans; Cell Differentiation; Dioxins; Epithelium; Female; Fetus; Gastric Mucosa; Isomerism; Macaca mulatta; Male; Nails; Polychlorinated Biphenyls; Polychlorinated Dibenzodioxins; Pregnancy; Structure-Activity Relationship | 1985 |
[Polychlorinated dibenzofurans (PCDF): environmental and toxicological aspects].
Topics: Animals; Benzofurans; Carcinogens; Chlorophenols; Dibenzofurans, Polychlorinated; Environmental Pollutants; Food Contamination; Guinea Pigs; Herbicides; Hexachlorobenzene; Humans; Mice; Oils; Polychlorinated Biphenyls; Rats; Teratogens; Tissue Distribution | 1984 |
103 other study(ies) available for 2,3,7,8-tetrachlorodibenzofuran and benzofurans
| Article | Year |
|---|---|
Effects of 2,3,7,8-tetrachlorodibenzofuran (TCDF) on the immune system in guinea pigs.
Topics: Animals; Antibody Formation; Benzofurans; Blood Proteins; Cell Division; Female; Guinea Pigs; Hydrocortisone; Immunity; Immunity, Cellular; Leukocyte Count; Lymphocytes; Organ Size; Thymidine; Time Factors | 1979 |
The stability of dioxin-receptor ligands influences cytochrome P450IA1 expression in human keratinocytes.
Topics: Base Sequence; Benzoflavones; Benzofurans; beta-Naphthoflavone; Cytochrome P-450 Enzyme System; Humans; Keratinocytes; Molecular Sequence Data; Polychlorinated Dibenzodioxins; Receptors, Aryl Hydrocarbon; Receptors, Drug; RNA, Messenger | 1992 |
Inhibition of insulin-like growth factor-I responses in MCF-7 cells by 2,3,7,8-tetrachlorodibenzo-p-dioxin and related compounds.
Topics: Benzofurans; Breast Neoplasms; Cell Division; Estradiol; Humans; Insulin-Like Growth Factor I; Polychlorinated Dibenzodioxins; Receptor, IGF Type 1; Receptors, Aryl Hydrocarbon; Receptors, Drug; Tumor Cells, Cultured | 1992 |
Dietary 2,3,7,8-tetrachlorodibenzofuran in rainbow trout: accumulation, disposition, and hepatic mixed-function oxidase enzyme induction.
Topics: Animals; Benzofurans; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Diet; Dose-Response Relationship, Drug; Enzyme Induction; Injections, Intraperitoneal; Liver; Mixed Function Oxygenases; Organ Size; Oxidoreductases; RNA, Messenger; Tissue Distribution; Trout | 1992 |
Immunohistochemical localization of environmentally induced cytochrome P450IA1 in multiple organs of the marine teleost Stenotomus chrysops (Scup).
Topics: Animals; Benzofurans; Cytochrome P-450 Enzyme System; Dibenzofurans, Polychlorinated; Environmental Exposure; Enzyme Induction; Fishes; Immunohistochemistry; Liver; Microsomes, Liver; Polychlorinated Biphenyls; Polycyclic Compounds; Tissue Distribution; Water Pollutants, Chemical | 1991 |
Analysis of photoaffinity-labeled aryl hydrocarbon receptor heterogeneity by two-dimensional gel electrophoresis.
Topics: Affinity Labels; Animals; Benzofurans; Cytoplasm; DNA; Electrophoresis, Polyacrylamide Gel; Humans; Isoelectric Focusing; Liver Neoplasms, Experimental; Molecular Weight; Neoplasm Proteins; Polychlorinated Dibenzodioxins; Rats; Rats, Inbred BUF; Receptors, Aryl Hydrocarbon; Receptors, Drug; Species Specificity; Thymus Gland; Tumor Cells, Cultured | 1990 |
Induction of cytochrome P450IA1 in rat hepatoma cell by polycyclic hydrocarbons and a dioxin.
Topics: Animals; Benzo(a)pyrene; Benzofurans; Cytochrome P-450 Enzyme System; Dioxins; Enzyme Induction; Gene Expression Regulation, Enzymologic; Isoenzymes; Liver Neoplasms, Experimental; Methylcholanthrene; Polychlorinated Dibenzodioxins; Rats; Tumor Cells, Cultured | 1990 |
Intracellular lipoproteins as carriers for 2,3,7,8-tetrachlorodibenzo-p-dioxin and benzo(a)pyrene in rat and mouse liver.
Topics: Animals; Benzo(a)pyrene; Benzofurans; Carrier Proteins; Dioxins; In Vitro Techniques; Lipoproteins; Liver; Mice; Mice, Inbred C57BL; Polychlorinated Dibenzodioxins; Rats; Rats, Inbred Strains; Receptors, Aryl Hydrocarbon; Receptors, Drug | 1989 |
Radioligand-dependent differences in the molecular properties of the mouse and rat hepatic aryl hydrocarbon receptor complexes.
Topics: Animals; Benzofurans; Centrifugation, Density Gradient; Chromatography, Gel; Cytosol; Female; Humans; Liver; Male; Mice; Mice, Inbred C57BL; Polychlorinated Dibenzodioxins; Rats; Receptors, Aryl Hydrocarbon; Receptors, Drug; Species Specificity | 1988 |
Comparative dermal absorption of 2,3,7,8-tetrachlorodibenzo-p-dioxin and three polychlorinated dibenzofurans.
Topics: Administration, Cutaneous; Animals; Benzofurans; Dioxins; Dose-Response Relationship, Drug; Environmental Pollutants; Feces; Industrial Waste; Male; Polychlorinated Dibenzodioxins; Polymers; Rats; Rats, Inbred F344; Skin Absorption; Tissue Distribution | 1989 |
Effects of pretreatment with 2,3,7,8-tetrachlorodibenzofuran on microsomal monooxygenase activity in Drosophila melanogaster.
Topics: Animals; Benzofurans; Cell Fractionation; Drosophila melanogaster; Environmental Pollutants; Kinetics; Microsomes; Mixed Function Oxygenases | 1986 |
Disposition of 1,2,3,7,8-pentachlorodibenzofuran in the rat.
Topics: Animals; Benzofurans; Bile; Environmental Pollutants; Feces; Lethal Dose 50; Male; Rats; Rats, Inbred F344; Structure-Activity Relationship; Tissue Distribution | 1988 |
Suppression of B cell differentiation by 2,3,7,8-tetrachlorodibenzo-p-dioxin.
Topics: Animals; Antibody Formation; B-Lymphocytes; Benzofurans; Cell Differentiation; Dioxins; Female; Malaria; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Polychlorinated Dibenzodioxins; Structure-Activity Relationship; Thymectomy | 1986 |
Health risk analysis of human exposures to soil amended with sewage sludge contaminated with polychlorinated dibenzodioxins and dibenzofurans.
Topics: Adult; Benzofurans; Child; Dioxins; Health; Humans; Polychlorinated Dibenzodioxins; Risk; Sewage; Skin Absorption; Soil Pollutants | 1986 |
Further characterization of the polycyclic aromatic hydrocarbon binding properties of the 4S protein.
Topics: Age Factors; Animals; Benzo(a)pyrene; Benzofurans; Binding, Competitive; Carrier Proteins; Cytosol; Enzyme Induction; Female; Liver; Macromolecular Substances; Male; Molybdenum; Phenobarbital; Polycyclic Compounds; Rats; Safrole | 1986 |
C15-C18 isomers synthesized from [13C]-2,3,7,8-tetrachlorodibenzofuran via surface chlorination.
Topics: Benzofurans; Chemical Phenomena; Chemistry; Chlorine; Chromatography, Gas; Isomerism | 1987 |
Nonaccumulation of chlorinated dioxins and furans by goldfish exposed to contaminated sediment and flyash.
Topics: Animals; Benzofurans; Biological Availability; Carbon; Coal Ash; Cyprinidae; Dioxins; Furans; Goldfish; Mass Spectrometry; Particulate Matter; Polychlorinated Dibenzodioxins; Stereoisomerism; Water Pollutants; Water Pollutants, Chemical | 1986 |
Teratogenic potency of TCDD, TCDF and TCDD-TCDF combinations in C57BL/6N mice.
Topics: Animals; Benzofurans; Body Weight; Cleft Palate; Dioxins; Dose-Response Relationship, Drug; Drug Interactions; Female; Hydronephrosis; Liver; Mice; Mice, Inbred C57BL; Organ Size; Polychlorinated Dibenzodioxins; Pregnancy; Teratogens | 1985 |
[Effects of impurities on enzyme induction and toxicity in rats treated with 2,3,7,8-tetrachlorodibenzofuran].
Topics: Animals; Benzofurans; Enzyme Induction; Male; Microsomes, Liver; Rats; Rats, Inbred Strains | 1985 |
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) and 2,3,7,8-tetrachlorodibenzofuran (TCDF) in pregnant C57BL/6N mice: distribution to the embryo and excretion.
Topics: Animals; Benzofurans; Cleft Palate; Dioxins; Embryo, Mammalian; Female; Gestational Age; Maternal-Fetal Exchange; Mice; Mice, Inbred C57BL; Polychlorinated Dibenzodioxins; Pregnancy; Teratogens; Tissue Distribution | 1985 |
Application of an in vitro keratinization assay to extracts of soot from a fire in a polychlorinated biphenyl-containing transformer.
Topics: Air Pollutants; Benzofurans; Carbon; Cell Line; Humans; Keratins; Polychlorinated Biphenyls; Polychlorinated Dibenzodioxins | 1984 |
Physiological model for the pharmacokinetics of 2,3,7,8-tetrachlorodibenzofuran in several species.
Topics: Animals; Benzofurans; Environmental Pollutants; Haplorhini; Kinetics; Liver; Metabolic Clearance Rate; Mice; Mice, Inbred Strains; Models, Biological; Rats; Species Specificity | 1983 |
Determination of part-per-trillion levels of polychlorinated dibenzofurans and dioxins in environmental samples.
Topics: Animals; Benzofurans; Birds; Dioxins; Environmental Pollutants; Polychlorinated Biphenyls; Salmon; Soil Pollutants | 1984 |
Teratogenicity of 2,3,7,8-tetrachlorodibenzofuran in BXD recombinant inbred strains.
Topics: Abnormalities, Drug-Induced; Animals; Benzofurans; Chromosome Mapping; Cleft Palate; Female; Fetal Resorption; Hydronephrosis; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Inbred Strains; Polychlorinated Dibenzodioxins; Pregnancy | 1984 |
Teratogenicity of 2,3,7,8-tetrachlorodibenzofuran in the mouse.
Topics: Abnormalities, Drug-Induced; Animals; Benzofurans; Dose-Response Relationship, Drug; Environmental Pollutants; Female; Fetus; Mice; Mice, Inbred C57BL; Ornithine Decarboxylase; Polychlorinated Dibenzodioxins; Pregnancy | 1984 |
Teratogenicity of 2.3.7.8-tetrachlorodibenzofuran (TCDF) in mice.
Topics: Abnormalities, Drug-Induced; Animals; Benzofurans; Cleft Palate; Female; Fetal Death; Gestational Age; Hydronephrosis; Maternal-Fetal Exchange; Mice; Mice, Inbred C57BL; Pregnancy; Teratogens | 1984 |
Radioimmunoassay for quantitation of 2,3,7,8-tetrachlorodibenzofuran.
Topics: Adipose Tissue; Animals; Aroclors; Benzofurans; Environmental Pollutants; Haplorhini; Liver; Radioimmunoassay; Rats | 1980 |
Chronic toxicity of 2,3,7,8-tetrachlorodibenzofuran for rhesus macaques.
Topics: Animals; Benzofurans; Environmental Pollutants; Gastric Mucosa; Macaca mulatta; Male; Polychlorinated Biphenyls; Polychlorinated Dibenzodioxins; Sebaceous Glands; Thymus Gland | 1981 |
Fate of 2,3,7,8-tetrachlorodibenzofuran in the monkey.
Topics: Animals; Benzofurans; Feces; Kinetics; Macaca mulatta; Tissue Distribution | 1981 |
2,3,7,8-Tetrachlorodibenzofuran tissue distribution and excretion in guinea pig.
Topics: Adipose Tissue; Administration, Oral; Aging; Animals; Benzofurans; Body Weight; Guinea Pigs; Injections, Intravenous; Liver; Male; Skin; Tissue Distribution | 1981 |
Distribution and excretion of 2,3,7,8-tetrachlorodibenzofuran in C57BL/6J and DBA/2J mice.
Topics: Animals; Benzofurans; Half-Life; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Species Specificity; Tissue Distribution | 1981 |
Agent Orange toxicity: a quantitative perspective.
Topics: 2,4-Dichlorophenoxyacetic Acid; 2,4,5-Trichlorophenoxyacetic Acid; Abnormalities, Drug-Induced; Agent Orange; Animals; Benzofurans; Dioxins; Environmental Pollutants; Female; Food Contamination; Herbicides; Humans; Male; Polychlorinated Dibenzodioxins; Pregnancy; Soil Pollutants; Vietnam | 1981 |
Disposition and excretion of 2,3,7,8-tetrachlorodibenzofuran in the rat.
Topics: Animals; Benzofurans; Bile; Biotransformation; Kinetics; Male; Rats; Tissue Distribution | 1980 |
Differential effects of a topoisomerase I inhibitor on dioxin inducibility and high-level expression of the cytochrome P450IA1 gene.
Topics: Adult; Base Sequence; Benzofurans; Blotting, Northern; Camptothecin; Cytochrome P-450 Enzyme System; DNA Topoisomerases, Type I; Enzyme Induction; Enzyme Inhibitors; Gene Expression; Gene Expression Regulation; Humans; Keratinocytes; Molecular Sequence Data; Polychlorinated Dibenzodioxins; Receptors, Aryl Hydrocarbon; RNA, Messenger; Topoisomerase I Inhibitors; Transfection | 1995 |
Inhibition of DNA synthesis in primary cultures of adult rat hepatocytes by benzo[a]pyrene and related aromatic hydrocarbons: role of Ah receptor-dependent events.
Topics: Analysis of Variance; Animals; Benzo(a)pyrene; Benzofurans; Cells, Cultured; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; DNA; Dose-Response Relationship, Drug; Female; Flow Cytometry; Hydrocarbons; L-Lactate Dehydrogenase; Liver; Oxidoreductases; Polychlorinated Dibenzodioxins; Rats; Rats, Sprague-Dawley; Receptors, Aryl Hydrocarbon | 1995 |
The importance of pharmacokinetics in determining the relative potency of 2,3,7,8-tetrachlorodibenzo-p-dioxin and 2,3,7,8-tetrachlorodibenzofuran.
Topics: Animals; Benzofurans; Body Weight; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Drug Administration Schedule; Enzyme Induction; Female; Half-Life; Mice; Mice, Inbred Strains; Organ Size; Oxidoreductases; Polychlorinated Dibenzodioxins; Sensitivity and Specificity; Skin | 1995 |
Aryl hydrocarbon (Ah) receptor-independent induction of Cyp1a2 gene expression by acenaphthylene and related compounds in B6C3F1 mice.
Topics: Acenaphthenes; Animals; Anthracenes; Antibodies, Monoclonal; Benzofurans; Crosses, Genetic; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Fluorenes; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Microsomes, Liver; Oxidoreductases; Perylene; Phenanthrenes; Polychlorinated Dibenzodioxins; Receptors, Aryl Hydrocarbon | 1994 |
Regulation of cytochrome P4501A1 in teleosts: sustained induction of CYP1A1 mRNA, protein, and catalytic activity by 2,3,7,8-tetrachlorodibenzofuran in the marine fish Stenotomus chrysops.
Topics: Animals; Benzofurans; Catalysis; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; DNA, Complementary; Dose-Response Relationship, Drug; Enzyme Induction; Female; Fishes; Isomerism; Male; Oxidoreductases; RNA, Messenger; Structure-Activity Relationship; Time Factors | 1994 |
Hepatic uptake and metabolism of 2,3,7,8-tetrachlorodibenzo-p-dioxin and 2,3,7,8-tetrachlorodibenzofuran.
Topics: Animals; Benzofurans; Cytochrome P-450 Enzyme System; Humans; In Vitro Techniques; Liver; Male; Microsomes, Liver; Polychlorinated Dibenzodioxins; Rats; Rats, Sprague-Dawley | 1994 |
2,3,7,8-TCDD and 2,3,7,8-TCDF in blue crabs and American lobsters from the Hudson-Raritan estuary and the New York Bight.
Topics: Animals; Benzofurans; Body Weight; Brachyura; Fisheries; Gas Chromatography-Mass Spectrometry; Liver; Marine Biology; Muscles; Nephropidae; New Jersey; New York; Pancreas; Polychlorinated Dibenzodioxins; Water Pollutants, Chemical | 1994 |
Cytochrome P4501A1 mediates the metabolism of 2,3,7,8-tetrachlorodibenzofuran in the rat and human.
Topics: Animals; Benzofurans; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Environmental Pollutants; Humans; Liver; Male; Oxidoreductases; Rats; Rats, Sprague-Dawley; Species Specificity | 1993 |
The effect of pretreatment on the biliary excretion of 2,3,7,8-tetrachlorodibenzo-p-dioxin, 2,3,7,8-tetrachlorodibenzofuran, and 3,3',4,4'-tetrachlorobiphenyl in the rat.
Topics: Animals; Aroclors; Benzofurans; Bile; Chlorodiphenyl (54% Chlorine); Enzyme Induction; Feces; Male; Polychlorinated Biphenyls; Polychlorinated Dibenzodioxins; Rats; Rats, Inbred F344 | 1993 |
Liver accumulation of 2,3,7,8-tetrachloro-[3H]dibenzofuran in mice: modulation by treatments with polychlorinated biphenyls.
Topics: Animals; Aroclors; Autoradiography; Benzofurans; Chlorodiphenyl (54% Chlorine); Chromatography, Gas; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Drug Interactions; Female; Liver; Mice; Oxidoreductases; Polychlorinated Biphenyls; Pregnancy; Tissue Distribution | 1993 |
Nonresponsiveness of normal human fibroblasts to dioxin correlates with the presence of a constitutive xenobiotic response element-binding factor.
Topics: Base Sequence; Benzofurans; Cells, Cultured; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Deoxyribonuclease I; DNA; Fibroblasts; Gene Expression Regulation, Enzymologic; Humans; Keratinocytes; Molecular Sequence Data; Oxidoreductases; Polychlorinated Dibenzodioxins; Receptors, Aryl Hydrocarbon; Receptors, Drug; Regulatory Sequences, Nucleic Acid; RNA, Messenger; Tumor Cells, Cultured | 1993 |
Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on insulin-induced responses in MCF-7 human breast cancer cells.
Topics: Base Sequence; Benzofurans; Breast Neoplasms; Carcinoma; Cell Division; Humans; Insulin Antagonists; Molecular Sequence Data; Polychlorinated Dibenzodioxins; Tumor Cells, Cultured | 1996 |
Disposition and metabolism of 2,3,7,8-tetrachlorodibenzofuran by rainbow trout (Oncorhynchus mykiss).
Topics: Animals; Benzofurans; Bile; Chromatography, High Pressure Liquid; Environmental Pollutants; Half-Life; Liver; Muscles; Oncorhynchus mykiss; Tissue Distribution | 1996 |
Disposition and metabolism of 2,3,7,8-tetrachlorodibenzofuran by channel catfish (Ictalurus punctatus).
Topics: Animals; Benzofurans; Bile; Environmental Pollutants; Half-Life; Ictaluridae; Liver; Tissue Distribution | 1996 |
Bioassay for determining 2,3,7,8-tetrachlorodibenzo-p-dioxin equivalents (TEs) in human hepatoma Hepg2 cells.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benz(a)Anthracenes; Benzofurans; Biological Assay; Carcinoma, Hepatocellular; Cytochrome P-450 CYP1A1; Environmental Pollutants; Humans; Liver Neoplasms; Polychlorinated Dibenzodioxins; Rats; Tumor Cells, Cultured | 1996 |
Metabolic degradation, inducing potency, and metabolites of fluorinated and chlorinated-fluorinated dibenzodioxins and dibenzofurans.
Topics: Animals; Benzofurans; Biotransformation; Cytochrome P-450 CYP1A1; Dioxins; Liver; Male; Mass Spectrometry; Mice; Polychlorinated Dibenzodioxins; Soil Pollutants; Structure-Activity Relationship | 1997 |
Halogenated aromatic hydrocarbon-mediated porphyrin accumulation and induction of cytochrome P4501A in chicken embryo hepatocytes.
Topics: Animals; Benzofurans; Cells, Cultured; Chick Embryo; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Enzyme Induction; Liver; Polychlorinated Biphenyls; Polychlorinated Dibenzodioxins; Porphyrins | 1997 |
Ethoxyresorufin-O-deethylase (EROD) inducing potencies of planar chlorinated aromatic hydrocarbons in primary cultures of hepatocytes from different developmental stages of the chicken.
Topics: Animals; Animals, Newborn; Benzofurans; Cells, Cultured; Chick Embryo; Chickens; Cytochrome P-450 CYP1A1; Enzyme Induction; Liver; Polychlorinated Biphenyls; Polychlorinated Dibenzodioxins | 1997 |
Generalization of independent response model for toxic mixtures.
Topics: Animals; Benzofurans; Cleft Palate; Data Interpretation, Statistical; Drug Antagonism; Drug Interactions; Drug Synergism; Drug-Related Side Effects and Adverse Reactions; Humans; Hydrocarbons, Chlorinated; Insecticides; Mice; Mice, Inbred C57BL; Models, Theoretical; Polychlorinated Dibenzodioxins | 1997 |
Congener-specific analysis of PCBs in human milk from Kazakhstan.
Topics: Benzofurans; Female; Gas Chromatography-Mass Spectrometry; Humans; Infant; Infant, Newborn; Kazakhstan; Milk, Human; Polychlorinated Biphenyls; Polychlorinated Dibenzodioxins; Soil Pollutants; World Health Organization | 1998 |
The Ah receptor is not involved in 2,3,7,8-tetrachlorodibenzo- p-dioxin-mediated apoptosis in human leukemic T cell lines.
Topics: Apoptosis; Aspartic Acid; Benzofurans; beta-Naphthoflavone; Calcium-Calmodulin-Dependent Protein Kinases; Cycloheximide; DNA Fragmentation; Environmental Pollutants; Enzyme Activation; Gene Expression Regulation, Neoplastic; Genistein; Humans; JNK Mitogen-Activated Protein Kinases; Lymphoma, T-Cell; Microscopy, Fluorescence; Mitogen-Activated Protein Kinases; Mutation; Polychlorinated Dibenzodioxins; Proto-Oncogene Proteins c-bcl-2; Receptors, Aryl Hydrocarbon; RNA, Messenger; Tumor Cells, Cultured | 1998 |
Characterization of 2,3,7,8-tetrachlorodibenzofuran-dependent suppression and AH receptor pathway gene expression in the developing mouse mammary gland.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzofurans; Cell Division; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; Cytochrome P-450 Enzyme System; DNA Replication; Epithelial Cells; Female; Gene Expression; Immunoenzyme Techniques; Mammary Glands, Animal; Mice; Mice, Inbred C57BL; Mice, Knockout; Organ Culture Techniques; Receptors, Aryl Hydrocarbon; RNA, Messenger; Signal Transduction | 1998 |
Polychlorinated organic compounds in the Arctic cod liver: trends and profiles.
Topics: Animals; Arctic Regions; Benzofurans; DDT; Environmental Monitoring; Fishes; Hexachlorocyclohexane; Hydrocarbons, Chlorinated; Liver; Longitudinal Studies; Pesticides; Polychlorinated Biphenyls | 2000 |
A novel 4 S [3H]beta-naphthoflavone-binding protein in liver cytosol of female Sprague-Dawley rats treated with aryl hydrocarbon receptor agonists.
Topics: Animals; Benzo(a)pyrene; Benzoflavones; Benzofurans; beta-Naphthoflavone; Binding, Competitive; Carrier Proteins; Cytochrome P-450 CYP1A1; Cytosol; Female; Glycine N-Methyltransferase; Kinetics; Liver; Methylcholanthrene; Methyltransferases; Molecular Weight; Polychlorinated Dibenzodioxins; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, Aryl Hydrocarbon | 2000 |
Relative contributions of affinity and intrinsic efficacy to aryl hydrocarbon receptor ligand potency.
Topics: Animals; Benzofurans; Binding, Competitive; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Environmental Pollutants; Enzyme Induction; Isoenzymes; Kinetics; Ligands; Polychlorinated Biphenyls; Polychlorinated Dibenzodioxins; Receptors, Aryl Hydrocarbon; Structure-Activity Relationship | 2000 |
Acquired resistance to Ah receptor agonists in a population of Atlantic killifish (Fundulus heteroclitus) inhabiting a marine superfund site: in vivo and in vitro studies on the inducibility of xenobiotic metabolizing enzymes.
Topics: Animals; Benzofurans; beta-Naphthoflavone; Body Weight; Cells, Cultured; Cytochrome P-450 CYP1A1; Drug Tolerance; Enzyme Induction; Female; Glucuronosyltransferase; Glutathione Transferase; Gonads; Hazardous Waste; Hepatocytes; Killifishes; Liver; Male; Microsomes; Organ Size; Polychlorinated Dibenzodioxins; Receptors, Aryl Hydrocarbon; RNA, Messenger | 2001 |
Organic contaminant distributions in sediments, polychaetes (Nereis virens) and American lobster (Homarus americanus) from a laboratory food chain experiment.
Topics: Animals; Benzofurans; Dibenzofurans, Polychlorinated; Food Chain; Geologic Sediments; Nephropidae; Polychaeta; Polychlorinated Biphenyls; Polychlorinated Dibenzodioxins; Soil Pollutants; Thiophenes | 2000 |
Estimation of dioxin risk to Japanese from the past to the future.
Topics: Adult; Benzofurans; Body Burden; Dibenzofurans, Polychlorinated; Dioxins; Environmental Exposure; Environmental Pollutants; Female; Humans; Incineration; Japan; Models, Theoretical; Polychlorinated Dibenzodioxins; Public Health; Reproduction; Risk Assessment; Safety; Soil Pollutants | 2003 |
Benzene-assisted atmospheric-pressure chemical ionization: a new liquid chromatography/mass spectrometry approach to the analysis of selected hydrophobic compounds.
Topics: Air Pollutants; Aldrin; Atmosphere; Benzene; Benzofurans; Chromatography, High Pressure Liquid; DDT; Dichlorodiphenyl Dichloroethylene; Dichlorodiphenyldichloroethane; Environmental Monitoring; Hydrophobic and Hydrophilic Interactions; Polychlorinated Dibenzodioxins; Spectrometry, Mass, Electrospray Ionization | 2005 |
Comparative temporal toxicogenomic analysis of TCDD- and TCDF-mediated hepatic effects in immature female C57BL/6 mice.
Topics: Administration, Oral; Animals; Benzofurans; Environmental Pollutants; Female; Gene Expression Profiling; Gene Expression Regulation; Hepatocytes; Liver; Mice; Mice, Inbred C57BL; Oligonucleotide Array Sequence Analysis; Polychlorinated Dibenzodioxins; RNA, Messenger; Time Factors; Toxicogenetics; Vacuoles | 2008 |
Catalytic function of avian cytochrome P450 1A4 and 1A5 (CYP1A4 and CYP1A5) enzymes heterologously expressed using in vitro yeast system.
Topics: Animals; Avian Proteins; Benzofurans; Birds; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Kinetics; Liver; Water Pollutants, Chemical; Yeasts | 2008 |
Toxicokinetics of 2,3,7,8-TCDF and 2,3,4,7,8-PeCDF in mink (Mustela vison) at ecologically relevant exposures.
Topics: Adipose Tissue; Animals; Benzofurans; Ecology; Female; Liver; Mink; Models, Biological | 2008 |
Sequencing and characterization of mixed function monooxygenase genes CYP1A1 and CYP1A2 of Mink (Mustela vison) to facilitate study of dioxin-like compounds.
Topics: Animals; Benzofurans; Blotting, Western; Cloning, Molecular; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Environmental Pollutants; Enzyme Induction; Female; Kinetics; Liver; Mink; Oxazines; Phylogeny; Receptors, Aryl Hydrocarbon; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Analysis, DNA; Sequence Analysis, Protein; Sequence Homology, Amino Acid; Substrate Specificity | 2009 |
Chronic effects of polychlorinated dibenzofurans on mink in laboratory and field environments.
Topics: Animals; Benzofurans; Dibenzofurans, Polychlorinated; Dose-Response Relationship, Drug; Ecosystem; Environmental Pollutants; Female; Male; Michigan; Mink; Population Dynamics; Time Factors | 2009 |
Near-ultraviolet femtosecond laser ionization of dioxins in gas chromatography/time-of-flight mass spectrometry.
Topics: Air Pollutants; Benzofurans; Dibenzofurans, Polychlorinated; Dioxins; Gas Chromatography-Mass Spectrometry; Lasers; Polychlorinated Dibenzodioxins; Sensitivity and Specificity; Spectrum Analysis, Raman; Temperature; Time Factors; Ultraviolet Rays | 2009 |
Factorial design applied for multiple endpoint toxicity evaluation in Atlantic salmon (Salmo salar L.) hepatocytes.
Topics: Animals; Benzofurans; Cells, Cultured; Cytochrome P-450 CYP1A1; Dose-Response Relationship, Drug; Endpoint Determination; Glucuronosyltransferase; Hepatocytes; Polychlorinated Biphenyls; Polychlorinated Dibenzodioxins; Principal Component Analysis; RNA, Messenger; Salmo salar | 2009 |
Automated dose-response analysis of the relative hepatic gene expression potency of TCDF in C57BL/6 mice.
Topics: Animals; Automation; Benzofurans; Body Weight; Dose-Response Relationship, Drug; Female; Gene Expression Profiling; Liver; Mice; Mice, Inbred C57BL; Organ Size; Polychlorinated Dibenzodioxins; Polymerase Chain Reaction | 2009 |
Cytochrome P4501A induction by 2,3,7,8-tetrachlorodibenzo-p-dioxin and two chlorinated dibenzofurans in primary hepatocyte cultures of three avian species.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzofurans; Birds; Cells, Cultured; Chickens; Coturnix; Cytochrome P-450 CYP1A1; Enzyme Induction; Galliformes; Hepatocytes; Polychlorinated Dibenzodioxins; RNA, Messenger | 2010 |
Ethoxyresorufin O-deethylase induction by TCDD, PeCDF and TCDF in ring-necked pheasant and Japanese quail hepatocytes: Time-dependent effects on concentration-response curves.
Topics: Animals; Benzofurans; Cells, Cultured; Coturnix; Cytochrome P-450 CYP1A1; Dose-Response Relationship, Drug; Enzyme Induction; Galliformes; Hepatocytes; Polychlorinated Dibenzodioxins | 2010 |
Automated dose-response analysis and comparative toxicogenomic evaluation of the hepatic effects elicited by TCDD, TCDF, and PCB126 in C57BL/6 mice.
Topics: Animals; Benzofurans; Cytochrome P-450 CYP1A1; Dose-Response Relationship, Drug; Environmental Pollutants; Female; Gene Expression; Ligands; Liver; Mice; Mice, Inbred C57BL; Oligonucleotide Array Sequence Analysis; Organ Size; Ovariectomy; Polychlorinated Biphenyls; Polychlorinated Dibenzodioxins; RNA, Messenger; Toxicogenetics | 2010 |
Human and rat primary hepatocyte CYP1A1 and 1A2 induction with 2,3,7,8-tetrachlorodibenzo-p-dioxin, 2,3,7,8-tetrachlorodibenzofuran, and 2,3,4,7,8-pentachlorodibenzofuran.
Topics: Animals; Benzofurans; Cells, Cultured; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Dose-Response Relationship, Drug; Environmental Pollutants; Enzyme Induction; Gene Expression Regulation, Enzymologic; Hepatocytes; Humans; No-Observed-Adverse-Effect Level; Polychlorinated Dibenzodioxins; Rats; Receptors, Aryl Hydrocarbon; Risk Assessment; Species Specificity | 2010 |
Developing tools for risk assessment in protected species: Relative potencies inferred from competitive binding of halogenated aromatic hydrocarbons to aryl hydrocarbon receptors from beluga (Delphinapterus leucas) and mouse.
Topics: Animals; Beluga Whale; Benzofurans; Binding, Competitive; Endangered Species; Environmental Pollutants; Hydrocarbons, Aromatic; Mice; Polychlorinated Biphenyls; Polychlorinated Dibenzodioxins; Receptors, Aryl Hydrocarbon; Risk Assessment | 2010 |
Case report: the University of Michigan dioxin exposure study: a follow-up investigation of a case with high serum concentration of 2,3,4,7,8-pentachlorodibenzofuran.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Benzofurans; Cattle; Humans; Michigan; Middle Aged; Soil Pollutants; Young Adult | 2010 |
Sensitivity of Japanese quail (Coturnix japonica), Common pheasant (Phasianus colchicus), and White Leghorn chicken (Gallus gallus domesticus) embryos to in ovo exposure to TCDD, PeCDF, and TCDF.
Topics: Animals; Benzofurans; Chick Embryo; Chickens; Coturnix; Embryo, Nonmammalian; Galliformes; Lethal Dose 50; Models, Biological; Ovum; Polychlorinated Dibenzodioxins; Species Specificity; Toxicity Tests | 2011 |
Levels and congener profiles of PCBs and PCDD/Fs in blue shark (Prionace glauca) liver from the South-Eastern Mediterranean Sea (Italy).
Topics: Animals; Benzofurans; Dibenzofurans, Polychlorinated; Environmental Monitoring; Italy; Liver; Mediterranean Sea; Polychlorinated Biphenyls; Polychlorinated Dibenzodioxins; Sharks; Water Pollutants, Chemical | 2011 |
Evaluation of relative potencies for in vitro transactivation of the baikal seal aryl hydrocarbon receptor by dioxin-like compounds.
Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Benzofurans; Chlorocebus aethiops; COS Cells; Cytochrome P-450 CYP1A1; Dioxins; Environmental Pollutants; Forecasting; Liver; Mice; Receptors, Aryl Hydrocarbon; Seals, Earless | 2011 |
Developmental and posthatch effects of in ovo exposure to 2,3,7,8-TCDD, 2,3,4,7,8-PECDF, and 2,3,7,8-TCDF in Japanese quail (Coturnix japonica), common pheasant (Phasianus colchicus), and white leghorn chicken (Gallus gallus domesticus) embryos.
Topics: Animals; Benzofurans; Body Size; Brain; Chick Embryo; Coturnix; Embryo, Nonmammalian; Embryonic Development; Enzyme Induction; Galliformes; Liver; Myocardium; Organ Size; Ovum; Polychlorinated Dibenzodioxins; Spleen | 2011 |
Aryl hydrocarbon receptor-dependent induction of apoptosis by 2,3,7,8-tetrachlorodibenzo-p-dioxin in cerebellar granule cells from mouse.
Topics: Animals; Apoptosis; Benzofurans; Caspase 3; Cells, Cultured; Cerebellum; Cytochrome P-450 CYP1A2; Dose-Response Relationship, Drug; Environmental Pollutants; Indoles; Mice; Mice, Knockout; Neurons; Reactive Oxygen Species; Receptors, Aryl Hydrocarbon; Tetrazolium Salts; Thiazoles; Trypan Blue | 2011 |
Differential ligand-dependent activation and a role for Y322 in aryl hydrocarbon receptor-mediated regulation of gene expression.
Topics: Aryl Hydrocarbon Hydroxylases; Basic Helix-Loop-Helix Transcription Factors; Benzofurans; Cell Line, Tumor; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; Gene Expression Regulation, Enzymologic; Humans; Ligands; Omeprazole; Polychlorinated Dibenzodioxins; Receptors, Aryl Hydrocarbon; Tyrosine | 2011 |
Transcriptional profiles induced by the Aryl Hydrocarbon Receptor agonists 2,3,7,8-tetrachlorodibenzo-p-dioxin, 2,3,7,8-tetrachlorodibenzofuran and 2,3,4,7,8-pentachlorodibenzofuran in primary rat hepatocytes.
Topics: Animals; Benzofurans; Female; Gene Expression Regulation; Hepatocytes; Multigene Family; Oligonucleotide Array Sequence Analysis; Polychlorinated Dibenzodioxins; Principal Component Analysis; Rats; Rats, Sprague-Dawley; Receptors, Aryl Hydrocarbon; RNA, Messenger | 2011 |
Effects of dietary exposure of mink (Mustela vison) to 2,3,7,8-tetrachlorodibenzo-p-dioxin, 2,3,4,7,8-pentachlorodibenzofuran, and 2,3,7,8-tetrachlorodibenzofuran on reproduction and offspring viability and growth.
Topics: Adult; Animals; Benzofurans; Diet; Environmental Pollutants; Female; Humans; Litter Size; Liver; Male; Mink; Organ Size; Polychlorinated Biphenyls; Random Allocation; Reproduction | 2012 |
Mechanism and kinetic study on the OH-initiated degradation of 2,3,7,8-tetrachlorinated dibenzofuran in atmosphere.
Topics: Air Pollutants; Atmosphere; Benzofurans; Computer Simulation; Dioxins; Furans; Hydroxyl Radical; Kinetics; Models, Chemical; Nitric Oxide; Oxidation-Reduction; Oxygen; Polychlorinated Dibenzodioxins; Water | 2012 |
Incidence of jaw lesions and activity and gene expression of hepatic P4501A enzymes in mink (Mustela vison) exposed to dietary 2,3,7,8-tetrachlorodibenzo-p-dioxin, 2,3,7,8-tetrachlorodibenzofuran, and 2,3,4,7,8-pentachlorodibenzofuran.
Topics: Animals; Benzofurans; Cytochrome P-450 CYP1A1; Diet; Endpoint Determination; Female; Gene Expression; Incidence; Jaw; Liver; Male; Mink; Polychlorinated Dibenzodioxins; Toxicity Tests, Chronic | 2012 |
[Analysis of characteristics of dioxin contamination in the chlor-alkali site that uses graphite anode for production].
Topics: Alkalies; Benzofurans; Chemical Industry; China; Dioxins; Electrodes; Environmental Pollutants; Graphite; Soil Pollutants | 2012 |
Cytochrome P4501A induction in primary cultures of embryonic European starling hepatocytes exposed to TCDD, PeCDF and TCDF.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Avian Proteins; Benzofurans; Cell Survival; Cells, Cultured; Chick Embryo; Chickens; Genes, Reporter; Hepatocytes; Lethal Dose 50; Luciferases; Polychlorinated Dibenzodioxins; Receptors, Aryl Hydrocarbon; Risk Assessment; RNA, Messenger; Starlings | 2013 |
PCDD/F formation in an iron/potassium-catalyzed diesel particle filter.
Topics: Benzofurans; Catalysis; Filtration; Iron; Polychlorinated Dibenzodioxins; Potassium | 2013 |
[Identification of two interference peaks during dioxin analysis for biological samples].
Topics: Benzofurans; DDT; Dioxins; Gas Chromatography-Mass Spectrometry; Hydrocarbons, Chlorinated; Mitotane; Pesticides; Polychlorinated Dibenzodioxins | 2014 |
Persistent Organic Pollutants Modify Gut Microbiota-Host Metabolic Homeostasis in Mice Through Aryl Hydrocarbon Receptor Activation.
Topics: Animals; Benzofurans; Bile Acids and Salts; Diet; Environmental Pollutants; Gastrointestinal Microbiome; Gastrointestinal Tract; Homeostasis; Liver; Male; Metabolomics; Mice, Inbred C57BL; Mice, Knockout; Microbiota; Receptors, Aryl Hydrocarbon; Receptors, Cytoplasmic and Nuclear; RNA, Ribosomal, 16S; Signal Transduction | 2015 |
Metabolomics Reveals that Aryl Hydrocarbon Receptor Activation by Environmental Chemicals Induces Systemic Metabolic Dysfunction in Mice.
Topics: Animals; Benzofurans; Dioxins; Environmental Pollutants; Fatty Acids; Gene Expression; Glucose; Lipid Metabolism; Liver; Magnetic Resonance Spectroscopy; Male; Metabolomics; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Receptors, Aryl Hydrocarbon | 2015 |
Relative sensitivities among avian species to individual and mixtures of aryl hydrocarbon receptor-active compounds.
Topics: Animals; Benzofurans; Chickens; Coturnix; Dioxins; Dioxins and Dioxin-like Compounds; Galliformes; Genes, Reporter; Luciferases; Polychlorinated Dibenzodioxins; Receptors, Aryl Hydrocarbon; Species Specificity; Transcriptional Activation | 2016 |
Abdominal Obesity and Insulin Resistance in People Exposed to Moderate-to-High Levels of Dioxin.
Topics: Adult; Benzofurans; Cross-Sectional Studies; Environmental Exposure; Environmental Pollutants; Female; Humans; Insulin Resistance; Male; Middle Aged; Obesity, Abdominal; Polychlorinated Dibenzodioxins; Sex Factors | 2016 |
Fast extraction of polychlorinated dibenzo-p-dioxin and polychlorinated dibenzofuran in sewage sludge and soil samples.
Topics: Acetonitriles; Agriculture; Benzofurans; Brazil; Chemical Fractionation; Cities; Dibenzofurans, Polychlorinated; Environmental Monitoring; Gas Chromatography-Mass Spectrometry; Limit of Detection; Polychlorinated Dibenzodioxins; Sewage; Soil Pollutants | 2017 |
Understanding the toxic potencies of xenobiotics inducing TCDD/TCDF-like effects.
Topics: Animals; Benzofurans; Hepatocytes; Models, Molecular; Polychlorinated Dibenzodioxins; Quantitative Structure-Activity Relationship; Rats; Receptors, Aryl Hydrocarbon; Xenobiotics | 2018 |
Co-administration of glutathione alleviates the toxic effects of 2,3,7,8 TCDF on the DNA integrity of sperm and in the testes of mice.
Topics: 17-Hydroxysteroid Dehydrogenases; Animals; Benzofurans; DNA; Glutathione; L-Lactate Dehydrogenase; Lipid Peroxidation; Male; Malondialdehyde; Mice; Oxidative Stress; Sperm Count; Spermatozoa; Superoxide Dismutase; Testis; Testosterone | 2018 |
Theoretical Investigations on the Reactivity of Methylidyne Radical toward 2,3,7,8-Tetrachlorodibenzo-
Topics: Benzofurans; Cyclization; Density Functional Theory; Kinetics; Molecular Dynamics Simulation; Polychlorinated Dibenzodioxins; Thermodynamics | 2018 |
Targeted metabolomics reveals that 2,3,7,8-tetrachlorodibenzofuran exposure induces hepatic steatosis in male mice.
Topics: Animals; Benzofurans; Fatty Liver; Humans; Liver; Male; Metabolomics; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease | 2020 |
Dioxin male rat reproductive toxicity mode of action and relative potency of 2,3,7,8-tetrachlorodibenzo-p-dioxin and 2,3,7,8-tetrachlorodibenzofuran characterized by fetal pituitary and testis transcriptome profiling.
Topics: Animals; Benzofurans; Female; Fetus; Gene Expression Profiling; Gene Expression Regulation, Developmental; Liver; Male; Pituitary Gland; Polychlorinated Dibenzodioxins; Pregnancy; Rats, Sprague-Dawley; Testis | 2020 |
Metabolic impact of persistent organic pollutants on gut microbiota.
Topics: Animals; Bacteria; Benzofurans; Carbon; Cecum; Citric Acid Cycle; Gastrointestinal Microbiome; Lipid Metabolism; Male; Mice; Mice, Inbred C57BL; Persistent Organic Pollutants; Polychlorinated Biphenyls; Polychlorinated Dibenzodioxins; Protein Transport; Pyruvic Acid | 2020 |
The aryl hydrocarbon receptor activates ceramide biosynthesis in mice contributing to hepatic lipogenesis.
Topics: Activation, Metabolic; Animals; Basic Helix-Loop-Helix Transcription Factors; Benzofurans; Ceramides; Gene Expression Regulation; Humans; Lipidomics; Lipogenesis; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptors, Aryl Hydrocarbon; Serine C-Palmitoyltransferase; Sphingomyelin Phosphodiesterase; Triglycerides | 2021 |
Liver-specific decrease in Tff3 gene expression in infant mice perinatally exposed to 2,3,7,8-tetrabromodibenzofuran or 2,3,7,8-tetrachlorodibenzo-p-dioxin.
Topics: Animals; Benzofurans; Female; Gene Expression; Liver; Male; Mice; Mice, Inbred C57BL; Trefoil Factor-3 | 2022 |