2,3,5,6-tetrachlorohydroquinone has been researched along with pentachlorophenol in 31 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (16.13) | 18.7374 |
| 1990's | 16 (51.61) | 18.2507 |
| 2000's | 4 (12.90) | 29.6817 |
| 2010's | 6 (19.35) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Behlen, LS; Copley, SD; Hlouchova, K; Pietari, JM; Rudolph, J | 1 |
| Apajalahti, JH; Salkinoja-Salonen, MS; Uotila, JS | 1 |
| Jansson, K; Jansson, V | 1 |
| Reigner, BG; Rigod, JF; Tozer, TN | 2 |
| Notten, WR; van den Berg, KJ; van Raaij, JA | 1 |
| Bragt, PC; Engel, R; Notten, WR; van den Berg, KJ; van Raaij, JA | 1 |
| Ehrlich, W | 1 |
| Bessems, JG; Geesink, G; Hendriks, W; Müller, F; van Bladeren, PJ; van Ommen, B | 1 |
| Apajalahti, JH; Salkinoja-Salonen, MS | 1 |
| Adang, AE; Brader, L; Müller, F; Posthumus, MA; van Bladeren, PJ; van Ommen, B | 1 |
| Ehrlich, W; Lochmann, ER; Mangir, M | 1 |
| Butte, W; Juhl, U; Witte, I | 1 |
| Inoue, S; Ito, K; Kawanishi, S; Naito, S; Ono, Y; Somiya, I; Yamamoto, K | 1 |
| Almstadt, E; Appel, KE; Dahlhaus, M; Henschke, P; Lüttgert, S | 2 |
| Ikeda, GJ; Sapienza, PP; Warr, PI | 1 |
| Almstadt, E; Appel, KE; Dahlhaus, M | 1 |
| Mabon, N; Moorthy, B; Randerath, K; Sriram, P | 1 |
| Claude, AA; Copley, SD; McCarthy, DL | 1 |
| Chu, SW; Ho, YS; Lien, HJ; Lin, JK; Liu, TH; Wang, YJ | 1 |
| Hasegawa, R; Inoue, T; Kang, KS; Sai, K; Trosko, JE; Upham, BL | 1 |
| Chevion, M; Lueken, A; Magnani, D; Stossberg, H; Witte, I; Zhu, BZ | 1 |
| Chevion, M; Kitrossky, N; Zhu, BZ | 1 |
| Ho, YS; Jeng, JH; Lee, CC; Su, HJ; Wang, YJ | 1 |
| Chang, WC; Ho, YS; Lee, CC; Liou, HB; Wang, YJ | 1 |
| Copley, SD; Hlouchova, K; Rudolph, J; Yadid, I | 1 |
| Chen, HM; Chen, RJ; Wang, BJ; Wang, YJ; Zhu, BZ | 1 |
| Burkhardt-Holm, P; Dorusch, F; Hollender, J; Pietsch, C | 1 |
| Behlen, LS; Copley, SD; Erbse, AH; Rudolph, J | 1 |
| Chen, HM; Lee, YH; Wang, YJ | 1 |
2 review(s) available for 2,3,5,6-tetrachlorohydroquinone and pentachlorophenol
| Article | Year |
|---|---|
Oxidative DNA lesions in V79 cells mediated by pentachlorophenol metabolites.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Carcinogens, Environmental; Cell Line; Chloranil; Cricetinae; Deoxyguanosine; DNA; DNA Damage; DNA, Single-Stranded; Hydroquinones; Mice; Pentachlorophenol; Reactive Oxygen Species | 1996 |
ROS-triggered signaling pathways involved in the cytotoxicity and tumor promotion effects of pentachlorophenol and tetrachlorohydroquinone.
Topics: Animals; Carcinogens; Environmental Exposure; Environmental Pollutants; Humans; Hydroquinones; Oxidative Stress; Pentachlorophenol; Reactive Oxygen Species; Signal Transduction | 2015 |
29 other study(ies) available for 2,3,5,6-tetrachlorohydroquinone and pentachlorophenol
| Article | Year |
|---|---|
Pentachlorophenol hydroxylase, a poorly functioning enzyme required for degradation of pentachlorophenol by Sphingobium chlorophenolicum.
Topics: Biodegradation, Environmental; Catalysis; Hydrogen Peroxide; Metabolic Networks and Pathways; Mixed Function Oxygenases; Pentachlorophenol; Pesticides; Sphingomonadaceae; Structure-Activity Relationship; Substrate Specificity | 2012 |
Dechlorination of pentachlorophenol by membrane bound enzymes of Rhodococcus chlorophenolicus PCP-I.
Topics: Biodegradation, Environmental; Cytochrome P-450 Enzyme System; Hydroquinones; Hydroxylation; Membranes; Pentachlorophenol; Rhodococcus | 1991 |
Induction of micronuclei in V79 Chinese hamster cells by tetrachlorohydroquinone, a metabolite of pentachlorophenol.
Topics: Animals; Cells, Cultured; Cricetinae; Cricetulus; Dimethyl Sulfoxide; DNA Damage; Hydroquinones; Micronuclei, Chromosome-Defective; Micronucleus Tests; Pentachlorophenol | 1992 |
Disposition, bioavailability, and serum protein binding of pentachlorophenol in the B6C3F1 mouse.
Topics: Administration, Oral; Animals; Blood Proteins; Data Interpretation, Statistical; Half-Life; Hydroquinones; Injections, Intravenous; Male; Mice; Pentachlorophenol; Protein Binding | 1992 |
Hexachlorobenzene and its metabolites pentachlorophenol and tetrachlorohydroquinone: interaction with thyroxine binding sites of rat thyroid hormone carriers ex vivo and in vitro.
Topics: Animals; Binding Sites; Binding, Competitive; Hexachlorobenzene; Hydroquinones; Hypothyroidism; Injections, Intraperitoneal; Pentachlorophenol; Rats; Thyroxine | 1991 |
Effects of hexachlorobenzene and its metabolites pentachlorophenol and tetrachlorohydroquinone on serum thyroid hormone levels in rats.
Topics: Animals; Dose-Response Relationship, Drug; Hexachlorobenzene; Hydroquinones; Male; Pentachlorophenol; Rats; Thyroid Gland; Thyroxine; Triiodothyronine | 1991 |
Simultaneous assay of pentachlorophenol and its metabolite, tetrachlorohydroquinone, by gas chromatography without derivatization.
Topics: Animals; Chromatography, Gas; Feces; Glucuronidase; Hydrolysis; Hydroquinones; Pentachlorophenol; Rats; Sulfatases | 1990 |
The effect of pentachlorophenol and its metabolite tetrachlorohydroquinone on cell growth and the induction of DNA damage in Chinese hamster ovary cells.
Topics: Animals; Cell Division; Cell Line; Chlorophenols; DNA Damage; Hydroquinones; Kinetics; Pentachlorophenol | 1990 |
The relation between the oxidative biotransformation of hexachlorobenzene and its porphyrinogenic activity.
Topics: Animals; Biotransformation; Chemical and Drug Induced Liver Injury; Chlorobenzenes; Cytochrome P-450 Enzyme Inhibitors; Female; Hexachlorobenzene; Hydroquinones; In Vitro Techniques; Liver Diseases; Male; Microsomes, Liver; Oxidation-Reduction; Pentachlorophenol; Porphyrias; Rats; Rats, Inbred Strains; Troleandomycin | 1989 |
Complete dechlorination of tetrachlorohydroquinone by cell extracts of pentachlorophenol-induced Rhodococcus chlorophenolicus.
Topics: Aerobiosis; Anaerobiosis; Biotransformation; Chlorophenols; Hydroquinones; Kinetics; Mass Spectrometry; Pentachlorophenol; Rhodococcus | 1987 |
The microsomal metabolism of hexachlorobenzene. Origin of the covalent binding to protein.
Topics: Animals; Ascorbic Acid; Chloranil; Chlorobenzenes; Glutathione; Hexachlorobenzene; Hydroquinones; In Vitro Techniques; Male; Microsomes; Pentachlorophenol; Protein Binding; Rats; Rats, Inbred Strains | 1986 |
The effect of pentachlorophenol and its metabolite tetrachlorohydroquinone on RNA, protein, and ribosome synthesis in Saccharomyces cells.
Topics: Chlorophenols; Fungal Proteins; Hydroquinones; Kinetics; Pentachlorophenol; Ribosomes; RNA, Fungal; Saccharomyces | 1987 |
Metabolism of pentachlorophenol to tetrachlorohydroquinone by human liver homogenate.
Topics: Animals; Chlorophenols; Female; Humans; Hydroquinones; In Vitro Techniques; Liver; Male; Middle Aged; Pentachlorophenol; Rats; Rats, Inbred Strains; Species Specificity | 1985 |
Role of active oxygen species in DNA damage by pentachlorophenol metabolites.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Base Sequence; Cattle; Copper; Deoxyguanosine; DNA; DNA Damage; Free Radical Scavengers; Hydroquinones; Molecular Sequence Data; Mutagens; NAD; Oxidation-Reduction; Pentachlorophenol; Phenanthrolines; Phosphorus Radioisotopes; Proto-Oncogene Proteins p21(ras); Reactive Oxygen Species; Thymus Gland | 1994 |
Induction of 8-hydroxy-2-deoxyguanosine and single-strand breaks in DNA of V79 cells by tetrachloro-p-hydroquinone.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Carcinogens, Environmental; Cells, Cultured; Cricetinae; Cricetulus; Deoxyguanosine; DNA Damage; DNA, Single-Stranded; Dose-Response Relationship, Drug; Fibroblasts; Hydroquinones; Hydroxyl Radical; Least-Squares Analysis; Lung; Oxidation-Reduction; Oxidative Stress; Pentachlorophenol; Reactive Oxygen Species | 1995 |
Disposition and metabolism of radiolabelled pentachloroanisole in rats and rabbits.
Topics: Administration, Oral; Animals; Anisoles; Carbon Radioisotopes; Chromatography, Thin Layer; Feces; Half-Life; Hydroquinones; Isotope Labeling; Male; Pentachlorophenol; Rabbits; Radioisotope Dilution Technique; Rats; Rats, Sprague-Dawley; Scintillation Counting; Tissue Distribution | 1994 |
The pentachlorophenol metabolite tetrachloro-p-hydroquinone induces the formation of 8-hydroxy-2-deoxyguanosine in liver DNA of male B6C3F1 mice.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Deoxyguanosine; Diet; DNA; DNA Damage; Hydroquinones; Hydroxyl Radical; Injections, Intraperitoneal; Liver; Male; Mice; Oxidation-Reduction; Pentachlorophenol; Reactive Oxygen Species | 1994 |
Tamoxifen: evidence by 32P-postlabeling and use of metabolic inhibitors for two distinct pathways leading to mouse hepatic DNA adduct formation and identification of 4-hydroxytamoxifen as a proximate metabolite.
Topics: Animals; DNA; DNA Adducts; Female; Hydroquinones; Isotope Labeling; Kidney; Liver; Lung; Mice; Mice, Inbred ICR; Pentachlorophenol; Phosphorus Radioisotopes; Rats; Rats, Sprague-Dawley; Tamoxifen | 1994 |
In vivo levels of chlorinated hydroquinones in a pentachlorophenol-degrading bacterium.
Topics: Cell Extracts; Cytoplasm; Edetic Acid; Escherichia coli; Gas Chromatography-Mass Spectrometry; Gram-Negative Aerobic Bacteria; Hydrolases; Hydroquinones; Mixed Function Oxygenases; Pentachlorophenol | 1997 |
Induction of glutathione depletion, p53 protein accumulation and cellular transformation by tetrachlorohydroquinone, a toxic metabolite of pentachlorophenol.
Topics: 3T3 Cells; Acetylcysteine; Animals; Apoptosis; Carcinogens; Cell Transformation, Neoplastic; Chromosomes; DNA Fragmentation; Electrophoresis, Capillary; Glutathione; Hydroquinones; Mice; Mice, Inbred C3H; Pentachlorophenol; Pesticides; Tumor Suppressor Protein p53 | 1997 |
Inhibitory effect of pentachlorophenol on gap junctional intercellular communication in rat liver epithelial cells in vitro.
Topics: Animals; Cell Line; Connexin 43; Dose-Response Relationship, Drug; Epithelial Cells; Gap Junctions; Hydroquinones; Liver; Pentachlorophenol; Rats; Time Factors | 1998 |
Protection by desferrioxamine and other hydroxamic acids against tetrachlorohydroquinone-induced cyto- and genotoxicity in human fibroblasts.
Topics: Cell Line; Cell Survival; Deferoxamine; DNA Damage; Fibroblasts; Free Radical Scavengers; Free Radicals; Humans; Hydroquinones; Hydroxamic Acids; Mutagens; Oxidation-Reduction; Pentachlorophenol | 2000 |
Evidence for production of hydroxyl radicals by pentachlorophenol metabolites and hydrogen peroxide: A metal-independent organic Fenton reaction.
Topics: Chelating Agents; Hydrogen Peroxide; Hydroquinones; Hydroxybenzoates; Hydroxyl Radical; Iron; Kinetics; Pentachlorophenol; Resorcinols | 2000 |
Different cell death mechanisms and gene expression in human cells induced by pentachlorophenol and its major metabolite, tetrachlorohydroquinone.
Topics: Apoptosis; bcl-2-Associated X Protein; Carcinogens; Cell Death; Cell Line; Cellular Apoptosis Susceptibility Protein; DNA Fragmentation; Environmental Pollutants; Flow Cytometry; Gene Expression; HeLa Cells; HSP70 Heat-Shock Proteins; Humans; Hydroquinones; In Situ Nick-End Labeling; Liver; Pentachlorophenol; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Tumor Cells, Cultured; Urinary Bladder | 2000 |
Oxidative stress and liver toxicity in rats and human hepatoma cell line induced by pentachlorophenol and its major metabolite tetrachlorohydroquinone.
Topics: Alanine Transaminase; Animals; Apoptosis; Aspartate Aminotransferases; Cellular Apoptosis Susceptibility Protein; Dinoprost; F2-Isoprostanes; Humans; Hydroquinones; Liver; Male; Oxidative Stress; Pentachlorophenol; Proteins; Rats; Rats, Sprague-Dawley; Tumor Cells, Cultured; Vitamin E | 2001 |
Sequestration of a highly reactive intermediate in an evolving pathway for degradation of pentachlorophenol.
Topics: Amino Acid Sequence; Bacterial Proteins; Biocatalysis; Biodegradation, Environmental; Chloranil; Flavin Mononucleotide; Hydroquinones; Kinetics; Metabolic Networks and Pathways; Mixed Function Oxygenases; Molecular Sequence Data; Molecular Structure; Mutation; NAD; Oxidation-Reduction; Pentachlorophenol; Protein Binding; Quinone Reductases; Sequence Homology, Amino Acid; Sphingomonadaceae; Substrate Specificity | 2013 |
The pentachlorophenol metabolite tetrachlorohydroquinone induces massive ROS and prolonged p-ERK expression in splenocytes, leading to inhibition of apoptosis and necrotic cell death.
Topics: Animals; Apoptosis; Cell Death; Extracellular Signal-Regulated MAP Kinases; Flow Cytometry; Hydroquinones; Male; Mice; Mice, Inbred ICR; Necrosis; Pentachlorophenol; Reactive Oxygen Species; Spleen | 2014 |
Cytotoxic effects of pentachlorophenol (PCP) and its metabolite tetrachlorohydroquinone (TCHQ) on liver cells are modulated by antioxidants.
Topics: Animals; Antioxidants; Ascorbic Acid; Cell Line; Cell Survival; Fish Proteins; Hepatocytes; Hydroquinones; Inhibitory Concentration 50; Oncorhynchus mykiss; Oxidative Stress; Pentachlorophenol; Quercetin; Reactive Oxygen Species; Superoxide Dismutase; Water Pollutants, Chemical | 2014 |
A radical intermediate in the conversion of pentachlorophenol to tetrachlorohydroquinone by Sphingobium chlorophenolicum.
Topics: Bacterial Proteins; Benzoquinones; Biocatalysis; Biotransformation; Catalytic Domain; Electron Spin Resonance Spectroscopy; Environmental Pollutants; Hydrocarbons, Chlorinated; Hydroquinones; Kinetics; Mixed Function Oxygenases; NADP; Oxidation-Reduction; Pentachlorophenol; Protein Stability; Quinone Reductases; Sphingomonadaceae | 2014 |