Page last updated: 2024-08-17

2,3,4,6-tetrachlorophenol and complestatin

2,3,4,6-tetrachlorophenol has been researched along with complestatin in 35 studies

Research

Studies (35)

Timeframe	Studies, this research(%)	All Research%
pre-1990	3 (8.57)	18.7374
1990's	7 (20.00)	18.2507
2000's	14 (40.00)	29.6817
2010's	9 (25.71)	24.3611
2020's	2 (5.71)	2.80

Authors

Authors	Studies
Kaneko, I; Kimura, S; Mitamura, K; Momota, K; Shimada, K	1
Kamoshida, K; Kaneko, I; Takahashi, S	1
Fujioka, T; Furihata, K; Kaneko, I; Seto, H; Takahashi, S	1
Austen, KF; Fearon, DT; Kaneko, I	1
Ikeda, H; Matsumoto, A; Matsuzaki, K; Ogino, T; Omura, S; Tanaka, H; Woodruff, HB	1
Endo, A; Hasumi, K; Tachikawa, K	2
Ikeda, H; Matsumoto, A; Matsuzaki, K; Nakashima, H; Ogino, T; Omura, S; Tanaka, H; Woodruff, HB	1
Matsuzaki, K; Ogino, T; Omura, S; Sunazuka, T; Tanaka, H	1
Elder, AM; Rich, DH	1
Chiu, HT; Eide, J; Fredenburg, RA; Hubbard, BK; Khosla, C; Shah, AN; Walsh, CT	1
Felock, P; Genilloud, O; Hazuda, D; Heimbuch, B; Jayasuriya, H; Lingham, RB; Salituro, GM; Shafiee, A; Silverman, KC; Singh, SB; Teran, A; Vilella, D; Zink, DL	1
Chang, SY; Choi, JS; Chung, JM; Gwag, BJ; Joo, CK; Oh, S; Ryoo, IJ; Seo, SY; Yoo, ID; Yun, BS	1
Lee, SY; Oh, S; Ryoo, IJ; Shin, MH; Yoo, ID; Yun, B	1
Chan, TM; Dai, P; Gullo, VP; Hegde, VR; Jenh, CH; Patel, M; Pramanik, BN; Puar, MS; Silver, J	1
Kim, EC; Kim, YM; Kwon, YG; Lee, KS; Min, JK; Ryoo, IJ; Won, MH; Yoo, I-; Yun, BS	1
Chikanishi, T; Harada, T; Hasumi, K; Miura, Y; Ohyama, S	1
Barbosa, J; Chruma, JJ; Han, Q; Smith, AB	1
Deng, H; Hoveyda, AH; Shinohara, T; Snapper, ML	1
Akiba, A; Arima, S; Harigaya, Y; Itou, F; Kai, T; Okada, C; Satou, T; Takeda, K; Yamada, Y; Yoshida, K	1
Bois-Choussy, M; Jia, Y; Zhu, J	2
Alami, M; Bignon, J; Brion, JD; De Losada, JR; Dubois, J; Hamze, A; Liu, JM; Messaoudi, S; Peyrat, JF; Provot, O; Thoret, S; Tréguier, B; Wdzieczak-Bakala, J	1
Boger, DL; Garfunkle, J; Kimball, FS; Shimamura, H; Takizawa, S; Tomishima, M; Trzupek, JD	1
Bois-Choussy, M; Jia, Y; Wang, Z; Zhu, J	1
Boger, DL; Breazzano, SP; Garfunkle, J; Kimball, FS; Shimamura, H; Trzupek, JD	1
Alami, M; Bignon, J; Brion, JD; Hamze, A; Provot, O; Rasolofonjatovo, E; Thoret, S	1
Wang, Q; Zhu, J	1
Alami, M; Bignon, J; Brion, JD; Desravines, D; Dubois, J; Hamze, A; Provot, O; Rasolofonjatovo, E; Rodrigo, J; Wdzieczak-Bakala, J	1
Kamal, A; Kapure, JS; Kumar, GB; Mahesh, R; Reddy, VS; Sayeeda, IB; Shaik, AB; Vishnuvardhan, MV	1
Kim, HJ; Kim, WG; Kwon, YJ	1
Choi, HY; Kim, GW; Kim, WG; Park, OK	1
Cryle, MJ; Ulrich, V	1
Brun, YV; Coombes, BK; Culp, EJ; Fiebig-Comyn, AA; Hsu, YP; Koteva, K; Sychantha, D; Van Nieuwenhze, MS; Waglechner, N; Wang, W; Wright, GD	1
Choi, HY; Kim, WG; Park, JS	1

Reviews

1 review(s) available for 2,3,4,6-tetrachlorophenol and complestatin

Article	Year
Access to macrocycles with an endo aryl ether and an endo aryl-aryl bond, development and application. Chimia, 2011, Volume: 65, Issue:3 Topics: Catalysis; Chlorophenols; Complement Pathway, Alternative; Ethers; Heterocyclic Compounds; Peptides, Cyclic	2011

Other Studies

34 other study(ies) available for 2,3,4,6-tetrachlorophenol and complestatin

Article	Year
Inhibition of human immunodeficiency virus type-1-induced syncytium formation and cytopathicity by complestatin. Biochemical and biophysical research communications, 1991, Aug-30, Volume: 179, Issue:1 Topics: Amino Acids; Antiviral Agents; Cell Fusion; Cell Line; Chlorophenols; Giant Cells; HIV-1; Humans; Peptides, Cyclic; RNA-Directed DNA Polymerase; T-Lymphocytes	1991
Complestatin, a potent anti-complement substance produced by Streptomyces lavendulae. I. Fermentation, isolation and biological characterization. The Journal of antibiotics, 1989, Volume: 42, Issue:2 Topics: Amino Acids; Anaphylaxis; Animals; Anti-Bacterial Agents; Chlorophenols; Chymotrypsin; Complement Activation; Complement Inactivator Proteins; Erythrocytes; Fermentation; Guinea Pigs; Hemolysis; Peptides, Cyclic; Streptomyces; Trypsin	1989
[Structure of complestatin, a potent inhibitor of human complement]. The Japanese journal of antibiotics, 1988, Volume: 41, Issue:5 Topics: Amino Acids; Chemical Phenomena; Chemistry; Chlorophenols; Complement Inactivator Proteins; Humans; Peptides, Cyclic	1988
Inhibition of the alternative pathway of human complement in vitro by a natural microbial product, complestatin. Journal of immunology (Baltimore, Md. : 1950), 1980, Volume: 124, Issue:3 Topics: Amino Acids; Animals; Chlorophenols; Complement Activation; Complement C3-C5 Convertases; Complement C3b; Complement Pathway, Alternative; Dose-Response Relationship, Drug; Erythrocytes; Hemolysis; Humans; Peptides, Cyclic; Rabbits; Receptors, Complement; Sheep; Streptomyces	1980
Chloropeptins I and II, novel inhibitors against gp120-CD4 binding from Streptomyces sp. The Journal of antibiotics, 1994, Volume: 47, Issue:10 Topics: Antiviral Agents; CD4 Antigens; Chlorophenols; HIV; HIV Envelope Protein gp120; Humans; Oligopeptides; Peptides, Cyclic; Streptomycin	1994
Enhancement of plasminogen binding to U937 cells and fibrin by complestatin. Thrombosis and haemostasis, 1997, Volume: 77, Issue:1 Topics: Cell Line; Chlorophenols; Complement Inactivator Proteins; Fibrin; Humans; Monocytes; Oligopeptides; Peptides, Cyclic; Plasminogen; Protein Binding	1997
Chloropeptins, new anti-HIV antibiotics inhibiting gp120-CD4 binding from Streptomyces sp. I. Taxonomy, fermentation, isolation, and physico-chemical properties and biological activities. The Journal of antibiotics, 1997, Volume: 50, Issue:1 Topics: Anti-Bacterial Agents; Anti-HIV Agents; CD4-Positive T-Lymphocytes; Chlorophenols; Fermentation; HeLa Cells; HIV Envelope Protein gp120; Humans; Oligopeptides; Peptides, Cyclic; Streptomyces; Zidovudine	1997
Chloropeptins, new anti-HIV antibiotics inhibiting gp120-CD4 binding from Streptomyces sp. II. Structure elucidation of chloropeptin I. The Journal of antibiotics, 1997, Volume: 50, Issue:1 Topics: Anti-Bacterial Agents; Anti-HIV Agents; CD4-Positive T-Lymphocytes; Chlorophenols; HIV Envelope Protein gp120; Oligopeptides; Peptides, Cyclic	1997
Enhancement of plasminogen binding and fibrinolysis by chloropeptin I. Thrombosis research, 1997, Sep-15, Volume: 87, Issue:6 Topics: Anti-Bacterial Agents; Binding Sites; Chlorophenols; Fibrin; Fibrinolysin; Fibrinolysis; Humans; Kinetics; Lysine; Oligopeptides; Peptides, Cyclic; Plasma; Plasminogen; Protein Binding; Tissue Plasminogen Activator; Tumor Cells, Cultured	1997
Two syntheses of the 16- and 17-membered DEF ring systems of chloropeptin and complestatin. Organic letters, 1999, Nov-04, Volume: 1, Issue:9 Topics: Chlorophenols; Molecular Structure; Oligopeptides; Peptides, Cyclic	1999
Molecular cloning and sequence analysis of the complestatin biosynthetic gene cluster. Proceedings of the National Academy of Sciences of the United States of America, 2001, Jul-17, Volume: 98, Issue:15 Topics: Base Sequence; Chlorophenols; Cloning, Molecular; DNA, Bacterial; Genes, Bacterial; Molecular Sequence Data; Molecular Structure; Multigene Family; Oligopeptides; Peptides, Cyclic; Sequence Analysis, DNA; Streptomyces; Vancomycin	2001
The complestatins as HIV-1 integrase inhibitors. Efficient isolation, structure elucidation, and inhibitory activities of isocomplestatin, chloropeptin I, new complestatins, A and B, and acid-hydrolysis products of chloropeptin I. Journal of natural products, 2001, Volume: 64, Issue:7 Topics: Anti-HIV Agents; Chlorophenols; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; HIV Envelope Protein gp120; HIV Integrase; HIV Integrase Inhibitors; HIV-1; Leukocyte Common Antigens; Magnetic Resonance Spectroscopy; Models, Chemical; Molecular Structure; Oligopeptides; Peptides, Cyclic; Stereoisomerism; Streptomyces; Structure-Activity Relationship	2001
Complestatin is a noncompetitive peptide antagonist of N-methyl-D-aspartate and alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid/kainate receptors: secure blockade of ischemic neuronal death. The Journal of pharmacology and experimental therapeutics, 2001, Volume: 299, Issue:1 Topics: Animals; Apoptosis; Brain Ischemia; Calcium; Cell Death; Chlorophenols; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glucose; Kainic Acid; Mice; Neurons; Neuroprotective Agents; Oligopeptides; Oxidative Stress; Oxygen; Patch-Clamp Techniques; Peptides, Cyclic; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Retinal Vessels	2001
Complestatin antagonizes the AMPA/kainate-induced neurotoxicity in cultured chick telencephalic neurons. Neurochemical research, 2002, Volume: 27, Issue:4 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Chick Embryo; Chickens; Chlorophenols; Excitatory Amino Acid Antagonists; Kainic Acid; Neurons; Oligopeptides; Peptides, Cyclic; Phorbol 12,13-Dibutyrate; Quinoxalines; Receptors, AMPA; Receptors, Kainic Acid; Staurosporine; Telencephalon; Time Factors	2002
Condensed aromatic peptide family of microbial metabolites, inhibitors of CD28-CD80 interactions. Bioorganic & medicinal chemistry letters, 2003, Feb-10, Volume: 13, Issue:3 Topics: B7-1 Antigen; Binding, Competitive; CD28 Antigens; Chlorophenols; Fermentation; Magnetic Resonance Spectroscopy; Peptides; Peptides, Cyclic; Spectrometry, Mass, Fast Atom Bombardment; Spectrophotometry, Ultraviolet; Streptomyces	2003
Complestatin prevents apoptotic cell death: inhibition of a mitochondrial caspase pathway through AKT/PKB activation. Biochemical and biophysical research communications, 2004, Jan-02, Volume: 313, Issue:1 Topics: Apoptosis; Apoptosis Regulatory Proteins; BH3 Interacting Domain Death Agonist Protein; Carrier Proteins; Caspase Inhibitors; Caspases; Cell Survival; Chlorophenols; Cytochromes c; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; HeLa Cells; Humans; Immunoblotting; Membrane Glycoproteins; Mitochondria; Peptides, Cyclic; Phosphorylation; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; TNF-Related Apoptosis-Inducing Ligand; Tumor Necrosis Factor-alpha	2004
Nonlysine-analog plasminogen modulators promote autoproteolytic generation of plasmin(ogen) fragments with angiostatin-like activity. European journal of biochemistry, 2004, Volume: 271, Issue:4 Topics: Amino Acids; Aminocaproic Acid; Angiostatins; Animals; Benzopyrans; Binding Sites; Cattle; Cell Division; Cell Line, Tumor; Chlorophenols; CHO Cells; Cricetinae; Endothelium, Vascular; Fibrinolysin; Humans; Mass Spectrometry; Mice; Peptide Fragments; Peptides, Cyclic; Plasminogen; Plasminogen Activators; Pyrrolidinones; Sequence Analysis, Protein; Umbilical Veins	2004
Complestatin synthetic studies; the effect of the amino acid configuration on peptide backbone conformation in the common western BCD macrocycle. Bioorganic & medicinal chemistry letters, 2004, Apr-05, Volume: 14, Issue:7 Topics: Amino Acids; Chlorophenols; Heterocyclic Compounds; Models, Molecular; Peptides; Peptides, Cyclic; Protein Conformation	2004
Isocomplestatin: total synthesis and stereochemical revision. Journal of the American Chemical Society, 2005, May-25, Volume: 127, Issue:20 Topics: Chlorophenols; Molecular Conformation; Oligopeptides; Peptides, Cyclic; Stereoisomerism; Streptomyces	2005
Synthesis of linear tripeptides for right-hand segments of complestatin. Chemical & pharmaceutical bulletin, 2005, Volume: 53, Issue:10 Topics: Chlorophenols; Crystallography, X-Ray; Models, Molecular; Molecular Conformation; Oligopeptides; Peptides, Cyclic; Stereoisomerism	2005
Synthesis of DEFG ring of complestatin and chloropeptin I: highly atropdiastereoselective macrocyclization by intramolecular Suzuki-Miyaura reaction. Organic letters, 2007, Jun-07, Volume: 9, Issue:12 Topics: Catalysis; Chlorophenols; Cyclization; Molecular Conformation; Palladium; Peptides; Peptides, Cyclic; Stereoisomerism	2007
Synthesis of diastereomers of complestatin and chloropeptin I: substrate-dependent atropstereoselectivity of the intramolecular Suzuki-Miyaura reaction. Angewandte Chemie (International ed. in English), 2008, Volume: 47, Issue:22 Topics: Anti-HIV Agents; Chlorophenols; HIV-1; Humans; Peptides, Cyclic; Stereoisomerism; Streptomyces	2008
Isocombretastatins a versus combretastatins a: the forgotten isoCA-4 isomer as a highly promising cytotoxic and antitubulin agent. Journal of medicinal chemistry, 2009, Jul-23, Volume: 52, Issue:14 Topics: Antineoplastic Agents; Bibenzyls; Cell Line, Tumor; Cell Proliferation; Chlorophenols; Humans; Models, Molecular; Molecular Conformation; Peptides, Cyclic; Stereoisomerism; Tubulin Modulators	2009
Total synthesis of chloropeptin II (complestatin) and chloropeptin I. Journal of the American Chemical Society, 2009, Nov-11, Volume: 131, Issue:44 Topics: Chlorophenols; Cyclization; Indoles; Macrocyclic Compounds; Peptides, Cyclic	2009
Total synthesis of complestatin (chloropeptin II). Angewandte Chemie (International ed. in English), 2010, Mar-08, Volume: 49, Issue:11 Topics: Anti-Bacterial Agents; Chlorophenols; Peptides, Cyclic; Stereoisomerism; Streptomyces	2010
Total synthesis of complestatin: development of a Pd(0)-mediated indole annulation for macrocyclization. Journal of the American Chemical Society, 2010, Jun-09, Volume: 132, Issue:22 Topics: Chlorophenols; Cyclization; Indoles; Macrocyclic Compounds; Palladium; Peptides, Cyclic	2010
Regioselective hydrostannation of diarylalkynes directed by a labile ortho bromine atom: an easy access to stereodefined triarylolefins, hybrids of combretastatin A-4 and isocombretastatin A-4. European journal of medicinal chemistry, 2010, Volume: 45, Issue:9 Topics: Alkenes; Alkynes; Animals; Antineoplastic Agents; Bromine; Cell Line, Tumor; Cell Proliferation; Chlorophenols; Humans; Organotin Compounds; Peptides, Cyclic; Stereoisomerism; Stilbenes; Substrate Specificity	2010
Conformationnally restricted naphthalene derivatives type isocombretastatin A-4 and isoerianin analogues: synthesis, cytotoxicity and antitubulin activity. European journal of medicinal chemistry, 2012, Volume: 52 Topics: Antineoplastic Agents; Benzene; Bibenzyls; Cell Line, Tumor; Chlorophenols; Humans; Models, Molecular; Molecular Conformation; Naphthalenes; Peptides, Cyclic; Phenol; Protein Multimerization; Protein Structure, Quaternary; Tubulin; Tubulin Modulators	2012
Synthesis of phenstatin/isocombretastatin-chalcone conjugates as potent tubulin polymerization inhibitors and mitochondrial apoptotic inducers. Organic & biomolecular chemistry, 2015, Apr-07, Volume: 13, Issue:13 Topics: Apoptosis; Binding, Competitive; Caspase 9; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Chalcone; Chemistry Techniques, Synthetic; Chlorophenols; DNA Fragmentation; Drug Screening Assays, Antitumor; Enzyme Activation; Humans; Membrane Potential, Mitochondrial; Mitochondria; Models, Molecular; Peptides, Cyclic; Protein Multimerization; Protein Structure, Secondary; Tubulin; Tubulin Modulators	2015
Complestatin exerts antibacterial activity by the inhibition of fatty acid synthesis. Biological & pharmaceutical bulletin, 2015, Volume: 38, Issue:5 Topics: Anti-Bacterial Agents; Chlorophenols; Drug Resistance; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH); Enzyme Inhibitors; Fatty Acids; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Oligopeptides; Peptides, Cyclic; Staphylococcal Infections; Staphylococcus aureus; Streptomyces	2015
Generation of New Complestatin Analogues by Heterologous Expression of the Complestatin Biosynthetic Gene Cluster from Streptomyces chartreusis AN1542. Chembiochem : a European journal of chemical biology, 2016, 09-15, Volume: 17, Issue:18 Topics: Anti-Bacterial Agents; Chlorophenols; Microbial Sensitivity Tests; Molecular Conformation; Multigene Family; Peptides, Cyclic; Streptomyces; Structure-Activity Relationship	2016
SNaPe: a versatile method to generate multiplexed protein fusions using synthetic linker peptides for in vitro applications. Journal of peptide science : an official publication of the European Peptide Society, 2017, Volume: 23, Issue:1 Topics: Amino Acid Sequence; Aminoacyltransferases; Anti-Bacterial Agents; Chemistry Techniques, Synthetic; Chlorophenols; Cross-Linking Reagents; Escherichia coli; Gene Expression; Gene Library; Glycopeptides; Peptide Synthases; Peptides; Peptides, Cyclic; Recombinant Fusion Proteins	2017
Evolution-guided discovery of antibiotics that inhibit peptidoglycan remodelling. Nature, 2020, Volume: 578, Issue:7796 Topics: Actinobacteria; Animals; Anti-Bacterial Agents; Biosynthetic Pathways; Cell Wall; Chlorophenols; Disease Models, Animal; Drug Discovery; Drug Resistance, Microbial; Female; Methicillin-Resistant Staphylococcus aureus; Mice; Microbial Sensitivity Tests; Multigene Family; N-Acetylmuramoyl-L-alanine Amidase; Peptides, Cyclic; Peptidoglycan; Phylogeny; Skin; Staphylococcal Infections	2020
The Nitrite Transporter Facilitates Biofilm Formation via Suppression of Nitrite Reductase and Is a New Antibiofilm Target in Pseudomonas aeruginosa. mBio, 2020, 07-07, Volume: 11, Issue:4 Topics: Anti-Bacterial Agents; Bacterial Proteins; Biofilms; Chlorophenols; Escherichia coli; Gene Expression Regulation, Bacterial; Gene Library; Nitric Oxide; Nitrite Reductases; Nitrites; Peptides, Cyclic; Pseudomonas aeruginosa; Virulence	2020