2,3,4,6-tetrachlorophenol has been researched along with carbamates in 55 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (3.64) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (1.82) | 29.6817 |
| 2010's | 3 (5.45) | 24.3611 |
| 2020's | 49 (89.09) | 2.80 |
| Authors | Studies |
|---|---|
| Romaniuk, K; Tarczyński, S | 1 |
| Coye, MJ; Lowe, JA; Maddy, KJ | 1 |
| Dreiher, J; Kordysh, E | 1 |
| Ayotte, P; Côté, S; Drescher, O; Forde, MS; Gaudreau, E; Laouan Sidi, EA; Robertson, L | 1 |
| Krátký, M; Štěpánková, Š; Vinšová, J; Vorčáková, K | 1 |
| DiVentura, BD; French, JA; Kasteleijn-Nolst Trenite, DGA; Krauss, GL; Mizne, S; Pollard, JR | 1 |
| Keam, SJ | 1 |
| Aschenbrenner, DS | 1 |
| Greene, SA; Kamin, M; Vernillet, L | 1 |
| Glenn, K; Greene, SA; Kim, HW; Melnick, SM; Vernillet, L | 1 |
| Dhir, A | 1 |
| Glenn, KJ; Jang, IS; Jeon, BH; Melnick, SM; Nakamura, M; Neupane, C; Park, JB; Sharma, R; Shin, H | 1 |
| Ferrari, L; Nisman, A; Pegan, A; Ursino, J | 1 |
| Aboumatar, S; Borchert, L; Gelfand, M; Halford, JJ; Kamin, M; Klein, P; Krauss, GL; Rosenfeld, WE; Sperling, MR; Vossler, DG; Wechsler, R | 1 |
| Chung, SS; French, JA; Kamin, M; Kowalski, J; Krauss, GL; Lee, SK; Maciejowski, M; Mizne, S; Rosenfeld, WE; Sperling, MR | 1 |
| Buckley, CT; DeMaagd, G; Waters, OR | 1 |
| Bauer, S; Mann, C; Rosenow, F; Strzelczyk, A; Willems, LM | 1 |
| Brigo, F; Del Giovane, C; Lattanzi, S; Silvestrini, M; Striano, P; Trinka, E; Zaccara, G | 1 |
| Mula, M | 1 |
| Steinhoff, BJ | 2 |
| Wheless, JW | 1 |
| Campbell, A; Guignet, M; White, HS | 1 |
| Główka, FK; Karaźniewcz-Łada, M; Sommerfeld-Klatta, K; Zielińska-Psuja, B | 1 |
| Malinowski, B; Puk, O; Wiciński, M | 1 |
| Coe, P; Elizebath, R; Gutierrez, EG; Krauss, GL; Yang, J; Zhang, E | 1 |
| Löscher, W; Sills, GJ; White, HS | 1 |
| Cutillo, G; Hirsch, LJ; Tolba, H | 1 |
| Ferrari, L; Nisman, A; Rosenfeld, WE | 1 |
| Wang, C; Wang, J; Zhang, L | 1 |
| De Caro, C; Iannone, LF; Lattanzi, S; Roberti, R; Russo, E; Zaccara, G | 1 |
| Klein, P; Löscher, W | 1 |
| Chung, SS; French, JA; Kamin, M; Krauss, GL; Lee, SK; Maciejowski, M; Rosenfeld, WE; Sperling, MR | 1 |
| Pietrafusa, N; Specchio, N; Vigevano, F | 1 |
| Brandt, C; Klein, P; Krauss, GL; Rosenfeld, WE; Serratosa, JM; Steinhoff, BJ; Toledo, M | 1 |
| Hussar, DA | 1 |
| Abou-Khalil, B; Aboumatar, S; Bhatia, P; Biton, V; Klein, P; Krauss, GL; Rosenfeld, WE; Sperling, MR; Vossler, DG; Wechsler, R | 1 |
| Abou-Khalil, B; Aboumatar, S; Bhatia, P; Biton, V; Ferrari, L; Grall, M; Klein, P; Krauss, GL; Rosenfeld, WE; Sperling, MR; Vossler, DG; Wechsler, R | 1 |
| Huh, KY; Jang, IJ; Kim, YK; Lee, S; Sunwoo, J; Yang, E; Yu, KS | 1 |
| Biton, V; Halford, JJ; Rosenfeld, WE; Sander, JW; Steinhoff, BJ; Toledo, M | 1 |
| Privitera, M; Richy, FF; Schabert, VF | 1 |
| Brigo, F; Del Giovane, C; Lattanzi, S; Russo, E; Silvestrini, M; Striano, P; Trinka, E; Zaccara, G | 1 |
| Elliott, T; Gienapp, AJ; Ridley-Pryor, T; Wheless, JW | 1 |
| Brandt, C; Milanov, I; Sánchez-Álvarez, JC; Serratosa, JM; Steinhoff, BJ | 1 |
| Darpo, B; Kamin, M; Sager, PT; Xue, H | 1 |
| Karkare, S; Kothare, SV; Shah, YD; Varughese, RT | 1 |
| Ferrari, L; Kamin, M; Rosenfeld, WE | 1 |
| Abou-Khalil, B; Aboumatar, S; Klein, P; Krauss, GL; Rosenfeld, WE; Sperling, MR | 1 |
| Ben-Menachem, E; Brandt, C; García Morales, I; Rosenfeld, WE; Santamarina, E; Serratosa, JM; Steinhoff, BJ | 1 |
| Ángel Calleja, M; Gil, A; Navarro, A; Serratosa, JM; Subías Labazuy, S; Toledo, M; Villanueva, V | 1 |
| Aboumatar, S; Biton, V; Ferrari, L; Rosenfeld, WE; Wechsler, R | 1 |
| Charlier, B; Coglianese, A; Coppola, G; Dal Piaz, F; de Grazia, U; Filippelli, A; Izzo, V; Menna, P; Operto, FF | 1 |
| Abou-Khalil, B; Osborn, M | 1 |
| Fornari Caprara, AL; Rissardo, JP | 1 |
22 review(s) available for 2,3,4,6-tetrachlorophenol and carbamates
| Article | Year |
|---|---|
Non-Hodgkin lymphoma and pesticide exposure: 25 years of research.
Topics: Agricultural Workers' Diseases; Carbamates; Chlorophenols; Herbicides; Humans; Hydrocarbons, Chlorinated; Insecticides; Lymphoma, Non-Hodgkin; Occupational Exposure; Pesticides; Phenoxyacetates; Triazines; United States | 2006 |
Cenobamate: First Approval.
Topics: Administration, Oral; Adult; Anticonvulsants; Carbamates; Chlorophenols; Drug Approval; Epilepsies, Partial; Epilepsy; Humans; Tetrazoles | 2020 |
Cenobamate for the treatment of focal epilepsies.
Topics: Animals; Anticonvulsants; Carbamates; Chlorophenols; Epilepsies, Partial; Headache; Humans; Randomized Controlled Trials as Topic; Tetrazoles; Treatment Outcome | 2020 |
Adjunctive Cenobamate for Focal-Onset Seizures in Adults: A Systematic Review and Meta-Analysis.
Topics: Adult; Anticonvulsants; Carbamates; Chlorophenols; Drug Therapy, Combination; Epilepsy; Humans; Randomized Controlled Trials as Topic; Seizures; Tetrazoles; Treatment Outcome | 2020 |
Cenobamate (Xcopri) for focal seizures.
Topics: Anticonvulsants; Carbamates; Chlorophenols; Clinical Trials as Topic; Drug Therapy, Combination; Humans; Seizures; Tetrazoles | 2020 |
Pharmacological treatment of focal epilepsy in adults: an evidence based approach.
Topics: Adult; Anticonvulsants; Carbamates; Chlorophenols; Epilepsies, Partial; Humans; Tetrazoles | 2021 |
[Cenobamate-a new perspective for epilepsy treatment].
Topics: Anticonvulsants; Carbamates; Chlorophenols; Epilepsy; Humans; Seizures; Tetrazoles | 2021 |
Adjunctive cenobamate for the treatment of focal onset seizures in adults with epilepsy: a critical review.
Topics: Adult; Animals; Anticonvulsants; Carbamates; Chlorophenols; Drug Resistant Epilepsy; Humans; Tetrazoles | 2020 |
Cenobamate (XCOPRI): Can preclinical and clinical evidence provide insight into its mechanism of action?
Topics: Animals; Anticonvulsants; Carbamates; Chlorophenols; Drug Evaluation, Preclinical; Humans; Randomized Controlled Trials as Topic; Seizures; Tetrazoles | 2020 |
New Methods Used in Pharmacokinetics and Therapeutic Monitoring of the First and Newer Generations of Antiepileptic Drugs (AEDs).
Topics: Anticonvulsants; Carbamates; Chlorophenols; Drug Monitoring; Humans; Seizures; Tetrazoles | 2020 |
Cenobamate: Neuroprotective Potential of a New Antiepileptic Drug.
Topics: Animals; Carbamates; Central Nervous System Diseases; Chlorophenols; Drug Repositioning; GABA-A Receptor Agonists; Glutamic Acid; Humans; Neuroprotective Agents; Signal Transduction; Tetrazoles; Voltage-Gated Sodium Channel Blockers | 2021 |
Cenobamate tablets as a treatment for focal-onset seizures in adults.
Topics: Adult; Animals; Anticonvulsants; Carbamates; Chlorophenols; Epilepsies, Partial; Humans; Randomized Controlled Trials as Topic; Tablets; Tetrazoles | 2021 |
The ups and downs of alkyl-carbamates in epilepsy therapy: How does cenobamate differ?
Topics: Anticonvulsants; Carbamates; Chlorophenols; Epilepsy; Humans; Tetrazoles; Treatment Outcome | 2021 |
Anti-seizure medications and efficacy against focal to bilateral tonic-clonic seizures: A systematic review with relevance for SUDEP prevention.
Topics: Anticonvulsants; Carbamates; Chlorophenols; Epilepsy, Tonic-Clonic; Humans; Seizures; Sudden Unexpected Death in Epilepsy; Tetrazoles | 2021 |
Efficacy and safety of cenobamate in patients with uncontrolled focal seizures: A meta-analysis.
Topics: Anticonvulsants; Carbamates; Chlorophenols; Dizziness; Dose-Response Relationship, Drug; Drug Resistant Epilepsy; Fatigue; Humans; Nausea; Randomized Controlled Trials as Topic; Seizures; Tetrazoles; Treatment Outcome; Vertigo | 2021 |
Pharmacology of Cenobamate: Mechanism of Action, Pharmacokinetics, Drug-Drug Interactions and Tolerability.
Topics: Adult; Animals; Anticonvulsants; Biological Availability; Carbamates; Chlorophenols; Dose-Response Relationship, Drug; Drug Interactions; Epilepsies, Partial; Humans; Randomized Controlled Trials as Topic; Tetrazoles | 2021 |
The Pharmacology and Clinical Efficacy of Antiseizure Medications: From Bromide Salts to Cenobamate and Beyond.
Topics: Animals; Anticonvulsants; Bromides; Carbamates; Chlorophenols; Drug Therapy, Combination; Epilepsy; Humans; Salts; Seizures; Tetrazoles; Treatment Outcome | 2021 |
Is Cenobamate the Breakthrough We Have Been Wishing for?
Topics: Anticonvulsants; Carbamates; Chlorophenols; Epilepsy; Humans; Seizures; Tetrazoles | 2021 |
Practical guidance for the management of adults receiving adjunctive cenobamate for the treatment of focal epilepsy-expert opinion.
Topics: Adult; Anticonvulsants; Carbamates; Chlorophenols; Drug Therapy, Combination; Epilepsies, Partial; Expert Testimony; Humans; Tetrazoles | 2021 |
Indirect treatment comparison of cenobamate to other ASMs for the treatment of uncontrolled focal seizures.
Topics: Adult; Anticonvulsants; Carbamates; Chlorophenols; Double-Blind Method; Drug Therapy, Combination; Humans; Randomized Controlled Trials as Topic; Seizures; Tetrazoles; Treatment Outcome | 2022 |
Third-Generation Antiseizure Medications for Adjunctive Treatment of Focal-Onset Seizures in Adults: A Systematic Review and Network Meta-analysis.
Topics: Adult; Anticonvulsants; Carbamates; Chlorophenols; Dibenzazepines; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Lacosamide; Male; Middle Aged; Network Meta-Analysis; Nitriles; Pyridones; Pyrrolidinones; Randomized Controlled Trials as Topic; Seizures; Tetrazoles | 2022 |
Cenobamate (YKP3089) and Drug-Resistant Epilepsy: A Review of the Literature.
Topics: Animals; Carbamates; Chlorophenols; Drug Resistant Epilepsy; Seizures; Tetrazoles; United States | 2023 |
13 trial(s) available for 2,3,4,6-tetrachlorophenol and carbamates
| Article | Year |
|---|---|
Suppression of the photoparoxysmal response in photosensitive epilepsy with cenobamate (YKP3089).
Topics: Adolescent; Adult; Anticonvulsants; Area Under Curve; Carbamates; Chlorophenols; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy, Reflex; Female; Humans; Male; Photic Stimulation; Single-Blind Method; Tetrazoles; Young Adult | 2019 |
Mass Balance, Metabolism, and Excretion of Cenobamate, a New Antiepileptic Drug, After a Single Oral Administration in Healthy Male Subjects.
Topics: Administration, Oral; Adult; Anticonvulsants; Biotransformation; Carbamates; Chlorophenols; Gastrointestinal Absorption; Healthy Volunteers; Humans; Intestinal Elimination; Male; Metabolomics; Middle Aged; New Jersey; Renal Elimination; Tetrazoles; Young Adult | 2020 |
Cenobamate (YKP3089) as adjunctive treatment for uncontrolled focal seizures in a large, phase 3, multicenter, open-label safety study.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamates; Chlorophenols; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Seizures; Tetrazoles; Treatment Outcome; Young Adult | 2020 |
Randomized phase 2 study of adjunctive cenobamate in patients with uncontrolled focal seizures.
Topics: Adolescent; Adult; Anticonvulsants; Carbamates; Chlorophenols; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Seizures; Tetrazoles; Young Adult | 2020 |
Cenobamate treatment of focal-onset seizures: Quality of life and outcome during up to eight years of treatment.
Topics: Adolescent; Adult; Anticonvulsants; Carbamates; Chlorophenols; Humans; Quality of Life; Seizures; Tetrazoles; Treatment Outcome | 2021 |
Efficacy of adjunctive cenobamate based on number of concomitant antiseizure medications, seizure frequency, and epilepsy duration at baseline: A post-hoc analysis of a randomized clinical study.
Topics: Adult; Anticonvulsants; Carbamates; Chlorophenols; Double-Blind Method; Drug Therapy, Combination; Epilepsy; Humans; Seizures; Tetrazoles; Treatment Outcome | 2021 |
Long-term safety of adjunctive cenobamate in patients with uncontrolled focal seizures: Open-label extension of a randomized clinical study.
Topics: Anticonvulsants; Carbamates; Chlorophenols; Double-Blind Method; Drug Therapy, Combination; Humans; Seizures; Tetrazoles; Treatment Outcome | 2021 |
Pharmacokinetics and safety of cenobamate, a novel antiseizure medication, in healthy Japanese, and an ethnic comparison with healthy non-Japanese.
Topics: Carbamates; Chlorophenols; Dose-Response Relationship, Drug; Double-Blind Method; Healthy Volunteers; Humans; Japan; Tetrazoles | 2022 |
Long-term individual retention with cenobamate in adults with focal seizures: Pooled data from the clinical development program.
Topics: Adult; Anticonvulsants; Carbamates; Chlorophenols; Double-Blind Method; Drug Therapy, Combination; Humans; Seizures; Tetrazoles; Treatment Outcome | 2022 |
Efficacy and safety of adjunctive cenobamate: Post-hoc analysis of study C017 in patients grouped by mechanism of action of concomitant antiseizure medications.
Topics: Anticonvulsants; Carbamates; Chlorophenols; Double-Blind Method; Drug Therapy, Combination; Humans; Tetrazoles; Treatment Outcome | 2022 |
A Phase 1 Clinical Study Evaluating the Effects of Cenobamate on the QT Interval.
Topics: Adult; Carbamates; Chlorophenols; Double-Blind Method; Humans; Long QT Syndrome; Tetrazoles | 2022 |
Onset of efficacy and adverse events during Cenobamate titration period.
Topics: Adult; Anticonvulsants; Carbamates; Chlorophenols; Drug Therapy, Combination; Epilepsies, Partial; Humans; Quality of Life; Seizures; Tetrazoles; Treatment Outcome | 2022 |
Post hoc analysis of a phase 3 study for treatment of uncontrolled focal seizures: Adjunctive cenobamate dose and seizure reduction by baseline seizure frequency.
Topics: Anticonvulsants; Carbamates; Chlorophenols; Double-Blind Method; Drug Therapy, Combination; Humans; Seizures; Tetrazoles; Treatment Outcome | 2022 |
20 other study(ies) available for 2,3,4,6-tetrachlorophenol and carbamates
| Article | Year |
|---|---|
[Pularyl in the control of common external parasites in domestic animals].
Topics: Animals; Animals, Domestic; Carbamates; Cats; Cattle; Chickens; Chlorophenols; Dogs; Drug Combinations; Drug Evaluation; Ectoparasitic Infestations; Methods; Naphthalenes; Polychlorinated Biphenyls; Swine | 1975 |
Biological monitoring of agricultural workers exposed to pesticides: II. Monitoring of intact pesticides and their metabolites.
Topics: Agricultural Workers' Diseases; Aniline Compounds; Carbamates; Chlorophenols; Chlorphenamidine; Environmental Exposure; Herbicides; Humans; Hydrocarbons, Brominated; Insecticides; Nitrophenols; Organophosphorus Compounds; Pesticides | 1986 |
Evaluation of exposure to organophosphate, carbamate, phenoxy acid, and chlorophenol pesticides in pregnant women from 10 Caribbean countries.
Topics: Adult; Carbamates; Caribbean Region; Chlorophenols; Environmental Monitoring; Environmental Pollutants; Female; Humans; Maternal Exposure; Organophosphorus Compounds; Pesticides; Pregnancy | 2015 |
Investigation of salicylanilide and 4-chlorophenol-based N-monosubstituted carbamates as potential inhibitors of acetyl- and butyrylcholinesterase.
Topics: Acetylcholinesterase; Animals; Butyrylcholinesterase; Carbamates; Chlorophenols; Cholinesterase Inhibitors; Electrophorus; Horses; Inhibitory Concentration 50; Salicylanilides; Structure-Activity Relationship | 2018 |
New Treatment for Partial-Onset Seizures in Adults.
Topics: Adult; Anticonvulsants; Carbamates; Chlorophenols; Drug Approval; Epilepsies, Partial; Humans; Tetrazoles; United States; United States Food and Drug Administration | 2020 |
Pharmacokinetics of Cenobamate: Results From Single and Multiple Oral Ascending-Dose Studies in Healthy Subjects.
Topics: Administration, Oral; Adolescent; Adult; Anticonvulsants; Area Under Curve; Carbamates; Chlorophenols; Clinical Trials, Phase I as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Female; Half-Life; Humans; Male; Middle Aged; Randomized Controlled Trials as Topic; Tetrazoles; Young Adult | 2020 |
Cenobamate for the treatment of focal epilepsy.
Topics: Adult; Anticonvulsants; Carbamates; Chlorophenols; Epilepsies, Partial; Humans; Seizures; Tetrazoles | 2020 |
Positive allosteric modulation of GABA
Topics: Animals; Anticonvulsants; CA1 Region, Hippocampal; CA3 Region, Hippocampal; Carbamates; Chlorophenols; Female; HEK293 Cells; Humans; Male; Neurons; Rats, Sprague-Dawley; Rats, Wistar; Receptors, GABA-A; Tetrazoles | 2020 |
An Ex Vivo Evaluation of Cenobamate Administered via Enteral Tubes.
Topics: Administration, Oral; Anticonvulsants; Carbamates; Chlorophenols; Enteral Nutrition; Humans; Seizures; Tablets; Tetrazoles | 2020 |
Cenobamate: A New Adjunctive Agent for Drug-Resistant Focal Onset Epilepsy.
Topics: Adolescent; Adult; Aged; Animals; Anticonvulsants; Carbamates; Chemotherapy, Adjuvant; Chlorophenols; Epilepsies, Partial; Female; Humans; Male; Middle Aged; Quality of Life; Rats; Tetrazoles; Young Adult | 2021 |
New Drugs 2021, Part 2.
Topics: Adenosine Monophosphate; Alanine; Amisulpride; Carbamates; Cefiderocol; Cephalosporins; Chlorophenols; COVID-19 Drug Treatment; Drug Approval; Drug Combinations; Fumarates; Humans; Indans; Organophosphates; Oxadiazoles; Piperazines; Spiro Compounds; Tetrazoles; Thiophenes; Tromethamine; United States; United States Food and Drug Administration | 2021 |
Post hoc analysis of a phase 3, multicenter, open-label study of cenobamate for treatment of uncontrolled focal seizures: Effects of dose adjustments of concomitant antiseizure medications.
Topics: Anticonvulsants; Carbamates; Chlorophenols; Double-Blind Method; Drug Therapy, Combination; Humans; Seizures; Tetrazoles; Treatment Outcome | 2021 |
Efficacy of cenobamate for uncontrolled focal seizures: Post hoc analysis of a Phase 3, multicenter, open-label study.
Topics: Adult; Anticonvulsants; Carbamates; Chlorophenols; Double-Blind Method; Drug Therapy, Combination; Humans; Seizures; Tetrazoles; Treatment Outcome | 2021 |
Initial Real-World Experience With Cenobamate in Adolescents and Adults: A Single Center Experience.
Topics: Adolescent; Anticonvulsants; Carbamates; Chlorophenols; Double-Blind Method; Drug-Related Side Effects and Adverse Reactions; Exanthema; Humans; Retrospective Studies; Seizures; Tetrazoles; Treatment Outcome; Young Adult | 2022 |
Adjunctive use of cenobamate for pediatric refractory focal-onset epilepsy: A single-center retrospective study.
Topics: Adolescent; Adult; Anticonvulsants; Carbamates; Child; Chlorophenols; Drug Resistant Epilepsy; Epilepsies, Partial; Epilepsy; Humans; Retrospective Studies; Seizures; Tetrazoles; Treatment Outcome | 2022 |
Efficacy of cenobamate by focal seizure subtypes: Post-hoc analysis of a phase 3, multicenter, open-label study.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Caffeine; Carbamates; Chlorophenols; Double-Blind Method; Drug Therapy, Combination; Humans; Middle Aged; Seizures; Tetrazoles; Treatment Outcome; Young Adult | 2022 |
Efficacy of cenobamate for uncontrolled focal seizures in patients with previous epilepsy-related surgery: Post hoc analysis of a phase 3, multicenter, open-label study.
Topics: Anticonvulsants; Carbamates; Chlorophenols; Double-Blind Method; Drug Therapy, Combination; Epilepsy; Humans; Seizures; Tetrazoles; Treatment Outcome | 2022 |
Determination of the economically justifiable price of cenobamate in the treatment of focal-onset seizures in adult patients with drug-resistant epilepsy in Spain.
Topics: Adult; Carbamates; Chlorophenols; Cost-Benefit Analysis; Epilepsy; Humans; Lacosamide; Quality-Adjusted Life Years; Spain; Tetrazoles | 2022 |
Development and Validation of a UHPLC-MS/MS-Based Method to Quantify Cenobamate in Human Plasma Samples.
Topics: Carbamates; Chlorophenols; Chromatography, High Pressure Liquid; Humans; Seizures; Tandem Mass Spectrometry | 2022 |
The cenobamate-clobazam interaction- evidence of synergy in addition to pharmacokinetic interaction.
Topics: Anticonvulsants; Benzodiazepines; Carbamates; Chlorophenols; Clobazam; Humans | 2023 |