Compounds > 2'3'-didehydro-2'3'-dideoxyadenosine
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2'3'-didehydro-2'3'-dideoxyadenosine and zidovudine

2'3'-didehydro-2'3'-dideoxyadenosine has been researched along with zidovudine in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19902 (40.00)18.7374
1990's1 (20.00)18.2507
2000's1 (20.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Baba, M; Balzarini, J; Broder, S; De Clercq, E; Herdewijn, P; Pauwels, R; Vanderhaeghe, H1
Baba, M; Balzarini, J; De Clercq, E; Herdewijn, P; Pauwels, R1
Balzarini, J; De Clercq, E; Knispel, T; Meier, C1
Chong, Y; Chu, CK; Gumina, G; Schinazi, RF; Wang, J; Zhou, W1
Gangadhara, KL; Herdewijn, P; Lescrinier, E; Pannecouque, C1

Other Studies

5 other study(ies) available for 2'3'-didehydro-2'3'-dideoxyadenosine and zidovudine

ArticleYear
3'-substituted 2',3'-dideoxynucleoside analogues as potential anti-HIV (HTLV-III/LAV) agents.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:8

    Topics: Antiviral Agents; Cell Line; Chemical Phenomena; Chemistry; Cytopathogenic Effect, Viral; Deoxyribonucleosides; HIV; Humans; Structure-Activity Relationship; T-Lymphocytes; Virus Replication

1987
Synthesis and anti-HIV activity of various 2'- and 3'-substituted 2',3'-dideoxyadenosines: a structure-activity analysis.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:11

    Topics: Antiviral Agents; Deoxyadenosines; Dideoxyadenosine; HIV; Structure-Activity Relationship

1987
cycloSal-Pronucleotides of 2',3'-dideoxyadenosine and 2', 3'-dideoxy-2',3'-didehydroadenosine: synthesis and antiviral evaluation of a highly efficient nucleotide delivery system.
    Journal of medicinal chemistry, 1999, May-06, Volume: 42, Issue:9

    Topics: 3T3 Cells; Adenosine Deaminase; Adenosine Monophosphate; AMP Deaminase; Animals; Anti-HIV Agents; Cell Line; Cell Transformation, Viral; Deoxyadenine Nucleotides; Dideoxynucleotides; Drug Delivery Systems; Drug Evaluation, Preclinical; HIV-1; HIV-2; Humans; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Mice; Organophosphates; Prodrugs; Structure-Activity Relationship; Virus Replication

1999
Synthesis, structure-activity relationships, and drug resistance of beta-d-3'-fluoro-2',3'-unsaturated nucleosides as anti-HIV Agents.
    Journal of medicinal chemistry, 2004, Jun-17, Volume: 47, Issue:13

    Topics: Anti-HIV Agents; Drug Resistance, Viral; Drug Stability; HIV-1; Humans; In Vitro Techniques; Leukocytes, Mononuclear; Models, Molecular; Molecular Conformation; Nucleosides; Structure-Activity Relationship

2004
Hydroxy fatty acids for the delivery of dideoxynucleosides as anti-HIV agents.
    Bioorganic & medicinal chemistry letters, 2014, Feb-01, Volume: 24, Issue:3

    Topics: Adenine; Anti-HIV Agents; Antiviral Agents; Dideoxynucleosides; Drug Delivery Systems; Fatty Acids; HIV-1; Humans; Hydroxy Acids; Molecular Structure; Prodrugs

2014