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2,2-dichloro-1,1,1-trifluoroethane and phenobarbital

2,2-dichloro-1,1,1-trifluoroethane has been researched along with phenobarbital in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (75.00)18.2507
2000's1 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Aeschlimann, D; Christen, U; Gut, J; Huwyler, J1
Baker, MT; Olson, MJ; Wang, Y1
Ferrara, R; King, LJ; Manno, M; Tolando, R1
Bortolato, S; Ferrara, R; Manno, M; Tolando, R; White, IN; Zanovello, A1

Other Studies

4 other study(ies) available for 2,2-dichloro-1,1,1-trifluoroethane and phenobarbital

ArticleYear
The kidney as a novel target tissue for protein adduct formation associated with metabolism of halothane and the candidate chlorofluorocarbon replacement 2,2-dichloro-1,1,1-trifluoroethane.
    European journal of biochemistry, 1992, Jul-01, Volume: 207, Issue:1

    Topics: Animals; Cell Fractionation; Chlorofluorocarbons; Chlorofluorocarbons, Ethane; Chlorofluorocarbons, Methane; Halothane; Hydrocarbons, Halogenated; Kidney; Liver; Male; Microsomes; Microsomes, Liver; Phenobarbital; Protein Binding; Proteins; Rats; Rats, Inbred Strains

1992
Interaction of fluoroethane chlorofluorocarbon (CFC) substitutes with microsomal cytochrome P450. Stimulation of P450 activity and chlorodifluoroethene metabolism.
    Biochemical pharmacology, 1993, Jul-06, Volume: 46, Issue:1

    Topics: Animals; Chlorofluorocarbons; Chlorofluorocarbons, Ethane; Cytochrome P-450 Enzyme System; Halothane; Hydrocarbons, Fluorinated; Male; Microsomes, Liver; NADP; Oxygen Consumption; Phenobarbital; Rabbits; Solubility

1993
Cytochrome P450 inactivation during reductive metabolism of 1,1-dichloro-2,2,2-trifluoroethane (HCFC-123) by phenobarbital- and pyridine-induced rat liver microsomes.
    Toxicology and applied pharmacology, 1997, Volume: 143, Issue:2

    Topics: Animals; Chlorofluorocarbons; Chlorofluorocarbons, Ethane; Cytochrome b Group; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP2E1 Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Free Radicals; Gas Chromatography-Mass Spectrometry; Glutathione; Isoenzymes; Male; Microsomes, Liver; Oxidation-Reduction; Phenobarbital; Pyridines; Rats; Rats, Wistar; Time Factors

1997
Bioactivation and toxicity in vitro of HCFC-123 and HCFC-141b: role of cytochrome P450.
    Toxicology letters, 2001, Oct-15, Volume: 124, Issue:1-3

    Topics: Animals; Biotransformation; Chlorofluorocarbons; Chlorofluorocarbons, Ethane; Cytochrome P-450 Enzyme System; Excitatory Amino Acid Antagonists; Free Radicals; Glutathione; Hepatocytes; L-Lactate Dehydrogenase; Male; Microsomes, Liver; Phenobarbital; Pyridines; Rats; Rats, Wistar

2001