Compounds > 2,2-dichloro-1,1,1-trifluoroethane
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2,2-dichloro-1,1,1-trifluoroethane and halothane

2,2-dichloro-1,1,1-trifluoroethane has been researched along with halothane in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (55.56)18.2507
2000's4 (44.44)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gut, J; Huwyler, J1
Aeschlimann, D; Christen, U; Gut, J; Huwyler, J1
Baker, MT; Olson, MJ; Wang, Y1
Fisher, JW; Jarabek, AM; McDougal, JN; Vinegar, A; Williams, RJ1
Brock, WJ; Cook, JC; Keller, DA; Lieder, PH1
Bortolato, S; Ferrara, R; Manno, M; White, IN; Zanovello, A1
De Matteis, F; Gervasi, PG; Longo, V; Marini, S; Zaccaro, C1
Bortolato, S; Brotto, M; Gervasi, PG; Manno, M; Marini, S; Rugge, M; Zanovello, A1
Ferrara, R; Manno, M; Zanovello, A1

Other Studies

9 other study(ies) available for 2,2-dichloro-1,1,1-trifluoroethane and halothane

ArticleYear
Exposure to the chlorofluorocarbon substitute 2,2-dichloro-1,1,1- trifluoroethane and the anesthetic agent halothane is associated with transient protein adduct formation in the heart.
    Biochemical and biophysical research communications, 1992, May-15, Volume: 184, Issue:3

    Topics: Animals; Antibodies; Biotransformation; Chlorofluorocarbons; Chlorofluorocarbons, Ethane; Chlorofluorocarbons, Methane; Chromatography, Affinity; Electrophoresis, Polyacrylamide Gel; Halothane; Hydrocarbons, Halogenated; Immunoblotting; Male; Myocardium; Protein Binding; Proteins; Rats; Rats, Inbred Strains

1992
The kidney as a novel target tissue for protein adduct formation associated with metabolism of halothane and the candidate chlorofluorocarbon replacement 2,2-dichloro-1,1,1-trifluoroethane.
    European journal of biochemistry, 1992, Jul-01, Volume: 207, Issue:1

    Topics: Animals; Cell Fractionation; Chlorofluorocarbons; Chlorofluorocarbons, Ethane; Chlorofluorocarbons, Methane; Halothane; Hydrocarbons, Halogenated; Kidney; Liver; Male; Microsomes; Microsomes, Liver; Phenobarbital; Protein Binding; Proteins; Rats; Rats, Inbred Strains

1992
Interaction of fluoroethane chlorofluorocarbon (CFC) substitutes with microsomal cytochrome P450. Stimulation of P450 activity and chlorodifluoroethene metabolism.
    Biochemical pharmacology, 1993, Jul-06, Volume: 46, Issue:1

    Topics: Animals; Chlorofluorocarbons; Chlorofluorocarbons, Ethane; Cytochrome P-450 Enzyme System; Halothane; Hydrocarbons, Fluorinated; Male; Microsomes, Liver; NADP; Oxygen Consumption; Phenobarbital; Rabbits; Solubility

1993
Rat to human extrapolation of HCFC-123 kinetics deduced from halothane kinetics: a corollary approach to physiologically based pharmacokinetic modeling.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1996, Volume: 30, Issue:1

    Topics: Animals; Chlorofluorocarbons; Chlorofluorocarbons, Ethane; Halothane; Humans; Male; Models, Biological; Rats; Rats, Inbred F344; Species Specificity; Trifluoroacetic Acid

1996
1,1,1-Trifluoro-2,2-dichloroethane (HCFC-123) and 1,1,1-trifluoro-2-bromo-2-chloroethane (halothane) cause similar biochemical effects in rats exposed by inhalation for five days.
    Drug and chemical toxicology, 1998, Volume: 21, Issue:4

    Topics: Administration, Inhalation; Anesthesia; Animals; Chlorofluorocarbons; Chlorofluorocarbons, Ethane; Cholesterol; Cholesterol, HDL; Cytochrome P-450 Enzyme System; Depression, Chemical; Halothane; Liver; Liver Function Tests; Male; Organ Size; Peroxisome Proliferators; Rats; Triglycerides; Weight Gain

1998
Bioactivation and cytotoxicity of 1,1-dichloro-2,2,2-trifluoroethane (HCFC-123) in isolated rat hepatocytes.
    Pharmacology & toxicology, 2001, Volume: 88, Issue:4

    Topics: Animals; Chlorofluorocarbons; Chlorofluorocarbons, Ethane; Cyclic N-Oxides; Dose-Response Relationship, Drug; Fomepizole; Gas Chromatography-Mass Spectrometry; Glutathione; Halothane; Hepatocytes; In Vitro Techniques; Ketones; L-Lactate Dehydrogenase; Male; Maleates; Nitrogen Oxides; Pyrazoles; Pyridines; Rats; Rats, Wistar; Troleandomycin

2001
Selective inactivation of rat and bovine olfactory cytochrome P450 by three haloethanes.
    Toxicology letters, 2001, Oct-15, Volume: 124, Issue:1-3

    Topics: Anesthetics, Inhalation; Animals; Catalysis; Cattle; Chlorofluorocarbons; Chlorofluorocarbons, Ethane; Cytochrome P-450 Enzyme System; Halothane; Isoenzymes; Male; Microsomes, Liver; Nose; Rats; Rats, Sprague-Dawley

2001
Trifluoroacetylated proteins in liver and plasma of guinea pigs treated with HCFC-123 and halothane.
    Toxicology letters, 2003, Sep-15, Volume: 144, Issue:1

    Topics: Alanine Transaminase; Anesthetics, Inhalation; Animals; Aspartate Aminotransferases; Azo Compounds; Biomarkers; Chemical and Drug Induced Liver Injury; Chlorofluorocarbons; Chlorofluorocarbons, Ethane; Coloring Agents; Creatine Kinase; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Guinea Pigs; Halothane; Immunoblotting; Liver; Male; Proteins; Trifluoroacetic Acid

2003
Reductive activation of HCFC-123 by methaemalbumin.
    Toxicology letters, 2003, Sep-15, Volume: 144, Issue:1

    Topics: Anaerobiosis; Anesthetics, Inhalation; Animals; Biotransformation; Chlorofluorocarbons; Chlorofluorocarbons, Ethane; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; Fluorides; Free Radicals; Halothane; Heme; Humans; Methemalbumin; Microsomes, Liver; Oxidation-Reduction; Rats

2003