2,2,2-trichloroethanol has been researched along with trichloroethylene in 58 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 22 (37.93) | 18.7374 |
| 1990's | 12 (20.69) | 18.2507 |
| 2000's | 14 (24.14) | 29.6817 |
| 2010's | 8 (13.79) | 24.3611 |
| 2020's | 2 (3.45) | 2.80 |
| Authors | Studies |
|---|---|
| Crippen, GM; Ghose, AK | 1 |
| Gorczak, J; Krasts, M; Vesterberg, O | 2 |
| Ageishi, Y; Kobayashi, M; Nakayama, H; Takahashi, M; Takano, T | 1 |
| Buben, JA; O'Flaherty, EJ | 1 |
| Hobara, T; Iwamoto, S; Kawamoto, T; Kobayashi, H; Sakai, T | 1 |
| Hobara, T; Imamura, A; Iwamoto, S; Kawamoto, T; Kobayashi, H; Koshiro, A; Sakai, T | 1 |
| Lowry, LK | 1 |
| Aitio, A; Pekari, K | 1 |
| Carlson, GP; White, JF | 1 |
| Higashihara, E; Hobara, T; Kawamoto, T; Kobayashi, H; Sakai, T | 1 |
| Fujita, H; Ikeda, M; Koizumi, A; Kumai, M; Sadamoto, T; Yamamoto, M | 1 |
| Chmara, D; Faure, J; Gu, ZW; Jalbert, P; Marka, C; Sele, B; Vincent, F; Vincent, M | 1 |
| Fentiman, AF; Leighty, EG | 1 |
| Crovato, E; Re, MR | 1 |
| Burback, BL; Perry, JJ; Vanderberg, LA | 1 |
| Brodeur, J; Laparé, S; Tardif, R | 1 |
| Fukabori, S; Hara, K; Nakaaki, K; Yamamura, Y; Yoshida, K; Yoshida, M; Yuasa, H | 1 |
| Bull, RJ; Merdink, JL; Springer, DL; Stenner, RD; Stevens, DK | 1 |
| Foster, JR; Green, T; Mainwaring, GW | 1 |
| Abbas, R; Fisher, JW | 1 |
| Simon, TW | 1 |
| Elfarra, AA; Krause, RJ; Lash, LH; Last, AR; Parker, JC | 1 |
| Dawson, BV; Goldberg, SJ; Johnson, PD | 1 |
| Bull, RJ; Gonzalez-Leon, A; Merdink, JL; Schultz, IR | 1 |
| Abbas, R; Fisher, JW; Mahle, D | 1 |
| Burton, GA; Fisher, JW; Greenberg, MS | 1 |
| Blaszkewicz, M; Bolt, HM; Brüning, T; De Smet, K; Rogiers, V; Vercruysse, A | 1 |
| Bloemen, LJ; Commandeur, JN; Kezic, S; Monster, AC; Vermeulen, NP; Veulemans, H; Wilmer, JW | 1 |
| Doty, SL; Gordon, MP; Howald, WN; Shang, TQ; Wilson, AM | 1 |
| Brüning, T; Fels, LM; Fricke, HH; Mensing, T; Voss, B; Welge, P; Wilhelm, M | 1 |
| Forkert, PG; Lash, LH; Nadeau, V; Simmonds, A; Tardif, R | 1 |
| Deng, YY; Huang, JX; Li, LY; Tang, XJ | 1 |
| Dow, J; Foster, J; Green, T | 1 |
| MARSHALL, EK; OWENS, AH | 1 |
| STYBLOVA, V; TEISINGER, J; VLACHOVA, D | 1 |
| VLACHOVA, D | 1 |
| MEDEK, V | 1 |
| MIKISKA, A; MIKISKOVA, H | 1 |
| KULESZA, K | 1 |
| MIKISKOVA, H | 1 |
| Anupriwan, A; Forkert, PG; Leader, A; Tanphaichitr, N; Vincent, R; Wade, MG; Weerachatyanukul, W; Xu, H | 1 |
| Igisu, H; Narimatsu, H | 1 |
| Anand, SS; Mehendale, HM; Mumtaz, MM | 1 |
| Bronley-DeLancey, A; Hoel, DG; Jollow, DJ; McMillan, DC; McMillan, JM; Mohr, LC | 1 |
| Chiu, WA; Clewell, HJ; Hack, CE; Jay Zhao, Q | 1 |
| Bartolucci, GB; Carrieri, M; Magosso, D; Piccoli, P; Trevisan, A; Zanetti, E | 1 |
| Adinarayana Reddy, C; Caminal, G; Gabarrell, X; Marco-Urrea, E; Parella, T; Vicent, T | 1 |
| Bin, P; Dai, Y; Dong, H; Duan, H; Liu, Q; Niu, Y; Yang, H; Zang, D; Zheng, Y | 1 |
| Evans, AR; Lock, EA; Yaqoob, N | 1 |
| Chandra, A; Chauhan, LK; Goel, SK; Varshney, M | 1 |
| Hibino, Y; Huang, H; Huang, Y; Ito, Y; Jia, X; Kamijima, M; Li, H; Liu, L; Naito, H; Nakajima, T; Song, X; Wang, D; Wang, H; Zhao, N | 1 |
| Evans, A; Foster, JR; Lock, EA; Yaqoob, N | 1 |
| Ball, LM; Bodnar, WM; Bradford, BU; Collins, LB; Gold, A; Kosyk, O; Rusyn, I; Shymonyak, S; Uehara, T; Yoo, HS | 2 |
| Charest-Tardif, G; Haddad, S; Rouhou, MC | 1 |
| Cai, T; Huang, H; Huang, Y; Ito, Y; Kamijima, M; Li, H; Liu, L; Lu, F; Naito, H; Nakajima, T; Song, X; Wang, H; Zhao, N | 1 |
| Dai, Y; Duan, H; Jiao, B; Liu, S; Niu, Y; Shen, M; Yi, M | 1 |
1 review(s) available for 2,2,2-trichloroethanol and trichloroethylene
| Article | Year |
|---|---|
[Trichloroacetic acid and trichloroethanol in urine].
Topics: Biomarkers; Chromatography, Gas; Environmental Exposure; Environmental Monitoring; Ethylene Chlorohydrin; Reference Values; Solvents; Specimen Handling; Tetrachloroethylene; Trichloroacetic Acid; Trichloroethanes; Trichloroethylene | 2004 |
1 trial(s) available for 2,2,2-trichloroethanol and trichloroethylene
| Article | Year |
|---|---|
A human physiologically based pharmacokinetic model for trichloroethylene and its metabolites, trichloroacetic acid and free trichloroethanol.
Topics: Administration, Inhalation; Adult; Ethylene Chlorohydrin; Female; Humans; Male; Models, Biological; Sex Factors; Solvents; Time Factors; Tissue Distribution; Trichloroacetic Acid; Trichloroethylene | 1998 |
56 other study(ies) available for 2,2,2-trichloroethanol and trichloroethylene
| Article | Year |
|---|---|
Use of physicochemical parameters in distance geometry and related three-dimensional quantitative structure-activity relationships: a demonstration using Escherichia coli dihydrofolate reductase inhibitors.
Topics: Binding Sites; Escherichia coli; Folic Acid Antagonists; Models, Molecular; Protein Conformation; Structure-Activity Relationship | 1985 |
Exposure to trichloroethylene II. Metabolites in blood and urine.
Topics: Chlorohydrins; Dose-Response Relationship, Drug; Environmental Exposure; Ethylene Chlorohydrin; Humans; Male; Occupational Medicine; Physical Exertion; Trichloroacetic Acid; Trichloroethylene | 1976 |
Methods for measuring trichloroethanol and trichloroacetic acid in blood and urine after exposure to trichloroethylene.
Topics: Biotransformation; Chlorohydrins; Environmental Exposure; Ethylene Chlorohydrin; Humans; Trichloroacetic Acid; Trichloroethylene | 1975 |
Generalized eruption with severe liver dysfunction associated with occupational exposure to trichloroethylene.
Topics: Adult; Chemical and Drug Induced Liver Injury; Dermatitis, Occupational; Ethylene Chlorohydrin; Humans; Hypersensitivity, Delayed; Japan; Male; Occupational Diseases; Patch Tests; Staphylococcal Infections; Trichloroethylene | 1988 |
Delineation of the role of metabolism in the hepatotoxicity of trichloroethylene and perchloroethylene: a dose-effect study.
Topics: Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Ethylene Chlorohydrin; Glucose-6-Phosphatase; Liver Diseases; Male; Mice; Organ Size; Tetrachloroethylene; Trichloroacetic Acid; Trichloroethylene; Triglycerides | 1985 |
The absorption of trichloroethylene and its metabolites from the urinary bladder of anesthetized dogs.
Topics: Animals; Bile; Chloral Hydrate; Dogs; Dose-Response Relationship, Drug; Ethylene Chlorohydrin; Female; Male; Trichloroacetic Acid; Trichloroethylene; Urinary Bladder | 1988 |
The metabolism of trichloroethylene and its metabolites in the perfused liver.
Topics: Animals; Bile; Chloral Hydrate; Ethylene Chlorohydrin; Liver; Male; Perfusion; Rats; Rats, Inbred Strains; Trichloroacetic Acid; Trichloroethylene | 1987 |
The biological exposure index: its use in assessing chemical exposures in the workplace.
Topics: Acetates; Butanones; Environmental Exposure; Environmental Monitoring; Ethylene Chlorohydrin; Ethylene Glycols; Humans; Industry; Maximum Allowable Concentration; National Institute for Occupational Safety and Health, U.S.; Paint; Trichloroacetic Acid; Trichloroethylene; United States | 1987 |
Determination of 2,2,2-trichloroethanol in urine.
Topics: Air Pollutants, Occupational; Autoanalysis; Chlorohydrins; Chromatography, Gas; Ethylene Chlorohydrin; Humans; Indicators and Reagents; Safety; Trichloroethylene | 1985 |
Cardiac arrhythmogenic action of benzo(a)pyrene in the rabbit.
Topics: Animals; Arrhythmias, Cardiac; Benzo(a)pyrene; Benzopyrenes; Epinephrine; Ethylene Chlorohydrin; Halothane; Male; Methylcholanthrene; Phenobarbital; Rabbits; Time Factors; Trichloroacetic Acid; Trichloroethylene | 1983 |
[Experimental studies of trichloroethylene toxicity. II. Changes in trichloroethylene metabolites in blood serum and in urine during and after exposure to trichloroethylene].
Topics: Animals; Chlorohydrins; Dogs; Environmental Exposure; Ethylene Chlorohydrin; Trichloroacetic Acid; Trichloroethylene | 1983 |
Inhibition of delta-aminolevulinic acid dehydratase by trichloroethylene.
Topics: 5-Aminolevulinate Synthetase; Animals; Bone Marrow; Erythrocytes; Ethylene Chlorohydrin; In Vitro Techniques; Liver; Male; Phenobarbital; Porphobilinogen Synthase; Rats; Rats, Inbred Strains; Trichloroacetic Acid; Trichloroethanes; Trichloroethylene | 1984 |
[Induction of sister chromatide exchange by trichloroethylene and its metabolites (author's transl)].
Topics: Chloral Hydrate; Chlorohydrins; Crossing Over, Genetic; Ethylene Chlorohydrin; Humans; In Vitro Techniques; Mutagenicity Tests; Mutagens; Sister Chromatid Exchange; Trichloroethylene | 1981 |
In vitro conjugation of the trichloroethylene metabolite trichloroethanol to a fatty acid.
Topics: Animals; Chlorohydrins; Coenzyme A; Ethylene Chlorohydrin; Fatty Acids; In Vitro Techniques; Microsomes; Palmitic Acids; Rats; Trichloroethylene | 1981 |
[Percutaneous absorption of trieline with warning levels of the biological indices].
Topics: Air Pollutants, Occupational; Environmental Exposure; Ethylene Chlorohydrin; Humans; Risk; Skin Absorption; Trichloroacetic Acid; Trichloroethylene | 1981 |
Biodegradation of trichloroethylene by Mycobacterium vaccae.
Topics: Biodegradation, Environmental; Ethylene Chlorohydrin; Mycobacterium; Toluene; Trichloroethylene | 1995 |
Effect of various exposure scenarios on the biological monitoring of organic solvents in alveolar air. II. 1,1,1-Trichloroethane and trichloroethylene.
Topics: Adult; Air Pollutants, Occupational; Environmental Monitoring; Ethylene Chlorohydrin; Female; Humans; Male; Middle Aged; Occupational Exposure; Physical Exertion; Pulmonary Alveoli; Solvents; Time Factors; Trichloroacetic Acid; Trichloroethanes; Trichloroethylene | 1995 |
Concentrations of trichloroethylene and its metabolites in blood and urine after acute poisoning by ingestion.
Topics: Accidents, Home; Administration, Oral; Ethylene Chlorohydrin; Humans; Male; Middle Aged; Trichloroacetic Acid; Trichloroethylene | 1996 |
Enterohepatic recirculation of trichloroethanol glucuronide as a significant source of trichloroacetic acid. Metabolites of trichloroethylene.
Topics: Animals; Bile; Chromatography, Gas; Enterohepatic Circulation; Ethylene Chlorohydrin; Glucuronates; Male; Rats; Rats, Inbred F344; Trichloroacetic Acid; Trichloroethylene | 1997 |
Trichloroethylene-induced mouse lung tumors: studies of the mode of action and comparisons between species.
Topics: Administration, Inhalation; Animals; Blotting, Western; Cell Division; Chloral Hydrate; Cytochrome P-450 CYP2E1; Ethylene Chlorohydrin; Female; Glucuronates; Humans; Immunoenzyme Techniques; In Vitro Techniques; Lung; Lung Neoplasms; Male; Mice; Microsomes; Microsomes, Liver; Rats; Rats, Wistar; Solvents; Species Specificity; Trichloroethylene | 1997 |
A physiologically based pharmacokinetic model for trichloroethylene and its metabolites, chloral hydrate, trichloroacetate, dichloroacetate, trichloroethanol, and trichloroethanol glucuronide in B6C3F1 mice.
Topics: Administration, Oral; Animals; Chloral Hydrate; Dichloroacetic Acid; Ethylene Chlorohydrin; Feces; Glucuronates; Liver; Male; Mice; Mice, Inbred Strains; Models, Biological; Solvents; Tissue Distribution; Trichloroacetic Acid; Trichloroethylene | 1997 |
Combining physiologically based pharmacokinetic modeling with Monte Carlo simulation to derive an acute inhalation guidance value for trichloroethylene.
Topics: Administration, Inhalation; Body Fluid Compartments; Computer Simulation; Dose-Response Relationship, Drug; Ethylene Chlorohydrin; Female; Humans; Male; Models, Biological; Monte Carlo Method; Occupational Exposure; Sensitivity and Specificity; Solvents; Trichloroethylene | 1997 |
Species- and sex-related differences in metabolism of trichloroethylene to yield chloral and trichloroethanol in mouse, rat, and human liver microsomes.
Topics: Acetates; Animals; Chloral Hydrate; Dichloroacetic Acid; Ethylene Chlorohydrin; Female; Glyoxylates; Humans; Kinetics; Male; Mice; Microsomes, Liver; NADP; Oxalates; Oxalic Acid; Rats; Rats, Inbred F344; Sex Factors; Solvents; Species Specificity; Trichloroethylene | 1998 |
Cardiac teratogenicity of trichloroethylene metabolites.
Topics: Abnormalities, Drug-Induced; Acetaldehyde; Acetates; Animals; Chloral Hydrate; Cystine; Dichloroethylenes; Embryonic and Fetal Development; Environmental Pollutants; Ethylene Chlorohydrin; Female; Heart; Heart Defects, Congenital; Humans; Maternal Exposure; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Teratogens; Trichloroacetic Acid; Trichloroethylene; Water Pollutants, Chemical; Water Supply | 1998 |
The extent of dichloroacetate formation from trichloroethylene, chloral hydrate, trichloroacetate, and trichloroethanol in B6C3F1 mice.
Topics: Animals; Biological Availability; Chloral Hydrate; Dichloroacetic Acid; Ethylene Chlorohydrin; Half-Life; Male; Metabolic Clearance Rate; Mice; Models, Biological; Trichloroacetic Acid; Trichloroethylene | 1998 |
Physiologically based pharmacokinetic modeling of inhaled trichloroethylene and its oxidative metabolites in B6C3F1 mice.
Topics: Adipose Tissue; Administration, Inhalation; Animals; Chloral Hydrate; Dichloroacetic Acid; Ethylene Chlorohydrin; Kidney; Liver; Lung; Male; Metabolic Clearance Rate; Mice; Mice, Inbred Strains; Models, Biological; Oxidation-Reduction; Sensitivity and Specificity; Solvents; Tissue Distribution; Trichloroacetic Acid; Trichloroethylene | 1999 |
Biotransformation of trichloroethylene in collagen gel sandwich cultures of rat hepatocytes.
Topics: Animals; Animals, Outbred Strains; Biotransformation; Cells, Cultured; Chromatography, Gas; Collagen; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2B1; Cytochrome P-450 CYP2E1; Ethylene Chlorohydrin; Extracellular Matrix; Hepatocytes; Male; Models, Biological; Rats; Rats, Sprague-Dawley; Trichloroacetic Acid; Trichloroethylene | 2000 |
Study on the cytochrome P-450- and glutathione-dependent biotransformation of trichloroethylene in humans.
Topics: Adult; Air Pollutants, Occupational; Biomarkers; Biotransformation; Cytochrome P-450 Enzyme System; Ethylene Chlorohydrin; Glutathione; Humans; Male; Middle Aged; Occupational Exposure; Trichloroacetic Acid; Trichloroethylene | 2001 |
Trichloroethylene oxidative metabolism in plants: the trichloroethanol pathway.
Topics: Ethylene Chlorohydrin; Mass Spectrometry; Nicotiana; Oxidation-Reduction; Trichloroethylene | 2001 |
Renal toxicity after chronic inhalation exposure of rats to trichloroethylene.
Topics: Acetylglucosaminidase; Albuminuria; Animals; Comet Assay; DNA Fragmentation; Ethylene Chlorohydrin; Histocytochemistry; Inhalation Exposure; Kidney Diseases; Male; Rats; Rats, Long-Evans; Trichloroacetic Acid; Trichloroethylene | 2002 |
Metabolism and toxicity of trichloroethylene in epididymis and testis.
Topics: Administration, Inhalation; Animals; Blotting, Western; Chloral Hydrate; Cytochrome P-450 CYP2E1; Epididymis; Ethylene Chlorohydrin; Immunohistochemistry; Male; Mice; Microsomes; Occupational Exposure; Testis; Trichloroacetic Acid; Trichloroethylene | 2002 |
Guinea pig maximization test for trichloroethylene and its metabolites.
Topics: Allergens; Animals; Chloral Hydrate; Dermatitis, Allergic Contact; Dermatitis, Irritant; Ethylene Chlorohydrin; Guinea Pigs; Skin; Toxicity Tests; Trichloroacetic Acid; Trichloroethylene | 2002 |
Increased formic acid excretion and the development of kidney toxicity in rats following chronic dosing with trichloroethanol, a major metabolite of trichloroethylene.
Topics: Acetylglucosamine; Animals; Blood Chemical Analysis; Bromodeoxyuridine; Ethylene Chlorohydrin; Formates; Histocytochemistry; Kidney Diseases; Kidney Neoplasms; Male; Methylmalonic Acid; Random Allocation; Rats; Rats, Inbred F344; Sex Factors; Trichloroethylene | 2003 |
Further studies on the metabolic fate of chloral hydrate and trichloroethanol.
Topics: Biochemical Phenomena; Blood; Chloral Hydrate; Ethanol; Ethylene Chlorohydrin; Humans; Trichloroacetic Acid; Trichloroethylene | 1955 |
[Importance of determination of urinary trichloroethanol in workers exposed to trichloroethylene].
Topics: Ethylene Chlorohydrin; Humans; Trichloroethylene; Urinary Tract; Urine | 1955 |
An easy method for the determination of trichlorethanol in the urine after exposure of trichlorethylene.
Topics: Ethanol; Ethylene Chlorohydrin; Humans; Trichloroethylene | 1957 |
[Relation between the content of trichloroethanol and trichloroacetic acid in the urine and the trichloroethylene content of the atmosphere, as determined by field work].
Topics: Atmosphere; Ethanol; Ethylene Chlorohydrin; Humans; Trichloroacetic Acid; Trichloroethylene | 1958 |
[Determination of the electrical irritability of the motor cerebral cortex and its use in pharmacology and toxicology. III. Comparison of the narcotic effect of trichlorethylene and trichlorethanol in guinea pigs].
Topics: Animals; Cerebral Cortex; Ethanol; Ethylene Chlorohydrin; Guinea Pigs; Narcotics; Trichloroethylene | 1960 |
MODIFIED METHOD FOR DETERMINATION OF TRICHLOROETHANOL IN URINE.
Topics: Body Fluids; Chemistry Techniques, Analytical; Ethylene Chlorohydrin; Toxicology; Trichloroethylene; Urine | 1964 |
[Comparative effects of trichloroethylene and trichloroethanol on cortical function and spinal reflexes].
Topics: Cerebral Cortex; Ethanol; Ethylene Chlorohydrin; Reflex; Spinal Cord; Trichloroethylene | 1962 |
Exposure to trichloroethylene and its metabolites causes impairment of sperm fertilizing ability in mice.
Topics: Acrosome Reaction; Anesthetics, Intravenous; Animals; Body Weight; Chloral Hydrate; Epididymis; Ethylene Chlorohydrin; Female; Fertilization; Fertilization in Vitro; In Vitro Techniques; Inhalation Exposure; Male; Mice; Organ Size; Solvents; Sperm Count; Sperm Motility; Sperm-Ovum Interactions; Spermatozoa; Testis; Trichloroethylene | 2004 |
Dose-dependent liver regeneration in chloroform, trichloroethylene and allyl alcohol ternary mixture hepatotoxicity in rats.
Topics: Administration, Oral; Animals; Chloroform; D-Alanine Transaminase; Drug Interactions; Ethylene Chlorohydrin; Injections, Intraperitoneal; Liver; Liver Regeneration; Male; Propanols; Rats; Rats, Sprague-Dawley; Trichloroacetic Acid; Trichloroethylene | 2005 |
Application of cryopreserved human hepatocytes in trichloroethylene risk assessment: relative disposition of chloral hydrate to trichloroacetate and trichloroethanol.
Topics: Adult; Aged; Alcohol Dehydrogenase; Aldehyde Dehydrogenase; Animals; Chloral Hydrate; Cryopreservation; Ethylene Chlorohydrin; Female; Genotype; Hepatocytes; Humans; In Vitro Techniques; Kinetics; Male; Middle Aged; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Risk Assessment; Solvents; Trichloroacetic Acid; Trichloroethylene | 2006 |
Bayesian population analysis of a harmonized physiologically based pharmacokinetic model of trichloroethylene and its metabolites.
Topics: Animals; Bayes Theorem; Chloral Hydrate; Dichloroacetic Acid; Dose-Response Relationship, Drug; Ethylene Chlorohydrin; Humans; Kinetics; Markov Chains; Mice; Models, Biological; Monte Carlo Method; Rats; Sulfhydryl Compounds; Trichloroacetic Acid; Trichloroethylene | 2006 |
Acute, nonfatal intoxication with trichloroethylene.
Topics: Acetylglucosaminidase; Acute Disease; Biomarkers; Ethylene Chlorohydrin; Glutamate-Ammonia Ligase; Humans; Inhalation Exposure; Kidney Diseases; Male; Middle Aged; Occupational Diseases; Proteinuria; Solvents; Trichloroacetic Acid; Trichloroethylene | 2007 |
Mechanistics of trichloroethylene mineralization by the white-rot fungus Trametes versicolor.
Topics: Carbon Dioxide; Chlorides; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Ethylene Chlorohydrin; Laccase; Polyporales; Triazoles; Trichloroethylene; Water Pollutants, Chemical | 2008 |
Trichloroethanol up-regulates matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 in HaCaT cells.
Topics: Air Pollutants, Occupational; Cell Line; Cell Survival; Ethylene Chlorohydrin; Humans; Hypersensitivity; Keratinocytes; Matrix Metalloproteinase 9; RNA, Messenger; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2; Trichloroacetic Acid; Trichloroethylene; Up-Regulation | 2011 |
Trichloroethylene-induced formic aciduria: effect of dose, sex and strain of rat.
Topics: Animals; Cytochrome P-450 CYP2E1; Dose-Response Relationship, Drug; Enzyme Induction; Ethylene Chlorohydrin; Female; Formates; Kidney; Male; Rats; Rats, Inbred F344; Rats, Wistar; Sex Factors; Solvents; Species Specificity; Time Factors; Trichloroacetic Acid; Trichloroethylene | 2013 |
Micronucleus induction by oxidative metabolites of trichloroethylene in cultured human peripheral blood lymphocytes: a comparative genotoxicity study.
Topics: Cells, Cultured; DNA Damage; Ethylene Chlorohydrin; Hazardous Substances; Humans; Lymphocytes; Micronuclei, Chromosome-Defective; Micronucleus Tests; Mutagens; Oxidation-Reduction; Trichloroethylene | 2013 |
Sex differences in metabolism of trichloroethylene and trichloroethanol in guinea pigs.
Topics: Allergens; Animals; Dermatitis, Allergic Contact; Ethylene Chlorohydrin; Female; Gas Chromatography-Mass Spectrometry; Guinea Pigs; Injections, Intramuscular; Male; Trichloroacetic Acid; Trichloroethylene | 2013 |
Trichloroethylene and trichloroethanol-induced formic aciduria and renal injury in male F-344 rats following 12 weeks exposure.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Acetylglucosaminidase; Animals; Cell Adhesion Molecules; Ethylene Chlorohydrin; Formates; Kidney; Liver; Male; Methylmalonic Acid; Organ Size; Rats; Rats, Inbred F344; Solvents; Toxicity Tests, Subchronic; Trichloroethylene | 2014 |
Comparative analysis of the relationship between trichloroethylene metabolism and tissue-specific toxicity among inbred mouse strains: liver effects.
Topics: Administration, Oral; Animals; Carcinogens; Cell Proliferation; Cysteine; Cytochrome P-450 Enzyme System; Dichloroacetic Acid; Dose-Response Relationship, Drug; Ethylene Chlorohydrin; Gene Expression; Glutathione; Hepatocytes; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Oxidation-Reduction; Oxidative Stress; Real-Time Polymerase Chain Reaction; Solvents; Trichloroacetic Acid; Trichloroethylene | 2015 |
Comparative analysis of the relationship between trichloroethylene metabolism and tissue-specific toxicity among inbred mouse strains: kidney effects.
Topics: Animals; Carcinogens; Cell Proliferation; Cysteine; Cytochrome P-450 Enzyme System; Dichloroacetic Acid; Ethylene Chlorohydrin; Glutathione; Hepatitis A Virus Cellular Receptor 1; Kidney; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Oxidation-Reduction; PPAR alpha; Trichloroacetic Acid; Trichloroethylene | 2015 |
In vivo effects of naproxen, salicylic acid, and valproic acid on the pharmacokinetics of trichloroethylene and metabolites in rats.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Ethylene Chlorohydrin; Male; Models, Theoretical; Naproxen; Rats; Rats, Sprague-Dawley; Risk Assessment; Salicylic Acid; Solvents; Trichloroacetic Acid; Trichloroethylene; Valproic Acid | 2015 |
Trichloroethylene and trichloroethanol induce skin sensitization with focal hepatic necrosis in guinea pigs.
Topics: Animals; Chemical and Drug Induced Liver Injury; Ethylene Chlorohydrin; Female; Guinea Pigs; Hypersensitivity; Necrosis; Occupational Exposure; Skin Diseases; Trichloroacetic Acid; Trichloroethylene | 2020 |
Effect of trichloroethanol on TLR2 and TLR4/NF-κB-mediated antigen processing and presentation in HLA-B* 13:01-transfected antigen-presenting cells.
Topics: Antigen Presentation; Antigen-Presenting Cells; HLA-B Antigens; Humans; NF-kappa B; Toll-Like Receptor 2; Toll-Like Receptor 4; Trichloroethylene | 2023 |