Page last updated: 2024-08-18

2,2,2-trichloroethanol and formic acid

2,2,2-trichloroethanol has been researched along with formic acid in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19901 (20.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Crippen, GM; Ghose, AK1
Dow, J; Foster, J; Green, T1
Lock, EA; McMillan, JM; Oatis, JE; Reed, CJ; Schnellmann, RG1
Evans, AR; Lock, EA; Yaqoob, N1
Evans, A; Foster, JR; Lock, EA; Yaqoob, N1

Other Studies

5 other study(ies) available for 2,2,2-trichloroethanol and formic acid

ArticleYear
Use of physicochemical parameters in distance geometry and related three-dimensional quantitative structure-activity relationships: a demonstration using Escherichia coli dihydrofolate reductase inhibitors.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Binding Sites; Escherichia coli; Folic Acid Antagonists; Models, Molecular; Protein Conformation; Structure-Activity Relationship

1985
Increased formic acid excretion and the development of kidney toxicity in rats following chronic dosing with trichloroethanol, a major metabolite of trichloroethylene.
    Toxicology, 2003, Sep-30, Volume: 191, Issue:2-3

    Topics: Acetylglucosamine; Animals; Blood Chemical Analysis; Bromodeoxyuridine; Ethylene Chlorohydrin; Formates; Histocytochemistry; Kidney Diseases; Kidney Neoplasms; Male; Methylmalonic Acid; Random Allocation; Rats; Rats, Inbred F344; Sex Factors; Trichloroethylene

2003
Lack of formic acid production in rat hepatocytes and human renal proximal tubule cells exposed to chloral hydrate or trichloroacetic acid.
    Toxicology, 2007, Feb-12, Volume: 230, Issue:2-3

    Topics: Adolescent; Adult; Animals; Chemical and Drug Induced Liver Injury; Chloral Hydrate; Chromatography, Gas; Ethylene Chlorohydrin; Formates; Hepatocytes; Humans; Kidney Diseases; Kidney Tubules, Proximal; Liver Diseases; Magnetic Resonance Spectroscopy; Male; Rats; Trichloroacetic Acid

2007
Trichloroethylene-induced formic aciduria: effect of dose, sex and strain of rat.
    Toxicology, 2013, Feb-08, Volume: 304

    Topics: Animals; Cytochrome P-450 CYP2E1; Dose-Response Relationship, Drug; Enzyme Induction; Ethylene Chlorohydrin; Female; Formates; Kidney; Male; Rats; Rats, Inbred F344; Rats, Wistar; Sex Factors; Solvents; Species Specificity; Time Factors; Trichloroacetic Acid; Trichloroethylene

2013
Trichloroethylene and trichloroethanol-induced formic aciduria and renal injury in male F-344 rats following 12 weeks exposure.
    Toxicology, 2014, Sep-02, Volume: 323

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Acetylglucosaminidase; Animals; Cell Adhesion Molecules; Ethylene Chlorohydrin; Formates; Kidney; Liver; Male; Methylmalonic Acid; Organ Size; Rats; Rats, Inbred F344; Solvents; Toxicity Tests, Subchronic; Trichloroethylene

2014