2,2,2-trichloroethanol has been researched along with ethylene chlorohydrin in 166 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 48 (28.92) | 18.7374 |
| 1990's | 47 (28.31) | 18.2507 |
| 2000's | 47 (28.31) | 29.6817 |
| 2010's | 23 (13.86) | 24.3611 |
| 2020's | 1 (0.60) | 2.80 |
| Authors | Studies |
|---|---|
| Charlier, M; Privat, JP | 1 |
| Miller, KW; Wilson, MW | 1 |
| Flanagan, RJ; Lee, TD; Rutherford, DM | 1 |
| Mantel, M; Nothmann, R | 1 |
| Gorczak, J; Krasts, M; Vesterberg, O | 2 |
| Berry, DJ | 1 |
| Casas-Finet, JR; Karpel, RL; Wilson, SH | 1 |
| Gorecki, DK; Hindmarsh, KW; Mayers, DJ; Sankaran, K | 1 |
| Brodersen, R; Onks, DL; Robertson, AF | 1 |
| Caplan, YH; Goldberger, BA; Heller, PF | 1 |
| Ansari, GA; Asimakis, GK; Bhat, HK | 1 |
| Anyebuno, MA; Rosenfeld, CR | 1 |
| Haroutunian, AV; Mardanian, SS; Sarkissova, YG | 1 |
| Gupta, RN | 1 |
| Gorecki, DK; Hall, CA; Hindmarsh, KW; Mayers, DJ; Sankaran, K | 1 |
| Ageishi, Y; Kobayashi, M; Nakayama, H; Takahashi, M; Takano, T | 1 |
| Buben, JA; O'Flaherty, EJ | 1 |
| Jastak, JT; Pallasch, T | 1 |
| Hobara, T; Iwamoto, S; Kawamoto, T; Kobayashi, H; Sakai, T | 1 |
| Fraser, JM; Kaminsky, LS | 1 |
| Hobara, T; Iwamoto, S; Kawamoto, T; Kobayashi, H; Ogino, K; Sakai, T | 1 |
| Hobara, T; Imamura, A; Iwamoto, S; Kawamoto, T; Kobayashi, H; Koshiro, A; Sakai, T | 1 |
| Lowry, LK | 1 |
| Aitio, A; Pekari, K | 1 |
| Montoya, GA; Riker, WK; Russell, NJ | 1 |
| Carlson, GP; White, JF | 1 |
| De Saint Blanquat, G; Elfassy, B; Sharkawi, M | 1 |
| Laptook, AR; Rosenfeld, CR | 1 |
| Higashihara, E; Hobara, T; Kawamoto, T; Kobayashi, H; Sakai, T | 1 |
| Fujita, H; Ikeda, M; Koizumi, A; Kumai, M; Sadamoto, T; Yamamoto, M | 1 |
| Bradley, RJ; Hermes, M; Peper, K; Sterz, R | 1 |
| DiGregorio, GJ; Fruncillo, RJ | 1 |
| Brooks, JB; Edman, DC | 1 |
| Eftink, MR; Ghiron, CA | 1 |
| Chmara, D; Faure, J; Gu, ZW; Jalbert, P; Marka, C; Sele, B; Vincent, F; Vincent, M | 1 |
| Fentiman, AF; Leighty, EG | 1 |
| Carlson, GP | 1 |
| Crovato, E; Re, MR | 1 |
| Amgarten, M; Schatzmann, HJ; Wüthrich, A | 1 |
| Fu, PP; Kadlubar, FF; Ni, YC | 1 |
| Barnes, NM; Belelli, D; Bentley, KR; Chen, CY; Downie, DL; Hope, AG; Lambert, JJ; Peters, JA; Steward, LJ | 1 |
| Horiguchi, S; Ikeda, M; Kawai, T; Mizunuma, K | 1 |
| Burback, BL; Perry, JJ; Vanderberg, LA | 1 |
| Peoples, RW; Weight, FF | 2 |
| Ichinose, N; Ikeda, S; Itoh, H | 1 |
| Highsmith, S; Papp, SJ | 1 |
| Harrison, NL; Jones, MV; Levitin, M; Lovinger, DM; Zimmerman, SA | 1 |
| Lovinger, DM; Zhou, Q | 1 |
| Brodeur, J; Laparé, S; Tardif, R | 1 |
| Bédouin, J; Gaillard, Y; Garnier, R; Pépin, G | 1 |
| Jamey, C; Kintz, P; Mangin, P | 1 |
| Benane, SG; Blackman, CF; House, DE | 1 |
| Birner, G; Dekant, W; Rutkowska, A | 1 |
| Casciano, D; Fu, PP; Heinze, TM; Kadlubar, FF; Lloyd, RV; Ni, YC; Shelton, S; Wong, TY | 1 |
| Baker, GB; Dringenberg, HC; Urichuk, LJ; Vanderwolf, CH | 1 |
| Fukabori, S; Hara, K; Nakaaki, K; Yamamura, Y; Yoshida, K; Yoshida, M; Yuasa, H | 1 |
| Amiss, TJ; Smoak, IW | 1 |
| Bull, RJ; Merdink, JL; Springer, DL; Stenner, RD; Stevens, DK | 1 |
| Davydova, N; Henderson, GN; James, MO; Stacpoole, PW; Yan, Z | 1 |
| Foster, JR; Green, T; Mainwaring, GW | 1 |
| Czajkowski, C; Hadingham, KL; Harrison, NL; Krasowski, MD; O'Shea, SM; Rick, CE; Whiting, PJ | 1 |
| Abbas, R; Fisher, JW | 1 |
| Simon, TW | 1 |
| Gotoh, M; Hobara, T; Kobayashi, H; Okuda, M | 1 |
| Finn, SE; Harrison, NL; Krasowski, MD; Ye, Q | 1 |
| Lovinger, DM; Verdoorn, TA; Zhou, Q | 1 |
| Elfarra, AA; Krause, RJ; Lash, LH; Last, AR; Parker, JC | 1 |
| Dawson, BV; Goldberg, SJ; Johnson, PD | 1 |
| Barnes, NM; Bentley, KR | 1 |
| Bull, RJ; Gonzalez-Leon, A; Merdink, JL; Schultz, IR | 1 |
| Abbas, R; Fisher, JW; Mahle, D | 1 |
| Faci, A; Plaa, GL; Sharkawi, M | 1 |
| Burton, GA; Fisher, JW; Greenberg, MS | 1 |
| Allgaier, C; Illes, P; Kronfeld, A; Scheibler, P | 1 |
| Sperhake, J; Sperhake, K; Tsokos, M | 1 |
| Henderson, GN; James, MO; Stacpoole, PW; Yan, Z | 1 |
| Lovinger, DM; Sung, KW; Zhou, Q | 1 |
| Allgaier, C; Fischer, W; Illes, P | 1 |
| Fürst, S; Illes, P; Köles, L; Wirkner, K; Wnendt, S | 1 |
| Blaszkewicz, M; Bolt, HM; Brüning, T; De Smet, K; Rogiers, V; Vercruysse, A | 1 |
| Bloemen, LJ; Commandeur, JN; Kezic, S; Monster, AC; Vermeulen, NP; Veulemans, H; Wilmer, JW | 1 |
| Courtiade, B; Gaulier, JM; Haglund, P; Lacassie, E; Lachâtre, G; Marquet, P; Merle, G | 1 |
| Doty, SL; Gordon, MP; Howald, WN; Shang, TQ; Wilson, AM | 1 |
| Blainey, PC; Reid, PJ | 1 |
| Johansson, JS; Solt, K | 1 |
| Brüning, T; Fels, LM; Fricke, HH; Mensing, T; Voss, B; Welge, P; Wilhelm, M | 1 |
| Gruss, M; Hempelmann, G; Scholz, A | 1 |
| Chaïb, N; Dehaye, JP; Fernandez, M; Keskiner, N; Marino, A; Métioui, M; Pochet, S | 1 |
| Garcia, C; Lucchinetti, E; Pasch, T; Schaub, MC; Spahn, DR; Zaugg, M | 1 |
| Bucci, TJ; Chou, MW; Fu, PP; Kadlubar, FF; Samokyszyn, VM; Von Tungeln, LS; Yi, P | 1 |
| Alpert, B; Royer, C; Twist, C | 1 |
| Forkert, PG; Lash, LH; Nadeau, V; Simmonds, A; Tardif, R | 1 |
| Deng, YY; Huang, JX; Li, LY; Tang, XJ | 1 |
| Báthory, G; Gergely, A; Gyimesi-Forrás, K; Mészáros, G; Szász, G | 1 |
| Allgaier, C; Eberts, C; Fischer, W; Franke, H; Gillen, C; Illes, P; Köles, L; Reinhardt, R; Weber, M; Wirkner, K | 1 |
| Johansson, JS; Reddy, KS; Solt, K | 1 |
| Dow, J; Foster, J; Green, T | 1 |
| DI CARLO, V | 1 |
| MARSHALL, EK; OWENS, AH | 3 |
| BROUN, GO; LASAGNA, L; MARSHALL, EK; OWENS, AH; ZUBROD, CG | 1 |
| STYBLOVA, V; TEISINGER, J; VLACHOVA, D | 1 |
| DYBING, F; DYBING, O | 1 |
| VLACHOVA, D | 2 |
| MEDEK, V | 1 |
| COBEY, F; FINNEGAN, JK; HAAG, HB; HENNIGAR, GR; LARSON, PS; SMITH, RB | 1 |
| BARTONICEK, V | 1 |
| MIKISKA, A; MIKISKOVA, H | 1 |
| BROWN, DA | 1 |
| CEJKOVA, B; DUCHON, J; RICHTER, AF | 1 |
| KULESZA, K | 1 |
| MIKISKOVA, H | 1 |
| Edwards, RA; Ladner, CL; Turner, RJ; Yang, J | 1 |
| Harinath, S; Sikdar, SK | 1 |
| Breese, GR; Criswell, HE; Griffith, BL; Ming, Z; Mueller, RA; Pleasant, N | 1 |
| Anupriwan, A; Forkert, PG; Leader, A; Tanphaichitr, N; Vincent, R; Wade, MG; Weerachatyanukul, W; Xu, H | 1 |
| Igisu, H; Narimatsu, H | 1 |
| Dills, RL; Johns, DO; Morgan, MS | 1 |
| Anand, SS; Mehendale, HM; Mumtaz, MM | 1 |
| Harrold, G; Leharne, SA; Lerner, DN | 1 |
| Dillon, GH; Hayrapetyan, V; Jenschke, M; Machu, TK | 1 |
| Gadhiya, JJ; Hayrapetyan, V; Hu, XQ; Lovinger, DM; Machu, TK; Rhubottom, HE | 1 |
| Edwards, RA; Ladner, CL; Schriemer, DC; Turner, RJ | 1 |
| Ikeda, M; Inoue, O; Ukai, H | 1 |
| Ingram, LJ; Taylor, SD | 1 |
| Appel, SB; Brodie, MS; Koyama, S; McDaid, J; McElvain, MA; Wise, L | 1 |
| Bronley-DeLancey, A; Hoel, DG; Jollow, DJ; McMillan, DC; McMillan, JM; Mohr, LC | 1 |
| Chiu, WA; Clewell, HJ; Hack, CE; Jay Zhao, Q | 1 |
| Lock, EA; McMillan, JM; Oatis, JE; Reed, CJ; Schnellmann, RG | 1 |
| Bartolucci, GB; Carrieri, M; Magosso, D; Piccoli, P; Trevisan, A; Zanetti, E | 1 |
| Edwards, RA; Ladner, CL; Turner, RJ | 1 |
| Adinarayana Reddy, C; Caminal, G; Gabarrell, X; Marco-Urrea, E; Parella, T; Vicent, T | 1 |
| Hu, XQ; Peoples, RW | 1 |
| Bull, RJ; Hu, M; Merdink, JL; Parker, JC; Robison, LM; Stevens, DK | 1 |
| Jones, GR; Singer, PP | 1 |
| Barton, JW; Davison, BH; Flanary, SA; Vodraska, CD | 1 |
| Arndt, T; Gierten, B; Grüner, J; Güssregen, B; Werle, A | 1 |
| Dogan-Duyar, S; Duval, EL; Neels, H; Van Hee, P; Willemse, JL | 1 |
| Hu, XQ; Lamb, KA; Lipsky, RH; Peoples, RW; Ren, H; Salous, AK | 1 |
| Andresen, J; Bryan, RM; Jansen, K; Parelkar, NK; Silswal, N; Vaughn, J | 1 |
| Chattopadhyay, A; Chaudhuri, A; Haldar, S; Kelkar, DA | 1 |
| Bonvallot, N; Cordier, S; Dananché, B; Garlantézec, R; Labat, L; Monfort, C; Multigner, L; Pulkkinen, J; Rouget, F | 1 |
| Bin, P; Dai, Y; Dong, H; Duan, H; Liu, Q; Niu, Y; Yang, H; Zang, D; Zheng, Y | 1 |
| Evans, AR; Lock, EA; Yaqoob, N | 1 |
| Chandra, A; Chauhan, LK; Goel, SK; Varshney, M | 1 |
| Hibino, Y; Huang, H; Huang, Y; Ito, Y; Jia, X; Kamijima, M; Li, H; Liu, L; Naito, H; Nakajima, T; Song, X; Wang, D; Wang, H; Zhao, N | 1 |
| Evans, A; Foster, JR; Lock, EA; Yaqoob, N | 1 |
| Ball, LM; Bodnar, WM; Bradford, BU; Collins, LB; Gold, A; Kosyk, O; Rusyn, I; Shymonyak, S; Uehara, T; Yoo, HS | 2 |
| Liu, L; Liu, X; Lou, H; Meng, Z; Sun, S | 1 |
| Cai, Y; Ding, H; Gao, J; Xue, J; Yang, C; Zhang, Y | 1 |
| Alexander, KM; McAuley, KB; Nasr, AT; Olding, T; Schreiner, LJ | 1 |
| Alexander, K; McAuley, KB; Nasr, AT; Schreiner, LJ | 1 |
| Charest-Tardif, G; Haddad, S; Rouhou, MC | 1 |
| Bheri, S; Ethier, CR; Mulvihill, J; Raykin, J; Snider, E | 1 |
| Alam, MT; Furkan, M; Naeem, A; Rizvi, A | 1 |
| Baumann, U; Chojnacki, K; Denzel, MS; Hermanns, T; Hofmann, K; Niefind, K; Öcal, S; Pichlo, C; Ruegenberg, S; Schacherl, M; Toelzer, C; Uthoff, M | 1 |
| Edwards, RA; Ladner-Keay, CL; Turner, RJ | 1 |
| Del Pilar Delgado, M; Haas, R; Jaramillo, C; Jiménez-Soto, LF; Joppich, M; Rojas-Rengifo, DF; Ulloa-Guerrero, CP | 1 |
| Hashimoto, S; Inoue, M; Ito, Y; Kamijima, M; Nakahira, Y; Nakajima, T; Sato, H | 1 |
| Biggar, KK; Chopra, A; Willmore, WG | 1 |
| Cai, T; Huang, H; Huang, Y; Ito, Y; Kamijima, M; Li, H; Liu, L; Lu, F; Naito, H; Nakajima, T; Song, X; Wang, H; Zhao, N | 1 |
2 review(s) available for 2,2,2-trichloroethanol and ethylene chlorohydrin
| Article | Year |
|---|---|
Fluorescence quenching studies with proteins.
Topics: Acetamides; Acrylamide; Acrylamides; Alcohol Oxidoreductases; Azurin; Chemical Phenomena; Chemistry, Physical; Ethylene Chlorohydrin; Fluorescence; Hydrogen Peroxide; Indoles; Kinetics; Liver; Luminescent Measurements; Mathematics; Plant Proteins; Proteins; Pyridinium Compounds; Sodium Iodide; Succinimides; Tryptophan; Tyrosine | 1981 |
[Trichloroacetic acid and trichloroethanol in urine].
Topics: Biomarkers; Chromatography, Gas; Environmental Exposure; Environmental Monitoring; Ethylene Chlorohydrin; Reference Values; Solvents; Specimen Handling; Tetrachloroethylene; Trichloroacetic Acid; Trichloroethanes; Trichloroethylene | 2004 |
2 trial(s) available for 2,2,2-trichloroethanol and ethylene chlorohydrin
| Article | Year |
|---|---|
Kinetics and metabolism of chloral hydrate in children: identification of dichloroacetate as a metabolite.
Topics: Acidosis, Lactic; Adolescent; Biotransformation; Child; Child, Preschool; Chloral Hydrate; Dichloroacetic Acid; Ethylene Chlorohydrin; Gas Chromatography-Mass Spectrometry; Glucuronates; Humans; Hypnotics and Sedatives; Infant; Kinetics | 1997 |
A human physiologically based pharmacokinetic model for trichloroethylene and its metabolites, trichloroacetic acid and free trichloroethanol.
Topics: Administration, Inhalation; Adult; Ethylene Chlorohydrin; Female; Humans; Male; Models, Biological; Sex Factors; Solvents; Time Factors; Tissue Distribution; Trichloroacetic Acid; Trichloroethylene | 1998 |
162 other study(ies) available for 2,2,2-trichloroethanol and ethylene chlorohydrin
| Article | Year |
|---|---|
Photochemical modifications of the tryptophan residues of wheat-germ agglutinin in the presence of trichloroethanol.
Topics: Agglutinins; Chitin; Chlorohydrins; Ethylene Chlorohydrin; Hemagglutination; Protein Binding; Protein Conformation; Spectrometry, Fluorescence; Triticum; Tryptophan; Ultraviolet Rays | 1978 |
The pressure reversal of a variety of anesthetic agents in mice.
Topics: Alfaxalone Alfadolone Mixture; Anesthesia, General; Anesthetics; Animals; Atmospheric Pressure; Chloralose; Chlorohydrins; Dose-Response Relationship, Drug; Ethylene Chlorohydrin; Ketamine; Male; Mice; Phenobarbital; Urethane | 1978 |
Analysis of chlormethiazole, ethchlorvynol and trichloroethanol in biological fluids by gas-liquid chromatography as an aid to the diagnosis of acute poisoning.
Topics: Chlormethiazole; Chlorohydrins; Chromatography, Gas; Chromatography, Liquid; Ethchlorvynol; Ethylene Chlorohydrin; Humans; Poisoning | 1978 |
Rapid determination of trichloroethanol and trichloroacetic acid in urine.
Topics: Chlorohydrins; Ethylene Chlorohydrin; Methods; Spectrophotometry; Trichloroacetic Acid | 1977 |
Exposure to trichloroethylene II. Metabolites in blood and urine.
Topics: Chlorohydrins; Dose-Response Relationship, Drug; Environmental Exposure; Ethylene Chlorohydrin; Humans; Male; Occupational Medicine; Physical Exertion; Trichloroacetic Acid; Trichloroethylene | 1976 |
Determination of trichloroethanol at therapeutic and overdose levels in blood and urine by electron capture gas chromatography.
Topics: Chloral Hydrate; Chlorohydrins; Chromatography, Gas; Dose-Response Relationship, Drug; Ethanol; Ethylene Chlorohydrin; Humans; Poisoning | 1975 |
Methods for measuring trichloroethanol and trichloroacetic acid in blood and urine after exposure to trichloroethylene.
Topics: Biotransformation; Chlorohydrins; Environmental Exposure; Ethylene Chlorohydrin; Humans; Trichloroacetic Acid; Trichloroethylene | 1975 |
Selective photochemical modification by trichloroethanol of tryptophan residues in proteins with a high tyrosine-to-tryptophan ratio.
Topics: Animals; Cattle; DNA Helicases; DNA-Binding Proteins; Ethylene Chlorohydrin; Heterogeneous Nuclear Ribonucleoprotein A1; Heterogeneous-Nuclear Ribonucleoprotein Group A-B; Homeodomain Proteins; Minor Histocompatibility Antigens; Photochemistry; Proto-Oncogene Proteins c-bcl-2; Rats; Recombinant Proteins; Replication Protein C; Repressor Proteins; Ribonucleoproteins; Saccharomyces cerevisiae Proteins; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Thymus Hormones; Tryptophan; Tyrosine | 1992 |
Sedative/hypnotic effects of chloral hydrate in the neonate: trichloroethanol or parent drug?
Topics: Chloral Hydrate; Drug Administration Schedule; Ethylene Chlorohydrin; Half-Life; Humans; Individuality; Infant, Newborn | 1992 |
The effect of chloral hydrate and its metabolites, trichloroethanol and trichloroacetic acid, on bilirubin-albumin binding.
Topics: Bilirubin; Chloral Hydrate; Ethylene Chlorohydrin; Humans; Oxidation-Reduction; Protein Binding; Regression Analysis; Serum Albumin; Spectrophotometry, Ultraviolet; Trichloroacetic Acid | 1992 |
Chloral hydrate overdose: trichloroethanol detection by gas chromatography/mass spectrometry.
Topics: Adult; Chloral Hydrate; Drug Overdose; Ethylene Chlorohydrin; Female; Gas Chromatography-Mass Spectrometry; Gastrointestinal Contents; Half-Life; Humans; Suicide | 1992 |
Uncoupling of oxidative phosphorylation in rat liver mitochondria by chloroethanols.
Topics: Adenosine Triphosphate; Animals; Chromatography, High Pressure Liquid; Ethylene Chlorohydrin; Male; Mitochondria, Liver; Oxidative Phosphorylation; Oxygen Consumption; Rats; Rats, Inbred Strains; Structure-Activity Relationship | 1991 |
Chloral hydrate toxicity in a term infant.
Topics: Administration, Oral; Chloral Hydrate; Electrocardiography; Ethylene Chlorohydrin; Exchange Transfusion, Whole Blood; Humans; Infant, Newborn; Intensive Care Units, Neonatal; Male | 1991 |
The role of tryptophanyl residues in electron transfer from NADPH--adrenodoxin reductase to adrenodoxin.
Topics: Adrenal Cortex; Adrenodoxin; Bromosuccinimide; Cytochrome c Group; Electron Transport; Ethylene Chlorohydrin; Ferredoxin-NADP Reductase; Oxidation-Reduction; Spectrophotometry; Tryptophan | 1990 |
Determination of trichloroethanol, the active metabolite of chloral hydrate, in plasma by liquid chromatography.
Topics: Chloral Hydrate; Chlorohydrins; Chromatography, Liquid; Ethylene Chlorohydrin; Humans | 1990 |
Determination of chloral hydrate metabolism in adult and neonate biological fluids after single-dose administration.
Topics: Adult; Body Fluids; Chloral Hydrate; Chromatography, Gas; Ethylene Chlorohydrin; Humans; Infant; Male; Trichloroacetic Acid | 1990 |
Generalized eruption with severe liver dysfunction associated with occupational exposure to trichloroethylene.
Topics: Adult; Chemical and Drug Induced Liver Injury; Dermatitis, Occupational; Ethylene Chlorohydrin; Humans; Hypersensitivity, Delayed; Japan; Male; Occupational Diseases; Patch Tests; Staphylococcal Infections; Trichloroethylene | 1988 |
Delineation of the role of metabolism in the hepatotoxicity of trichloroethylene and perchloroethylene: a dose-effect study.
Topics: Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Ethylene Chlorohydrin; Glucose-6-Phosphatase; Liver Diseases; Male; Mice; Organ Size; Tetrachloroethylene; Trichloroacetic Acid; Trichloroethylene; Triglycerides | 1985 |
Death after chloral hydrate sedation: report of case.
Topics: Adult; Anesthesia, Dental; Chloral Hydrate; Ethylene Chlorohydrin; Female; Heart Arrest; Humans; Nerve Block; Preanesthetic Medication; Prognosis | 1988 |
The absorption of trichloroethylene and its metabolites from the urinary bladder of anesthetized dogs.
Topics: Animals; Bile; Chloral Hydrate; Dogs; Dose-Response Relationship, Drug; Ethylene Chlorohydrin; Female; Male; Trichloroacetic Acid; Trichloroethylene; Urinary Bladder | 1988 |
2,2,2-Trifluoroethanol intestinal and bone marrow toxicity: the role of its metabolism to 2,2,2-trifluoroacetaldehyde and trifluoroacetic acid.
Topics: Acetaldehyde; Animals; Bone Marrow; Chlorohydrins; Dose-Response Relationship, Drug; Ethylene Chlorohydrin; Fluoroacetates; Intestine, Small; Male; Pyrazoles; Rats; Rats, Inbred Strains; Trifluoroacetic Acid | 1988 |
Alteration of chloral hydrate metabolism in rats with carbon tetrachloride-induced liver damage.
Topics: Animals; Bile; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chloral Hydrate; Ethylene Chlorohydrin; Liver Diseases; Male; Metabolic Clearance Rate; Perfusion; Rats; Rats, Inbred Strains; Trichloroacetic Acid | 1987 |
The metabolism of trichloroethylene and its metabolites in the perfused liver.
Topics: Animals; Bile; Chloral Hydrate; Ethylene Chlorohydrin; Liver; Male; Perfusion; Rats; Rats, Inbred Strains; Trichloroacetic Acid; Trichloroethylene | 1987 |
The biological exposure index: its use in assessing chemical exposures in the workplace.
Topics: Acetates; Butanones; Environmental Exposure; Environmental Monitoring; Ethylene Chlorohydrin; Ethylene Glycols; Humans; Industry; Maximum Allowable Concentration; National Institute for Occupational Safety and Health, U.S.; Paint; Trichloroacetic Acid; Trichloroethylene; United States | 1987 |
Determination of 2,2,2-trichloroethanol in urine.
Topics: Air Pollutants, Occupational; Autoanalysis; Chlorohydrins; Chromatography, Gas; Ethylene Chlorohydrin; Humans; Indicators and Reagents; Safety; Trichloroethylene | 1985 |
A comparison of ethanol, acetaldehyde and trichloroethanol effects on ganglionic transmission.
Topics: Acetaldehyde; Animals; Anura; Chlorohydrins; Ethanol; Ethylene Chlorohydrin; Ganglia; In Vitro Techniques; Rana catesbeiana; Synaptic Transmission | 1980 |
Cardiac arrhythmogenic action of benzo(a)pyrene in the rabbit.
Topics: Animals; Arrhythmias, Cardiac; Benzo(a)pyrene; Benzopyrenes; Epinephrine; Ethylene Chlorohydrin; Halothane; Male; Methylcholanthrene; Phenobarbital; Rabbits; Time Factors; Trichloroacetic Acid; Trichloroethylene | 1983 |
Inhibition of alcohol dehydrogenase by chloral hydrate and trichloroethanol: possible role in the chloral hydrate-ethanol interaction.
Topics: Alcohol Dehydrogenase; Alcohol Oxidoreductases; Animals; Binding, Competitive; Chloral Hydrate; Chlorohydrins; Ethanol; Ethylene Chlorohydrin; Kinetics; Liver; Male; Mice; Posture; Reflex | 1983 |
Chloral hydrate toxicity in a preterm infant.
Topics: Chloral Hydrate; Ethylene Chlorohydrin; Half-Life; Humans; Hyaline Membrane Disease; Infant, Newborn; Infant, Premature; Kinetics; Male; Respiration, Artificial; Time Factors | 1984 |
[Experimental studies of trichloroethylene toxicity. II. Changes in trichloroethylene metabolites in blood serum and in urine during and after exposure to trichloroethylene].
Topics: Animals; Chlorohydrins; Dogs; Environmental Exposure; Ethylene Chlorohydrin; Trichloroacetic Acid; Trichloroethylene | 1983 |
Inhibition of delta-aminolevulinic acid dehydratase by trichloroethylene.
Topics: 5-Aminolevulinate Synthetase; Animals; Bone Marrow; Erythrocytes; Ethylene Chlorohydrin; In Vitro Techniques; Liver; Male; Phenobarbital; Porphobilinogen Synthase; Rats; Rats, Inbred Strains; Trichloroacetic Acid; Trichloroethanes; Trichloroethylene | 1984 |
Effects of halogenated derivatives of ethanol on the nicotine acetylcholine receptor.
Topics: Acetylcholine; Animals; Chlorohydrins; Dose-Response Relationship, Drug; Ethanol; Ethylene Chlorohydrin; Motor Endplate; Neuromuscular Junction; Rana esculenta; Receptors, Cholinergic; Trifluoroethanol | 1981 |
The effect of thermal injury on drug metabolism in the rat.
Topics: Animals; Anti-Inflammatory Agents; Burns; Dose-Response Relationship, Drug; Ethylene Chlorohydrin; Female; Immunosuppressive Agents; Male; Microsomes, Liver; Nitroanisole O-Demethylase; Pharmaceutical Preparations; Phenobarbital; Rats; Rats, Inbred Strains; Sex Factors; Sleep; Splenomegaly; Time Factors | 1983 |
Gas-liquid chromatography-frequency pulse-modulated electron-capture detection in the diagnosis of infectious diseases.
Topics: Alcohols; Bacteria; Bacterial Infections; Body Fluids; Chromatography, Gas; Computers; Ethylene Chlorohydrin; Fatty Acids; Fluorocarbons; Humans; Hydroxy Acids; Pleural Effusion; Species Specificity | 1983 |
[Induction of sister chromatide exchange by trichloroethylene and its metabolites (author's transl)].
Topics: Chloral Hydrate; Chlorohydrins; Crossing Over, Genetic; Ethylene Chlorohydrin; Humans; In Vitro Techniques; Mutagenicity Tests; Mutagens; Sister Chromatid Exchange; Trichloroethylene | 1981 |
In vitro conjugation of the trichloroethylene metabolite trichloroethanol to a fatty acid.
Topics: Animals; Chlorohydrins; Coenzyme A; Ethylene Chlorohydrin; Fatty Acids; In Vitro Techniques; Microsomes; Palmitic Acids; Rats; Trichloroethylene | 1981 |
Effect of alterations in drug metabolism on epinephrine-induced cardiac arrhythmias in rabbits exposed to methylchloroform.
Topics: Animals; Antimetabolites; Arrhythmias, Cardiac; Biphenyl Compounds; Cytochrome P-450 Enzyme System; Diethylamines; Epinephrine; Ethylene Chlorohydrin; Hydrocarbons, Chlorinated; Male; Phenobarbital; Proadifen; Rabbits; Trichloroacetic Acid; Trichloroethanes | 1981 |
[Percutaneous absorption of trieline with warning levels of the biological indices].
Topics: Air Pollutants, Occupational; Environmental Exposure; Ethylene Chlorohydrin; Humans; Risk; Skin Absorption; Trichloroacetic Acid; Trichloroethylene | 1981 |
'Lactate type' response of ruminal fermentation to chloral hydrate, chloroform and trichloroethanol.
Topics: Animals; Cattle; Chloral Hydrate; Chloroform; Chlorohydrins; Ethylene Chlorohydrin; Fatty Acids; Female; Fermentation; Lactates; Lactic Acid; Oxidation-Reduction; Rumen | 1981 |
Formation of malondialdehyde-modified 2'-deoxyguanosinyl adduct from metabolism of chloral hydrate by mouse liver microsomes.
Topics: Animals; Cattle; Chloral Hydrate; Chromatography, High Pressure Liquid; Deoxyguanosine; DNA; DNA Adducts; Ethylene Chlorohydrin; Isotope Labeling; Lipid Peroxidation; Male; Malondialdehyde; Mice; Microsomes, Liver; Phosphorus Radioisotopes; Trichloroacetic Acid | 1995 |
The interaction of trichloroethanol with murine recombinant 5-HT3 receptors.
Topics: Animals; Binding, Competitive; Cell Line; Chloral Hydrate; Dose-Response Relationship, Drug; Ethanol; Ethylene Chlorohydrin; Ion Channels; Mice; Oocytes; Quipazine; Radioligand Assay; Receptors, Serotonin; Recombinant Proteins; Xenopus laevis | 1995 |
Urinary methylchloroform rather than urinary metabolites as an indicator of occupational exposure to methylchloroform.
Topics: Chemical Industry; Chromatography, Gas; Colorimetry; Environmental Monitoring; Ethylene Chlorohydrin; Humans; Male; Occupational Exposure; Regression Analysis; Sensitivity and Specificity; Trichloroacetic Acid; Trichloroethanes; Urinalysis | 1995 |
Biodegradation of trichloroethylene by Mycobacterium vaccae.
Topics: Biodegradation, Environmental; Ethylene Chlorohydrin; Mycobacterium; Toluene; Trichloroethylene | 1995 |
Trichloroethanol potentiation of gamma-aminobutyric acid-activated chloride current in mouse hippocampal neurones.
Topics: Animals; Cells, Cultured; Chloride Channels; Drug Synergism; Ethanol; Ethylene Chlorohydrin; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Hippocampus; Mice; Muscimol; Neurons; Patch-Clamp Techniques; Pentobarbital; Receptors, GABA-A; Up-Regulation | 1994 |
Determination of 2,2,2-trichloroethanol in plasma and urine by ion-exclusion chromatography.
Topics: Adult; Animals; Chromatography, Gel; Ethylene Chlorohydrin; Glucuronates; Humans; Male; Rats; Rats, Sprague-Dawley | 1994 |
The ATP-induced myosin subfragment-1 fluorescence intensity increase is due to one tryptophan.
Topics: Adenosine Triphosphate; Animals; Ca(2+) Mg(2+)-ATPase; Ethylene Chlorohydrin; Fluorescence; Muscles; Myosin Subfragments; Myosins; Tryptophan | 1993 |
Trichloroethanol potentiates synaptic transmission mediated by gamma-aminobutyric acidA receptors in hippocampal neurons.
Topics: Action Potentials; Anesthesia, General; Anesthetics; Animals; Cells, Cultured; Chloride Channels; Drug Synergism; Ethylene Chlorohydrin; Female; gamma-Aminobutyric Acid; Hippocampus; Membrane Proteins; Pregnancy; Rats; Receptors, GABA-A; Synapses; Synaptic Transmission | 1993 |
Trichloroethanol potentiation of 5-hydroxytryptamine3 receptor-mediated ion current in nodose ganglion neurons from the adult rat.
Topics: Animals; Ethylene Chlorohydrin; Membrane Potentials; Neurons; Nodose Ganglion; Rats; Receptors, Serotonin | 1993 |
Effect of various exposure scenarios on the biological monitoring of organic solvents in alveolar air. II. 1,1,1-Trichloroethane and trichloroethylene.
Topics: Adult; Air Pollutants, Occupational; Environmental Monitoring; Ethylene Chlorohydrin; Female; Humans; Male; Middle Aged; Occupational Exposure; Physical Exertion; Pulmonary Alveoli; Solvents; Time Factors; Trichloroacetic Acid; Trichloroethanes; Trichloroethylene | 1995 |
Coin-operated dry cleaning machines may be responsible for acute tetrachloroethylene poisoning: report of 26 cases including one death.
Topics: Adult; Child, Preschool; Ethylene Chlorohydrin; Fatal Outcome; Female; Humans; Laundering; Male; Middle Aged; Poison Control Centers; Poisoning; Retrospective Studies; Tetrachloroethylene; Tissue Distribution; Trichloroacetic Acid | 1996 |
Trichloroethanol is not a metabolite of alpha chloralose.
Topics: Adult; Chloralose; Ethylene Chlorohydrin; Humans; Hypnotics and Sedatives; Male; Middle Aged | 1996 |
Effect of perchloroethylene and its metabolites on intercellular communication in clone 9 rat liver cells.
Topics: Analysis of Variance; Animals; Chloral Hydrate; Clone Cells; Dichloroacetic Acid; Ethylene Chlorohydrin; Gap Junctions; Liver; Male; Rats; Rats, Sprague-Dawley; Tetrachloroethylene; Trichloroacetic Acid; Water Pollutants | 1996 |
N-acetyl-S-(1,2,2-trichlorovinyl)-L-cysteine and 2,2,2-trichloroethanol: two novel metabolites of tetrachloroethene in humans after occupational exposure.
Topics: Acetylcysteine; Adult; Biotransformation; Chromatography, Gas; Ethylene Chlorohydrin; Female; Humans; Male; Mass Spectrometry; Middle Aged; Occupational Exposure | 1996 |
Mouse liver microsomal metabolism of chloral hydrate, trichloroacetic acid, and trichloroethanol leading to induction of lipid peroxidation via a free radical mechanism.
Topics: Allopurinol; Animals; Catalysis; Cell Line; Chloral Hydrate; Ethylene Chlorohydrin; Free Radicals; Gas Chromatography-Mass Spectrometry; Horseradish Peroxidase; Humans; Lipid Peroxidation; Male; Mice; Microsomes, Liver; NAD; NADP; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Trichloroacetic Acid; Xanthine Oxidase | 1996 |
Anti-serotonergic effects of urethane and chloral hydrate may not be mediated by a blockade of 5-HT2 receptors. Short communication.
Topics: Anesthetics, Intravenous; Animals; Binding, Competitive; Chloral Hydrate; Ethylene Chlorohydrin; Ketanserin; Male; Membrane Proteins; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin Antagonists; Synaptic Transmission; Tritium; Urethane | 1996 |
Concentrations of trichloroethylene and its metabolites in blood and urine after acute poisoning by ingestion.
Topics: Accidents, Home; Administration, Oral; Ethylene Chlorohydrin; Humans; Male; Middle Aged; Trichloroacetic Acid; Trichloroethylene | 1996 |
Determination of chlorobutanol in mouse serum, urine and embryos by capillary gas chromatography with electron capture detection.
Topics: Animals; Chlorobutanol; Chromatography, Gas; Embryo, Mammalian; Ethylene Chlorohydrin; Female; Mice; Mice, Inbred Strains; Pregnancy; Sensitivity and Specificity | 1995 |
Enterohepatic recirculation of trichloroethanol glucuronide as a significant source of trichloroacetic acid. Metabolites of trichloroethylene.
Topics: Animals; Bile; Chromatography, Gas; Enterohepatic Circulation; Ethylene Chlorohydrin; Glucuronates; Male; Rats; Rats, Inbred F344; Trichloroacetic Acid; Trichloroethylene | 1997 |
Trichloroethylene-induced mouse lung tumors: studies of the mode of action and comparisons between species.
Topics: Administration, Inhalation; Animals; Blotting, Western; Cell Division; Chloral Hydrate; Cytochrome P-450 CYP2E1; Ethylene Chlorohydrin; Female; Glucuronates; Humans; Immunoenzyme Techniques; In Vitro Techniques; Lung; Lung Neoplasms; Male; Mice; Microsomes; Microsomes, Liver; Rats; Rats, Wistar; Solvents; Species Specificity; Trichloroethylene | 1997 |
Alpha subunit isoform influences GABA(A) receptor modulation by propofol.
Topics: Anesthetics, Intravenous; Animals; Cell Line; Dose-Response Relationship, Drug; Ethylene Chlorohydrin; Methohexital; Mice; Muscimol; Patch-Clamp Techniques; Propofol; Receptors, GABA-A; Stereoisomerism | 1997 |
A physiologically based pharmacokinetic model for trichloroethylene and its metabolites, chloral hydrate, trichloroacetate, dichloroacetate, trichloroethanol, and trichloroethanol glucuronide in B6C3F1 mice.
Topics: Administration, Oral; Animals; Chloral Hydrate; Dichloroacetic Acid; Ethylene Chlorohydrin; Feces; Glucuronates; Liver; Male; Mice; Mice, Inbred Strains; Models, Biological; Solvents; Tissue Distribution; Trichloroacetic Acid; Trichloroethylene | 1997 |
Combining physiologically based pharmacokinetic modeling with Monte Carlo simulation to derive an acute inhalation guidance value for trichloroethylene.
Topics: Administration, Inhalation; Body Fluid Compartments; Computer Simulation; Dose-Response Relationship, Drug; Ethylene Chlorohydrin; Female; Humans; Male; Models, Biological; Monte Carlo Method; Occupational Exposure; Sensitivity and Specificity; Solvents; Trichloroethylene | 1997 |
Pollution due to trichloroacetic acid in clams (Tapes japonica) in an estuary adjacent to industrial areas.
Topics: Animals; Bivalvia; Environmental Monitoring; Ethylene Chlorohydrin; Industry; Japan; Seawater; Shellfish; Trichloroacetic Acid; Volatilization; Water Pollutants, Chemical | 1998 |
Trichloroethanol modulation of recombinant GABAA, glycine and GABA rho 1 receptors.
Topics: Amino Acid Sequence; Cells, Cultured; Dose-Response Relationship, Drug; Ethylene Chlorohydrin; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Receptors, GABA; Receptors, GABA-A; Receptors, Glycine; Structure-Activity Relationship | 1998 |
Alcohols potentiate the function of 5-HT3 receptor-channels on NCB-20 neuroblastoma cells by favouring and stabilizing the open channel state.
Topics: Alcohols; Algorithms; Brain Neoplasms; Butanols; Central Nervous System Depressants; Computer Simulation; Electrophysiology; Ethanol; Ethylene Chlorohydrin; Humans; Ion Channels; Kinetics; Membrane Potentials; Models, Neurological; Neuroblastoma; Patch-Clamp Techniques; Receptors, Serotonin; Serotonin Receptor Agonists; Tumor Cells, Cultured | 1998 |
Species- and sex-related differences in metabolism of trichloroethylene to yield chloral and trichloroethanol in mouse, rat, and human liver microsomes.
Topics: Acetates; Animals; Chloral Hydrate; Dichloroacetic Acid; Ethylene Chlorohydrin; Female; Glyoxylates; Humans; Kinetics; Male; Mice; Microsomes, Liver; NADP; Oxalates; Oxalic Acid; Rats; Rats, Inbred F344; Sex Factors; Solvents; Species Specificity; Trichloroethylene | 1998 |
Cardiac teratogenicity of trichloroethylene metabolites.
Topics: Abnormalities, Drug-Induced; Acetaldehyde; Acetates; Animals; Chloral Hydrate; Cystine; Dichloroethylenes; Embryonic and Fetal Development; Environmental Pollutants; Ethylene Chlorohydrin; Female; Heart; Heart Defects, Congenital; Humans; Maternal Exposure; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Teratogens; Trichloroacetic Acid; Trichloroethylene; Water Pollutants, Chemical; Water Supply | 1998 |
Inhibition of excitatory amino acid-activated currents by trichloroethanol and trifluoroethanol in mouse hippocampal neurones.
Topics: Animals; Cells, Cultured; Ethylene Chlorohydrin; Hippocampus; Mice; N-Methylaspartate; Neurons; Trifluoroethanol | 1998 |
5-hydroxytryptamine3 (5-HT3) receptor-mediated depolarisation of the rat isolated vagus nerve: modulation by trichloroethanol and related alcohols.
Topics: Animals; Chlorohydrins; Drug Interactions; Ethanol; Ethylene Chlorohydrin; Female; In Vitro Techniques; Indoles; Pentanols; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin Antagonists; Serotonin Receptor Agonists; Sulfonamides; Vagus Nerve | 1998 |
The extent of dichloroacetate formation from trichloroethylene, chloral hydrate, trichloroacetate, and trichloroethanol in B6C3F1 mice.
Topics: Animals; Biological Availability; Chloral Hydrate; Dichloroacetic Acid; Ethylene Chlorohydrin; Half-Life; Male; Metabolic Clearance Rate; Mice; Models, Biological; Trichloroacetic Acid; Trichloroethylene | 1998 |
Chloral hydrate enhances ethanol-induced inhibition of methanol oxidation in mice.
Topics: Alcohol Dehydrogenase; Animals; Chloral Hydrate; Drug Combinations; Drug Synergism; Enzyme Inhibitors; Ethanol; Ethylene Chlorohydrin; Half-Life; Liver; Metabolic Clearance Rate; Methanol; Mice; Mice, Inbred Strains; Oxidation-Reduction | 1998 |
Physiologically based pharmacokinetic modeling of inhaled trichloroethylene and its oxidative metabolites in B6C3F1 mice.
Topics: Adipose Tissue; Administration, Inhalation; Animals; Chloral Hydrate; Dichloroacetic Acid; Ethylene Chlorohydrin; Kidney; Liver; Lung; Male; Metabolic Clearance Rate; Mice; Mice, Inbred Strains; Models, Biological; Oxidation-Reduction; Sensitivity and Specificity; Solvents; Tissue Distribution; Trichloroacetic Acid; Trichloroethylene | 1999 |
Trichloroethanol impairs NMDA receptor function in rat mesencephalic and cortical neurones.
Topics: Animals; Calcium; Cells, Cultured; Cerebral Cortex; Ethylene Chlorohydrin; Excitatory Amino Acid Agonists; Fetus; Fura-2; Mesencephalon; N-Methylaspartate; Neurons; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 1999 |
Perimortem fixation of the gastric and duodenal mucosa: a diagnostic indication for oral poisoning.
Topics: Adult; Chloral Hydrate; Duodenum; Ethylene Chlorohydrin; Gastric Mucosa; Humans; Intestinal Mucosa; Male; Mercury Poisoning; Poisoning; Postmortem Changes; Sensitivity and Specificity; Tissue Fixation | 1999 |
Determination of chloral hydrate metabolites in human plasma by gas chromatography-mass spectrometry.
Topics: Acetals; Acetates; Acidosis, Lactic; Administration, Oral; Child; Chloral Hydrate; Dichloroacetic Acid; Ethylene Chlorohydrin; Evaluation Studies as Topic; Gas Chromatography-Mass Spectrometry; Glucuronates; Glucuronides; Humans; Hydroxamic Acids; Reproducibility of Results; Sensitivity and Specificity; Trichloroacetic Acid | 1999 |
Ethanol and trichloroethanol alter gating of 5-HT3 receptor-channels in NCB-20 neuroblastoma cells.
Topics: Dopamine; Ethanol; Ethylene Chlorohydrin; Ion Channel Gating; Patch-Clamp Techniques; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin Receptor Agonists; Tumor Cells, Cultured | 2000 |
Inhibition by chloral hydrate and trichloroethanol of AMPA-induced Ca(2+) influx in rat cultured cortical neurones.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cells, Cultured; Cerebral Cortex; Chloral Hydrate; Dose-Response Relationship, Drug; Ethylene Chlorohydrin; Fluorometry; Rats; Rats, Wistar | 2000 |
Trichloroethanol inhibits ATP-induced membrane currents in cultured HEK 293-hP2X3 cells.
Topics: Adenosine Triphosphate; Cell Line; Central Nervous System Depressants; Ethanol; Ethylene Chlorohydrin; Humans; Ion Channels; Membrane Potentials; Receptors, Purinergic P2; Receptors, Purinergic P2X3 | 2000 |
Biotransformation of trichloroethylene in collagen gel sandwich cultures of rat hepatocytes.
Topics: Animals; Animals, Outbred Strains; Biotransformation; Cells, Cultured; Chromatography, Gas; Collagen; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2B1; Cytochrome P-450 CYP2E1; Ethylene Chlorohydrin; Extracellular Matrix; Hepatocytes; Male; Models, Biological; Rats; Rats, Sprague-Dawley; Trichloroacetic Acid; Trichloroethylene | 2000 |
Study on the cytochrome P-450- and glutathione-dependent biotransformation of trichloroethylene in humans.
Topics: Adult; Air Pollutants, Occupational; Biomarkers; Biotransformation; Cytochrome P-450 Enzyme System; Ethylene Chlorohydrin; Glutathione; Humans; Male; Middle Aged; Occupational Exposure; Trichloroacetic Acid; Trichloroethylene | 2001 |
Fatal intoxications with chloral hydrate.
Topics: Adult; Alcoholism; Chloral Hydrate; Drug Overdose; Ethylene Chlorohydrin; Fatal Outcome; Female; Gas Chromatography-Mass Spectrometry; Humans; Hypnotics and Sedatives; Male; Substance-Related Disorders | 2001 |
Trichloroethylene oxidative metabolism in plants: the trichloroethanol pathway.
Topics: Ethylene Chlorohydrin; Mass Spectrometry; Nicotiana; Oxidation-Reduction; Trichloroethylene | 2001 |
FTIR studies of intermolecular hydrogen bonding in halogenated ethanols.
Topics: Dimerization; Ethanol; Ethylene Chlorohydrin; Hydrogen Bonding; Spectroscopy, Fourier Transform Infrared; Trifluoroethanol | 2001 |
Binding of the active metabolite of chloral hydrate, 2,2,2-trichloroethanol, to serum albumin demonstrated using tryptophan fluorescence quenching.
Topics: Animals; Cattle; Chloral Hydrate; Circular Dichroism; Ethylene Chlorohydrin; Humans; Hypnotics and Sedatives; Protein Binding; Protein Conformation; Serum Albumin; Spectrometry, Fluorescence; Tryptophan | 2002 |
Renal toxicity after chronic inhalation exposure of rats to trichloroethylene.
Topics: Acetylglucosaminidase; Albuminuria; Animals; Comet Assay; DNA Fragmentation; Ethylene Chlorohydrin; Histocytochemistry; Inhalation Exposure; Kidney Diseases; Male; Rats; Rats, Long-Evans; Trichloroacetic Acid; Trichloroethylene | 2002 |
Trichloroethanol alters action potentials in a subgroup of primary sensory neurones.
Topics: Action Potentials; Anesthetics, Intravenous; Animals; Chloral Hydrate; Ethylene Chlorohydrin; Female; Ganglia, Spinal; Lectins; Male; Nerve Fibers; Neurons, Afferent; Nociceptors; Organ Culture Techniques; Pain; Peptides; Potassium Channels, Calcium-Activated; Rats; Rats, Wistar | 2002 |
Multiple effects of trichloroethanol on calcium handling in rat submandibular acinar cells.
Topics: Anesthetics; Animals; Calcium; Calcium Channels; Calcium-Transporting ATPases; Enzyme Activation; Enzyme Inhibitors; Ethylene Chlorohydrin; In Vitro Techniques; Inositol Phosphates; Male; Microsomes; Purinergic P2 Receptor Agonists; Rats; Rats, Wistar; Receptors, Purinergic P2X2; Spectrum Analysis; Submandibular Gland; Thapsigargin; Time Factors; Type C Phospholipases | 2002 |
Differential effects of anesthetics on mitochondrial K(ATP) channel activity and cardiomyocyte protection.
Topics: Adenosine Triphosphate; Anesthetics; Animals; Cytoprotection; Diazoxide; Ethylene Chlorohydrin; Fentanyl; Heart; Ischemic Preconditioning, Myocardial; Male; Mitochondria, Heart; Potassium Channels; Protective Agents; Protein Kinase C; Rats; Rats, Sprague-Dawley; Urethane | 2002 |
Tumorigenicity of chloral hydrate, trichloroacetic acid, trichloroethanol, malondialdehyde, 4-hydroxy-2-nonenal, crotonaldehyde, and acrolein in the B6C3F(1) neonatal mouse.
Topics: Acrolein; Aldehydes; Animals; Animals, Newborn; Carcinogenicity Tests; Carcinogens; Chloral Hydrate; Chromatography, High Pressure Liquid; Crosses, Genetic; DNA; DNA Adducts; Electrochemistry; Ethylene Chlorohydrin; Female; Lipid Peroxidation; Liver; Liver Neoplasms, Experimental; Male; Malondialdehyde; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Microsomes, Liver; Phosphorus Radioisotopes; Trichloroacetic Acid | 2002 |
Effect of solvent diffusion on the apomyoglobin-water interface.
Topics: Ampholyte Mixtures; Animals; Apoproteins; Buffers; Diffusion; Ethylene Chlorohydrin; Horses; Hydrogen-Ion Concentration; Myoglobin; Osmotic Pressure; Polymers; Solvents; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Sucrose; Surface Properties; Tryptophan; Viscosity; Water | 2002 |
Metabolism and toxicity of trichloroethylene in epididymis and testis.
Topics: Administration, Inhalation; Animals; Blotting, Western; Chloral Hydrate; Cytochrome P-450 CYP2E1; Epididymis; Ethylene Chlorohydrin; Immunohistochemistry; Male; Mice; Microsomes; Occupational Exposure; Testis; Trichloroacetic Acid; Trichloroethylene | 2002 |
Guinea pig maximization test for trichloroethylene and its metabolites.
Topics: Allergens; Animals; Chloral Hydrate; Dermatitis, Allergic Contact; Dermatitis, Irritant; Ethylene Chlorohydrin; Guinea Pigs; Skin; Toxicity Tests; Trichloroacetic Acid; Trichloroethylene | 2002 |
Study on the sorption properties of alpha1-acid glycoprotein (AGP)-based stationary phase modified by organic solvents.
Topics: Absorption; Algorithms; Chromatography, Gas; Chromatography, High Pressure Liquid; Ethylene Chlorohydrin; Hydrogen-Ion Concentration; Indicators and Reagents; Orosomucoid; Solvents; Spectrometry, Fluorescence | 2003 |
Characterization of P2X3, P2Y1 and P2Y4 receptors in cultured HEK293-hP2X3 cells and their inhibition by ethanol and trichloroethanol.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Calcium; Cell Line; Dose-Response Relationship, Drug; Ethanol; Ethylene Chlorohydrin; Guanosine Triphosphate; Humans; Kidney; Patch-Clamp Techniques; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2X3; Receptors, Purinergic P2Y1; RNA, Messenger; Thionucleotides; Transfection; Uridine Triphosphate | 2003 |
Binding of the general anesthetics chloroform and 2,2,2-trichloroethanol to the hydrophobic core of a four-alpha-helix bundle proteins.
Topics: Amino Acid Sequence; Anesthetics; Binding Sites; Chloroform; Ethylene Chlorohydrin; Hydrophobic and Hydrophilic Interactions; Kinetics; Luminescence; Molecular Sequence Data; Protein Binding; Protein Structure, Secondary; Proteins; Tryptophan | 2003 |
Increased formic acid excretion and the development of kidney toxicity in rats following chronic dosing with trichloroethanol, a major metabolite of trichloroethylene.
Topics: Acetylglucosamine; Animals; Blood Chemical Analysis; Bromodeoxyuridine; Ethylene Chlorohydrin; Formates; Histocytochemistry; Kidney Diseases; Kidney Neoplasms; Male; Methylmalonic Acid; Random Allocation; Rats; Rats, Inbred F344; Sex Factors; Trichloroethylene | 2003 |
[Pharmacologic research on trichloroethanol-p-aminobenzoic acid].
Topics: Ethylene Chlorohydrin; Humans; para-Aminobenzoates; Research | 1953 |
Absorption, excretion and metabolic fate of chloral hydrate and trichloroethanol.
Topics: Biological Transport; Body Fluids; Chloral Hydrate; Ethanol; Ethylene Chlorohydrin; Humans | 1954 |
A comparative evaluation of the hypnotic potency of chloral hydrate and trichloroethanol. I. Studies at the Johns Hopkins University School of Medicine. II. Studies at the St. Louis University School of Medicine. III. Studies at Harvard Medical School.
Topics: Chloral Hydrate; Ethanol; Ethylene Chlorohydrin; Humans; Hypnotics and Sedatives; Medicine; Schools, Medical; Universities | 1955 |
Further studies on the metabolic fate of chloral hydrate and trichloroethanol.
Topics: Biochemical Phenomena; Blood; Chloral Hydrate; Ethanol; Ethylene Chlorohydrin; Humans; Trichloroacetic Acid; Trichloroethylene | 1955 |
A comparison of the metabolism of ethanol and trichloroethanol.
Topics: Ethanol; Ethylene Chlorohydrin; Humans | 1955 |
[Importance of determination of urinary trichloroethanol in workers exposed to trichloroethylene].
Topics: Ethylene Chlorohydrin; Humans; Trichloroethylene; Urinary Tract; Urine | 1955 |
Anticholinesterase and anticurare effects of chloral hydrate and trichloroethanol.
Topics: Chloral Hydrate; Cholinesterase Inhibitors; Curare; Ethanol; Ethylene Chlorohydrin; Humans | 1955 |
[Simple method of determination of trichloroethanol in urine].
Topics: Body Fluids; Ethanol; Ethylene Chlorohydrin; Humans | 1956 |
An easy method for the determination of trichlorethanol in the urine after exposure of trichlorethylene.
Topics: Ethanol; Ethylene Chlorohydrin; Humans; Trichloroethylene | 1957 |
[Relation between the content of trichloroethanol and trichloroacetic acid in the urine and the trichloroethylene content of the atmosphere, as determined by field work].
Topics: Atmosphere; Ethanol; Ethylene Chlorohydrin; Humans; Trichloroacetic Acid; Trichloroethylene | 1958 |
Toxicologic studies on 2,2-bis-(chlorophenyl)-2,2, 2-trichloroethanol (kelthane).
Topics: Dicofol; Ethylene Chlorohydrin; Humans; Insecticides | 1959 |
[The effect of various substances on urinary excretion of trichlorethanol and trichloroacetic acid in the rabbit].
Topics: Animals; Ethanol; Ethylene Chlorohydrin; Rabbits; Trichloroacetic Acid | 1960 |
[Determination of the electrical irritability of the motor cerebral cortex and its use in pharmacology and toxicology. III. Comparison of the narcotic effect of trichlorethylene and trichlorethanol in guinea pigs].
Topics: Animals; Cerebral Cortex; Ethanol; Ethylene Chlorohydrin; Guinea Pigs; Narcotics; Trichloroethylene | 1960 |
An eserine-like action of chloral hydrate.
Topics: Acetylcholine; Action Potentials; Animals; Carbachol; Cats; Chloral Hydrate; Cholinesterase Inhibitors; Ethylene Chlorohydrin; Ganglia; Injections, Intra-Arterial; Neostigmine; Nicotine; Physostigmine; Quaternary Ammonium Compounds; Rabbits; Rats | 1962 |
[Effect of trichloroethanol on amino acids and proteins].
Topics: Amino Acids; Antifibrinolytic Agents; Ethanol; Ethylene Chlorohydrin; Humans; Proteins | 1961 |
MODIFIED METHOD FOR DETERMINATION OF TRICHLOROETHANOL IN URINE.
Topics: Body Fluids; Chemistry Techniques, Analytical; Ethylene Chlorohydrin; Toxicology; Trichloroethylene; Urine | 1964 |
[Comparative effects of trichloroethylene and trichloroethanol on cortical function and spinal reflexes].
Topics: Cerebral Cortex; Ethanol; Ethylene Chlorohydrin; Reflex; Spinal Cord; Trichloroethylene | 1962 |
Visible fluorescent detection of proteins in polyacrylamide gels without staining.
Topics: Acrylic Resins; Electrophoresis, Gel, Two-Dimensional; Ethylene Chlorohydrin; Fluorescence; Proteins; Rosaniline Dyes; Staining and Labeling; Trichloroacetic Acid | 2004 |
Trichloroethanol enhances the activity of recombinant human TREK-1 and TRAAK channels.
Topics: Animals; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Ethylene Chlorohydrin; Humans; Membrane Potentials; Potassium Channels; Potassium Channels, Tandem Pore Domain; Rats; Recombinant Proteins | 2004 |
Macrokinetic analysis of blockade of NMDA-gated currents by substituted alcohols, alkanes and ethers.
Topics: Alcohols; Anesthetics, Inhalation; Animals; Cells, Cultured; Central Nervous System Depressants; Cerebral Cortex; Dose-Response Relationship, Drug; Ethanol; Ethylene Chlorohydrin; Halothane; Hexanols; Ion Channel Gating; Isoflurane; Membrane Potentials; Methyl Ethers; Models, Biological; Neurons; Patch-Clamp Techniques; Rats; Receptors, N-Methyl-D-Aspartate; Sevoflurane | 2004 |
Exposure to trichloroethylene and its metabolites causes impairment of sperm fertilizing ability in mice.
Topics: Acrosome Reaction; Anesthetics, Intravenous; Animals; Body Weight; Chloral Hydrate; Epididymis; Ethylene Chlorohydrin; Female; Fertilization; Fertilization in Vitro; In Vitro Techniques; Inhalation Exposure; Male; Mice; Organ Size; Solvents; Sperm Count; Sperm Motility; Sperm-Ovum Interactions; Spermatozoa; Testis; Trichloroethylene | 2004 |
Evaluation of dynamic headspace with gas chromatography/mass spectrometry for the determination of 1,1,1-trichloroethane, trichloroethanol, and trichloroacetic acid in biological samples.
Topics: Ethylene Chlorohydrin; Gas Chromatography-Mass Spectrometry; Humans; Trichloroacetic Acid; Trichloroethanes | 2005 |
Dose-dependent liver regeneration in chloroform, trichloroethylene and allyl alcohol ternary mixture hepatotoxicity in rats.
Topics: Administration, Oral; Animals; Chloroform; D-Alanine Transaminase; Drug Interactions; Ethylene Chlorohydrin; Injections, Intraperitoneal; Liver; Liver Regeneration; Male; Propanols; Rats; Rats, Sprague-Dawley; Trichloroacetic Acid; Trichloroethylene | 2005 |
The impact of additives found in industrial formulations of TCE on the wettability of sandstone.
Topics: Amines; Cetrimonium; Cetrimonium Compounds; Ethylene Chlorohydrin; Geologic Sediments; Hydrocarbons, Chlorinated; Solvents; Surface-Active Agents; Time Factors; Water; Wettability | 2005 |
Co-expression of the 5-HT(3B) subunit with the 5-HT(3A) receptor reduces alcohol sensitivity.
Topics: Animals; Cell Line; Central Nervous System Depressants; Dose-Response Relationship, Drug; Electric Stimulation; Ethanol; Ethylene Chlorohydrin; Gene Expression; Humans; Membrane Potentials; Mice; Patch-Clamp Techniques; Protein Subunits; Receptors, Serotonin, 5-HT3; Serotonin; Transfection | 2005 |
Mutations of L293 in transmembrane two of the mouse 5-hydroxytryptamine3A receptor alter gating and alcohol modulatory actions.
Topics: Allosteric Regulation; Animals; Cell Line; Central Nervous System Depressants; Dopamine; Dose-Response Relationship, Drug; Ethanol; Ethylene Chlorohydrin; Humans; Ion Channel Gating; Kinetics; Lysine; Membrane Potentials; Mice; Mutation; Oocytes; Patch-Clamp Techniques; Protein Structure, Tertiary; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin; Transfection; Xenopus laevis | 2006 |
Identification of trichloroethanol visualized proteins from two-dimensional polyacrylamide gels by mass spectrometry.
Topics: Amino Acid Sequence; Electrophoresis, Gel, Two-Dimensional; Escherichia coli Proteins; Ethylene Chlorohydrin; Mass Spectrometry; Molecular Sequence Data; Peptide Mapping; Proteins; Rosaniline Dyes; Sensitivity and Specificity | 2006 |
Green chemistry in urinalysis for trichloroethanol and trichloroacetic acid as markers of exposure to chlorinated hydrocarbon solvents.
Topics: Biomarkers; Ethylene Chlorohydrin; Female; Humans; Hydrocarbons, Chlorinated; Male; Occupational Exposure; Solvents; Trichloroacetic Acid | 2006 |
Introduction of 2,2,2-trichloroethyl-protected sulfates into monosaccharides with a sulfuryl imidazolium salt and application to the synthesis of sulfated carbohydrates.
Topics: Carbohydrates; Ethylene Chlorohydrin; Imidazoles; Models, Chemical; Sulfates; Sulfuric Acid Esters | 2006 |
The effects of long chain-length n-alcohols on the firing frequency of dopaminergic neurons of the ventral tegmental area.
Topics: Alcohols; Animals; Dose-Response Relationship, Drug; Ethylene Chlorohydrin; Hydrophobic and Hydrophilic Interactions; Male; Membrane Potentials; Rats; Rats, Inbred F344; Structure-Activity Relationship; Ventral Tegmental Area | 2006 |
Application of cryopreserved human hepatocytes in trichloroethylene risk assessment: relative disposition of chloral hydrate to trichloroacetate and trichloroethanol.
Topics: Adult; Aged; Alcohol Dehydrogenase; Aldehyde Dehydrogenase; Animals; Chloral Hydrate; Cryopreservation; Ethylene Chlorohydrin; Female; Genotype; Hepatocytes; Humans; In Vitro Techniques; Kinetics; Male; Middle Aged; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Risk Assessment; Solvents; Trichloroacetic Acid; Trichloroethylene | 2006 |
Bayesian population analysis of a harmonized physiologically based pharmacokinetic model of trichloroethylene and its metabolites.
Topics: Animals; Bayes Theorem; Chloral Hydrate; Dichloroacetic Acid; Dose-Response Relationship, Drug; Ethylene Chlorohydrin; Humans; Kinetics; Markov Chains; Mice; Models, Biological; Monte Carlo Method; Rats; Sulfhydryl Compounds; Trichloroacetic Acid; Trichloroethylene | 2006 |
Lack of formic acid production in rat hepatocytes and human renal proximal tubule cells exposed to chloral hydrate or trichloroacetic acid.
Topics: Adolescent; Adult; Animals; Chemical and Drug Induced Liver Injury; Chloral Hydrate; Chromatography, Gas; Ethylene Chlorohydrin; Formates; Hepatocytes; Humans; Kidney Diseases; Kidney Tubules, Proximal; Liver Diseases; Magnetic Resonance Spectroscopy; Male; Rats; Trichloroacetic Acid | 2007 |
Acute, nonfatal intoxication with trichloroethylene.
Topics: Acetylglucosaminidase; Acute Disease; Biomarkers; Ethylene Chlorohydrin; Glutamate-Ammonia Ligase; Humans; Inhalation Exposure; Kidney Diseases; Male; Middle Aged; Occupational Diseases; Proteinuria; Solvents; Trichloroacetic Acid; Trichloroethylene | 2007 |
Development of indole chemistry to label tryptophan residues in protein for determination of tryptophan surface accessibility.
Topics: Binding Sites; Carbonic Anhydrases; Chloroform; Ethylene Chlorohydrin; Indoles; Protein Structure, Tertiary; Proteins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tryptophan; Ultraviolet Rays | 2007 |
Mechanistics of trichloroethylene mineralization by the white-rot fungus Trametes versicolor.
Topics: Carbon Dioxide; Chlorides; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Ethylene Chlorohydrin; Laccase; Polyporales; Triazoles; Trichloroethylene; Water Pollutants, Chemical | 2008 |
Arginine 246 of the pretransmembrane domain 1 region alters 2,2,2-trichloroethanol action in the 5-hydroxytryptamine3A receptor.
Topics: Allosteric Regulation; Amino Acid Sequence; Animals; Arginine; Cell Line; Ethylene Chlorohydrin; Humans; Mice; Molecular Sequence Data; Point Mutation; Protein Structure, Tertiary; Receptors, Serotonin, 5-HT3; Serotonin 5-HT3 Receptor Agonists | 2008 |
Kinetics of chloral hydrate and its metabolites in male human volunteers.
Topics: Adult; Chloral Hydrate; Dichloroacetic Acid; Ethylene Chlorohydrin; Glucuronates; Humans; Liver; Male; Middle Aged; Time Factors; Trichloroacetic Acid | 2008 |
An unusual trichloroethanol fatality attributed to sniffing trichloroethylene.
Topics: Administration, Inhalation; Adult; Cause of Death; Chloral Hydrate; Chromatography, Gas; Ethylene Chlorohydrin; Fatal Outcome; Forensic Toxicology; Humans; Inhalation Exposure; Male; Substance Abuse Detection; Substance-Related Disorders | 2008 |
Solubility of toluene, benzene and TCE in high-microbial concentration systems.
Topics: Benzene; Biodegradation, Environmental; Biofilms; Biomass; Ethylene Chlorohydrin; Saccharomyces cerevisiae; Solubility; Toluene | 2008 |
False-positive ethyl glucuronide immunoassay screening associated with chloral hydrate medication as confirmed by LC-MS/MS and self-medication.
Topics: Adult; Biomarkers; Chloral Hydrate; Chromatography, Liquid; Cross Reactions; Ethylene Chlorohydrin; False Positive Reactions; Female; Forensic Toxicology; Glucuronates; Humans; Hypnotics and Sedatives; Immunoassay; Mass Spectrometry; Self Medication; Trichloroacetic Acid | 2009 |
Chloral hydrate intoxication in a 3-month-old child: avoidance of hemodialysis by an immediate determination of trichloroethanol.
Topics: Adult; Chloral Hydrate; Ethylene Chlorohydrin; Humans; Hypnotics and Sedatives; Infant; Mass Spectrometry; Renal Dialysis | 2010 |
Differential actions of ethanol and trichloroethanol at sites in the M3 and M4 domains of the NMDA receptor GluN2A (NR2A) subunit.
Topics: Cell Line; Ethanol; Ethylene Chlorohydrin; Humans; Mutation; Protein Structure, Tertiary; Protein Subunits; Receptors, N-Methyl-D-Aspartate | 2009 |
2,2,2-trichloroethanol activates a nonclassical potassium channel in cerebrovascular smooth muscle and dilates the middle cerebral artery.
Topics: Animals; Ethylene Chlorohydrin; Hypnotics and Sedatives; Immunohistochemistry; In Vitro Techniques; Isoflurane; Male; Membrane Potentials; Middle Cerebral Artery; Muscle, Smooth, Vascular; Patch-Clamp Techniques; Potassium Channels; Rats; Rats, Long-Evans; Vasodilator Agents | 2010 |
Exploring tryptophan dynamics in acid-induced molten globule state of bovine alpha-lactalbumin: a wavelength-selective fluorescence approach.
Topics: Acids; Acrylamide; Animals; Cattle; Ethylene Chlorohydrin; Fluorescence; Fluorescence Polarization; Hydrogen-Ion Concentration; Lactalbumin; Protein Denaturation; Protein Folding; Time Factors; Tryptophan | 2010 |
Urinary biomarkers of exposure to glycol ethers and chlorinated solvents during pregnancy: determinants of exposure and comparison with indirect methods of exposure assessment.
Topics: Adult; Biomarkers; Carboxylic Acids; Cohort Studies; Ethylene Chlorohydrin; Female; Humans; Maternal Exposure; Occupational Exposure; Pregnancy; Solvents; Surveys and Questionnaires; Trichloroacetic Acid | 2012 |
Trichloroethanol up-regulates matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 in HaCaT cells.
Topics: Air Pollutants, Occupational; Cell Line; Cell Survival; Ethylene Chlorohydrin; Humans; Hypersensitivity; Keratinocytes; Matrix Metalloproteinase 9; RNA, Messenger; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2; Trichloroacetic Acid; Trichloroethylene; Up-Regulation | 2011 |
Trichloroethylene-induced formic aciduria: effect of dose, sex and strain of rat.
Topics: Animals; Cytochrome P-450 CYP2E1; Dose-Response Relationship, Drug; Enzyme Induction; Ethylene Chlorohydrin; Female; Formates; Kidney; Male; Rats; Rats, Inbred F344; Rats, Wistar; Sex Factors; Solvents; Species Specificity; Time Factors; Trichloroacetic Acid; Trichloroethylene | 2013 |
Micronucleus induction by oxidative metabolites of trichloroethylene in cultured human peripheral blood lymphocytes: a comparative genotoxicity study.
Topics: Cells, Cultured; DNA Damage; Ethylene Chlorohydrin; Hazardous Substances; Humans; Lymphocytes; Micronuclei, Chromosome-Defective; Micronucleus Tests; Mutagens; Oxidation-Reduction; Trichloroethylene | 2013 |
Sex differences in metabolism of trichloroethylene and trichloroethanol in guinea pigs.
Topics: Allergens; Animals; Dermatitis, Allergic Contact; Ethylene Chlorohydrin; Female; Gas Chromatography-Mass Spectrometry; Guinea Pigs; Injections, Intramuscular; Male; Trichloroacetic Acid; Trichloroethylene | 2013 |
Trichloroethylene and trichloroethanol-induced formic aciduria and renal injury in male F-344 rats following 12 weeks exposure.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Acetylglucosaminidase; Animals; Cell Adhesion Molecules; Ethylene Chlorohydrin; Formates; Kidney; Liver; Male; Methylmalonic Acid; Organ Size; Rats; Rats, Inbred F344; Solvents; Toxicity Tests, Subchronic; Trichloroethylene | 2014 |
Comparative analysis of the relationship between trichloroethylene metabolism and tissue-specific toxicity among inbred mouse strains: liver effects.
Topics: Administration, Oral; Animals; Carcinogens; Cell Proliferation; Cysteine; Cytochrome P-450 Enzyme System; Dichloroacetic Acid; Dose-Response Relationship, Drug; Ethylene Chlorohydrin; Gene Expression; Glutathione; Hepatocytes; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Oxidation-Reduction; Oxidative Stress; Real-Time Polymerase Chain Reaction; Solvents; Trichloroacetic Acid; Trichloroethylene | 2015 |
Comparative analysis of the relationship between trichloroethylene metabolism and tissue-specific toxicity among inbred mouse strains: kidney effects.
Topics: Animals; Carcinogens; Cell Proliferation; Cysteine; Cytochrome P-450 Enzyme System; Dichloroacetic Acid; Ethylene Chlorohydrin; Glutathione; Hepatitis A Virus Cellular Receptor 1; Kidney; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Oxidation-Reduction; PPAR alpha; Trichloroacetic Acid; Trichloroethylene | 2015 |
Organocatalytic asymmetric C-H vinylation and arylation of N-acyl tetrahydroisoquinolines.
Topics: Boronic Acids; Catalysis; Ethylene Chlorohydrin; Molecular Structure; Stereoisomerism; Tetrahydroisoquinolines; Trifluoroethanol | 2015 |
2,2,2-Trichloroethanol lengthens the circadian period of Bmal1-driven circadian bioluminescence rhythms in U2OS cells.
Topics: Animals; ARNTL Transcription Factors; Cell Line; Chloral Hydrate; Circadian Rhythm; CLOCK Proteins; Ethylene Chlorohydrin; Humans; Hypnotics and Sedatives; Luminescent Measurements; Male; Mice; Nuclear Receptor Subfamily 1, Group D, Member 1; Period Circadian Proteins; Rats; Rats, Inbred F344 | 2015 |
Leuco-crystal-violet micelle gel dosimeters: II. Recipe optimization and testing.
Topics: Cetrimonium; Cetrimonium Compounds; Dose-Response Relationship, Radiation; Ethylene Chlorohydrin; Gels; Gentian Violet; Micelles; Phantoms, Imaging; Radiometry; Surface-Active Agents; Water | 2015 |
Leuco-crystal-violet micelle gel dosimeters: I. Influence of recipe components and potential sensitizers.
Topics: Cetrimonium; Cetrimonium Compounds; Dose-Response Relationship, Radiation; Ethylene Chlorohydrin; Gels; Gentian Violet; Hydrogen-Ion Concentration; Micelles; Octoxynol; Radiometry; Rosaniline Dyes; Surface-Active Agents; Trichloroacetic Acid | 2015 |
In vivo effects of naproxen, salicylic acid, and valproic acid on the pharmacokinetics of trichloroethylene and metabolites in rats.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Ethylene Chlorohydrin; Male; Models, Theoretical; Naproxen; Rats; Rats, Sprague-Dawley; Risk Assessment; Salicylic Acid; Solvents; Trichloroacetic Acid; Trichloroethylene; Valproic Acid | 2015 |
A modified gelatin zymography technique incorporating total protein normalization.
Topics: Electrophoresis, Polyacrylamide Gel; Ethylene Chlorohydrin; Fibrosarcoma; Gelatin; Gelatinases; Humans; Matrix Metalloproteinases; Tumor Cells, Cultured | 2017 |
Peroxidase improves the activity of catalase by preventing aggregation during TFE-induced denaturation.
Topics: Catalase; Circular Dichroism; Congo Red; Ethylene Chlorohydrin; Free Radical Scavengers; Peroxidase; Protein Aggregates; Protein Binding; Protein Conformation; Protein Denaturation; Protein Folding; Protein Multimerization; Spectrometry, Fluorescence | 2018 |
Improved protein-crystal identification by using 2,2,2-trichloroethanol as a fluorescence enhancer.
Topics: Ethylene Chlorohydrin; Microscopy, Fluorescence; Protein Structure, Secondary; Recombinant Proteins | 2018 |
Fluorescent Protein Visualization Immediately After Gel Electrophoresis Using an In-Gel Trichloroethanol Photoreaction with Tryptophan.
Topics: Electrophoresis, Polyacrylamide Gel; Ethylene Chlorohydrin; Luminescent Proteins; Photochemistry; Tryptophan | 2018 |
Tryptophan usage by Helicobacter pylori differs among strains.
Topics: DNA, Bacterial; Ethylene Chlorohydrin; Genome, Bacterial; Genotype; Helicobacter Infections; Helicobacter pylori; Humans; Multilocus Sequence Typing; Random Amplified Polymorphic DNA Technique; Reproducibility of Results; Sequence Analysis, DNA; Stomach Neoplasms; Tryptophan | 2019 |
Simple method to detect triclofos and its metabolites in plasma of children by combined use of liquid chromatography tandem-mass spectrometry and gas chromatography-mass spectrometry.
Topics: Child, Preschool; Chloral Hydrate; Chromatography, Liquid; Ethylene Chlorohydrin; Female; Gas Chromatography-Mass Spectrometry; Humans; Hydrolysis; Hypnotics and Sedatives; Infant; Japan; Limit of Detection; Male; Mass Spectrometry; Organophosphates; Reproducibility of Results; Tandem Mass Spectrometry; Trichloroacetic Acid | 2019 |
Protein quantification and visualization via ultraviolet-dependent labeling with 2,2,2-trichloroethanol.
Topics: Absorption, Radiation; Electrophoresis, Polyacrylamide Gel; Ethylene Chlorohydrin; Proteins; Proteomics; Tryptophan; Tyrosine; Ultraviolet Rays | 2019 |
Trichloroethylene and trichloroethanol induce skin sensitization with focal hepatic necrosis in guinea pigs.
Topics: Animals; Chemical and Drug Induced Liver Injury; Ethylene Chlorohydrin; Female; Guinea Pigs; Hypersensitivity; Necrosis; Occupational Exposure; Skin Diseases; Trichloroacetic Acid; Trichloroethylene | 2020 |