2,2,2-trichloroethanol has been researched along with chloral hydrate in 53 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (26.42) | 18.7374 |
| 1990's | 21 (39.62) | 18.2507 |
| 2000's | 14 (26.42) | 29.6817 |
| 2010's | 3 (5.66) | 24.3611 |
| 2020's | 1 (1.89) | 2.80 |
| Authors | Studies |
|---|---|
| Berry, DJ | 1 |
| Gorecki, DK; Hindmarsh, KW; Mayers, DJ; Sankaran, K | 1 |
| Brodersen, R; Onks, DL; Robertson, AF | 1 |
| Caplan, YH; Goldberger, BA; Heller, PF | 1 |
| Anyebuno, MA; Rosenfeld, CR | 1 |
| Gupta, RN | 1 |
| Gorecki, DK; Hall, CA; Hindmarsh, KW; Mayers, DJ; Sankaran, K | 1 |
| Jastak, JT; Pallasch, T | 1 |
| Hobara, T; Iwamoto, S; Kawamoto, T; Kobayashi, H; Sakai, T | 1 |
| Hobara, T; Iwamoto, S; Kawamoto, T; Kobayashi, H; Ogino, K; Sakai, T | 1 |
| Hobara, T; Imamura, A; Iwamoto, S; Kawamoto, T; Kobayashi, H; Koshiro, A; Sakai, T | 1 |
| De Saint Blanquat, G; Elfassy, B; Sharkawi, M | 1 |
| Laptook, AR; Rosenfeld, CR | 1 |
| Chmara, D; Faure, J; Gu, ZW; Jalbert, P; Marka, C; Sele, B; Vincent, F; Vincent, M | 1 |
| Amgarten, M; Schatzmann, HJ; Wüthrich, A | 1 |
| Fu, PP; Kadlubar, FF; Ni, YC | 1 |
| Barnes, NM; Belelli, D; Bentley, KR; Chen, CY; Downie, DL; Hope, AG; Lambert, JJ; Peters, JA; Steward, LJ | 1 |
| Benane, SG; Blackman, CF; House, DE | 1 |
| Casciano, D; Fu, PP; Heinze, TM; Kadlubar, FF; Lloyd, RV; Ni, YC; Shelton, S; Wong, TY | 1 |
| Baker, GB; Dringenberg, HC; Urichuk, LJ; Vanderwolf, CH | 1 |
| Davydova, N; Henderson, GN; James, MO; Stacpoole, PW; Yan, Z | 1 |
| Foster, JR; Green, T; Mainwaring, GW | 1 |
| Abbas, R; Fisher, JW | 1 |
| Elfarra, AA; Krause, RJ; Lash, LH; Last, AR; Parker, JC | 1 |
| Dawson, BV; Goldberg, SJ; Johnson, PD | 1 |
| Bull, RJ; Gonzalez-Leon, A; Merdink, JL; Schultz, IR | 1 |
| Faci, A; Plaa, GL; Sharkawi, M | 1 |
| Burton, GA; Fisher, JW; Greenberg, MS | 1 |
| Sperhake, J; Sperhake, K; Tsokos, M | 1 |
| Henderson, GN; James, MO; Stacpoole, PW; Yan, Z | 1 |
| Allgaier, C; Fischer, W; Illes, P | 1 |
| Courtiade, B; Gaulier, JM; Haglund, P; Lacassie, E; Lachâtre, G; Marquet, P; Merle, G | 1 |
| Johansson, JS; Solt, K | 1 |
| Gruss, M; Hempelmann, G; Scholz, A | 1 |
| Bucci, TJ; Chou, MW; Fu, PP; Kadlubar, FF; Samokyszyn, VM; Von Tungeln, LS; Yi, P | 1 |
| Forkert, PG; Lash, LH; Nadeau, V; Simmonds, A; Tardif, R | 1 |
| Deng, YY; Huang, JX; Li, LY; Tang, XJ | 1 |
| MARSHALL, EK; OWENS, AH | 2 |
| BROUN, GO; LASAGNA, L; MARSHALL, EK; OWENS, AH; ZUBROD, CG | 1 |
| DYBING, F; DYBING, O | 1 |
| BROWN, DA | 1 |
| Anupriwan, A; Forkert, PG; Leader, A; Tanphaichitr, N; Vincent, R; Wade, MG; Weerachatyanukul, W; Xu, H | 1 |
| Bronley-DeLancey, A; Hoel, DG; Jollow, DJ; McMillan, DC; McMillan, JM; Mohr, LC | 1 |
| Chiu, WA; Clewell, HJ; Hack, CE; Jay Zhao, Q | 1 |
| Lock, EA; McMillan, JM; Oatis, JE; Reed, CJ; Schnellmann, RG | 1 |
| Bull, RJ; Hu, M; Merdink, JL; Parker, JC; Robison, LM; Stevens, DK | 1 |
| Jones, GR; Singer, PP | 1 |
| Arndt, T; Gierten, B; Grüner, J; Güssregen, B; Werle, A | 1 |
| Dogan-Duyar, S; Duval, EL; Neels, H; Van Hee, P; Willemse, JL | 1 |
| Cai, Y; Ding, H; Gao, J; Xue, J; Yang, C; Zhang, Y | 1 |
| Hashimoto, S; Inoue, M; Ito, Y; Kamijima, M; Nakahira, Y; Nakajima, T; Sato, H | 1 |
| Jang, IS; Kim, G; Kim, H | 1 |
1 trial(s) available for 2,2,2-trichloroethanol and chloral hydrate
| Article | Year |
|---|---|
Kinetics and metabolism of chloral hydrate in children: identification of dichloroacetate as a metabolite.
Topics: Acidosis, Lactic; Adolescent; Biotransformation; Child; Child, Preschool; Chloral Hydrate; Dichloroacetic Acid; Ethylene Chlorohydrin; Gas Chromatography-Mass Spectrometry; Glucuronates; Humans; Hypnotics and Sedatives; Infant; Kinetics | 1997 |
52 other study(ies) available for 2,2,2-trichloroethanol and chloral hydrate
| Article | Year |
|---|---|
Determination of trichloroethanol at therapeutic and overdose levels in blood and urine by electron capture gas chromatography.
Topics: Chloral Hydrate; Chlorohydrins; Chromatography, Gas; Dose-Response Relationship, Drug; Ethanol; Ethylene Chlorohydrin; Humans; Poisoning | 1975 |
Sedative/hypnotic effects of chloral hydrate in the neonate: trichloroethanol or parent drug?
Topics: Chloral Hydrate; Drug Administration Schedule; Ethylene Chlorohydrin; Half-Life; Humans; Individuality; Infant, Newborn | 1992 |
The effect of chloral hydrate and its metabolites, trichloroethanol and trichloroacetic acid, on bilirubin-albumin binding.
Topics: Bilirubin; Chloral Hydrate; Ethylene Chlorohydrin; Humans; Oxidation-Reduction; Protein Binding; Regression Analysis; Serum Albumin; Spectrophotometry, Ultraviolet; Trichloroacetic Acid | 1992 |
Chloral hydrate overdose: trichloroethanol detection by gas chromatography/mass spectrometry.
Topics: Adult; Chloral Hydrate; Drug Overdose; Ethylene Chlorohydrin; Female; Gas Chromatography-Mass Spectrometry; Gastrointestinal Contents; Half-Life; Humans; Suicide | 1992 |
Chloral hydrate toxicity in a term infant.
Topics: Administration, Oral; Chloral Hydrate; Electrocardiography; Ethylene Chlorohydrin; Exchange Transfusion, Whole Blood; Humans; Infant, Newborn; Intensive Care Units, Neonatal; Male | 1991 |
Determination of trichloroethanol, the active metabolite of chloral hydrate, in plasma by liquid chromatography.
Topics: Chloral Hydrate; Chlorohydrins; Chromatography, Liquid; Ethylene Chlorohydrin; Humans | 1990 |
Determination of chloral hydrate metabolism in adult and neonate biological fluids after single-dose administration.
Topics: Adult; Body Fluids; Chloral Hydrate; Chromatography, Gas; Ethylene Chlorohydrin; Humans; Infant; Male; Trichloroacetic Acid | 1990 |
Death after chloral hydrate sedation: report of case.
Topics: Adult; Anesthesia, Dental; Chloral Hydrate; Ethylene Chlorohydrin; Female; Heart Arrest; Humans; Nerve Block; Preanesthetic Medication; Prognosis | 1988 |
The absorption of trichloroethylene and its metabolites from the urinary bladder of anesthetized dogs.
Topics: Animals; Bile; Chloral Hydrate; Dogs; Dose-Response Relationship, Drug; Ethylene Chlorohydrin; Female; Male; Trichloroacetic Acid; Trichloroethylene; Urinary Bladder | 1988 |
Alteration of chloral hydrate metabolism in rats with carbon tetrachloride-induced liver damage.
Topics: Animals; Bile; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chloral Hydrate; Ethylene Chlorohydrin; Liver Diseases; Male; Metabolic Clearance Rate; Perfusion; Rats; Rats, Inbred Strains; Trichloroacetic Acid | 1987 |
The metabolism of trichloroethylene and its metabolites in the perfused liver.
Topics: Animals; Bile; Chloral Hydrate; Ethylene Chlorohydrin; Liver; Male; Perfusion; Rats; Rats, Inbred Strains; Trichloroacetic Acid; Trichloroethylene | 1987 |
Inhibition of alcohol dehydrogenase by chloral hydrate and trichloroethanol: possible role in the chloral hydrate-ethanol interaction.
Topics: Alcohol Dehydrogenase; Alcohol Oxidoreductases; Animals; Binding, Competitive; Chloral Hydrate; Chlorohydrins; Ethanol; Ethylene Chlorohydrin; Kinetics; Liver; Male; Mice; Posture; Reflex | 1983 |
Chloral hydrate toxicity in a preterm infant.
Topics: Chloral Hydrate; Ethylene Chlorohydrin; Half-Life; Humans; Hyaline Membrane Disease; Infant, Newborn; Infant, Premature; Kinetics; Male; Respiration, Artificial; Time Factors | 1984 |
[Induction of sister chromatide exchange by trichloroethylene and its metabolites (author's transl)].
Topics: Chloral Hydrate; Chlorohydrins; Crossing Over, Genetic; Ethylene Chlorohydrin; Humans; In Vitro Techniques; Mutagenicity Tests; Mutagens; Sister Chromatid Exchange; Trichloroethylene | 1981 |
'Lactate type' response of ruminal fermentation to chloral hydrate, chloroform and trichloroethanol.
Topics: Animals; Cattle; Chloral Hydrate; Chloroform; Chlorohydrins; Ethylene Chlorohydrin; Fatty Acids; Female; Fermentation; Lactates; Lactic Acid; Oxidation-Reduction; Rumen | 1981 |
Formation of malondialdehyde-modified 2'-deoxyguanosinyl adduct from metabolism of chloral hydrate by mouse liver microsomes.
Topics: Animals; Cattle; Chloral Hydrate; Chromatography, High Pressure Liquid; Deoxyguanosine; DNA; DNA Adducts; Ethylene Chlorohydrin; Isotope Labeling; Lipid Peroxidation; Male; Malondialdehyde; Mice; Microsomes, Liver; Phosphorus Radioisotopes; Trichloroacetic Acid | 1995 |
The interaction of trichloroethanol with murine recombinant 5-HT3 receptors.
Topics: Animals; Binding, Competitive; Cell Line; Chloral Hydrate; Dose-Response Relationship, Drug; Ethanol; Ethylene Chlorohydrin; Ion Channels; Mice; Oocytes; Quipazine; Radioligand Assay; Receptors, Serotonin; Recombinant Proteins; Xenopus laevis | 1995 |
Effect of perchloroethylene and its metabolites on intercellular communication in clone 9 rat liver cells.
Topics: Analysis of Variance; Animals; Chloral Hydrate; Clone Cells; Dichloroacetic Acid; Ethylene Chlorohydrin; Gap Junctions; Liver; Male; Rats; Rats, Sprague-Dawley; Tetrachloroethylene; Trichloroacetic Acid; Water Pollutants | 1996 |
Mouse liver microsomal metabolism of chloral hydrate, trichloroacetic acid, and trichloroethanol leading to induction of lipid peroxidation via a free radical mechanism.
Topics: Allopurinol; Animals; Catalysis; Cell Line; Chloral Hydrate; Ethylene Chlorohydrin; Free Radicals; Gas Chromatography-Mass Spectrometry; Horseradish Peroxidase; Humans; Lipid Peroxidation; Male; Mice; Microsomes, Liver; NAD; NADP; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Trichloroacetic Acid; Xanthine Oxidase | 1996 |
Anti-serotonergic effects of urethane and chloral hydrate may not be mediated by a blockade of 5-HT2 receptors. Short communication.
Topics: Anesthetics, Intravenous; Animals; Binding, Competitive; Chloral Hydrate; Ethylene Chlorohydrin; Ketanserin; Male; Membrane Proteins; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin Antagonists; Synaptic Transmission; Tritium; Urethane | 1996 |
Trichloroethylene-induced mouse lung tumors: studies of the mode of action and comparisons between species.
Topics: Administration, Inhalation; Animals; Blotting, Western; Cell Division; Chloral Hydrate; Cytochrome P-450 CYP2E1; Ethylene Chlorohydrin; Female; Glucuronates; Humans; Immunoenzyme Techniques; In Vitro Techniques; Lung; Lung Neoplasms; Male; Mice; Microsomes; Microsomes, Liver; Rats; Rats, Wistar; Solvents; Species Specificity; Trichloroethylene | 1997 |
A physiologically based pharmacokinetic model for trichloroethylene and its metabolites, chloral hydrate, trichloroacetate, dichloroacetate, trichloroethanol, and trichloroethanol glucuronide in B6C3F1 mice.
Topics: Administration, Oral; Animals; Chloral Hydrate; Dichloroacetic Acid; Ethylene Chlorohydrin; Feces; Glucuronates; Liver; Male; Mice; Mice, Inbred Strains; Models, Biological; Solvents; Tissue Distribution; Trichloroacetic Acid; Trichloroethylene | 1997 |
Species- and sex-related differences in metabolism of trichloroethylene to yield chloral and trichloroethanol in mouse, rat, and human liver microsomes.
Topics: Acetates; Animals; Chloral Hydrate; Dichloroacetic Acid; Ethylene Chlorohydrin; Female; Glyoxylates; Humans; Kinetics; Male; Mice; Microsomes, Liver; NADP; Oxalates; Oxalic Acid; Rats; Rats, Inbred F344; Sex Factors; Solvents; Species Specificity; Trichloroethylene | 1998 |
Cardiac teratogenicity of trichloroethylene metabolites.
Topics: Abnormalities, Drug-Induced; Acetaldehyde; Acetates; Animals; Chloral Hydrate; Cystine; Dichloroethylenes; Embryonic and Fetal Development; Environmental Pollutants; Ethylene Chlorohydrin; Female; Heart; Heart Defects, Congenital; Humans; Maternal Exposure; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Teratogens; Trichloroacetic Acid; Trichloroethylene; Water Pollutants, Chemical; Water Supply | 1998 |
The extent of dichloroacetate formation from trichloroethylene, chloral hydrate, trichloroacetate, and trichloroethanol in B6C3F1 mice.
Topics: Animals; Biological Availability; Chloral Hydrate; Dichloroacetic Acid; Ethylene Chlorohydrin; Half-Life; Male; Metabolic Clearance Rate; Mice; Models, Biological; Trichloroacetic Acid; Trichloroethylene | 1998 |
Chloral hydrate enhances ethanol-induced inhibition of methanol oxidation in mice.
Topics: Alcohol Dehydrogenase; Animals; Chloral Hydrate; Drug Combinations; Drug Synergism; Enzyme Inhibitors; Ethanol; Ethylene Chlorohydrin; Half-Life; Liver; Metabolic Clearance Rate; Methanol; Mice; Mice, Inbred Strains; Oxidation-Reduction | 1998 |
Physiologically based pharmacokinetic modeling of inhaled trichloroethylene and its oxidative metabolites in B6C3F1 mice.
Topics: Adipose Tissue; Administration, Inhalation; Animals; Chloral Hydrate; Dichloroacetic Acid; Ethylene Chlorohydrin; Kidney; Liver; Lung; Male; Metabolic Clearance Rate; Mice; Mice, Inbred Strains; Models, Biological; Oxidation-Reduction; Sensitivity and Specificity; Solvents; Tissue Distribution; Trichloroacetic Acid; Trichloroethylene | 1999 |
Perimortem fixation of the gastric and duodenal mucosa: a diagnostic indication for oral poisoning.
Topics: Adult; Chloral Hydrate; Duodenum; Ethylene Chlorohydrin; Gastric Mucosa; Humans; Intestinal Mucosa; Male; Mercury Poisoning; Poisoning; Postmortem Changes; Sensitivity and Specificity; Tissue Fixation | 1999 |
Determination of chloral hydrate metabolites in human plasma by gas chromatography-mass spectrometry.
Topics: Acetals; Acetates; Acidosis, Lactic; Administration, Oral; Child; Chloral Hydrate; Dichloroacetic Acid; Ethylene Chlorohydrin; Evaluation Studies as Topic; Gas Chromatography-Mass Spectrometry; Glucuronates; Glucuronides; Humans; Hydroxamic Acids; Reproducibility of Results; Sensitivity and Specificity; Trichloroacetic Acid | 1999 |
Inhibition by chloral hydrate and trichloroethanol of AMPA-induced Ca(2+) influx in rat cultured cortical neurones.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cells, Cultured; Cerebral Cortex; Chloral Hydrate; Dose-Response Relationship, Drug; Ethylene Chlorohydrin; Fluorometry; Rats; Rats, Wistar | 2000 |
Fatal intoxications with chloral hydrate.
Topics: Adult; Alcoholism; Chloral Hydrate; Drug Overdose; Ethylene Chlorohydrin; Fatal Outcome; Female; Gas Chromatography-Mass Spectrometry; Humans; Hypnotics and Sedatives; Male; Substance-Related Disorders | 2001 |
Binding of the active metabolite of chloral hydrate, 2,2,2-trichloroethanol, to serum albumin demonstrated using tryptophan fluorescence quenching.
Topics: Animals; Cattle; Chloral Hydrate; Circular Dichroism; Ethylene Chlorohydrin; Humans; Hypnotics and Sedatives; Protein Binding; Protein Conformation; Serum Albumin; Spectrometry, Fluorescence; Tryptophan | 2002 |
Trichloroethanol alters action potentials in a subgroup of primary sensory neurones.
Topics: Action Potentials; Anesthetics, Intravenous; Animals; Chloral Hydrate; Ethylene Chlorohydrin; Female; Ganglia, Spinal; Lectins; Male; Nerve Fibers; Neurons, Afferent; Nociceptors; Organ Culture Techniques; Pain; Peptides; Potassium Channels, Calcium-Activated; Rats; Rats, Wistar | 2002 |
Tumorigenicity of chloral hydrate, trichloroacetic acid, trichloroethanol, malondialdehyde, 4-hydroxy-2-nonenal, crotonaldehyde, and acrolein in the B6C3F(1) neonatal mouse.
Topics: Acrolein; Aldehydes; Animals; Animals, Newborn; Carcinogenicity Tests; Carcinogens; Chloral Hydrate; Chromatography, High Pressure Liquid; Crosses, Genetic; DNA; DNA Adducts; Electrochemistry; Ethylene Chlorohydrin; Female; Lipid Peroxidation; Liver; Liver Neoplasms, Experimental; Male; Malondialdehyde; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Microsomes, Liver; Phosphorus Radioisotopes; Trichloroacetic Acid | 2002 |
Metabolism and toxicity of trichloroethylene in epididymis and testis.
Topics: Administration, Inhalation; Animals; Blotting, Western; Chloral Hydrate; Cytochrome P-450 CYP2E1; Epididymis; Ethylene Chlorohydrin; Immunohistochemistry; Male; Mice; Microsomes; Occupational Exposure; Testis; Trichloroacetic Acid; Trichloroethylene | 2002 |
Guinea pig maximization test for trichloroethylene and its metabolites.
Topics: Allergens; Animals; Chloral Hydrate; Dermatitis, Allergic Contact; Dermatitis, Irritant; Ethylene Chlorohydrin; Guinea Pigs; Skin; Toxicity Tests; Trichloroacetic Acid; Trichloroethylene | 2002 |
Absorption, excretion and metabolic fate of chloral hydrate and trichloroethanol.
Topics: Biological Transport; Body Fluids; Chloral Hydrate; Ethanol; Ethylene Chlorohydrin; Humans | 1954 |
A comparative evaluation of the hypnotic potency of chloral hydrate and trichloroethanol. I. Studies at the Johns Hopkins University School of Medicine. II. Studies at the St. Louis University School of Medicine. III. Studies at Harvard Medical School.
Topics: Chloral Hydrate; Ethanol; Ethylene Chlorohydrin; Humans; Hypnotics and Sedatives; Medicine; Schools, Medical; Universities | 1955 |
Further studies on the metabolic fate of chloral hydrate and trichloroethanol.
Topics: Biochemical Phenomena; Blood; Chloral Hydrate; Ethanol; Ethylene Chlorohydrin; Humans; Trichloroacetic Acid; Trichloroethylene | 1955 |
Anticholinesterase and anticurare effects of chloral hydrate and trichloroethanol.
Topics: Chloral Hydrate; Cholinesterase Inhibitors; Curare; Ethanol; Ethylene Chlorohydrin; Humans | 1955 |
An eserine-like action of chloral hydrate.
Topics: Acetylcholine; Action Potentials; Animals; Carbachol; Cats; Chloral Hydrate; Cholinesterase Inhibitors; Ethylene Chlorohydrin; Ganglia; Injections, Intra-Arterial; Neostigmine; Nicotine; Physostigmine; Quaternary Ammonium Compounds; Rabbits; Rats | 1962 |
Exposure to trichloroethylene and its metabolites causes impairment of sperm fertilizing ability in mice.
Topics: Acrosome Reaction; Anesthetics, Intravenous; Animals; Body Weight; Chloral Hydrate; Epididymis; Ethylene Chlorohydrin; Female; Fertilization; Fertilization in Vitro; In Vitro Techniques; Inhalation Exposure; Male; Mice; Organ Size; Solvents; Sperm Count; Sperm Motility; Sperm-Ovum Interactions; Spermatozoa; Testis; Trichloroethylene | 2004 |
Application of cryopreserved human hepatocytes in trichloroethylene risk assessment: relative disposition of chloral hydrate to trichloroacetate and trichloroethanol.
Topics: Adult; Aged; Alcohol Dehydrogenase; Aldehyde Dehydrogenase; Animals; Chloral Hydrate; Cryopreservation; Ethylene Chlorohydrin; Female; Genotype; Hepatocytes; Humans; In Vitro Techniques; Kinetics; Male; Middle Aged; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Risk Assessment; Solvents; Trichloroacetic Acid; Trichloroethylene | 2006 |
Bayesian population analysis of a harmonized physiologically based pharmacokinetic model of trichloroethylene and its metabolites.
Topics: Animals; Bayes Theorem; Chloral Hydrate; Dichloroacetic Acid; Dose-Response Relationship, Drug; Ethylene Chlorohydrin; Humans; Kinetics; Markov Chains; Mice; Models, Biological; Monte Carlo Method; Rats; Sulfhydryl Compounds; Trichloroacetic Acid; Trichloroethylene | 2006 |
Lack of formic acid production in rat hepatocytes and human renal proximal tubule cells exposed to chloral hydrate or trichloroacetic acid.
Topics: Adolescent; Adult; Animals; Chemical and Drug Induced Liver Injury; Chloral Hydrate; Chromatography, Gas; Ethylene Chlorohydrin; Formates; Hepatocytes; Humans; Kidney Diseases; Kidney Tubules, Proximal; Liver Diseases; Magnetic Resonance Spectroscopy; Male; Rats; Trichloroacetic Acid | 2007 |
Kinetics of chloral hydrate and its metabolites in male human volunteers.
Topics: Adult; Chloral Hydrate; Dichloroacetic Acid; Ethylene Chlorohydrin; Glucuronates; Humans; Liver; Male; Middle Aged; Time Factors; Trichloroacetic Acid | 2008 |
An unusual trichloroethanol fatality attributed to sniffing trichloroethylene.
Topics: Administration, Inhalation; Adult; Cause of Death; Chloral Hydrate; Chromatography, Gas; Ethylene Chlorohydrin; Fatal Outcome; Forensic Toxicology; Humans; Inhalation Exposure; Male; Substance Abuse Detection; Substance-Related Disorders | 2008 |
False-positive ethyl glucuronide immunoassay screening associated with chloral hydrate medication as confirmed by LC-MS/MS and self-medication.
Topics: Adult; Biomarkers; Chloral Hydrate; Chromatography, Liquid; Cross Reactions; Ethylene Chlorohydrin; False Positive Reactions; Female; Forensic Toxicology; Glucuronates; Humans; Hypnotics and Sedatives; Immunoassay; Mass Spectrometry; Self Medication; Trichloroacetic Acid | 2009 |
Chloral hydrate intoxication in a 3-month-old child: avoidance of hemodialysis by an immediate determination of trichloroethanol.
Topics: Adult; Chloral Hydrate; Ethylene Chlorohydrin; Humans; Hypnotics and Sedatives; Infant; Mass Spectrometry; Renal Dialysis | 2010 |
2,2,2-Trichloroethanol lengthens the circadian period of Bmal1-driven circadian bioluminescence rhythms in U2OS cells.
Topics: Animals; ARNTL Transcription Factors; Cell Line; Chloral Hydrate; Circadian Rhythm; CLOCK Proteins; Ethylene Chlorohydrin; Humans; Hypnotics and Sedatives; Luminescent Measurements; Male; Mice; Nuclear Receptor Subfamily 1, Group D, Member 1; Period Circadian Proteins; Rats; Rats, Inbred F344 | 2015 |
Simple method to detect triclofos and its metabolites in plasma of children by combined use of liquid chromatography tandem-mass spectrometry and gas chromatography-mass spectrometry.
Topics: Child, Preschool; Chloral Hydrate; Chromatography, Liquid; Ethylene Chlorohydrin; Female; Gas Chromatography-Mass Spectrometry; Humans; Hydrolysis; Hypnotics and Sedatives; Infant; Japan; Limit of Detection; Male; Mass Spectrometry; Organophosphates; Reproducibility of Results; Tandem Mass Spectrometry; Trichloroacetic Acid | 2019 |
Trichloroethanol, an active metabolite of chloral hydrate, modulates tetrodotoxin-resistant Na
Topics: Animals; Chloral Hydrate; Ganglia, Spinal; Membrane Potentials; Nociceptors; Rats; Rats, Sprague-Dawley; Sodium Channels; Tetrodotoxin | 2023 |