Compounds > 2-2--azino-di-(3-ethylbenzothiazoline)-6-sulfonic-acid

2-2--azino-di-(3-ethylbenzothiazoline)-6-sulfonic-acid and sulfuryl-fluoride

2-2--azino-di-(3-ethylbenzothiazoline)-6-sulfonic-acid has been researched along with sulfuryl-fluoride* in 1 studies

Other Studies

1 other study(ies) available for 2-2--azino-di-(3-ethylbenzothiazoline)-6-sulfonic-acid and sulfuryl-fluoride

Article	Year
Radical scavenging and anti-inflammatory activities of (hetero)arylethenesulfonyl fluorides: Synthesis and structure-activity relationship (SAR) and QSAR studies. Bioorganic chemistry, 2019, Volume: 89 A series of (hetero)arylethenesulfonyl fluorides (1-58) were synthesized and screened for their in vitro antioxidant (DPPH, ABTS and DMPD methods) and anti-inflammatory activities. The results revealed that compounds 4, 15, 16, 24, 25, 26, 38, 39, 40, and 54 exhibited excellent antioxidant activity using all the three performed antioxidant methods, which were superior to the standard antioxidants ascorbic acid and gallic acid. Compounds 6-9, 11, 18, 19, 21, 22, 30, 39, 40, 44, 45, 48-50, 54, 55 and 57 displayed promising anti-inflammatory activity, which were better than the reference drug indomethacin. Preliminary structure-activity relationship (SAR) revealed that compounds containing electron donating (OH and OCH Topics: Anti-Inflammatory Agents, Non-Steroidal; Benzothiazoles; Biphenyl Compounds; Dose-Response Relationship, Drug; Erythrocytes; Ethylenes; Free Radical Scavengers; Humans; Molecular Structure; Phenylenediamines; Picrates; Structure-Activity Relationship; Sulfinic Acids; Sulfonic Acids	2019

Article

Year

Radical scavenging and anti-inflammatory activities of (hetero)arylethenesulfonyl fluorides: Synthesis and structure-activity relationship (SAR) and QSAR studies.

Bioorganic chemistry, 2019, Volume: 89

A series of (hetero)arylethenesulfonyl fluorides (1-58) were synthesized and screened for their in vitro antioxidant (DPPH, ABTS and DMPD methods) and anti-inflammatory activities. The results revealed that compounds 4, 15, 16, 24, 25, 26, 38, 39, 40, and 54 exhibited excellent antioxidant activity using all the three performed antioxidant methods, which were superior to the standard antioxidants ascorbic acid and gallic acid. Compounds 6-9, 11, 18, 19, 21, 22, 30, 39, 40, 44, 45, 48-50, 54, 55 and 57 displayed promising anti-inflammatory activity, which were better than the reference drug indomethacin. Preliminary structure-activity relationship (SAR) revealed that compounds containing electron donating (OH and OCH

Topics: Anti-Inflammatory Agents, Non-Steroidal; Benzothiazoles; Biphenyl Compounds; Dose-Response Relationship, Drug; Erythrocytes; Ethylenes; Free Radical Scavengers; Humans; Molecular Structure; Phenylenediamines; Picrates; Structure-Activity Relationship; Sulfinic Acids; Sulfonic Acids

2019