Page last updated: 2024-08-26

2,2',4,4'-tetrabromodiphenyl ether and thyroxine

2,2',4,4'-tetrabromodiphenyl ether has been researched along with thyroxine in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's8 (40.00)29.6817
2010's9 (45.00)24.3611
2020's3 (15.00)2.80

Authors

AuthorsStudies
Crofton, KM; DeVito, MJ; Taylor, MM; Zhou, T1
Darnerud, PO; Hallgren, S1
Aune, M; Darnerud, PO; Hallgren, S; Larsson, L1
Birnbaum, LS; DeVito, MJ; Diliberto, JJ; Richardson, VM; Ross, DG; Staskal, DF1
Bergman, A; Brouwer, A; Hamers, T; Kamstra, JH; Murk, AJ; Sonneveld, E; Van Velzen, MJ; Visser, TJ1
Gee, JR; Hedge, JM; Moser, VC1
Abdelouahab, N; Langlois, MF; Pasquier, JC; Praud, JP; Suvorov, A; Takser, L1
Fang, D; Huang, H; Jiang, Y; Liu, J; Liu, Z; Mei, S; Tian, Y; Zhang, H; Zhang, J; Zhou, J1
Dai, J; Jin, Y; Liu, W; Liu, X; Ma, J; Wang, F; Xie, Q; Yu, W; Zhao, H1
Bergman, A; Cocco, E; Guignard, C; Gutleb, AC; Hoffmann, L; Marsh, G; Montaño, M; Murk, AJ1
Li, D; Ren, X; Wang, S; You, H; Zhao, X1
Draugelis-Dale, RO; Eilts, BE; Goodbred, SL; Jenkins, JA; Nilsen, E; Olivier, HM; Patiño, R; Torres, L1
Eisenreich, KM; Rowe, CL1
Miao, J; Pan, L; Song, Y; Wang, X1
Arkoosh, MR; Dietrich, JP; Hutchinson, GP; Krupkin, AB; Strickland, SA; Van Gaest, AL1
Faiola, F; Liang, S; Yin, N1
Chen, A; Ji, H; Liang, H; Miao, M; Sun, X; Wang, X; Wang, Z; Wen, S; Yuan, W; Zhang, X1
Chen, C; Chen, H; Gong, X; Hu, Y; Ji, M; Shen, J; Wang, C; Wang, SL; Xia, R; Yu, Y; Zhang, Z; Zhu, J1
Chi, Q; Huang, J; Wang, L; Wang, X; Xiao, H; Yuan, M; Zhang, W1
Brito, PM; de Almeida Roque, A; de Oliveira Ribeiro, CA; de Oliveira, EC; Esquivel, L; Fávaro, LF; Filipak Neto, F; Folle, NMT; Garcia, JRE; Leão-Buchir, J; Lima de Souza, T; Mela Prodocimo, M; Ramsdorf, WA1

Other Studies

20 other study(ies) available for 2,2',4,4'-tetrabromodiphenyl ether and thyroxine

ArticleYear
Developmental exposure to brominated diphenyl ethers results in thyroid hormone disruption.
    Toxicological sciences : an official journal of the Society of Toxicology, 2002, Volume: 66, Issue:1

    Topics: Animals; Body Weight; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2B1; Female; Glucuronosyltransferase; Halogenated Diphenyl Ethers; Hydrocarbons, Brominated; Liver; Maternal Exposure; Microsomes, Liver; No-Observed-Adverse-Effect Level; Organ Size; Phenyl Ethers; Polybrominated Biphenyls; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Long-Evans; Reproduction; Thyroid Hormones; Thyroxine; Time Factors; Triiodothyronine

2002
Polybrominated diphenyl ethers (PBDEs), polychlorinated biphenyls (PCBs) and chlorinated paraffins (CPs) in rats-testing interactions and mechanisms for thyroid hormone effects.
    Toxicology, 2002, Aug-15, Volume: 177, Issue:2-3

    Topics: Animals; Blood Proteins; Body Weight; Chlorodiphenyl (54% Chlorine); Cytochrome P-450 CYP1A1; Enzyme Induction; Female; Glucuronosyltransferase; Halogenated Diphenyl Ethers; Hydrocarbons, Brominated; Organ Size; Paraffin; Phenyl Ethers; Polybrominated Biphenyls; Protein Binding; Rats; Rats, Sprague-Dawley; Thyroid Gland; Thyroxine

2002
Plasma PBDE and thyroxine levels in rats exposed to Bromkal or BDE-47.
    Chemosphere, 2007, Volume: 67, Issue:9

    Topics: Animals; Body Weight; Dose-Response Relationship, Drug; Environmental Exposure; Female; Flame Retardants; Halogenated Diphenyl Ethers; Humans; Hydrocarbons, Brominated; Phenyl Ethers; Polybrominated Biphenyls; Rats; Rats, Sprague-Dawley; Risk Assessment; Thyroxine; Time Factors

2007
Possible mechanisms of thyroid hormone disruption in mice by BDE 47, a major polybrominated diphenyl ether congener.
    Toxicology and applied pharmacology, 2008, Feb-01, Volume: 226, Issue:3

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Transporters; Cytochrome P-450 CYP2B1; Cytochrome P450 Family 2; Dose-Response Relationship, Drug; Endocrine Disruptors; Environmental Pollutants; Enzyme Induction; Female; Flame Retardants; Gene Expression Regulation, Enzymologic; Glucuronosyltransferase; Halogenated Diphenyl Ethers; Liver; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Monocarboxylic Acid Transporters; Polybrominated Biphenyls; Prealbumin; Protein Kinases; RNA, Messenger; Steroid Hydroxylases; Symporters; Thyroid Gland; Thyroxine

2008
Biotransformation of brominated flame retardants into potentially endocrine-disrupting metabolites, with special attention to 2,2',4,4'-tetrabromodiphenyl ether (BDE-47).
    Molecular nutrition & food research, 2008, Volume: 52, Issue:2

    Topics: Animals; Binding, Competitive; Cell Division; Cytochrome P-450 Enzyme System; Endocrine Disruptors; Enzyme Inhibitors; Estradiol; Flame Retardants; Halogenated Diphenyl Ethers; Hydroxylation; Male; Microsomes, Liver; NADP; Phenobarbital; Polybrominated Biphenyls; Prealbumin; Rats; Rats, Wistar; Sulfotransferases; Thyroxine

2008
Lack of alterations in thyroid hormones following exposure to polybrominated diphenyl ether 47 during a period of rapid brain development in mice.
    Drug and chemical toxicology, 2008, Volume: 31, Issue:2

    Topics: Animals; Behavior, Animal; Body Weight; Brain; Halogenated Diphenyl Ethers; Hydrocarbons, Brominated; Male; Mice; Mice, Inbred C57BL; Phenyl Ethers; Thyroxine; Time Factors; Triiodothyronine

2008
Thyroid disruption by low-dose BDE-47 in prenatally exposed lambs.
    Neonatology, 2009, Volume: 96, Issue:2

    Topics: Adipose Tissue; Animals; Animals, Newborn; Embryo, Mammalian; Environmental Pollutants; Female; Gestational Age; Halogenated Diphenyl Ethers; Maternal Exposure; Polybrominated Biphenyls; Pregnancy; Sheep; Thyroid Gland; Thyroxine; Triiodothyronine

2009
[Effects and toxicity mechanism of 2,2',4,4'-tetrabrominated diphenyl ethers on the homeostasis of thyroid hormone system in C57BL/6 mice].
    Wei sheng yan jiu = Journal of hygiene research, 2009, Volume: 38, Issue:5

    Topics: Animals; Female; Halogenated Diphenyl Ethers; Homeostasis; Iodide Peroxidase; Male; Mice; Mice, Inbred C57BL; Thyroid Hormones; Thyrotropin; Thyroxine; Triiodothyronine

2009
Interaction of PFOS and BDE-47 co-exposure on thyroid hormone levels and TH-related gene and protein expression in developing rat brains.
    Toxicological sciences : an official journal of the Society of Toxicology, 2011, Volume: 121, Issue:2

    Topics: Alkanesulfonic Acids; Animals; Animals, Newborn; Brain-Derived Neurotrophic Factor; Drug Interactions; Female; Fluorocarbons; GAP-43 Protein; Gene Expression Regulation, Developmental; Halogenated Diphenyl Ethers; Kruppel-Like Transcription Factors; Male; Neural Cell Adhesion Molecules; Polybrominated Biphenyls; Polymerase Chain Reaction; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; RNA, Messenger; Thyroid Gland; Thyroid Hormones; Thyroxine; Triiodothyronine

2011
New approaches to assess the transthyretin binding capacity of bioactivated thyroid hormone disruptors.
    Toxicological sciences : an official journal of the Society of Toxicology, 2012, Volume: 130, Issue:1

    Topics: Animals; Cholesterol; Chromatography, High Pressure Liquid; Endocrine Disruptors; Environmental Pollutants; Fatty Acids; Fatty Acids, Unsaturated; Halogenated Diphenyl Ethers; Microsomes, Liver; Polybrominated Biphenyls; Polychlorinated Biphenyls; Prealbumin; Protein Binding; Rats; Rats, Sprague-Dawley; Thyroxine

2012
Effects of perchlorate on BDE-47-induced alteration thyroid hormone and gene expression of in the hypothalamus-pituitary-thyroid axis in zebrafish larvae.
    Environmental toxicology and pharmacology, 2013, Volume: 36, Issue:3

    Topics: Animals; Blotting, Western; Environmental Monitoring; Flame Retardants; Gene Expression; Halogenated Diphenyl Ethers; Hypothalamo-Hypophyseal System; Larva; Perchlorates; Pituitary Gland; Real-Time Polymerase Chain Reaction; RNA; Teratogens; Thyroid Gland; Thyroid Hormones; Thyroxine; Triiodothyronine; Zebrafish

2013
Assessing reproductive and endocrine parameters in male largescale suckers (Catostomus macrocheilus) along a contaminant gradient in the lower Columbia River, USA.
    The Science of the total environment, 2014, Jun-15, Volume: 484

    Topics: Animals; Cypriniformes; Dichlorodiphenyl Dichloroethylene; Endocrine Disruptors; Environmental Monitoring; Halogenated Diphenyl Ethers; Humans; Male; Polybrominated Biphenyls; Polychlorinated Biphenyls; Reproduction; Rivers; Thyroxine; Vitellogenins; Water Pollutants, Chemical

2014
Dietary exposure of BDE-47 and BDE-99 and effects on behavior, bioenergetics, and thyroid function in juvenile red-eared sliders (Trachemys scripta elegans) and common snapping turtles (Chelydra serpentina).
    Environmental toxicology and chemistry, 2014, Volume: 33, Issue:12

    Topics: Animals; Behavior, Animal; Energy Metabolism; Environmental Exposure; Gas Chromatography-Mass Spectrometry; Halogenated Diphenyl Ethers; Thyroid Gland; Thyroxine; Turtles

2014
Exposure to2,2',4,4'-tetrabromodiphenyl ether (BDE-47) alters thyroid hormone levels and thyroid hormone-regulated gene transcription in manila clam Ruditapes philippinarum.
    Chemosphere, 2016, Volume: 152

    Topics: Animals; Bivalvia; Gene Expression Regulation; Halogenated Diphenyl Ethers; Iodide Peroxidase; Thyroxine; Triiodothyronine; Water Pollutants, Chemical

2016
Alteration of thyroid hormone concentrations in juvenile Chinook salmon (Oncorhynchus tshawytscha) exposed to polybrominated diphenyl ethers, BDE-47 and BDE-99.
    Chemosphere, 2017, Volume: 171

    Topics: Animals; Diet; Halogenated Diphenyl Ethers; Salmon; Thyroid Hormones; Thyroxine; Triiodothyronine

2017
Establishment of a human embryonic stem cell-based liver differentiation model for hepatotoxicity evaluations.
    Ecotoxicology and environmental safety, 2019, Jun-15, Volume: 174

    Topics: Animals; Cell Differentiation; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Embryonic Development; Endocrine Disruptors; Environmental Pollutants; Female; Halogenated Diphenyl Ethers; Hepatocytes; Human Embryonic Stem Cells; Humans; Models, Biological; Pregnancy; Thyroxine; Transcriptome; Triiodothyronine

2019
Associations of prenatal exposures to low levels of Polybrominated Diphenyl Ether (PBDE) with thyroid hormones in cord plasma and neurobehavioral development in children at 2 and 4 years.
    Environment international, 2019, Volume: 131

    Topics: Child, Preschool; China; Cohort Studies; Female; Fetal Blood; Halogenated Diphenyl Ethers; Humans; Infant; Male; Pregnancy; Prenatal Exposure Delayed Effects; Thyroid Function Tests; Thyroid Hormones; Thyrotropin; Thyroxine

2019
Rno-miR-224-5p contributes to 2,2',4,4'-tetrabromodiphenyl ether-induced low triiodothyronine in rats by targeting deiodinases.
    Chemosphere, 2020, Volume: 246

    Topics: Animals; Environmental Pollutants; Ether; Halogenated Diphenyl Ethers; Humans; Hypothyroidism; Iodide Peroxidase; MicroRNAs; Rats; Thyroid Hormones; Thyroxine; Triiodothyronine

2020
Evaluation of structurally different brominated flame retardants interacting with the transthyretin and their toxicity on HepG2 cells.
    Chemosphere, 2020, Volume: 246

    Topics: Animals; Animals, Wild; Binding, Competitive; Endocrine Disruptors; Flame Retardants; Halogenated Diphenyl Ethers; Hep G2 Cells; Humans; Hydrocarbons, Brominated; Molecular Docking Simulation; Polybrominated Biphenyls; Prealbumin; Thyroxine; Toxicity Tests

2020
Effects of trophic 2,2', 4,4'-tetrabromodiphenyl ether (BDE-47) exposure in Oreochromis niloticus: A multiple biomarkers analysis.
    Environmental toxicology and pharmacology, 2021, Volume: 87

    Topics: Acetylcholinesterase; Administration, Oral; Animals; Biomarkers; Brain; Cichlids; Estradiol; Female; Glutathione Transferase; Gonads; Halogenated Diphenyl Ethers; Kidney; Liver; Male; Muscles; Thyrotropin; Thyroxine; Vitellogenins; Water Pollutants, Chemical

2021