Page last updated: 2024-09-04

2'-o-methylcytidine and 2'-o-methylguanosine

2'-o-methylcytidine has been researched along with 2'-o-methylguanosine in 5 studies

Compound Research Comparison

Studies
(2'-o-methylcytidine)
Trials
(2'-o-methylcytidine)
Recent Studies (post-2010)
(2'-o-methylcytidine)
Studies
(2'-o-methylguanosine)
Trials
(2'-o-methylguanosine)
Recent Studies (post-2010) (2'-o-methylguanosine)
16072307

Protein Interaction Comparison

ProteinTaxonomy2'-o-methylcytidine (IC50)2'-o-methylguanosine (IC50)
RNA-directed RNA polymerase 1.6

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's3 (60.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bhat, B; Carroll, SS; Cook, PD; Eldrup, AB; Galloway, SM; Hilliard, C; MacCoss, M; Olsen, DB; Prakash, TP; Prhavc, M; Stahlhut, MW; Tomassini, JE1
Mayhoub, AS1
Agris, PF; Mucha, P; Rekowski, P; Szyk, A; Weiss, PA1
Guan, Y; Shang, H; Tong, Z; Zhao, B; Zhao, G1
Jones, JD; Kennedy, RT; Koutmou, KS; Lin, Q; Tardu, M1

Reviews

1 review(s) available for 2'-o-methylcytidine and 2'-o-methylguanosine

ArticleYear
Hepatitis C RNA-dependent RNA polymerase inhibitors: a review of structure-activity and resistance relationships; different scaffolds and mutations.
    Bioorganic & medicinal chemistry, 2012, May-15, Volume: 20, Issue:10

    Topics: Drug Design; Enzyme Activation; Enzyme Inhibitors; Hepacivirus; Humans; Mutation; RNA-Dependent RNA Polymerase; Viral Nonstructural Proteins

2012

Other Studies

4 other study(ies) available for 2'-o-methylcytidine and 2'-o-methylguanosine

ArticleYear
Synthesis and evaluation of S-acyl-2-thioethyl esters of modified nucleoside 5'-monophosphates as inhibitors of hepatitis C virus RNA replication.
    Journal of medicinal chemistry, 2005, Feb-24, Volume: 48, Issue:4

    Topics: Animals; Cell Line, Tumor; CHO Cells; Chromosome Aberrations; Cricetinae; Cricetulus; Cytidine; Cytidine Monophosphate; Hepacivirus; Humans; Organophosphates; Prodrugs; RNA-Dependent RNA Polymerase; RNA, Viral; Tritium; Viral Nonstructural Proteins; Virus Replication

2005
Anticodon domain methylated nucleosides of yeast tRNA(Phe) are significant recognition determinants in the binding of a phage display selected peptide.
    Biochemistry, 2001, Nov-27, Volume: 40, Issue:47

    Topics: Anticodon; Binding Sites; Cytidine; Guanosine; Models, Chemical; Nucleic Acid Conformation; Nucleosides; Peptide Library; Peptides; Protein Binding; RNA, Fungal; RNA, Transfer, Phe

2001
2'-O-methyl nucleotide modified DNA substrates influence the cleavage efficiencies of BamHI and BglII.
    Journal of biosciences, 2014, Volume: 39, Issue:4

    Topics: Adenosine; Bacterial Proteins; Cytidine; Deoxyribonuclease BamHI; Deoxyribonucleases, Type II Site-Specific; DNA; DNA Cleavage; Fluorescence Resonance Energy Transfer; Guanosine; Kinetics; Oligonucleotides; Thymidine

2014
Identification and Quantification of Modified Nucleosides in
    ACS chemical biology, 2019, 07-19, Volume: 14, Issue:7

    Topics: Adenosine; Cytidine; Glucose; Guanosine; Heat-Shock Response; Nucleosides; Oxidative Stress; RNA, Fungal; RNA, Messenger; Saccharomyces cerevisiae

2019