2'-methyl-2'-deoxycytidine has been researched along with fluorouracil in 1 studies
*Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid. [MeSH]
*Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid. [MeSH]
| Studies (2'-methyl-2'-deoxycytidine) | Trials (2'-methyl-2'-deoxycytidine) | Recent Studies (post-2010) (2'-methyl-2'-deoxycytidine) | Studies (fluorouracil) | Trials (fluorouracil) | Recent Studies (post-2010) (fluorouracil) |
|---|---|---|---|---|---|
| 8 | 0 | 2 | 45,562 | 9,307 | 14,663 |
| Protein | Taxonomy | 2'-methyl-2'-deoxycytidine (IC50) | fluorouracil (IC50) |
|---|---|---|---|
| Epidermal growth factor receptor | Homo sapiens (human) | 0.32 | |
| Thymidylate synthase | Mus musculus (house mouse) | 1.58 | |
| Aromatase | Homo sapiens (human) | 0.63 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Matsuda, A; Sasaki, T; Takenuki, K; Ueda, T | 1 |
1 other study(ies) available for 2'-methyl-2'-deoxycytidine and fluorouracil
| Article | Year |
|---|---|
Nucleosides and nucleotides. 94. Radical deoxygenation of tert-alcohols in 1-(2-C-alkylpentofuranosyl) pyrimidines: synthesis of (2'S)-2'-deoxy-2'-C-methylcytidine, an antileukemic nucleoside.
Topics: Animals; Antimetabolites, Antineoplastic; Deoxycytidine; Drug Screening Assays, Antitumor; Humans; Indicators and Reagents; Leukemia; Leukemia L1210; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mice; Molecular Structure; Neoplasms; Structure-Activity Relationship | 1991 |