Page last updated: 2024-09-04

2'-hydroxyflavone and flavone

2'-hydroxyflavone has been researched along with flavone in 4 studies

Compound Research Comparison

Studies
(2'-hydroxyflavone)
Trials
(2'-hydroxyflavone)
Recent Studies (post-2010)
(2'-hydroxyflavone)
Studies
(flavone)
Trials
(flavone)
Recent Studies (post-2010) (flavone)
10045661268

Protein Interaction Comparison

ProteinTaxonomy2'-hydroxyflavone (IC50)flavone (IC50)
Poly [ADP-ribose] polymerase tankyrase-1Homo sapiens (human)0.3243
Poly [ADP-ribose] polymerase 1Homo sapiens (human)1.3902
Androgen receptorHomo sapiens (human)5.9
AromataseHomo sapiens (human)6.0027
Dipeptidyl peptidase 4Homo sapiens (human)0.17
Cytochrome P450 1B1Homo sapiens (human)0.6
Poly [ADP-ribose] polymerase tankyrase-2Homo sapiens (human)0.144

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's1 (25.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ares, JJ; Ems, BL; Kakodkar, SV; Kelm, GR; Kershaw, WC; Murray, PD; O'Brien, LM; Outt, PE; Randall, JL; Weisshaar, PS1
Autino, JC; Bennardi, DO; Castro, EA; Duchowicz, PR; Romanelli, GP; Vitale, MG1
Chan, CB; France, S; He, K; Huang, J; Jang, SW; Jia, Y; Liu, X; Luo, HR; Phun, LH; Pradoldej, S; Xiao, G; Ye, K1
Bhakat, S; Ciftci-Yabanoglu, S; Jayaprakash, V; Nayak, BV; Sinha, BN; Soliman, ME; Timiri, AK; Ucar, G1

Other Studies

4 other study(ies) available for 2'-hydroxyflavone and flavone

ArticleYear
Synthesis and biological evaluation of substituted flavones as gastroprotective agents.
    Journal of medicinal chemistry, 1995, Dec-08, Volume: 38, Issue:25

    Topics: Animals; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Enzyme Induction; Ethanol; Flavonoids; Indomethacin; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Microsomes, Liver; Oxidoreductases; Rats; Rats, Sprague-Dawley; Stomach Diseases; Structure-Activity Relationship

1995
QSAR modeling of the interaction of flavonoids with GABA(A) receptor.
    European journal of medicinal chemistry, 2008, Volume: 43, Issue:8

    Topics: Binding Sites; Flavonoids; Molecular Structure; Protein Binding; Quantitative Structure-Activity Relationship; Receptors, GABA-A

2008
A synthetic 7,8-dihydroxyflavone derivative promotes neurogenesis and exhibits potent antidepressant effect.
    Journal of medicinal chemistry, 2010, Dec-09, Volume: 53, Issue:23

    Topics: Animals; Antidepressive Agents; Apoptosis; Flavones; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Inbred C57BL; Neurogenesis; Spectrometry, Mass, Electrospray Ionization; Structure-Activity Relationship

2010
Monoamine oxidase inhibitory activity of 2-aryl-4H-chromen-4-ones.
    Bioorganic chemistry, 2015, Volume: 58

    Topics: Benzopyrans; Kinetics; Molecular Docking Simulation; Monoamine Oxidase Inhibitors; Proton Magnetic Resonance Spectroscopy; Spectrometry, Mass, Electrospray Ionization

2015