2--hydroxychalcone has been researched along with cyclohexene* in 2 studies
2 other study(ies) available for 2--hydroxychalcone and cyclohexene
| Article | Year |
|---|---|
Chiral Boron Complex-Promoted Asymmetric Diels-Alder Cycloaddition and Its Application in Natural Product Synthesis.
An efficient method for the asymmetric Diels-Alder cycloaddition of 2'-hydroxychalcones with acyclic or cyclic dienes has been successfully developed. The Diels-Alder cycloaddition is mediated by a chiral boron complex with VANOL, affording the corresponding products in high yields and with excellent diastereo- and enantioselectivities. This reaction enabled the enantioselective construction of cyclohexene skeletons crucial for the total synthesis of a number of Diels-Alder-type natural products (-)-nicolaioidesin C, (-)-panduratine A, (-)-kuwanon I, (+)-kuwanon J, and (-)-brosimones A and B. Topics: Biological Products; Boron Compounds; Chalcones; Cycloaddition Reaction; Cyclohexenes; Stereoisomerism | 2016 |
Total Synthesis of (±)-Kuwanol E.
The total synthesis of the Diels-Alder-type adducts (±)-kuwanol E and the heptamethyl ether derivative of (±)-kuwanon Y has been accomplished via a convergent strategy involving 2'-hydroxychalcone 6 or 9 and dehydroprenylstilbene 7, in nine steps. The synthesis features, as a key step, a Lewis acid-mediated biomimetic intermolecular Diels-Alder [4+2] cycloaddition for the construction of the cyclohexene skeleton with three stereogenic centers. Notably, the endo/exo diastereoselectivity of the reaction proved to be temperature-controlled. Topics: Chalcones; Cyclohexenes; Flavonoids; Models, Molecular; Molecular Structure; Stereoisomerism; Temperature | 2016 |