2'-fluorothymidine has been researched along with guanine in 26 studies
| Studies (2'-fluorothymidine) | Trials (2'-fluorothymidine) | Recent Studies (post-2010) (2'-fluorothymidine) | Studies (guanine) | Trials (guanine) | Recent Studies (post-2010) (guanine) |
|---|---|---|---|---|---|
| 187 | 18 | 39 | 16,278 | 822 | 4,809 |
| Protein | Taxonomy | 2'-fluorothymidine (IC50) | guanine (IC50) |
|---|---|---|---|
| Purine nucleoside phosphorylase | Homo sapiens (human) | 5 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (3.85) | 18.2507 |
| 2000's | 9 (34.62) | 29.6817 |
| 2010's | 16 (61.54) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cheng, YC; Fu, L; Liu, SH | 1 |
| Boyer, N; Castelneau, C; Marcellin, P | 1 |
| Buti, M; Esteban, R | 2 |
| Hadziyannis, SJ; Papatheodoridis, GV | 1 |
| Avci, A; Erhardt, A; Häussinger, D; Heintges, T; Lörke, J; Sagir, A | 1 |
| Lok, AS | 1 |
| Alauddin, MM; Conti, PS; Gordon, EM; Shahinian, A | 1 |
| Cheong, JY | 1 |
| Yim, HJ | 1 |
| Cho, YK; Jeon, WK; Kim, BI; Kim, HJ; Park, DI; Park, JH; Sohn, CI | 1 |
| Bao, H; Furman, PA; Korba, B; Micolochick Steuer, HM; Murakami, E; Niu, C; Tolstykh, T | 1 |
| Bae, SH; Baek, YH; Han, SY; Lee, SW | 1 |
| Auerbach, MS; Campbell, DO; Czernin, J; Herschman, H; Lavie, A; Lee, JT; Radu, CG; Satyamurthy, N; Su, Y; Yaghoubi, SS | 1 |
| Choi, BS; Choi, SR; Chung, BH; Hong, YA; Kim, YS; Park, CW; Park, HS; Sun, IO; Yang, CW | 1 |
| Chae, HB; Kang, HY; Kang, YW; Kim, AN; Kim, HS; Kim, SB; Kim, SH; Kim, YM; Lee, BS; Lee, ES; Lee, HIe; Lee, HY; Lee, SH; Lee, TH; Noh, R; Song, IH; Yang, HY | 1 |
| Choi, DJ; Jung, YK; Kim, JH; Kim, YS; Kwon, OS; Lee, JJ; Lee, JW; Lee, YJ | 1 |
| Tak, WY | 1 |
| Delaney, W; Furman, P; Hu, J; Jones, SA; Murakami, E | 1 |
| Cho, HC; Cho, JY; Choi, MS; Gwak, GY; Koh, KC; Lee, JH; Paik, SW; Paik, YH; Sohn, W; Yoo, BC | 1 |
| Jang, JY; Kim, BH; Kim, JW; Lee, CK; Shim, JJ | 1 |
| Berg, T; van Bömmel, F | 1 |
| Hwang, JH; Jang, ES; Jeong, SH; Kim, JW; Kim, N; Lee, DH; Lee, SS; Min, BY; Park, YS; Seong, MH; Shin, CM; Sohn, HR; Song, JC | 1 |
| Ahn, SH; Chong, Y; Kang, HS; Kim, BK; Kim, DH; Kim, KH; Lee, AR; Park, ES; Park, S; Park, YK; Rhee, JK; Shin, GC; Yang, SI | 1 |
| Ahn, SH; Cho, EY; Hwang, SG; Jeong, SH; Jung, YK; Kim, HS; Kim, IH; Kim, JH; Kim, JW; Lee, JI; Lee, JM; Lee, JW; Lee, SH; Park, SJ; Seo, YS; Suh, SJ; Yim, HJ | 1 |
| He, L; Jiang, Y; Liu, X; Wang, X; Yang, Z; Zhang, S; Zhao, Y | 1 |
9 review(s) available for 2'-fluorothymidine and guanine
| Article | Year |
|---|---|
[New management strategies for hepatitis B].
Topics: Adenine; Antiviral Agents; Arabinofuranosyluracil; Deoxycytidine; Emtricitabine; Guanine; Hepatitis B; Humans; Lamivudine; Organophosphonates | 2002 |
Entecavir, FTC, L-FMAU, LdT and others.
Topics: Antiviral Agents; Arabinofuranosyluracil; Clinical Trials as Topic; Deoxycytidine; Emtricitabine; Guanine; Hepatitis B, Chronic; Humans; Randomized Controlled Trials as Topic; Thymidine | 2003 |
Treatment of HBeAg negative chronic hepatitis B with new drugs (adefovir and others).
Topics: Adenine; Antiviral Agents; Arabinofuranosyluracil; Deoxycytidine; Emtricitabine; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Nucleosides; Organophosphonates | 2003 |
[New approaches in the treatment of hepatitis B].
Topics: 2-Aminopurine; Adenine; Antiviral Agents; Arabinofuranosyluracil; Carcinoma, Hepatocellular; Contraindications; Deoxycytidine; Emtricitabine; Famciclovir; Guanine; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Lamivudine; Liver Neoplasms; Organophosphonates; Organophosphorus Compounds; Polyethylene Glycols; Prodrugs; Prognosis; Recombinant Proteins; Tenofovir; Zalcitabine | 2004 |
New treatment of chronic hepatitis B.
Topics: Adenine; Animals; Antiviral Agents; Arabinofuranosyluracil; Deoxycytidine; Drug Resistance, Viral; Emtricitabine; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Organophosphonates; Organophosphorus Compounds; Pyrimidinones; Telbivudine; Tenofovir; Thymidine; Treatment Outcome | 2004 |
Drugs in development for hepatitis B.
Topics: Adenine; Antiviral Agents; Arabinofuranosyluracil; Deoxycytidine; Emtricitabine; Guanine; Hepatitis B; Humans; Interferon alpha-2; Interferon-alpha; Nucleosides; Organophosphonates; Polyethylene Glycols; Recombinant Proteins; Tenofovir | 2005 |
[Management of chronic hepatitis B in treatment-naive patients].
Topics: Adenine; Antiviral Agents; Arabinofuranosyluracil; Guanine; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Korea; Lamivudine; Organophosphonates; Polyethylene Glycols; Practice Guidelines as Topic; Recombinant Proteins | 2008 |
[Management of antiviral-resistant chronic hepatitis B virus infection].
Topics: Adenine; Antiviral Agents; Arabinofuranosyluracil; Drug Resistance, Multiple, Viral; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Mutation; Nucleosides; Organophosphonates; Practice Guidelines as Topic; Pyrimidinones; Telbivudine; Thymidine; Treatment Outcome | 2008 |
Efficacy of Nucleot(s)ide Analogs Therapy in Patients with Unresectable HBV-Related Hepatocellular Carcinoma: A Systematic Review and Meta-Analysis.
Topics: Adenine; Antiviral Agents; Arabinofuranosyluracil; Carcinoma, Hepatocellular; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Liver Neoplasms; Organophosphonates; Retrospective Studies; Survival Analysis; Telbivudine; Tenofovir; Thymidine | 2017 |
2 trial(s) available for 2'-fluorothymidine and guanine
| Article | Year |
|---|---|
[Treatment efficacy of clevudine, entecavir and lamivudine in treatment-naive patients with HBeAg-positive chronic hepatitis B].
Topics: Adult; Alanine Transaminase; Antiviral Agents; Arabinofuranosyluracil; DNA, Viral; Drug Administration Schedule; Drug Resistance, Viral; Female; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Retrospective Studies; Treatment Outcome | 2010 |
Structure-guided engineering of human thymidine kinase 2 as a positron emission tomography reporter gene for enhanced phosphorylation of non-natural thymidine analog reporter probe.
Topics: Adult; Animals; Arabinofuranosyluracil; Female; Fluorine Radioisotopes; Genes, Reporter; Guanine; Herpesvirus 1, Human; Humans; Male; Mice; Middle Aged; Models, Molecular; Phosphorylation; Positron-Emission Tomography; Protein Conformation; Protein Engineering; Thymidine; Thymidine Kinase | 2012 |
15 other study(ies) available for 2'-fluorothymidine and guanine
| Article | Year |
|---|---|
Sensitivity of L-(-)2,3-dideoxythiacytidine resistant hepatitis B virus to other antiviral nucleoside analogues.
Topics: Acyclovir; Adenine; Antiviral Agents; Arabinofuranosyluracil; DNA-Directed DNA Polymerase; Drug Resistance, Microbial; Drug Resistance, Multiple; Guanine; Hepatitis B virus; Lamivudine; Microbial Sensitivity Tests; Mutation; Nucleic Acid Synthesis Inhibitors; Organophosphonates; Zalcitabine | 1999 |
Direct comparison of radiolabeled probes FMAU, FHBG, and FHPG as PET imaging agents for HSV1-tk expression in a human breast cancer model.
Topics: Animals; Arabinofuranosyluracil; Breast Neoplasms; Carbon Radioisotopes; Diagnostic Imaging; Female; Ganciclovir; Gene Expression Regulation, Neoplastic; Gene Expression Regulation, Viral; Guanine; Herpesvirus 1, Human; Humans; Mice; Mice, Nude; Models, Biological; Neoplasm Transplantation; Positron-Emission Tomography; Radiopharmaceuticals; Thymidine Kinase; Time Factors; Tissue Distribution; Tumor Cells, Cultured | 2004 |
Comparison between clevudine and entecavir treatment for antiviral-naïve patients with chronic hepatitis B.
Topics: Adult; Alanine Transaminase; Antiviral Agents; Arabinofuranosyluracil; Biomarkers; DNA, Viral; Drug Resistance, Viral; Female; Genotype; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Muscular Diseases; Republic of Korea; Retrospective Studies; Time Factors; Treatment Outcome; Viral Load; Virus Replication | 2010 |
Evaluation of the in vitro anti-HBV activity of clevudine in combination with other nucleoside/nucleotide inhibitors.
Topics: Adenine; Anti-HIV Agents; Antiviral Agents; Arabinofuranosyluracil; Cell Line; Cells, Cultured; Drug Antagonism; Drug Synergism; Drug Therapy, Combination; Guanine; Hepatitis B virus; Hepatocytes; Humans; Lamivudine; Microbial Sensitivity Tests; Nucleosides; Nucleotides; Organophosphonates; Pyrimidinones; Reverse Transcriptase Inhibitors; Telbivudine; Tenofovir; Thymidine | 2010 |
Experience of anti-viral therapy in hepatitis B-associated membranous nephropathy, including Lamivudine-resistant strains.
Topics: Adenine; Adult; Antiviral Agents; Arabinofuranosyluracil; Drug Resistance, Viral; Female; Glomerulonephritis, Membranous; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Young Adult | 2012 |
Long-term treatment outcomes of clevudine in antiviral-naive patients with chronic hepatitis B.
Topics: Adult; Alanine Transaminase; Antiviral Agents; Arabinofuranosyluracil; DNA, Viral; Female; Genotype; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Middle Aged; Mutation; Retrospective Studies; Treatment Outcome | 2012 |
[Efficacy of entecavir switching therapy in chronic hepatitis B patients with clevudine-induced myopathy].
Topics: Adult; Aged; Alanine Transaminase; Antiviral Agents; Arabinofuranosyluracil; Creatine Kinase; DNA, Viral; Drug Resistance, Viral; Female; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Middle Aged; Muscular Diseases | 2013 |
[Antiviral effect of entecavir switching therapy in chronic hepatitis B patients with clevudine-associated myopathy].
Topics: Antiviral Agents; Arabinofuranosyluracil; Female; Guanine; Hepatitis B, Chronic; Humans; Male; Muscular Diseases | 2013 |
Noncompetitive inhibition of hepatitis B virus reverse transcriptase protein priming and DNA synthesis by the nucleoside analog clevudine.
Topics: Adenine; Arabinofuranosyluracil; DNA, Viral; Guanine; HEK293 Cells; Hepatitis B virus; Humans; Organophosphonates; Protein Binding; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Tenofovir; Viral Proteins | 2013 |
Patients with chronic hepatitis B treated with oral antiviral therapy retain a higher risk for HCC compared with patients with inactive stage disease.
Topics: Adult; Antiviral Agents; Arabinofuranosyluracil; Carcinoma, Hepatocellular; Female; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Incidence; Kaplan-Meier Estimate; Lamivudine; Liver; Liver Cirrhosis; Liver Neoplasms; Male; Middle Aged; Outcome Assessment, Health Care; Patient Acuity; Republic of Korea; Retrospective Studies; Risk Assessment; Risk Factors; Time | 2014 |
Oral antiviral therapy improves the diagnostic accuracy of alpha-fetoprotein levels in patients with chronic hepatitis B.
Topics: Administration, Oral; Adult; Aged; alpha-Fetoproteins; Antiviral Agents; Arabinofuranosyluracil; Biomarkers; Carcinoma, Hepatocellular; Female; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Liver Neoplasms; Male; Middle Aged; Predictive Value of Tests; Retrospective Studies; Sensitivity and Specificity; Time Factors | 2014 |
Antiviral therapy of chronic hepatitis B.
Topics: Adenine; Antiviral Agents; Arabinofuranosyluracil; Carcinoma, Hepatocellular; Gene Products, pol; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Liver; Liver Cirrhosis; Liver Neoplasms; Organophosphonates; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Telbivudine; Tenofovir; Thymidine; Treatment Outcome; Virus Replication | 2014 |
Off-treatment virologic relapse and outcomes of re-treatment in chronic hepatitis B patients who achieved complete viral suppression with oral nucleos(t)ide analogs.
Topics: Adult; Aged; Antiviral Agents; Arabinofuranosyluracil; Drug Resistance, Viral; Female; Genotype; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Multivariate Analysis; Recurrence; Retrospective Studies; Treatment Outcome | 2014 |
Substitution at rt269 in Hepatitis B Virus Polymerase Is a Compensatory Mutation Associated with Multi-Drug Resistance.
Topics: Adenine; Amino Acid Substitution; Antiviral Agents; Arabinofuranosyluracil; Cell Line, Tumor; Drug Resistance, Multiple, Viral; Gene Products, pol; Guanine; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Microbial Sensitivity Tests; Models, Molecular; Organophosphonates; Tenofovir; Virus Replication | 2015 |
Management of Clevudine-Resistant Chronic Hepatitis B: A Multicenter Cohort Study.
Topics: Adenine; Adult; Aged; Antiviral Agents; Arabinofuranosyluracil; Cohort Studies; Disease Management; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Female; Genotype; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Viral Load | 2017 |