Page last updated: 2024-09-04

2'-fluorothymidine and 9-(4-fluoro-3-hydroxymethylbutyl)guanine

2'-fluorothymidine has been researched along with 9-(4-fluoro-3-hydroxymethylbutyl)guanine in 2 studies

Compound Research Comparison

Studies (2'-fluorothymidine)	Trials (2'-fluorothymidine)	Recent Studies (post-2010) (2'-fluorothymidine)	Studies (9-(4-fluoro-3-hydroxymethylbutyl)guanine)	Trials (9-(4-fluoro-3-hydroxymethylbutyl)guanine)	Recent Studies (post-2010) (9-(4-fluoro-3-hydroxymethylbutyl)guanine)
187	18	39	49	3	7

Protein Interaction Comparison

Protein	Taxonomy	2'-fluorothymidine (IC50)	9-(4-fluoro-3-hydroxymethylbutyl)guanine (IC50)
Thymidine kinase	Human alphaherpesvirus 1 (Herpes simplex virus type 1)		9

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (50.00)	29.6817
2010's	1 (50.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Alauddin, MM; Conti, PS; Gordon, EM; Shahinian, A	1
Auerbach, MS; Campbell, DO; Czernin, J; Herschman, H; Lavie, A; Lee, JT; Radu, CG; Satyamurthy, N; Su, Y; Yaghoubi, SS	1

Trials

1 trial(s) available for 2'-fluorothymidine and 9-(4-fluoro-3-hydroxymethylbutyl)guanine

Article	Year
Structure-guided engineering of human thymidine kinase 2 as a positron emission tomography reporter gene for enhanced phosphorylation of non-natural thymidine analog reporter probe. The Journal of biological chemistry, 2012, Jan-02, Volume: 287, Issue:1 Topics: Adult; Animals; Arabinofuranosyluracil; Female; Fluorine Radioisotopes; Genes, Reporter; Guanine; Herpesvirus 1, Human; Humans; Male; Mice; Middle Aged; Models, Molecular; Phosphorylation; Positron-Emission Tomography; Protein Conformation; Protein Engineering; Thymidine; Thymidine Kinase	2012

Article

Year

Structure-guided engineering of human thymidine kinase 2 as a positron emission tomography reporter gene for enhanced phosphorylation of non-natural thymidine analog reporter probe.

The Journal of biological chemistry, 2012, Jan-02, Volume: 287, Issue:1

Topics: Adult; Animals; Arabinofuranosyluracil; Female; Fluorine Radioisotopes; Genes, Reporter; Guanine; Herpesvirus 1, Human; Humans; Male; Mice; Middle Aged; Models, Molecular; Phosphorylation; Positron-Emission Tomography; Protein Conformation; Protein Engineering; Thymidine; Thymidine Kinase

2012

Other Studies

1 other study(ies) available for 2'-fluorothymidine and 9-(4-fluoro-3-hydroxymethylbutyl)guanine

Article	Year
Direct comparison of radiolabeled probes FMAU, FHBG, and FHPG as PET imaging agents for HSV1-tk expression in a human breast cancer model. Molecular imaging, 2004, Volume: 3, Issue:2 Topics: Animals; Arabinofuranosyluracil; Breast Neoplasms; Carbon Radioisotopes; Diagnostic Imaging; Female; Ganciclovir; Gene Expression Regulation, Neoplastic; Gene Expression Regulation, Viral; Guanine; Herpesvirus 1, Human; Humans; Mice; Mice, Nude; Models, Biological; Neoplasm Transplantation; Positron-Emission Tomography; Radiopharmaceuticals; Thymidine Kinase; Time Factors; Tissue Distribution; Tumor Cells, Cultured	2004

Article

Year

Direct comparison of radiolabeled probes FMAU, FHBG, and FHPG as PET imaging agents for HSV1-tk expression in a human breast cancer model.

Molecular imaging, 2004, Volume: 3, Issue:2

Topics: Animals; Arabinofuranosyluracil; Breast Neoplasms; Carbon Radioisotopes; Diagnostic Imaging; Female; Ganciclovir; Gene Expression Regulation, Neoplastic; Gene Expression Regulation, Viral; Guanine; Herpesvirus 1, Human; Humans; Mice; Mice, Nude; Models, Biological; Neoplasm Transplantation; Positron-Emission Tomography; Radiopharmaceuticals; Thymidine Kinase; Time Factors; Tissue Distribution; Tumor Cells, Cultured

2004