2'-fluoro-2'-deoxycytidine has been researched along with deoxycytidine in 19 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (15.79) | 18.7374 |
| 1990's | 1 (5.26) | 18.2507 |
| 2000's | 6 (31.58) | 29.6817 |
| 2010's | 5 (26.32) | 24.3611 |
| 2020's | 4 (21.05) | 2.80 |
| Authors | Studies |
|---|---|
| Bao, H; Furman, PA; McBrayer, TR; Micolochick Steuer, HM; Murakami, E; Obikhod, A; Otto, MJ; Ramesh, M; Schinazi, RF; Stuyver, LJ; Whitaker, T | 1 |
| Bao, H; Furman, PA; Micolochick Steuer, HM; Murakami, E; Nachman, T; Niu, C; Otto, MJ; Sofia, MA; Wang, P; Whitaker, T | 1 |
| Cech, D; Krynetskaya, NF; Metelev, VG; Niemann, A; Oretskaya, TS; Schmidt, S; Shabarova, ZA; Suchomlinov, VV | 1 |
| Aoyama, H; Guschlbauer, W; Litvak, S; Sarih-Cottin, L; Tarrago-Litvak, L | 1 |
| Guschlbauer, W; Hay, J; Jamieson, AT; Mengel, R; Wohlrab, F | 1 |
| Brox, LW; Hendler, SS; LePage, GA; Shannahoff, DH | 1 |
| Bendele, RA; Koc, H; Lehrman, SR; Richardson, FC; Richardson, KA; Swenberg, JA; Zhang, C | 1 |
| Cartee, L; Hobbs, A; Lostia, S; McBrayer, TR; Otto, MJ; Ramesh, M; Schinazi, RF; Shi, J; Stuyver, LJ; Tharnish, PM; Watanabe, KA; Whitaker, T | 1 |
| Bajramovic, JJ; Gonzalez-Dunia, D; Pochet, S; Syan, S; Volmer, R | 1 |
| Beijnen, JH; Jansen, RS; Rosing, H; Schellens, JH | 1 |
| Barnard, DL; Day, CW; Kumaki, Y; Morrey, JD; Smee, DF | 1 |
| Albariño, CG; Bluemling, GR; Chakrabarti, AK; Flint, M; Guerrero, LW; McMullan, LK; Nichol, ST; Painter, GR; Spiropoulou, CF; Welch, SR | 1 |
| Guo, X; Ingale, SA; Leonard, P; Seela, F | 1 |
| Bergeron, É; Chatterjee, P; Flint, M; Nichol, ST; Scholte, FEM; Spiropoulou, CF; Welch, SR | 1 |
| Gowen, BB; Jung, KH; Smee, DF; Westover, J | 1 |
| Amblard, F; Bassit, L; Chatterjee, P; Flint, M; Kasthuri, M; Li, C; Lo, MK; Nichol, ST; Russell, O; Schinazi, RF; Spiropoulou, CF; Verma, K | 1 |
| Li, Y; Miao, Z; Pan, Q; Peppelenbosch, MP; Wang, Y; Yu, P | 1 |
| An, T; Jang, Y; Jung, E; Kim, K; Kim, M; Kim, UI; Lee, MK; Shin, JS | 1 |
| Chvátil, D; Kočišek, J; Lyshchuk, H; Šáchová, J; Sala, L | 1 |
19 other study(ies) available for 2'-fluoro-2'-deoxycytidine and deoxycytidine
| Article | Year |
|---|---|
Mechanism of activation of beta-D-2'-deoxy-2'-fluoro-2'-c-methylcytidine and inhibition of hepatitis C virus NS5B RNA polymerase.
Topics: Antiviral Agents; Catalysis; Deoxycytidine; Hepacivirus; Hepatitis C; Humans; Mutation; Phosphorylation; RNA-Dependent RNA Polymerase; RNA, Viral; Structure-Activity Relationship; Viral Nonstructural Proteins; Virus Replication | 2007 |
The mechanism of action of beta-D-2'-deoxy-2'-fluoro-2'-C-methylcytidine involves a second metabolic pathway leading to beta-D-2'-deoxy-2'-fluoro-2'-C-methyluridine 5'-triphosphate, a potent inhibitor of the hepatitis C virus RNA-dependent RNA polymerase.
Topics: Antiviral Agents; Cell Line; Cytidine; Deoxycytidine; Hepacivirus; Humans; Microbial Sensitivity Tests; Phosphorylation; Replicon; RNA-Dependent RNA Polymerase; Structure-Activity Relationship; Uridine Triphosphate | 2008 |
The use of oligonucleotide probes containing 2'-deoxy-2'-fluoronucleosides for regiospecific cleavage of RNA by RNase H from Escherichia coli.
Topics: Base Sequence; Deoxycytidine; Escherichia coli; Floxuridine; Molecular Sequence Data; Nucleic Acid Conformation; Oligonucleotide Probes; Ribonuclease H; RNA, Bacterial; RNA, Ribosomal, 5S; RNA, Transfer, Phe | 1992 |
2'-Fluoro-2'-deoxycytidine triphosphate as a substrate for RNA- and DNA-dependent DNA polymerases.
Topics: Animals; Aphidicolin; Avian Myeloblastosis Virus; Deoxycytidine; Diterpenes; DNA Polymerase II; DNA Polymerase III; DNA Replication; DNA-Directed DNA Polymerase; Female; Magnesium; Manganese; Mice; Oocytes; RNA-Directed DNA Polymerase; Xenopus laevis | 1985 |
The effect of 2'-fluoro-2'-deoxycytidine on herpes virus growth.
Topics: Animals; Cell Division; Cricetinae; Cytarabine; Cytidine; Deoxycytidine; Herpesvirus 1, Equid; Herpesvirus 1, Suid; Humans; Phosphorylation; Simplexvirus; Thymidine Kinase | 1985 |
Studies on the growth inhibition and metabolism of 2'-deoxy-2'-fluorocytidine in cultured human lymphoblasts.
Topics: Carbon Radioisotopes; Cell Division; Cell Line; Cells, Cultured; Cytidine; Deoxycytidine; Deoxyribonucleosides; DNA, Neoplasm; Fluorine; Humans; Leukemia, Lymphoid; Tritium | 1974 |
Quantification of 2'-fluoro-2'-deoxyuridine and 2'-fluoro-2'-deoxycytidine in DNA and RNA isolated from rats and woodchucks using LC/MS/MS.
Topics: Animals; Chromatography, High Pressure Liquid; Deoxycytidine; DNA; Floxuridine; Hydrolysis; Male; Marmota; Organ Specificity; Rats; Rats, Inbred F344; RNA; Spectrometry, Mass, Electrospray Ionization | 2002 |
Inhibition of the subgenomic hepatitis C virus replicon in huh-7 cells by 2'-deoxy-2'-fluorocytidine.
Topics: Animals; Antiviral Agents; Cattle; Cell Division; Cell Line; Deoxycytidine; Diarrhea Viruses, Bovine Viral; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hepacivirus; Humans; Replicon; RNA, Viral; S Phase; Viral Nonstructural Proteins | 2004 |
2'-fluoro-2'-deoxycytidine inhibits Borna disease virus replication and spread.
Topics: Animals; Antiviral Agents; Borna Disease; Borna disease virus; Chlorocebus aethiops; Cytarabine; Deoxycytidine; RNA, Viral; Vero Cells; Virus Replication | 2004 |
Simultaneous quantification of 2',2'-difluorodeoxycytidine and 2',2'-difluorodeoxyuridine nucleosides and nucleotides in white blood cells using porous graphitic carbon chromatography coupled with tandem mass spectrometry.
Topics: Antimetabolites, Antineoplastic; Chromatography; Deoxycytidine; Gemcitabine; Humans; Leukocytes; Nucleosides; Nucleotides; Tandem Mass Spectrometry | 2009 |
In vitro and in vivo efficacy of fluorodeoxycytidine analogs against highly pathogenic avian influenza H5N1, seasonal, and pandemic H1N1 virus infections.
Topics: Animals; Antiviral Agents; Cell Line; Deoxycytidine; Dogs; Female; Histocytochemistry; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza A Virus, H5N1 Subtype; Injections, Intraperitoneal; Lung; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Orthomyxoviridae Infections; Survival Analysis; Viral Load | 2011 |
Lassa and Ebola virus inhibitors identified using minigenome and recombinant virus reporter systems.
Topics: Antiviral Agents; Azauridine; Deoxycytidine; Drug Discovery; Ebolavirus; Genes, Reporter; Genome, Viral; Green Fluorescent Proteins; Hemorrhagic Fever, Ebola; High-Throughput Screening Assays; Humans; Lassa Fever; Lassa virus; Luciferases | 2016 |
Gemcitabine, Pyrrologemcitabine, and 2'-Fluoro-2'-Deoxycytidines: Synthesis, Physical Properties, and Impact of Sugar Fluorination on Silver Ion Mediated Base Pairing.
Topics: Base Pairing; Deoxycytidine; Gemcitabine; Halogenation; Ions; Magnetic Resonance Spectroscopy; Oligonucleotides; Ribose; Silver; Spectrometry, Fluorescence | 2017 |
Identification of 2'-deoxy-2'-fluorocytidine as a potent inhibitor of Crimean-Congo hemorrhagic fever virus replication using a recombinant fluorescent reporter virus.
Topics: Amides; Antiviral Agents; Cell Line, Tumor; Cell Survival; Deoxycytidine; Dose-Response Relationship, Drug; Drug Discovery; Drug Synergism; Genes, Reporter; Green Fluorescent Proteins; Hemorrhagic Fever Virus, Crimean-Congo; Hemorrhagic Fever, Crimean; High-Throughput Screening Assays; Humans; Lethal Dose 50; Pyrazines; Ribavirin; Viral Proteins; Virus Replication | 2017 |
2'-Fluoro-2'-deoxycytidine is a broad-spectrum inhibitor of bunyaviruses in vitro and in phleboviral disease mouse models.
Topics: Animal Structures; Animals; Antiviral Agents; Body Weight; Bunyaviridae Infections; Cytopathogenic Effect, Viral; Deoxycytidine; Disease Models, Animal; DNA Viruses; Mice; Microbial Sensitivity Tests; Placebos; RNA Viruses; Survival Analysis; Treatment Outcome; Viral Load | 2018 |
Potent in vitro activity of β-D-4'-chloromethyl-2'-deoxy-2'-fluorocytidine against Nipah virus.
Topics: Antiviral Agents; Cell Line; Cell Survival; Deoxycytidine; Epithelial Cells; HeLa Cells; Humans; Lung; Nipah Virus; Nucleosides; Paramyxoviridae | 2020 |
2'-Fluoro-2'-deoxycytidine inhibits murine norovirus replication and synergizes MPA, ribavirin and T705.
Topics: Amides; Animals; Antiviral Agents; Caliciviridae Infections; Cell Line; Deoxycytidine; Humans; Mice; Mycophenolic Acid; Norovirus; Pyrazines; RAW 264.7 Cells; Ribavirin; Virus Replication | 2020 |
Comparison of Antiviral Activity of Gemcitabine with 2'-Fluoro-2'-Deoxycytidine and Combination Therapy with Remdesivir against SARS-CoV-2.
Topics: Adenosine Monophosphate; Alanine; Animals; Antiviral Agents; Cell Line; Chlorocebus aethiops; COVID-19; COVID-19 Drug Treatment; Deoxycytidine; Drug Therapy, Combination; Gemcitabine; Humans; Inhibitory Concentration 50; SARS-CoV-2; Vero Cells; Virus Replication | 2021 |
Different Mechanisms of DNA Radiosensitization by 8-Bromoadenosine and 2'-Deoxy-2'-fluorocytidine Observed on DNA Origami Nanoframe Supports.
Topics: Adenosine; Deoxycytidine; DNA; DNA Damage; DNA Repair | 2022 |