2'-fluoro-2'-deoxycytidine has been researched along with 2'-c-methylcytidine in 4 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bao, H; Furman, PA; McBrayer, TR; Micolochick Steuer, HM; Murakami, E; Obikhod, A; Otto, MJ; Ramesh, M; Schinazi, RF; Stuyver, LJ; Whitaker, T | 1 |
| Baker, SJ; Blomgren, PA; Cammack, N; Devos, R; Granycome, C; Hang, J; Hobbs, CJ; Jiang, WR; Klumpp, K; Laxton, C; Le Pogam, S; Leveque, V; Ma, H; Maile, G; Martin, JA; Merrett, JH; Najera, I; Pichota, A; Sarma, K; Smith, DB; Smith, M; Swallow, S; Symons, J; Vesey, D | 1 |
| Bao, H; Furman, PA; Micolochick Steuer, HM; Murakami, E; Nachman, T; Niu, C; Otto, MJ; Sofia, MA; Wang, P; Whitaker, T | 1 |
| Haverkamp, C; Liu, C; Schneller, SW | 1 |
4 other study(ies) available for 2'-fluoro-2'-deoxycytidine and 2'-c-methylcytidine
| Article | Year |
|---|---|
Mechanism of activation of beta-D-2'-deoxy-2'-fluoro-2'-c-methylcytidine and inhibition of hepatitis C virus NS5B RNA polymerase.
Topics: Antiviral Agents; Catalysis; Deoxycytidine; Hepacivirus; Hepatitis C; Humans; Mutation; Phosphorylation; RNA-Dependent RNA Polymerase; RNA, Viral; Structure-Activity Relationship; Viral Nonstructural Proteins; Virus Replication | 2007 |
Design, synthesis, and antiviral properties of 4'-substituted ribonucleosides as inhibitors of hepatitis C virus replication: the discovery of R1479.
Topics: Antiviral Agents; Chemistry, Pharmaceutical; Cytidine; Drug Design; Drug Evaluation, Preclinical; Hepacivirus; Inhibitory Concentration 50; Models, Chemical; Molecular Conformation; Nucleosides; Ribonucleosides; RNA; Uridine; Virus Replication | 2007 |
The mechanism of action of beta-D-2'-deoxy-2'-fluoro-2'-C-methylcytidine involves a second metabolic pathway leading to beta-D-2'-deoxy-2'-fluoro-2'-C-methyluridine 5'-triphosphate, a potent inhibitor of the hepatitis C virus RNA-dependent RNA polymerase.
Topics: Antiviral Agents; Cell Line; Cytidine; Deoxycytidine; Hepacivirus; Humans; Microbial Sensitivity Tests; Phosphorylation; Replicon; RNA-Dependent RNA Polymerase; Structure-Activity Relationship; Uridine Triphosphate | 2008 |
Enantiomeric 4'-truncated 6'-fluoro-3-deazaneplanocin and its 3-bromo derivative: Synthesis and antiviral properties, including Ebola and Marburg.
Topics: Adenosine; Antiviral Agents; Dose-Response Relationship, Drug; Ebolavirus; Marburgvirus; Molecular Structure; Stereoisomerism; Structure-Activity Relationship | 2021 |