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2'-deoxyuridylic acid and thymidine monophosphate

2'-deoxyuridylic acid has been researched along with thymidine monophosphate in 37 studies

Research

Studies (37)

Timeframe	Studies, this research(%)	All Research%
pre-1990	9 (24.32)	18.7374
1990's	11 (29.73)	18.2507
2000's	14 (37.84)	29.6817
2010's	3 (8.11)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Hansch, C; Santi, DV; Wataya, Y	1
Garvey, EP; Goldstein, S; Pogolotti, AL; Santi, DV	1
Hall, ET; Kuchta, RD; Melançon, P; Miller, WH; Traynor, AJ; Walker, G	1
Herdewijn, P; Munier-Lehmann, H; Pochet, S; Van Calenbergh, S; Vanheusden, V	1
Herdewijn, P; Munier-Lehmann, H; Pochet, S; Van Calenbergh, S; Van Rompaey, P; Vanheusden, V	1
Agrofoglio, LA; Alexandre, JA; Andrei, G; Azzouzi, A; Balzarini, J; Broggi, J; Caillat, C; Deville-Bonne, D; El-Amri, C; Eriksson, S; Lin, J; Meyer, P; Pradère, U; Roy, V; Snoeck, R; Topalis, D	1
Carreras, CW; Climie, SC; Santi, DV	1
Kondo, T; Krishna, CM; Riesz, P	1
Mittelstaedt, DM; Schimerlik, MI	1
Bianchi, V; Pontis, E; Reichard, P	1
Rode, W	1
Garvey, EP; Santi, DV	1
Ahmed, F; Dunlap, RB; Moore, MA	1
Aull, JL; Daron, HH; Ivery, TC	1
Laszlo, J; Richards, RG; Sedwick, WD; Sowers, LC	1
Connick, TJ; Dunlap, RB; Ellis, PD; Reilly, RT	1
Appley, MI; Aull, JL; Daron, HH	1
Nyce, GW; White, RH	1
Clifton, IJ; Davisson, VJ; Santi, DV; Schiffer, CA; Stroud, RM	1
Appleman, JR; Spencer, HT; Villafranca, JE	1
Chiericatti, G; Santi, DV	1
Copp, AJ; Fleming, A	1
Berger, SH; Dunlap, RB; Spencer, HT; Steadman, DJ	1
Lee, TT; Liu, Y; Santi, DV; Stroud, RM; Variath, P	1
Bianchi, V; Frigimelica, E; Gallinaro, L; Milanesi, E; Rampazzo, C; Reichard, P	1
Arora, PS; Eisenführ, A; Famulok, M; Nowick, JS; Sengle, G	1
Filee, J; Forterre, P; Leduc, D; Liebl, U; Lipowski, G; Myllykallio, H	1
Murzin, AG	1
Graziani, S; Gurnon, JR; Leduc, D; Liebl, U; Myllykallio, H; Skouloubris, S; Van Etten, JL; Xia, Y	1
Griffin, J; Iliffe-Lee, E; McClarty, G; Roshick, C	1
Gattis, SG; Palfey, BA	1
Changchien, L; Maley, F; Montfort, WR; Sotelo-Mundo, RR	1
Costi, MP; Ferrari, S	1
Conrad, JA; Fleischmann, T; Koehn, EM; Kohen, A; Lesley, SA; Mathews, II; Palfey, BA	1
Carli, D; Cohen, S; Dumontet, C; Guitton, J; Honorat, M; Megherbi, M; Payen, L; Vignal, B	1
Kohen, A; Saeed, M; Sheff, D	1
Dong, Y; Guan, Z; Niu, B; Wang, J; Wang, X; Xu, L; Zhang, J; Zhang, T	1

Reviews

1 review(s) available for 2'-deoxyuridylic acid and thymidine monophosphate

Article	Year
[Thymidylate biosynthesis: its biological role and regulation in animal cells]. Postepy biochemii, 1986, Volume: 32, Issue:4 Topics: Animals; Deoxyuracil Nucleotides; Homeostasis; Humans; Oxidative Phosphorylation; Thymidine; Thymidine Monophosphate; Thymidylate Synthase; Thymine Nucleotides	1986

Other Studies

36 other study(ies) available for 2'-deoxyuridylic acid and thymidine monophosphate

Article	Year
Inhibition of Lactobacillus casei thymidylate synthetase by 5-substituted 2'-deoxyuridylates. Preliminary quantitative structure-activity relationship. Journal of medicinal chemistry, 1977, Volume: 20, Issue:11 Topics: Deoxyuracil Nucleotides; Kinetics; Lacticaseibacillus casei; Methyltransferases; Structure-Activity Relationship; Thymidylate Synthase	1977
Interaction of N4-hydroxy-2'-deoxycytidylic acid with thymidylate synthetase. Journal of medicinal chemistry, 1984, Volume: 27, Issue:10 Topics: Carbon Radioisotopes; Deoxycytidine Monophosphate; Deoxycytosine Nucleotides; Isotope Labeling; Kinetics; Lacticaseibacillus casei; Methyltransferases; Protein Binding; Thymidylate Synthase	1984
Inhibition of UDP-N-acetylglucosamine import into Golgi membranes by nucleoside monophosphates. Journal of medicinal chemistry, 1996, Jul-19, Volume: 39, Issue:15 Topics: Animals; Binding, Competitive; Biological Transport; Carrier Proteins; Glycosylation; Golgi Apparatus; Intracellular Membranes; Kinetics; Liver; Nucleotides; Phosphates; Rabbits; Ribose; Structure-Activity Relationship; Uridine Diphosphate N-Acetylglucosamine; Uridine Diphosphate Sugars	1996
Synthesis and evaluation of thymidine-5'-O-monophosphate analogues as inhibitors of Mycobacterium tuberculosis thymidylate kinase. Bioorganic & medicinal chemistry letters, 2002, Oct-07, Volume: 12, Issue:19 Topics: Antitubercular Agents; Crystallography, X-Ray; Enzyme Inhibitors; Kinetics; Models, Molecular; Mycobacterium tuberculosis; Nucleoside-Phosphate Kinase; Thymidine Monophosphate	2002
Thymidine and thymidine-5'-O-monophosphate analogues as inhibitors of Mycobacterium tuberculosis thymidylate kinase. Bioorganic & medicinal chemistry letters, 2003, Sep-15, Volume: 13, Issue:18 Topics: Antitubercular Agents; Enzyme Inhibitors; Inhibitory Concentration 50; Kinetics; Mycobacterium tuberculosis; Nucleoside-Phosphate Kinase; Structure-Activity Relationship; Thymidine; Thymine Nucleotides	2003
Novel antiviral C5-substituted pyrimidine acyclic nucleoside phosphonates selected as human thymidylate kinase substrates. Journal of medicinal chemistry, 2011, Jan-13, Volume: 54, Issue:1 Topics: Antiviral Agents; Catalytic Domain; Cells, Cultured; Crystallography, X-Ray; Herpesviridae; Humans; Ligands; Models, Molecular; Molecular Structure; Nucleoside-Phosphate Kinase; Organophosphonates; Prodrugs; Pyrimidine Nucleosides; Stereoisomerism; Structure-Activity Relationship; Substrate Specificity; Thymidine; Thymidine Kinase	2011
Thymidylate synthase with a C-terminal deletion catalyzes partial reactions but is unable to catalyze thymidylate formation. Biochemistry, 1992, Jul-07, Volume: 31, Issue:26 Topics: Catalysis; Deoxyuracil Nucleotides; Escherichia coli; Idoxuridine; Lacticaseibacillus casei; Mutagenesis; Structure-Activity Relationship; Sulfhydryl Compounds; Tetrahydrofolates; Thymidine Monophosphate; Thymidylate Synthase	1992
Pyrolysis radicals formed by ultrasound in aqueous solutions of nucleotides: a spin trapping study. International journal of radiation biology, 1990, Volume: 57, Issue:1 Topics: Cytidine Monophosphate; Deoxyribose; Deoxyuracil Nucleotides; Free Radicals; Hot Temperature; Nucleotides; Ribose; Solutions; Thymidine Monophosphate; Ultrasonics; Uridine Monophosphate; Water	1990
Stopped-flow studies of 2'-deoxynucleotide binding to thymidylate synthase. Archives of biochemistry and biophysics, 1986, Volume: 245, Issue:2 Topics: Binding Sites; Deoxyribonucleotides; Deoxyuracil Nucleotides; Fluorodeoxyuridylate; Kinetics; Lacticaseibacillus casei; Mathematics; Models, Chemical; Protein Binding; Protein Conformation; Spectrometry, Fluorescence; Thermodynamics; Thymidine Monophosphate; Thymidylate Synthase	1986
Interrelations between substrate cycles and de novo synthesis of pyrimidine deoxyribonucleoside triphosphates in 3T6 cells. Proceedings of the National Academy of Sciences of the United States of America, 1986, Volume: 83, Issue:4 Topics: Animals; Cell Cycle; Cell Line; Deoxycytosine Nucleotides; Deoxyribonucleosides; Deoxyuracil Nucleotides; Dipyridamole; DNA Replication; Fibroblasts; Hydroxyurea; Mice; Phosphorylation; Thymidine Monophosphate; Thymine Nucleotides	1986
A stable binary complex between Leishmania major thymidylate synthase and the substrate deoxyuridylate. A slow-binding interaction. The Journal of biological chemistry, 1987, Jul-05, Volume: 262, Issue:19 Topics: Animals; Binding, Competitive; Deoxyuracil Nucleotides; Fluorodeoxyuridylate; Folic Acid; Kinetics; Leishmania tropica; Quinazolines; Thymidine Monophosphate; Thymidylate Synthase	1987
Evidence for the existence of covalent nucleotide-thymidylate synthase complexes, identification of site of attachment, and enhancement by folates. The Journal of biological chemistry, 1986, Sep-25, Volume: 261, Issue:27 Topics: Deoxyuracil Nucleotides; Fluorodeoxyuridylate; Folic Acid; Tetrahydrofolates; Thymidine Monophosphate; Thymidylate Synthase	1986
The inactivation of thymidylate synthase by periodate. Journal of inorganic biochemistry, 1984, Volume: 22, Issue:4 Topics: Deoxyuracil Nucleotides; Lacticaseibacillus casei; Methyltransferases; Periodic Acid; Sulfhydryl Compounds; Thymidine Monophosphate; Thymidylate Synthase	1984
The occurrence and consequences of deoxyuridine in DNA. Advances in enzyme regulation, 1984, Volume: 22 Topics: Base Composition; Centrifugation, Density Gradient; Chromatin; Cytosine; Deamination; Deoxyribonuclease IV (Phage T4-Induced); Deoxyuracil Nucleotides; Deoxyuridine; DNA; DNA Glycosylases; DNA-(Apurinic or Apyrimidinic Site) Lyase; Endodeoxyribonucleases; Folic Acid Antagonists; Humans; Models, Chemical; N-Glycosyl Hydrolases; Protons; Pyrophosphatases; Thymidine Monophosphate; Uracil-DNA Glycosidase	1984
Phosphorus-31 nuclear magnetic resonance studies of complexes of thymidylate synthase. Biochimica et biophysica acta, 1994, Sep-21, Volume: 1208, Issue:1 Topics: Deoxyuracil Nucleotides; Fluorodeoxyuridylate; Folic Acid; Magnetic Resonance Spectroscopy; Phosphorus Isotopes; Quinazolines; Tetrahydrofolates; Thymidine Monophosphate; Thymidylate Synthase	1994
Interaction of pyridoxal phosphate with thymidylate synthase: spectral and equilibrium dialysis studies. The International journal of biochemistry, 1993, Volume: 25, Issue:5 Topics: Binding Sites; Deoxyuracil Nucleotides; Dialysis; Fluorodeoxyuridylate; Pyridoxal Phosphate; Spectrophotometry, Ultraviolet; Thymidine Monophosphate; Thymidylate Synthase	1993
dTMP biosynthesis in Archaea. Journal of bacteriology, 1996, Volume: 178, Issue:3 Topics: Deoxyuracil Nucleotides; Methanosarcina; Sulfolobus; Thymidine Monophosphate	1996
Crystal structure of human thymidylate synthase: a structural mechanism for guiding substrates into the active site. Biochemistry, 1995, Dec-19, Volume: 34, Issue:50 Topics: Amino Acid Sequence; Binding Sites; Conserved Sequence; Crystallography; Deoxyuracil Nucleotides; DNA Transposable Elements; Eukaryotic Cells; Humans; Hydrogen Bonding; Models, Molecular; Molecular Sequence Data; Protein Structure, Tertiary; Sequence Alignment; Structure-Activity Relationship; Synchrotrons; Thymidine Monophosphate; Thymidylate Synthase	1995
Kinetic scheme for thymidylate synthase from Escherichia coli: determination from measurements of ligand binding, primary and secondary isotope effects, and pre-steady-state catalysis. Biochemistry, 1997, Apr-08, Volume: 36, Issue:14 Topics: Catalysis; Deoxyuracil Nucleotides; Escherichia coli; Folic Acid; Folic Acid Antagonists; Kinetics; Ligands; Molecular Structure; Mutagenesis, Site-Directed; Protein Binding; Protein Conformation; Quinazolines; Spectrometry, Fluorescence; Spectrophotometry; Tetrahydrofolates; Thermodynamics; Thymidine Monophosphate; Thymidylate Synthase	1997
Aspartate 221 of thymidylate synthase is involved in folate cofactor binding and in catalysis. Biochemistry, 1998, Jun-23, Volume: 37, Issue:25 Topics: Aspartic Acid; Binding Sites; Catalysis; Coenzymes; Deoxyuracil Nucleotides; Escherichia coli; Fluorodeoxyuridylate; Genetic Complementation Test; Halogens; Kinetics; Lacticaseibacillus casei; Mutagenesis, Insertional; Tetrahydrofolates; Thymidine Monophosphate; Thymidylate Synthase	1998
Embryonic folate metabolism and mouse neural tube defects. Science (New York, N.Y.), 1998, Jun-26, Volume: 280, Issue:5372 Topics: Animals; Central Nervous System; Deoxyuracil Nucleotides; DNA-Binding Proteins; Embryo, Mammalian; Female; Folic Acid; Humans; Male; Methionine; Mice; Mice, Inbred CBA; Mutation; Neural Tube Defects; Paired Box Transcription Factors; PAX3 Transcription Factor; Pyrimidines; Tetrahydrofolates; Thymidine; Thymidine Monophosphate; Transcription Factors	1998
Substitution at residue 214 of human thymidylate synthase alters nucleotide binding and isomerization of ligand-protein complexes. Biochemistry, 1999, Apr-27, Volume: 38, Issue:17 Topics: Amino Acid Substitution; Binding Sites; Deoxyuracil Nucleotides; Enzyme Activation; Glutamine; Humans; Isoenzymes; Kinetics; Ligands; Macromolecular Substances; Mutagenesis, Site-Directed; Spectrometry, Fluorescence; Tetrahydrofolates; Thermodynamics; Thymidine Monophosphate; Thymidylate Synthase	1999
Effects of subunit occupancy on partitioning of an intermediate in thymidylate synthase mutants. Biochemistry, 2000, Mar-14, Volume: 39, Issue:10 Topics: Alanine; Arginine; Catalysis; Deoxyuracil Nucleotides; Escherichia coli; Glycine; Kinetics; Lacticaseibacillus casei; Models, Chemical; Mutagenesis, Site-Directed; Peptide Fragments; Tetrahydrofolates; Thymidine Monophosphate; Thymidylate Synthase; Valine	2000
A deoxyribonucleotidase in mitochondria: involvement in regulation of dNTP pools and possible link to genetic disease. Proceedings of the National Academy of Sciences of the United States of America, 2000, Jul-18, Volume: 97, Issue:15 Topics: 5'-Nucleotidase; Abnormalities, Multiple; Amino Acid Sequence; Animals; Base Sequence; Brain; Cell Line; Deoxyuracil Nucleotides; DNA, Complementary; Genetic Diseases, Inborn; Humans; Mice; Mitochondria, Muscle; Molecular Sequence Data; Myocardium; Nucleotides; Purine-Pyrimidine Metabolism, Inborn Errors; Rats; Substrate Specificity; Thymidine Monophosphate; Tissue Distribution	2000
Novel RNA catalysts for the Michael reaction. Chemistry & biology, 2001, Volume: 8, Issue:5 Topics: Base Sequence; Cloning, Molecular; Deoxyuracil Nucleotides; Evolution, Chemical; Gene Library; Kinetics; Molecular Sequence Data; Oligonucleotides; RNA, Catalytic; Selection, Genetic; Substrate Specificity; Thymidine Monophosphate; Thymidylate Synthase	2001
An alternative flavin-dependent mechanism for thymidylate synthesis. Science (New York, N.Y.), 2002, Jul-05, Volume: 297, Issue:5578 Topics: Catalysis; Deoxyuracil Nucleotides; Electron Transport; Escherichia coli; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Gene Transfer, Horizontal; Genes, Archaeal; Genes, Bacterial; Helicobacter pylori; Molecular Weight; Phylogeny; Pyrococcus; Recombinant Proteins; Tetrahydrofolates; Thymidine Monophosphate; Thymidylate Synthase; Transformation, Bacterial; Uridine Monophosphate	2002
Biochemistry. DNA building block reinvented. Science (New York, N.Y.), 2002, Jul-05, Volume: 297, Issue:5578 Topics: Bacteria; Binding Sites; Crystallography, X-Ray; Deoxyuracil Nucleotides; Drug Design; Enzyme Inhibitors; Evolution, Molecular; Flavin-Adenine Dinucleotide; Helicobacter pylori; Humans; Methyltransferases; Models, Molecular; Phylogeny; Protein Conformation; Protein Structure, Tertiary; Protozoan Proteins; Tetrahydrofolates; Thermotoga maritima; Thymidine Monophosphate; Thymidylate Synthase	2002
Functional analysis of FAD-dependent thymidylate synthase ThyX from Paramecium bursaria Chlorella virus-1. The Journal of biological chemistry, 2004, Dec-24, Volume: 279, Issue:52 Topics: Animals; Chlorella; Cloning, Molecular; Deoxyuracil Nucleotides; DNA, Viral; Enzyme Inhibitors; Escherichia coli; Flavin-Adenine Dinucleotide; Gene Expression; Nucleic Acid Hybridization; Oxidation-Reduction; Paramecium; Phycodnaviridae; RNA; Thymidine Monophosphate; Thymidylate Synthase; Transcription, Genetic; Virus Replication	2004
Catalytic mechanism of Chlamydia trachomatis flavin-dependent thymidylate synthase. The Journal of biological chemistry, 2005, Feb-18, Volume: 280, Issue:7 Topics: Amino Acid Sequence; Catalysis; Chlamydia trachomatis; Cloning, Molecular; Deoxyuracil Nucleotides; Drug Design; Escherichia coli; Flavins; Folic Acid; Genetic Complementation Test; Kinetics; Molecular Sequence Data; NADP; Open Reading Frames; Oxidation-Reduction; Recombinant Proteins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Substrate Specificity; Thymidine Monophosphate; Thymidylate Synthase	2005
Direct observation of the participation of flavin in product formation by thyX-encoded thymidylate synthase. Journal of the American Chemical Society, 2005, Jan-26, Volume: 127, Issue:3 Topics: Campylobacter jejuni; Deoxyuracil Nucleotides; Flavin-Adenine Dinucleotide; Oxidation-Reduction; Spectrophotometry; Tetrahydrofolates; Thymidine Monophosphate; Thymidylate Synthase	2005
Crystal structures of thymidylate synthase mutant R166Q: structural basis for the nearly complete loss of catalytic activity. Journal of biochemical and molecular toxicology, 2006, Volume: 20, Issue:2 Topics: Amino Acid Substitution; Arginine; Binding Sites; Catalysis; Crystallization; Crystallography, X-Ray; Deoxyuracil Nucleotides; Dimerization; Escherichia coli; Folic Acid; Folic Acid Antagonists; Hydrogen Bonding; Kinetics; Ligands; Models, Molecular; Molecular Structure; Protein Binding; Protein Conformation; Recombinant Proteins; Thymidine Monophosphate; Thymidylate Synthase	2006
Biochemistry: Anchors away. Nature, 2009, Apr-16, Volume: 458, Issue:7240 Topics: Biocatalysis; Catalytic Domain; Crystallography, X-Ray; Deoxyuracil Nucleotides; Flavin-Adenine Dinucleotide; Flavins; Helicobacter pylori; Humans; Thermotoga maritima; Thymidine Monophosphate; Thymidylate Synthase; Uracil	2009
An unusual mechanism of thymidylate biosynthesis in organisms containing the thyX gene. Nature, 2009, Apr-16, Volume: 458, Issue:7240 Topics: Biocatalysis; Catalytic Domain; Crystallography, X-Ray; Deoxyuracil Nucleotides; Deuterium; Electrons; Flavin-Adenine Dinucleotide; Flavins; Helicobacter pylori; Humans; Magnetic Resonance Spectroscopy; Methylation; Models, Molecular; Mycobacterium tuberculosis; Protons; Thermotoga maritima; Thymidine; Thymidine Monophosphate; Thymidylate Synthase; Uracil	2009
Simultaneous quantification of 5-FU, 5-FUrd, 5-FdUrd, 5-FdUMP, dUMP and TMP in cultured cell models by LC-MS/MS. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2009, Oct-01, Volume: 877, Issue:27 Topics: Cell Line; Cell Line, Tumor; Chromatography, Liquid; Deoxyuracil Nucleotides; Drug Stability; Floxuridine; Fluorodeoxyuridylate; Fluorouracil; Humans; Reproducibility of Results; Sensitivity and Specificity; Solid Phase Extraction; Tandem Mass Spectrometry; Thymidine Monophosphate	2009
Novel positron emission tomography tracer distinguishes normal from cancerous cells. The Journal of biological chemistry, 2011, Sep-30, Volume: 286, Issue:39 Topics: Cell Division; Cell Line, Tumor; Deoxyuracil Nucleotides; DNA Replication; DNA, Neoplasm; Humans; Methylation; Neoplasm Proteins; Neoplasms; Positron-Emission Tomography; Radioactive Tracers; Radiography; Tetrahydrofolates; Thymidine Monophosphate; Thymidylate Synthase	2011
Raltitrexed's effect on the development of neural tube defects in mice is associated with DNA damage, apoptosis, and proliferation. Molecular and cellular biochemistry, 2015, Volume: 398, Issue:1-2 Topics: Animals; Apoptosis; Blotting, Western; Cell Proliferation; Deoxyuracil Nucleotides; DNA Damage; Embryo, Mammalian; Female; Folic Acid Antagonists; Gestational Age; Histones; Injections, Intraperitoneal; Male; Mice, Inbred C57BL; Neural Tube Defects; Phosphorylation; Pregnancy; Protein Subunits; Quinazolines; Replication Protein A; Thiophenes; Thymidine Monophosphate; Thymidylate Synthase	2015