2--deoxytubercidin and isoguanosine

2--deoxytubercidin has been researched along with isoguanosine* in 1 studies

Other Studies

1 other study(ies) available for 2--deoxytubercidin and isoguanosine

ArticleYear
Probing DNA interstrand cross-link formation by an oxidized abasic site using nonnative nucleotides.
    Bioorganic & medicinal chemistry, 2011, Oct-01, Volume: 19, Issue:19

    The C4'-oxidized abasic site (C4-AP) forms two types of interstrand cross-links with the adjacent nucleotides in DNA. Previous experiments revealed that dG does not react with the lesion and that formation of one type of cross-link is catalyzed by the opposing dA. iso-Guanosine·dC and 2-aminopurine·dT base pairs were used to determine why dG does not cross-link with C4-AP despite its well known reactivity with other bis-electrophiles. 7-Deaza-2'-deoxyadenosine was used to probe the role of the nucleotide opposite C4-AP in the catalysis of interstrand cross-link formation.

    Topics: 2-Aminopurine; Adenosine; Catalysis; Cross-Linking Reagents; DNA; Guanosine; Models, Molecular; Oxidation-Reduction; Tubercidin

2011