2--azido-2--deoxyuridine and tetrahydrofuran

2--azido-2--deoxyuridine has been researched along with tetrahydrofuran* in 1 studies

Other Studies

1 other study(ies) available for 2--azido-2--deoxyuridine and tetrahydrofuran

ArticleYear
2D IR photon echo of azido-probes for biomolecular dynamics.
    Physical chemistry chemical physics : PCCP, 2011, Feb-14, Volume: 13, Issue:6

    The vibrations in the azido-, N(3), asymmetric stretching region of 2'-azido-2'-deoxyuridine (N(3)dU) are examined by two-dimensional infrared spectroscopy. In water and tetrahydrofuran (THF), the spectra display a single sharp diagonal peak that shows solvent sensitivity. The frequency-frequency correlation time in water is 1.5 ps, consistent with H-bond making and breaking dynamics. The 2D IR spectrum is reproduced for N(3)dU in water based on a model correlation function and known linear response functions. Its large extinction coefficient, vibrational frequency outside the protein and nucleic acid IR absorption, and sensitivity to water dynamics render -N(3) a very useful probe for 2D IR and other nonlinear IR studies: its signal is ca. 100 times that of nitriles.

    Topics: Azides; Deoxyuridine; Furans; Hydrogen Bonding; Molecular Dynamics Simulation; Nitriles; Spectrophotometry, Infrared; Water

2011