Compounds > 2',6'-pipecoloxylidide
Page last updated: 2024-09-03

2',6'-pipecoloxylidide and lidocaine

2',6'-pipecoloxylidide has been researched along with lidocaine in 5 studies

Compound Research Comparison

Studies
(2',6'-pipecoloxylidide)		Trials
(2',6'-pipecoloxylidide)		Recent Studies (post-2010)
(2',6'-pipecoloxylidide)		Studies
(lidocaine)		Trials
(lidocaine)		Recent Studies (post-2010) (lidocaine)
342226,0905,9045,591

Protein Interaction Comparison

ProteinTaxonomy2',6'-pipecoloxylidide (IC50)lidocaine (IC50)
Sodium channel protein type 4 subunit alphaHomo sapiens (human)2

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19901 (20.00)18.7374
1990's3 (60.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ericson, J; Lesko, LJ; Marion, A; Ostheimer, G1
Attolini, L; Bruguerolle, B; Lorec, AM; Roucoules, X1
Butterworth, J; Grimes, J; James, RL1
Bruguerolle, B; Gamerre, M; Lorec, AM; Martin, C; Ortega, D; Viviand, X1
Honda, K; Inomata, S; Nakamura, T; Tanaka, E1

Other Studies

5 other study(ies) available for 2',6'-pipecoloxylidide and lidocaine

ArticleYear
Simultaneous determination of bupivacaine and 2,6-pipecoloxylidide in serum by gas-liquid chromatography.
    Journal of chromatography, 1980, May-09, Volume: 182, Issue:2

    Topics: Bupivacaine; Chromatography, Gas; Female; Fetal Blood; Humans; Infant, Newborn; Labor, Obstetric; Lidocaine; Maternal-Fetal Exchange; Pregnancy

1980
Rapid simultaneous determination of lidocaine, bupivacaine, and their two main metabolites using capillary gas-liquid chromatography with nitrogen phosphorus detector.
    Therapeutic drug monitoring, 1994, Volume: 16, Issue:6

    Topics: Bupivacaine; Chromatography, Gas; Humans; Lidocaine; Nitrogen; Phosphorus; Reproducibility of Results

1994
Structure-affinity relationships and stereospecificity of several homologous series of local anesthetics for the beta2-adrenergic receptor.
    Anesthesia and analgesia, 1997, Volume: 85, Issue:2

    Topics: Adrenergic beta-2 Receptor Antagonists; Adrenergic beta-Antagonists; Adult; Alkanes; Amides; Anesthetics, Local; Blood Vessels; Bupivacaine; Cyclic AMP; Dihydroalprenolol; Drug Overdose; Etidocaine; Female; Heart; Humans; Injections, Intravenous; Lidocaine; Ligands; Male; Mepivacaine; Molecular Conformation; Molecular Structure; Nerve Block; Pipecolic Acids; Prilocaine; Procaine; Receptors, Adrenergic, beta-2; Ropivacaine; Stereoisomerism; Structure-Activity Relationship; Tetracaine; Tritium

1997
Excretion of lidocaine and bupivacaine in breast milk following epidural anesthesia for cesarean delivery.
    Acta anaesthesiologica Scandinavica, 1999, Volume: 43, Issue:4

    Topics: Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthetics, Local; Apgar Score; Area Under Curve; Bupivacaine; Cesarean Section; Chromatography, Gas; Female; Follow-Up Studies; Humans; Infant, Newborn; Lidocaine; Milk, Human; Pregnancy; Safety

1999
Effects of premedication medicines on the formation of the CYP3A4-dependent metabolite of ropivacaine, 2', 6'-Pipecoloxylidide, on human liver microsomes in vitro.
    Basic & clinical pharmacology & toxicology, 2006, Volume: 98, Issue:2

    Topics: Amides; Anesthetics, Local; Bupivacaine; Cells, Cultured; Cimetidine; Clonidine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Diazepam; Drug Interactions; Humans; Lidocaine; Microsomes, Liver; Midazolam; Premedication; Ropivacaine; Thiamylal; Vecuronium Bromide

2006