Page last updated: 2024-09-03

2',6'-dimethyltyrosine and enkephalin, leucine

2',6'-dimethyltyrosine has been researched along with enkephalin, leucine in 2 studies

Compound Research Comparison

Studies (2',6'-dimethyltyrosine)	Trials (2',6'-dimethyltyrosine)	Recent Studies (post-2010) (2',6'-dimethyltyrosine)	Studies (enkephalin, leucine)	Trials (enkephalin, leucine)	Recent Studies (post-2010) (enkephalin, leucine)
27	0	6	11,524	80	754

Protein Interaction Comparison

Protein	Taxonomy	enkephalin, leucine (IC50)
Delta-type opioid receptor	Mus musculus (house mouse)	0.0142
Kappa-type opioid receptor	Mus musculus (house mouse)	0.0417
Mu-type opioid receptor	Homo sapiens (human)	9.5
Mu-type opioid receptor	Mus musculus (house mouse)	0.0308
Mu-type opioid receptor	Cavia porcellus (domestic guinea pig)	0.246

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (100.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Anthony, E; Beardsley, PM; Chandrakumar, NS; Drury, B; Lopez, OT; Reichman, M; Savage, MA; Stapelfeld, A; Williamson, LN	1
Ambo, A; Ouchi, H; Sasaki, Y; Suto, T; Yamamoto, Y	1

Other Studies

2 other study(ies) available for 2',6'-dimethyltyrosine and enkephalin, leucine

Article	Year
Analogs of the delta opioid receptor selective cyclic peptide [2-D-penicillamine,5-D-penicillamine]-enkephalin: 2',6'-dimethyltyrosine and Gly3-Phe4 amide bond isostere substitutions. Journal of medicinal chemistry, 1992, Aug-07, Volume: 35, Issue:16 Topics: Amides; Amino Acid Sequence; Analgesics; Animals; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Glycine; Male; Mice; Molecular Sequence Data; Muscle Contraction; Neuroblastoma; Peptides, Cyclic; Phenylalanine; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Structure-Activity Relationship; Substrate Specificity; Tumor Cells, Cultured; Tyrosine; Vas Deferens	1992
Biological properties of opioid peptides replacing Tyr at position 1 by 2,6-dimethyl-Tyr. Chemical & pharmaceutical bulletin, 1999, Volume: 47, Issue:10 Topics: Animals; Enkephalin, Leucine; Guinea Pigs; Isomerism; Mice; Opioid Peptides; Rats; Receptors, Opioid; Structure-Activity Relationship; Tyrosine	1999

Article

Year

Analogs of the delta opioid receptor selective cyclic peptide [2-D-penicillamine,5-D-penicillamine]-enkephalin: 2',6'-dimethyltyrosine and Gly3-Phe4 amide bond isostere substitutions.

Journal of medicinal chemistry, 1992, Aug-07, Volume: 35, Issue:16

Topics: Amides; Amino Acid Sequence; Analgesics; Animals; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Glycine; Male; Mice; Molecular Sequence Data; Muscle Contraction; Neuroblastoma; Peptides, Cyclic; Phenylalanine; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Structure-Activity Relationship; Substrate Specificity; Tumor Cells, Cultured; Tyrosine; Vas Deferens

1992

Biological properties of opioid peptides replacing Tyr at position 1 by 2,6-dimethyl-Tyr.

Chemical & pharmaceutical bulletin, 1999, Volume: 47, Issue:10

Topics: Animals; Enkephalin, Leucine; Guinea Pigs; Isomerism; Mice; Opioid Peptides; Rats; Receptors, Opioid; Structure-Activity Relationship; Tyrosine

1999